Accumulation of High-Density Lipoprotein-Derived Estradiol-17  Fatty Acid Esters in Low-Density Lipoprotein Particles

2001 ◽  
Vol 86 (3) ◽  
pp. 1294-1300 ◽  
Author(s):  
H. Helisten
Keyword(s):  
Fatty Acid ◽  
High Density Lipoprotein ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Fatty Acid Esters ◽  
Low Density ◽  
Lipoprotein Particles ◽  
Acid Esters

scholarly journals Accumulation of High-Density Lipoprotein-Derived Estradiol-17β Fatty Acid Esters in Low-Density Lipoprotein Particles1

2001 ◽  
Vol 86 (3) ◽  
pp. 1294-1300 ◽  
Author(s):  
Hannamaarit Helisten ◽  
Anna Höckerstedt ◽  
Kristiina Wähälä ◽  
Aila Tiitinen ◽  
Herman Adlercreutz ◽  
...  
Keyword(s):  
Fatty Acid ◽  
High Density Lipoprotein ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Fatty Acid Esters ◽  
Low Density ◽  
Estradiol 17Β ◽  
Acid Esters

scholarly journals Effect of Unsaturated Fatty Acid Omega-3 on Some Biochemical Criteria in White New Zealand Rabbits Administrated with Cyclosporine Drug

2021 ◽  
Vol 2 (1) ◽  
pp. 15-24
Author(s):  
Murtadha M. Jawad
Keyword(s):  
Fatty Acid ◽  
Side Effects ◽  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
Unsaturated Fatty Acid ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Low Density ◽  
Omega 3

The present study was aimed efficiency to evaluate the unsaturated fatty acid omega-3 in reducing the side effects that resulted from the administration of cyclosporine drug in white rabbits. (60) white males' rabbits were used in this study, divided into four groups contain (15) rabbits per group and its subdivision into three groups (5) rabbits per group. The first group is orally administered with normal saline, the second group was administered cyclosporine (25mg/kg) only. Third groups were administered cyclosporine on the first day and omega-3 (500mg/kg) on the second day, while Fourth groups were administered cyclosporine on the first day and omega-3 (1000mg/kg) on the second day for periods (21,30,60) days respectively. After ending study periods, the animals were sacrificed and the blood was collected and the results were shown the following:  Administration with cyclosporine (25mg/kg)only and for periods were led to a significant increase(P<0.05) in total cholesterol, triglycerides and low-density lipoprotein(LDL) and a significant decrease(P<0.05) in high-density lipoprotein(HDL).whereas interaction with (500&1000mg/kg) of omega-3 and to all periods showed a significant decrease (p<0.05) in the total cholesterol, triglycerides and low-density lipoprotein(LDL) and significant decrease(p<0.05) in high-density lipoprotein(HDL), while the non-significant difference in high-density lipoprotein(HDL). This study concluded that omega-3 has an important role in reducing biochemistry side effects that result from the administration of cyclosporine drugs in white rabbits.

scholarly journals Hubungan Indonesian's Healthy Eating Index dengan Biomarker Sindrom Metabolik pada Penderita Penyakit Jantung Koroner (PJK)

2020 ◽  
Vol 7 (2) ◽  
pp. 139-152
Author(s):  
Dodik Briawan ◽  
Widya Lestari Nurpratama ◽  
Woro Riyadina
Keyword(s):  
Fatty Acid ◽  
High Density Lipoprotein ◽  
Polyunsaturated Fatty Acid ◽  
Healthy Eating ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Healthy Eating Index ◽  
High Density ◽  
Low Density

Penilaian konsumsi pangan dengan metode Healthy Eating Index (HEI) belum banyak dilakukan di Indonesia. Tujuan penelitian adalah untuk menganalisis hubungan HEI versi Indonesia dengan biomarker Sindrom Metabolik (SM) pada penderita Penyakit Jantung Koroner (PJK). Penelitian ini menggunakan data Studi Kohor Faktor Risiko Penyakit Tidak Menular periode tahun 2013-2016. Ditemukan sebanyak 124 kasus baru PJK berdasarkan pengukuran EKG. Pengukuran konsumsi pangan menggunakan konsumsi pangan 1x24 jam setahun sebelum subjek didiagnosa PJK. Penilaian kualitas diet dengan metode US-HEI yang dimodifikasi berdasarkan jumlah porsi pada pedoman gizi seimbang Indonesia. Data biomarker SM yang digunakan meliputi tekanan darah, glukosa darah puasa (GDP), glukosa darah pasca pembebanan (GD2PP), High Density Lipoprotein (HDL), Low Density Lipoprotein (LDL) dan trigliserida yang diukur pada saat pertama kali didiagnosis PJK. Rata-rata skor HEI yaitu 58.6, dan sebanyak 1.6% subjek termasuk kategori baik. Komponen HEI yaitu minuman berpemanis berhubungan signifikan dengan GDP (r=0.271), GD2PP (r=0.191), HDL (r=-0.200) (p<0.05); sedangkan skor Polyunsaturated Fatty Acid (PUFA) berhubungan signifikan dengan HDL (r=0.219) (p<0.05). Hasil studi mengonfirmasi kembali bahwa dalam program pencegahan PJK sebaiknya diikuti dengan mengurangi asupan gula dan meningkatkan konsumsi pangan sumber PUFA. Kata kunci: healthy eating index, konsumsi pangan, penyakit jantung koroner, sindrom metabolik

scholarly journals Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3

2000 ◽  
Vol 41 (9) ◽  
pp. 1495-1508 ◽  
Author(s):  
Mohamad Navab ◽  
Susan Y. Hama ◽  
G.M. Anantharamaiah ◽  
Kholood Hassan ◽  
Greg P. Hough ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Low Density ◽  
Oxidized Low Density Lipoprotein
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