scholarly journals Increased Arterial Stiffness in Subjects with Impaired Glucose Tolerance and Newly Diagnosed Diabetes But Not Isolated Impaired Fasting Glucose

2012 ◽  
Vol 97 (4) ◽  
pp. E658-E662 ◽  
Author(s):  
Chung-Hao Li ◽  
Jin-Shang Wu ◽  
Yi-Ching Yang ◽  
Chi-Chen Shih ◽  
Feng-Hwa Lu ◽  
...  
Author(s):  
Thanh Long Le ◽  
Trung Vinh Hoang

Objective: To evaluate the prevalence of newly diagnosed prediabetes, diabetes mellitus among the officers from Phuoc Long district of Binh Phuoc province. Subjects and methods: 268 personals communications service was examined the impaired fasting glucose (G0); impaired glucose tolerance (G2) anh HbA1c. Results: Prevalence of prediabetes, type 2 diabetes mellitus by G0, G2, HbA1c as follows 16,0%; 13,1%; 17,9% and 3,8%; 6,7%; 2,2%. Common prevalence of prediabetes in 26,9%; type 2 diabetes mellitus in 7,1%. Conclusion: Personal communications service from Phuoc Long district have percentage of prediabetes higher compared to type 2 diabetes mellitus which of prediabetes was diagnosed by HbA1c which takes up the highest percentage; diabetes mellitus was diagnosed by G2which takes up the highest percentage.


2019 ◽  
Vol 8 (5) ◽  
pp. 603
Author(s):  
Chung-Hao Li ◽  
Feng-Hwa Lu ◽  
Yi-Ching Yang ◽  
Jin-Shang Wu ◽  
Chih-Jen Chang

Previous studies exploring the association between arterial stiffness and prediabetes remain controversial. This study aimed to investigate the association of the different domains of prediabetes categorized by glycated hemoglobin A1c (A1c) 5.7–6.4%, impaired fasting glucose (IFG), fasting plasma glucose of 5.6–6.9 mmol/L, and impaired glucose tolerance (IGT), two-hour post-load glucose of 7.8–11.0 mmol/L, on arterial stiffness. These were measured by brachial–ankle pulse-wave velocity (baPWV). We enrolled 4938 eligible subjects and divided them into the following nine groups: (1) normoglycemic; (2) isolated A1c 5.7–6.4%; (3) isolated IFG; (4) IFG with A1c 5.7–6.4%; (5) isolated IGT; (6) combined IGT and IFG with A1c <5.7%; (7) IGT with A1c 5.7–6.4%; (8) combined IGT and IFG with A1c 5.7–6.4%; and (9) newly diagnosed diabetes (NDD). The baPWV values were significantly high in subjects with NDD (β = 47.69, 95% confidence interval (CI) = 29.02–66.37, p < 0.001), those with IGT with A1c 5.7–6.4% (β = 36.02, 95% CI = 19.08–52.95, p < 0.001), and those with combined IGT and IFG with A1c 5.7–6.4% (β = 27.72, 95% CI = 0.68–54.76, p = 0.044), but not in the other subgroups. These findings suggest that increased arterial stiffness was found in prediabetes individuals having an A1c 5.7–6.4% with IGT, but not IFG. Isolated A1c 5.7–6.4% and isolated IGT were not associated with elevated arterial stiffness.


2013 ◽  
Vol 169 (3) ◽  
pp. e33-e34 ◽  
Author(s):  
Hao-Chang Hung ◽  
Feng-Hwa Lu ◽  
Horng-Yih Ou ◽  
Hung-Tsung Wu ◽  
Jin-Shang Wu ◽  
...  

2021 ◽  
Vol 37 (9) ◽  
Author(s):  
Aline Isabel Rodrigues Galvão ◽  
Alline Maria R. Beleigoli ◽  
Pedro Guatimosim Vidigal ◽  
Bruce Bartholow Duncan ◽  
Maria Inês Schmidt ◽  
...  

Abstract: There is a conflict in the literature regarding the association between serum uric acid (SUA) levels and glycemic status. Therefore, we evaluated the association between SUA level and glycemic status - impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes mellitus - and insulin resistance, in a large Brazilian study. This is a cross-sectional, observational study with 13,207 participants aged 35-74 years, at baseline (2008-2010) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). A multinomial regression analysis was performed to test the association between SUA and glycemic status (IFG, IGT, and newly diagnosed type 2 diabetes at the cohort baseline) after adjustments by age, sex, skin color, body mass index, physical activity, smoking, alcohol consumption, comorbidities, and medicines use. Logistic regression model was used to evaluate the association between SUA and insulin resistance by HOMA-IR. Stratified analyses by sex were performed. The mean age (standard deviation) was 51.4 (8.9) years, 55.2% of participants were women. There were 1,439 newly diagnosed diabetes. After all adjustments, higher SUA was associated with IFG, IGT, and diabetes, with odds ratio (OR) = 1.15 (95%CI: 1.06; 1.25), 1.23 (95%CI: 1.14; 1.33), and 1.37 (95%CI: 1.24; 1.51), respectively. There was association between SUA levels and insulin resistance with OR = 1.24 (95%CI: 1.13; 1.36). In analysis stratified by sex, higher SUA persisted independently associated with impaired glycemic status. Our results suggest that a higher SUA levels were significantly associated with glycemic status in a large Latin American population, mainly among women.


2015 ◽  
Vol 31 (8) ◽  
pp. 1295-1301 ◽  
Author(s):  
Zih-Jie Sun ◽  
Yi-Ching Yang ◽  
Jin-Shang Wu ◽  
Ming-Cheng Wang ◽  
Chih-Jen Chang ◽  
...  

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