scholarly journals Effects of Depot Medroxyprogesterone Acetate on Bone Density and Bone Metabolism before and after Peak Bone Mass: A Case-Control Study

2008 ◽  
Vol 93 (4) ◽  
pp. 1317-1323 ◽  
Author(s):  
Jennifer S. Walsh ◽  
Richard Eastell ◽  
Nicola F. A. Peel
2005 ◽  
Vol 73 (2-3) ◽  
pp. 351-355 ◽  
Author(s):  
Nadja Maric ◽  
Vera Popovic ◽  
Miroslava Jasovic-Gasic ◽  
Nada Pilipovic ◽  
Jim van Os

2012 ◽  
Vol 119 (6) ◽  
pp. 672-677 ◽  
Author(s):  
S Wilailak ◽  
C Vipupinyo ◽  
V Suraseranivong ◽  
K Chotivanich ◽  
C Kietpeerakool ◽  
...  

2018 ◽  
Vol 44 (4) ◽  
pp. 242-247 ◽  
Author(s):  
Christina Lang ◽  
Zhong Eric Chen ◽  
Anne Johnstone ◽  
Sharon Cameron

ObjectivesThe primary objective of this study was to determine whether intramuscular depot medroxyprogesterone acetate (IM DMPA) given at the time of misoprostol administration, 24–48 hours after mifepristone, affects the rate of continuing pregnancy. In addition, the study explored factors predictive of continuing pregnancy.DesignCase-control study based on database review of women who underwent early medical abortion (EMA) over a 4-year period.SettingSingle abortion service in Scotland.Participants5122 women who underwent an EMA within the timeframe of this study.Main outcome measuresContinuing pregnancies among women receiving IM DMPA were compared with those choosing other hormonal methods of contraception, non-hormonal contraception or no contraception at the time of misoprostol administration. Logistic regression was performed to assess the effects of demographic characteristics, gestation at presentation and method of contraception provided, on outcome of pregnancy.ResultsA total of 4838 women with complete data were included, of which there were 20 continuing pregnancies (0.4%); 284 women were excluded due to missing data. There was no increased risk of a continuing pregnancy among women who initiated IM DMPA at the time of misoprostol administration (24–48 hours after mifepristone) compared with women who initiated no hormonal contraception at this time (RR 0.48; 95% CI 0.06 to 3.81). Gestation ≥8 weeks and previous terminations were factors associated with increased likelihood of continuing pregnancy.ConclusionsWomen choosing IM DMPA after EMA can be reassured that IM DMPA can be safely initiated at the time of misoprostol administration 24–48 hours after mifepristone without an increase in the risk of a continuing pregnancy. Both increasing gestation and previous termination were factors associated with an increased likelihood of continuing pregnancy following an EMA.


2016 ◽  
Vol 28 (1) ◽  
pp. 291-297 ◽  
Author(s):  
I. Kyvernitakis ◽  
K. Kostev ◽  
T. Nassour ◽  
F. Thomasius ◽  
P. Hadji

Author(s):  
Pisake Lumbiganon ◽  
Sungwal Rugpao ◽  
Surang Phandhu-fung ◽  
Malinee Laopaiboon ◽  
Nara Vudhikamraksa ◽  
...  

Author(s):  
Vánio André Mugabe ◽  
Arlete Mahumane ◽  
Cynthia Semá ◽  
Érika Valeska Rossetto ◽  
Crescêncio Sequeira Nhabomba ◽  
...  

In mid-June 2019, 3 months after cyclone Idai landfall in Mozambique, health authorities of Nhamatanda district reported an outbreak of Pellagra. Applying a mixed-method protocol, we carried out an investigation to characterize cases of pellagra, identify the associated factors for the outbreak using a case–control study, and explore the perceived impact on food security (availability, access, and usage) before and after Idai. We collected data from 121 cases and 121 controls and conducted in-depth interviews with 69 heads of households. The cases were more likely to be female (P < 0.01) and less educated (P < 0.01) than controls. Insufficient consumption of chicken and peanut before cyclone Idai arrival were statistically associated with pellagra (P < 0.05). From interviewed households’ heads, 51% were experiencing food shortages even before the cyclone hit. Cyclone Idai served as a trigger to reduce niacin consumption below the threshold that protected Nhamatanda population from pellagra and caused a ≈2,300 case (707.9/100,000 inhabitants) outbreak.


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