- Marine Polysaccharide (Chitosan) and Its Derivatives as Water Purifier

2013 ◽  
pp. 770-787 ◽  
Marine Drugs ◽  
2021 ◽  
Vol 19 (6) ◽  
pp. 345
Author(s):  
Ying Sun ◽  
Xiaoli Ma ◽  
Hao Hu

Marine biomass is a treasure trove of materials. Marine polysaccharides have the characteristics of biocompatibility, biodegradability, non-toxicity, low cost, and abundance. An enormous variety of polysaccharides can be extracted from marine organisms such as algae, crustaceans, and microorganisms. The most studied marine polysaccharides include chitin, chitosan, alginates, hyaluronic acid, fucoidan, carrageenan, agarose, and Ulva. Marine polysaccharides have a wide range of applications in the field of biomedical materials, such as drug delivery, tissue engineering, wound dressings, and sensors. The drug delivery system (DDS) can comprehensively control the distribution of drugs in the organism in space, time, and dosage, thereby increasing the utilization efficiency of drugs, reducing costs, and reducing toxic side effects. The nano-drug delivery system (NDDS), due to its small size, can function at the subcellular level in vivo. The marine polysaccharide-based DDS combines the advantages of polysaccharide materials and nanotechnology, and is suitable as a carrier for different pharmaceutical preparations. This review summarizes the advantages and drawbacks of using marine polysaccharides to construct the NDDS and describes the preparation methods and modification strategies of marine polysaccharide-based nanocarriers.


2018 ◽  
Vol 75 (7) ◽  
pp. 925-933 ◽  
Author(s):  
Kris Niño G. Valdehuesa ◽  
Kristine Rose M. Ramos ◽  
Llewelyn S. Moron ◽  
Imchang Lee ◽  
Grace M. Nisola ◽  
...  

2018 ◽  
Vol 43 ◽  
pp. 353-361 ◽  
Author(s):  
Jiaqi Yin ◽  
Weijian Wang ◽  
Xuelian Xu ◽  
Hongxia Li ◽  
Mengyi Cong ◽  
...  

2020 ◽  
Vol 141 ◽  
pp. 103973 ◽  
Author(s):  
Durairajan Rubini ◽  
Prakash Vishnu Varthan ◽  
Senthilganesh Jayasankari ◽  
B. Narayanan Vedahari ◽  
Paramasivam Nithyanand

Marine Drugs ◽  
2019 ◽  
Vol 17 (4) ◽  
pp. 197 ◽  
Author(s):  
Wei Zhang ◽  
Takasi Okimura ◽  
Tatsuya Oda ◽  
Jun-O Jin

Natural marine polysaccharides have demonstrated immune stimulatory effects in both mice and humans. Our previous study compared the ability of ascophyllan and fucoidan to activate human and mouse dendritic cells (DCs). In this study, we further examined the effect of ascophyllan on the activation of mouse natural killer (NK) cells in vivo and in vitro and compared it to that of fucoidan, a well-studied natural marine polysaccharide. Specifically, administration of ascophyllan to C57BL/6 mice increased the number of NK cells in the spleen when compared to the number in PBS-treated mice. Moreover, the number of IFN-γ-producing NK cells and expression of CD69 were markedly upregulated by ascophyllan treatment. Ascophyllan treatment also induced IFN-γ production and CD69 upregulation in isolated NK cells, but did not promote cell proliferation. Finally, ascophyllan treatment increased the cytotoxicity of NK cells against Yac-1 cells. The effects of ascophyllan on NK cell activation were considerably stronger than those of fucoidan. These data demonstrated that ascophyllan promotes NK cell activation both in mice and in vitro, and its stimulatory effect on NK cells is stronger than that of fucoidan.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Nathalie Chopin ◽  
Corinne Sinquin ◽  
Jacqueline Ratiskol ◽  
Agata Zykwinska ◽  
Pierre Weiss ◽  
...  

GY785 is an exopolysaccharide produced by a mesophilic bacterial strainAlteromonas infernusdiscovered in the deep-sea hydrothermal vents. GY785 highly sulfated derivative (GY785 DRS) was previously demonstrated to be a promising molecule driving the efficient mesenchymal stem cell chondrogenesis for cartilage repair. This glycosaminoglycan- (GAG-) like compound was modified in a classical solvent (N,N′-dimethylformamide). However, the use of classical solvents limits the polysaccharide solubility and causes the backbone degradation. In the present study, a one-step efficient sulfation process devoid of side effects (e.g., polysaccharide depolymerization and/or degradation) was developed to produce GAG-like derivatives. The sulfation of GY785 derivative (GY785 DR) was carried out using ionic liquid as a reaction medium. The successful sulfation of this anionic and highly branched heteropolysaccharide performed in ionic liquid would facilitate the production of new molecules of high specificity for biological targets such as tissue engineering or regenerative medicine.


2020 ◽  
Vol 19 (6) ◽  
pp. 2767-2796 ◽  
Author(s):  
Huihui Sun ◽  
Li Gao ◽  
Changhu Xue ◽  
Xiangzhao Mao

2020 ◽  
Vol 1007 ◽  
pp. 131-136
Author(s):  
Suyeon Kim ◽  
Mariela Elgegren ◽  
Alonso Donayre ◽  
Betty Galaretta ◽  
Javier Nakamatsu

In this research, the nanostructured alginate (AL) membranes were prepared with natural bioactive compound, Cat's claw (Uncaria tomentosa) extract (UT). UT is broadly used as an anti-inflammatory agent and the effect on the treatment of Rheumatism was proved by many scientists. For this reason, we added this bioactive compound in the process of AL membrane formulation to improve the biological activities. 2-dimentional (2-D) and 3-dimentional (3-D) AL membranes were prepared with and without addition of UT extracts. 3-D AL membranes were prepared using ultrasound with high intensity. The wettability of AL membranes depending on the concentration of AL was studied by measuring contact angle and surface energy. Stabilization agent, poloxamer 407, was used to improve the stability of AL nanoemulsion. The effects of UT in 3-D AL membranes were studied by measuring swelling behavior and contact angle. The surface morphology was measured with scanning electron microscopy (SEM). Comparing to 2-D AL membranes, 3-D AL membranes presented rougher surface due to AL nanoparticles presence. When UT was incorporated in AL membranes, strong antioxidant activity and higher contact angle and swelling ratio were observed than non-UT incorporated AL membranes.


2013 ◽  
Vol 14 (10) ◽  
pp. 20064-20078 ◽  
Author(s):  
Vesna Svetličić ◽  
Vera Žutić ◽  
Galja Pletikapić ◽  
Tea Radić

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