scholarly journals Cell scientist to watch – Vivian Li

2021 ◽  
Vol 134 (16) ◽  
Keyword(s):  
Cancer Research ◽  
Mouse Models ◽  
Cell Biology ◽  
Molecular Mechanisms ◽  
Wnt Signalling ◽  
Early Career ◽  
British Society ◽  
Francis Crick ◽  
Primary Focus ◽  
The University

ABSTRACT Vivian Li obtained her PhD from the University of Hong Kong in 2008, where she investigated the molecular mechanisms of human colonic development and tumorigenesis. Funded by a Croucher Foundation Fellowship, she joined the lab of Hans Clevers at the Hubrecht Institute in the Netherlands for her postdoctoral work. There, she identified novel Wnt signalling mechanisms at different subcellular levels and characterised intestinal stem cell genes using newly created transgenic mouse models. Vivian established her group at the MRC National Institute for Medical Research, which is now part of the Francis Crick Institute, London, in February 2013. In her lab she uses genetic mouse models and organoids to investigate the regulation of intestinal homeostasis and cancer with a primary focus on the Wnt signalling pathway. Vivian was awarded a Future Leaders in Cancer Research Prize in 2018 by Cancer Research UK and is the winner of the 2021 Women in Cell Biology Early Career Medal awarded by the British Society for Cell Biology.

scholarly journals Cell scientist to watch – Yanlan Mao

2020 ◽  
Vol 133 (17) ◽  
pp. jcs252569
Keyword(s):  
Cell Biology ◽  
Shape Control ◽  
Cell Signalling ◽  
Tissue Mechanics ◽  
Early Career ◽  
Women In Science ◽  
British Society ◽  
University College London ◽  
Cell Shape Control ◽  
The University

ABSTRACTYanlan Mao graduated in Natural Sciences from the University of Cambridge, UK, followed by a PhD in developmental biology and genetics at the MRC Laboratory of Molecular Biology (MRC-LMB), Cambridge, UK. During this time, she studied cell signalling and epithelial patterning in Drosophila, under the supervision of Matthew Freeman. For her postdoctoral research, Yanlan moved to the Cancer Research UK London Research Institute (now part of the Francis Crick Institute), to study the role of mechanical forces in the orientation of cell division and cell shape control in Nic Tapon's laboratory. She established her own research group in 2014 at the MRC Laboratory for Molecular Cell Biology (MRC-LMCB), University College London, where she addresses the importance of tissue mechanics during development, homeostasis and repair. She was awarded a L'Oreal UNESCO Women in Science Fellowship and the Lister Institute Research Prize in 2018. In 2019, she was awarded the Biophysical Society Early Career Award in Mechanobiology and also became part of the EMBO Young Investigator Programme. Yanlan is the recipient of the 2020 Women in Cell Biology Early Career Award Medal from the British Society for Cell Biology (BSCB).

First person – Fanny Jaudon and Martina Albini

2021 ◽  
Vol 134 (16) ◽  
Keyword(s):  
Neurotrophic Factor ◽  
Neurological Disorders ◽  
Molecular Mechanisms ◽  
Neurological Diseases ◽  
Early Career ◽  
First Person ◽  
Early Career Researchers ◽  
And Function ◽  
The University ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Fanny Jaudon and Martina Albini are co-first authors on ‘ A developmental stage- and Kidins220-dependent switch in astrocyte responsiveness to brain-derived neurotrophic factor’, published in JCS. Fanny is a postdoc at the University of Trieste in the lab of Lorenzo A. Cingolani at Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Genova, Italy, investigating the molecular mechanisms controlling development and function of neuronal circuits and implementing genome-editing approaches for the treatment of neurological disorders. Martina is a PhD student at the Istituto Italiano di Tecnologia in the lab of Fabio Benfenati and Fabrizia Cesca investigating neurotrophin biology and its involvement in neurological diseases.

scholarly journals First person – Elin Schoultz and Ellen Johansson

2021 ◽  
Vol 15 (2) ◽  
Keyword(s):  
Thyroid Gland ◽  
Cell Biology ◽  
Molecular Mechanisms ◽  
Tumor Development ◽  
Neck Region ◽  
Early Career ◽  
Field Cancerization ◽  
First Person ◽  
Head And Neck Region ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career researchers promote themselves alongside their papers. Elin Schoultz and Ellen Johansson are co-first authors on ‘ Tissue architecture delineates field cancerization in BrafV600E-induced tumor development’, published in DMM. Elin is an MD, PhD student in the lab of Mikael Nilsson at Sahlgrenska Centre for Cancer Research, Gothenburg University, Gothenburg. She has a great interest in the thyroid gland in particular, and the mechanisms of tumor development, progression and treatment associated with epithelial carcinomas in general. Ellen is an MD, resident physician in oto-rhino-laryngology and postdoctoral researcher in the lab of Karin Roberg at Department of Biomedical and Clinical Sciences, Division of Cell Biology, Linköping University, Linköping, with broad interest the thyroid gland, tumors of the head and neck region, and the molecular mechanisms that are important for tumor initiation, development, and treatment.

scholarly journals Interview with 2020 Hooke medal winner Ian Chambers

2020 ◽  
Vol 133 (20) ◽  
pp. jcs254219
Keyword(s):  
Stem Cell ◽  
Stem Cell Research ◽  
Cell Biology ◽  
Embryonic Stem ◽  
British Society ◽  
Control Of Gene Expression ◽  
Erythroid Precursor ◽  
Cell Fate Decisions ◽  
University Of Edinburgh ◽  
The University

ABSTRACTIan Chambers studied biochemistry at the University of Strathclyde in Glasgow, UK. He then did his PhD in the laboratory of Paul Harrison at the Beatson Institute for Cancer Research, also in Glasgow. Ian studied the control of gene expression during the differentiation of erythroid precursor cells, discovering that the amino acid selenocysteine is encoded by UGA, which until then was thought to work only as a termination codon. Ian did his post-doctoral work on the regulation of the human immunodeficiency virus (HIV) with Paul Berg at Stanford University in California, USA. In 1991, he returned to Scotland to work on stem cell regulation with Austin Smith at the Centre for Genome Research (later the Institute for Stem Cell Research) at the University of Edinburgh, UK. During that time, Ian identified the transcription factor Nanog, which directs efficient embryonic stem cell self-renewal. Ian started his research group in 2006 at the University of Edinburgh, where he is also a Professor of Pluripotent Stem Cell Biology. His laboratory tries to understand the regulatory networks and transcription factors that control the identity of pluripotent embryonic stem cells, and how these modulate cell fate decisions during the differentiation process. Ian is now the Head of the Institute for Stem Cell Research at University of Edinburgh, an EMBO member and a Fellow of the Royal Society of Edinburgh. Ian is the recipient of the 2020 Hooke Medal from the British Society for Cell Biology (BSCB).

scholarly journals First person – Elliott Bernard

2021 ◽  
Vol 134 (5) ◽  
pp. jcs258535
Keyword(s):  
Cell Biology ◽  
Membrane Dynamics ◽  
Early Career ◽  
First Person ◽  
Early Career Researchers ◽  
Francis Crick ◽  
Complex Membrane ◽  
Human Ipsc ◽  
Selection Of

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Elliott Bernard is first author on ‘M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion’, published in JCS. Elliott is a PhD student in the lab of Maximiliano (Max) Gutierrez at The Francis Crick Institute, London, UK, investigating the cell biology of the endolysosomal and autophagy systems and their dysfunction in disease.

scholarly journals First person – Fumiya Okawa, Yutaro Hama and Sidi Zhang

2021 ◽  
Vol 134 (8) ◽  
Keyword(s):  
Graduate School ◽  
Molecular Mechanisms ◽  
Structure And Function ◽  
Early Career ◽  
First Person ◽  
Early Career Researchers ◽  
School Of Medicine ◽  
And Function ◽  
The University ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Fumiya Okawa, Yutaro Hama and Sidi Zhang are co-first authors on ‘Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1’, published in JCS. Fumiya and Yutaro are PhD students and Sidi is a postdoc in the lab of Noboru Mizushima at the Department of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, Japan, where they are investigating the molecular mechanisms and origin of autophagy.

scholarly journals First person – Anna Dowbaj

2021 ◽  
Vol 134 (13) ◽  
Keyword(s):  
Cell Biology ◽  
Early Career ◽  
First Person ◽  
Max Planck ◽  
Early Career Researchers ◽  
Francis Crick ◽  
Molecular Cell Biology ◽  
Cell Niche ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Anna Dowbaj is co-first author on ‘ An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttling’, published in JCS. Anna conducted the work described in this article while a PhD student in the lab of Erik Sahai at the Francis Crick Institute, London, UK. She is now a postdoc in the lab of Meritxell Huch at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany, investigating the role of the stem cell niche in liver regeneration.

scholarly journals First person – Ines Alvarez Rodrigo

2021 ◽  
Vol 134 (14) ◽  
Keyword(s):  
Wnt Signalling ◽  
Early Career ◽  
First Person ◽  
Early Career Researchers ◽  
Francis Crick ◽  
Microscopy Techniques ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Ines Alvarez Rodrigo is first author on ‘ Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation’, published in JCS. Ines conducted the research described in this article while a PhD student in Jordan Raff's lab at Sir William Dunn School of Pathology, Oxford, UK. She is now a postdoc in the lab of J. P. Vincent at The Francis Crick Institute, London, UK, investigating applying advanced microscopy techniques to study Wnt signalling during development.

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