Action of Triethanomelamine (TEM) on Early and Later Stages of Mouse Embryos

Development ◽  
1959 ◽  
Vol 7 (4) ◽  
pp. 526-539
Author(s):  
A. Jurand
Keyword(s):  
Cell Size ◽  
Nervous Tissue ◽  
Considerable Increase ◽  
Mouse Embryos ◽  
Stages Of Development ◽  
Embryonic Tissues ◽  
Early Stages ◽  
Inhibiting Property ◽  
Mutagenic Factor

Several years ago triethanomelamine (2, 4, 6-tri(ethyleneimino)-l, 3, 5-triazine, or TEM) was introduced into clinical chemotherapy for its tumour-inhibiting property. It was found, in addition, that TEM is a strong mutagenic factor. In a previous paper (Jurand, 1958) it was shown that TEM severely retards the development of the chick in the early embryonic stages. This effect is directly proportional to the dose of TEM used. It was suggested that the sensitivity of individual embryonic tissues varies in the early stages of development, somites being the most sensitive embryonic organs. There was observed also, especially with larger doses of TEM, a considerable widening of the embryonic coelom and decomposition of the mid-trunk somites into mesenchyme-like loose tissue. There was, moreover, a considerable increase in cell size, and both the nuclei and the nucleoli in the nervous tissue were enlarged.

Protein synthetic patterns in teratocarcinoma stem cells and mouse embryos at early stages of development

1978 ◽  
Vol 66 (1) ◽  
pp. 8-16 ◽  
Author(s):  
Gail R. Martin ◽  
Sandra Smith ◽  
Charles J. Epstein
Keyword(s):  
Stem Cells ◽  
Mouse Embryos ◽  
Stages Of Development ◽  
Early Stages

FEATURES OF DEVELOPMENT OF THE DIGESTIVE SYSTEM CLARAVIA CATFISH (CLARIIDAE) IN THE EARLY STAGES OF DEVELOPMENT

2017 ◽  
Vol 59 (2) ◽  
pp. 053-063
Author(s):  
Anna V. Pirog ◽  
◽  
Olga V. Lozhnichenko ◽  
Keyword(s):  
Digestive System ◽  
Stages Of Development ◽  
Early Stages

Comparative leaf development of aerial and aquatic growth forms of Myriophyllum aquaticum

Botany ◽  
2013 ◽  
Vol 91 (7) ◽  
pp. 421-430 ◽  
Author(s):  
M.D. Shafiullah ◽  
Christian R. Lacroix
Keyword(s):  
Apical Meristem ◽  
Epidermal Cells ◽  
The Other ◽  
Developmental Study ◽  
Growth Forms ◽  
Myriophyllum Aquaticum ◽  
Stages Of Development ◽  
Qualitative And Quantitative ◽  
Early Stages ◽  
Other Hand

Myriophyllum aquaticum (Vell.) Verdc. produces two morphologically different forms of leaves based on whether they are aerial or aquatic. The objective of this study was to determine whether there are any similarities or differences between these two growth forms during their early stages of development. A comparative developmental study of aerial and aquatic growth forms of M. aquaticum was conducted from a qualitative and quantitative perspective using a scanning electron microscope. The pattern of leaf and lobe initiation such as their origin and shape were similar in both growth forms until the fourth plastochron (stage P4). Differences between the two growth forms became evident from stage P5 onward, where a larger shoot apical meristem (SAM), elongated epidermal cells, shorter and slightly more numerous lobes, as well as the presence of appendage-like structures characterized aquatic growth forms. On the other hand, aerial growth forms had smaller SAM, bulb-like epidermal cells, and longer and slightly less numerous leaf lobes. Significant differences between growth forms were noted for parameters such as volume of SAM, length of terminal, first, and middle lobes, as well as the length from first to last lobes. The volume of the SAM of aquatic shoot tips was always greater than aerial forms. On the other hand, lobes of aerial forms were always longer than the aquatic counterpart during early stages of development. This study on the development of M. aquaticum shows that the aerial and aquatic growth forms diverge from their early stages of development.

XV. On the development of the parasitic isopoda

1878 ◽  
Vol 169 ◽  
pp. 505-521 ◽  
Keyword(s):  
The Body ◽  
The Other ◽  
Stages Of Development ◽  
Early Stages ◽  
Abdominal Appendages ◽  
Pair Of Antennae

The following paper contains an account of observations on the development of the species Cymothoa œstroides and C . parallela of Milne Edwards; but the forms of the young seem to show that several species are really included under these two names. In the early stages of development the only observable difference that exists between the embryos is one of size, but in the later stages they differ very markedly from each other in their external characters. From adult individuals answering the description of C . œstroides I have obtained four varieties of embryos: two with long antennae and two with short.* In the two former the first pair of antennae are but slightly longer than the head, while the second pair are longer than the body; the eyes are small. In one of the varieties thus characterised the abdominal appendages are fringed with long hairs (fig. 20), and in the other they are smooth.

Cell division and cell allocation in early mouse development

Development ◽  
1978 ◽  
Vol 48 (1) ◽  
pp. 37-51
Author(s):  
S. J. Kelly ◽  
J. G. Mulnard ◽  
C. F. Graham
Keyword(s):  
Cell Division ◽  
Tritiated Thymidine ◽  
Mouse Embryos ◽  
Mouse Development ◽  
Stages Of Development ◽  
Cell Stage ◽  
Cell Cycles ◽  
Short Cell ◽  
Early Mouse

Cell division was observed in intact and dissociated mouse embryos between the 2-cell stage and the blastocyst in embryos developing in culture. Division to the 4-cell stage was usually asynchronous. The first cell to divide to the 4-cell stage produced descendants which tended to divide ahead of those cells produced by its slow partner at all subsequent stages of development up to the blastocyte stage. The descendants of the first cell to divide to the 4-cell stage did not subsequently have short cell cycles. The first cell or last cell to divide from the 4-cell stage was labelled with tritiated thymidine. The embryo was reassembled, and it was found that the first pair of cells to reach the 8-cell stage contributed disproportionately more descendants to the ICM when compared with the last cell to divide to the 8-cell stage.

Morphological variations of Phrosina semilunata Risso, 1822 juveniles (Crustacea: Amphipoda: Hyperiidea), new evidence from the Gulf of Mexico

Zootaxa ◽  
2021 ◽  
Vol 4995 (3) ◽  
pp. 594-600
Author(s):  
MARCO VIOLANTE-HUERTA ◽  
LAURA SANVICENTE-AÑORVE ◽  
MARGARITA HERMOSO-SALAZAR ◽  
AURORA MARRÓN-BECERRA
Keyword(s):  
Gulf Of Mexico ◽  
Monotypic Genus ◽  
Stages Of Development ◽  
Morphological Variations ◽  
Stages Of Growth ◽  
Early Stages ◽  
Southern Gulf Of Mexico ◽  
New Evidence ◽  
Lack Of Knowledge

Lack of knowledge of morphological variations during growth of amphipod crustaceans can result in misidentification of species. In this study, we advance the knowledge of morphological variations of juveniles of the monotypic genus Phrosina Risso, 1822 collected in the oceanic province of the southern Gulf of Mexico. The juveniles differed from the adults mainly in the morphology of pereopods 3 & 4 in that the carpal process is parallel to the propodus, also the rami of the pleopoda consist of only four segments, uropoda 3 are more lanceolate, and the uropoda bear a large prominent spine terminally. These morphological variations have not been described for the species previously. Therefore, the current observations enrich the description of P. semilunata in the early stages of growth and support the need for further taxonomical studiest that could help identify species at different stages of development.  

COMPUTER-AIDED DESIGN OF AIRCRAFT AIR-JET ENGINE AT THE EARLY STAGES OF DEVELOPMENT

Vestnik UGATU ◽  
2021 ◽  
Vol 25 (3) ◽  
pp. 18-33
Author(s):  
Alexander Evgenievich Kishalov
Keyword(s):  
Computer Aided Design ◽  
Stages Of Development ◽  
Jet Engine ◽  
Early Stages ◽  
Air Jet ◽  
Computer Aided ◽  
Aided Design

Baby steps: a report exploring the development of neonatal music therapy programmes in Estonia, Greece and Wales

2021 ◽  
Vol 13 (2) ◽  
pp. 132-137
Author(s):  
Elizabeth Coombes ◽  
Marion Musting ◽  
 Ivad Al-Muzzafar ◽  
Christina Kalliodi 
Keyword(s):  
Music Therapy ◽  
Family Members ◽  
European Countries ◽  
Treatment Goals ◽  
Stages Of Development ◽  
Early Stages ◽  
Client Population ◽  
Growing Body ◽  
Therapy Interventions ◽  
Future Growth

There is a growing body of music therapy work addressing the needs of infants born prematurely. This also includes work with parents and other family members during hospitalisation. A variety of music therapy interventions are utilised to support a range of treatment goals for this client population. This report describes and discusses such work that is in the early stages of development in 3 European countries: Estonia, Greece and Wales. The development and content of the interventions in each country is described, with recommendations as to the sustainability and future growth of each programme

Etude expérimentale sur les premiers stades du développement du membre antérieur chez l'embryon du Chélonien Emys orbicularis L.: détermination en mosaïque et régulation

Development ◽  
1977 ◽  
Vol 42 (1) ◽  
pp. 135-148
Author(s):  
J. Vasse
Keyword(s):  
Experimental Study ◽  
Developmental Stage ◽  
Limb Development ◽  
Stages Of Development ◽  
Emys Orbicularis ◽  
Bud Development ◽  
Early Stages ◽  
Regional Determination

Experimental study on the early stages of development of the front limbs of the embryo of the chelonian Emys orbicularis L.: mosaic determination and regulation Ablation of postotic somites 6–13 on one side in embryos of Emys orbicularis L. or injury to the adjacent somatopleure at the developmental stage when 15–21 somite pairs were present, led to arrest of forelimb-bud development in this part of the somatopleure on the operated side. Limb development in the remaining part of prospective somatopleure on the operated side was investigated 5–11 days after the operation. When this part of somatopleure was adjacent to cranial somites 6–9 or 6–10, the development stopped at the start of the apical crest as in Anguis or Scelotes forelimb-buds. A part of somatopleure adjacent to caudal somites 8–12, 9–12 or 10–12 developed into a normal limb with three segments; a part of somatopleure adjacent to 1–2 somites only, developed into a reduced limb, scarcely swelling. Each somitic level developed in relation to its initial regional determination dependent on position in the cephalocaudal axis; to its environment (cranial or caudal bud) and to the quantity of somatopleural material in the bud.

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