Changes in the Growth and Body Collagen of Suckling Rats Caused by the Treatment of Lactating Mothers with Cortisone

Endocrinology ◽  
1969 ◽  
Vol 84 (2) ◽  
pp. 432-434 ◽  
Author(s):  
K. KOWALEWSKI
Keyword(s):  
Suckling Rats ◽  
Lactating Mothers

scholarly journals Changes in drug-metabolizing activities in the livers of suckling rats as a result of treatment of the lactating mothers with phenobarbitone and chlorpromazine

1971 ◽  
Vol 122 (1) ◽  
pp. 41-47 ◽  
Author(s):  
F. J. Darby
Keyword(s):  
Cytochrome C ◽  
Drug Metabolism ◽  
Female Rats ◽  
Suckling Rats ◽  
Cytochrome C Reductase ◽  
Nadph Cytochrome ◽  
Lactating Mothers ◽  
Cytochrome P 450 ◽  
Nadph Cytochrome C Reductase

1. Lactating female rats were treated with phenobarbitone or chlorpromazine. 2. Hepatic microsomal fractions from the suckling offspring were studied to see if changes had occurred in the rates of drug metabolism. 3. Treatment with phenobarbitone significantly increased the cytochrome P-450 concentration, the activity of NADPH–cytochrome c reductase (EC 1.6.2.3) and the rates of metabolism of aniline, ethylmorphine and [2-14C]pentobarbitone. 4. Treatment with chlorpromazine produced only small increases in the cytochrome P-450 concentration and the rate of hydroxylation of aniline.

Services Provided for Lactating Mothers at Lactation Management Clinic in Selected Tertiary Level Hospitals

2020 ◽  
Vol 38 (2) ◽  
pp. 68-73
Author(s):  
Tarannum Tasnim ◽  
ANM Shamsul Islam ◽  
Mehedi Hasan Azad ◽  
Farhana Sharmin
Keyword(s):  
Breast Milk ◽  
Milk Production ◽  
Public Awareness ◽  
Cross Sectional Study ◽  
Dietary Advice ◽  
Tertiary Level ◽  
Cross Sectional ◽  
Breast Milk Production ◽  
Lactating Mothers ◽  
Structured Questionnaire

Background: Children are the precious gift from the Almightily Allah and breast milk is an ideal product given to the human being by nature to fulfill all requirements of the offspring until they are matured enough to take adult food. Objective: To assess the services provided for lactating mothers at lactation management centre in selected tertiary level hospitals. Materials and Methods: This cross sectional study was conducted among 100 Lactating mothers who were selected conveniently and were interviewed by pre-tested semi-structured questionnaire and an observational checklist. Collected data were processed and analyzed using SPSS (Statistical Packages for Social Science) software. Results: Lactation management centre (LMC) is supervised by a consultant and separate room is allotted in both out-patient and in-patient departments. Mothers came with lactation problems were more likely in the first month of the baby (73%) and feeling of not enough milk production was common (49%).Highly significant relationship was found between breast problems of lactating mother and age of child (p<0.001). About 84% respondents received practical demonstration on position and attachment of the baby during lactation. About 91% respondents got dietary advice for enough breast milk production, 75% got dietary advice regarding their child’s weaning food chart and69% got health education. Maximum mothers were informed about LMC by doctor & nurse (82%). Conclusion: Information about LMC services should be disseminated across the country. Lactating mothers should be familiarized with LMC and public awareness should be enhanced for effective management of breastfeeding problem to promote, protect and support the breastfeeding. JOPSOM 2019; 38(2): 68-73

Queixas de nutrizes que buscam atendimento em um banco de leite humano e fatores associados

2019 ◽  
Vol 87 (25) ◽  
Author(s):  
Lara Thaiane Souza Pereira ◽  
Taynara Cassimiro de Moura Alves ◽  
Nathalya da Silva Louro ◽  
Nayara Franklin Cesar ◽  
Juliana das Dores Ferreira ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Data Collection ◽  
Women's Health ◽  
Breast Feeding ◽  
Reliable Information ◽  
Previous Experience ◽  
Cross Sectional ◽  
Lactating Mothers ◽  
Milk Banks ◽  
Nutrient Conditions

O objetivo deste artigo é analisar as queixas de nutrizes que buscaram atendimento em um BLH e fatores associados.Trata-se de um estudo descritivo, analítico, transversal, retrospectivo, cuja população é composta por 1.709 nutrizes quebuscaram atendimento no período de Janeiro a Dezembro de 2016. Para a coleta de dados, utilizaram-se as fichas deatendimento do BLH. As principais queixas que levaram as nutrizes a buscarem atendimento no BLH relacionam-se àdificuldade com a técnica de amamentação (41,9%) e a problemas mamários, como o ingurgitamento mamário (27,1%) eo trauma mamilar (18,1%). A necessidade de auxílio na técnica de amamentação esteve associada às seguintes condiçõesrelativas à nutriz: ser procedente da capital (p=0,001), apresentar mais de oito anos de estudo (p=0,040), ter uma ocupação (p=0,010), ser primípara (p=<0,001), optar pela realização de parto cesárea (p=<0,001) e ter experiência préviacom amamentação (p=0,004). Houve associação entre ingurgitamento mamário e primiparidade (p=0,038), além do fatode a nutriz ter contado com o apoio ao aleitamento materno na maternidade (p=0,021). O estudo possibilitou verificar aimportância dos BLH no processo de lactação, um período em que as mulheres ficam ansiosas, necessitam de informaçõesconfiáveis e apresentam muitas queixas em relação à lactação.PALAVRAS-CHAVES : Aleitamento materno, Bancos de leite, Saúde da mulher. Abstract: The aim of this article is to analyze the complaints of lactating mothers who sought care in a HMB and associatedfactors. It is a descriptive, cross-sectional, retrospective study, whose population is composed of 1.709 lactating mothers whosought care in the period from January to December the 2016. For the data collection, were used the service records ofthe HMB. The main complaints that led the lactating mothers to seek care at HMB were related to the difficulty with thebreastfeeding technique (41.9%) and to breast problems, such as breast engorgement (27.1%) and nipple trauma (18,1%). Theneed for breastfeeding technique was associated to the following nutrient conditions: coming from the capital (p = 0.001),presenting more than eight years of study (p = 0.040), having an occupation (p = 0.010), being primiparous (p = <0.001), optfor cesarean (p = 0.001) and to have previous experience with breastfeeding (p = 0.004). There was an association betweenbreast engorgement and primiparity (p = 0.038), in addition to the fact that the mother had support for breastfeeding in thematernity ward (p = 0.021). The study made it possible to verify the importance of HMBs in the lactation process, a period inwhich women become anxious, require reliable information and have many complaints about lactation.Keywords: Breast feeding, Milk banks, Women’s health

Across The “Sweetiest” Properties Of Human Breast Milk: Focus On Oligosaccharides

2020 ◽  
Vol 16 ◽  
Author(s):  
Flaminia Bardanzellu ◽  
Alessandra Reali ◽  
Maria Antonietta Marcialis ◽  
Vassilios Fanos
Keyword(s):  
Breast Milk ◽  
Active Role ◽  
Individual Variability ◽  
Human Breast Milk ◽  
Formula Milk ◽  
Target Organs ◽  
Lactating Mothers ◽  
Neonatal Nutrition ◽  
Genetic And Environmental Factors ◽  
Systemic Infections

Introduction: Breast Milk (BM), containing nutrients and bioactive components, represents the best source for neonatal nutrition and determines short- and long- term benefits. Human milk oligosaccharides (HMOs) play an active role in these pathophysiological mechanisms. In fact; they influence the shaping of breastfed infant’s gut microbiota, promote intestinal development, confer protection against intestinal or systemic infections modulating immune system; moreover, HMOs determine extra-intestinal effects on several target organs, i.e reducing necrotizing enterocolitis rate or improving brain development. Aims: In this review, we analyze the great inter- and intra-individual variability of BM HMOs, investigating maternal, genetic and environmental factors modulating their composition. Moreover, we provide an update regarding HMOs’ unique properties, underlining their complex interaction with intestinal microbiota and host-derived metabolites. The possible HMOs’ influence on extra-intestinal bacterial communities, potentially influencing newborns’ and even lactating mothers’ health, have been hypothesized. Finally, recognized HMOs’ crucial role, we underline the promising opportunities showed by their addition in formula milk, useful to create dairy products more similar to maternal milk itself.

scholarly journals Impact of Maternal Daily Oral Low-Dose Vitamin A Supplementation on the Mother–Infant Pair: A Randomised Placebo-Controlled Trial in China

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2370
Author(s):  
Ye Ding ◽  
Ping Hu ◽  
Yue Yang ◽  
Fangping Xu ◽  
Fang Li ◽  
...  
Keyword(s):  
Health Status ◽  
Breast Milk ◽  
Vitamin A ◽  
Low Dose ◽  
Maternal Serum ◽  
Control Group ◽  
Vitamin A Supplementation ◽  
Maternal Vitamin ◽  
Vitamin A Status ◽  
Lactating Mothers

Background: The nutritional status of vitamin A in lactating mothers and infants is still not optimistic. Due to the dietary habits and dietary restrictions of postpartum customs in China, vitamin A supplementation has been advocated as a potential strategy to improve vitamin A status of lactating mothers with inadequate dietary vitamin A intake. Existing clinical trials are limited to single or double high-dose maternal administrations. However, in China, vitamin A supplements are readily available in the form of daily oral low-dose supplements, and the effect of these is unknown. This study aimed to evaluate the effects of daily oral low-dose vitamin A supplementation on the retinol levels in the serum and breast milk of lactating mothers and the health status of infants in China. Methods: Lactating mothers who met the inclusion criteria and planned to continue exclusive breastfeeding were randomly assigned to receive either daily oral vitamin A and D drops (one soft capsule of 1800 IU vitamin A and 600 IU vitamin D2), or a matching placebo for 2 months. Before and after the intervention, dietary intake was investigated by instant photography, and the retinol concentration in maternal serum and breast milk was determined by ultra-high performance liquid chromatography-tandem mass spectrometry. During the trial, the health status of infants was diagnosed by a paediatrician or reported by lactating mothers. A total of 245 participants completed the study, with 117 in the supplementation group and 128 in the control group. Results: After the 2-month intervention, maternal serum retinol concentrations increased in the supplementation group with no change in the control group. Although breast milk retinol concentrations decreased significantly in both groups, the decrease in the supplementation group was significantly lower than that in the control group. However, maternal vitamin A supplementation was not associated with a lower risk of infant febrile illness, respiratory tract infection, diarrhoea, and eczema. Conclusions: Daily oral low-dose vitamin A supplementation is helpful in improving maternal vitamin A status, despite having no effect on infant health status through breast milk.

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