Effects of Hypothermia and Hyperthermia on Fertilization in Rat Eggs

1956 ◽  
Vol 33 (2) ◽  
pp. 348-357
Author(s):  
C. R. AUSTIN

The chilling of rats to body temperatures down to 4-7° C. before and during the time of ovulation had little effect upon the subsequent penetration of the eggs by spermatozoa. With a hypothermia of 0-1° C, however, there was almost complete and apparently permanent inhibition of spermatozoon entry. There seemed to be no reason to ascribe this effect to direct influence of cold on eggs or spermatozoa. Probably the failure of penetration arose largely from delay of ovulation, coupled perhaps with some derangement of the tubal environment. Hypothermia after ovulation but before and during the time of spermatozoon entry into the eggs temporarily but completely inhibited penetration when the body temperature was kept below 33° C. The likely explanation appears to be that ‘capacitation’ is prevented or greatly slowed by such temperatures. Hyperthermia, induced before and during the time of ovulation, somewhat reduced the mean number of eggs ovulated (from 10.5 to 7.5) and the proportion penetrated by spermatozoa (from 97 to 66%). The proportion of eggs penetrated by two or more spermatozoa was increased (from 19 to 28%), but the frequency of polyspermic fertilization did not change significantly. Hyperthermia after ovulation but before and during the time of spermatozoon entry also led to a greater proportion of eggs containing two or more spermatozoa (31%), but in addition it increased the incidence of polyspermy (from 2.5 to21.2%). Larger rats (170-200 g.) subjected to hyperthermia showed a higher frequency of polyspermy (34%) than smaller rats (100-130 g.; 13% polyspermy). Evidently the processes involved in the ‘zona reaction’ are reduced in efficiency by hyperthermia whether applied before or after ovulation. On the other hand, the block to polyspermy depends on processes that are much more sensitive to heat after ovulation. It is considered that the slowing down of the block to polyspermy is associated with ageing of the egg, that the ageing is accelerated by hyperthermia and that this effect is promoted in older rats.

1960 ◽  
Vol 11 (5) ◽  
pp. 871 ◽  
Author(s):  
DF Dowling

An experiment was performed to test the effect of solar radiation on the body temperatures of cattle, both clipped and with hair coat, in a clear transparent plastic covering as compared with cattle in a white reflective plastic covering. The mean body temperature of the animals in white plastic coats was 0.15°F lower than that of animals in clear plastic coats. This difference was highly significant statistically (P< 0.001). Animals in both clear and white coats had higher body temperatures than controls without plastic coats. The difference was highly significant, and was about 1.5°F in the clipped animals.


1958 ◽  
Vol 193 (3) ◽  
pp. 539-540 ◽  
Author(s):  
A. H. Hamdy ◽  
C. R. Weaver

The body temperatures of 37 Merino and Shropshire lambs were recorded for the first 100 days of life. Mean temperature of Merino lambs was found to be 102.8°F with a range of 100.2°– 104.0°F while the mean temperature of Shropshire lambs was 102.7°F with a range of 101.2°–104.4°F. There was no relation between the internal and atmospheric temperatures. Again, the correlation between the body and atmospheric temperatures within limited age groups was not statistically significant. The temperature of older lambs was less variable than that of younger lambs.


Author(s):  
Sunandar Macpal ◽  
Fathianabilla Azhar

The aims of this paper is to explain the use of high heels as an agency for a woman's body. Agency context refers to pain in the body but pain is perceived as something positive. In this paper, the method used is a literature review by reviewing writings related to the use of high heels. The findings in this paper that women experience body image disturbance or anxiety because they feel themselves are not beautiful or not attractive. The use of high heels, makes women more attractive and more confident, on the other hand the use of high heels actually makes women feel pain and discomfort. However, for the achievement of beauty standards, women voluntarily allow their bodies to experience pain. However, the agency's willingness to beauty standards here is meaningless without filtering and directly accepted. Instead women keep negotiating with themselves so as to make a decision why use high heels.


Author(s):  
Zoran Vrucinic

The future of medicine belongs to immunology and alergology. I tried to not be too wide in description, but on the other hand to mention the most important concepts of alergology to make access to these diseases more understandable, logical and more useful for our patients, that without complex pathophysiology and mechanism of immune reaction,we gain some basic insight into immunological principles. The name allergy to medicine was introduced by Pirquet in 1906, and is of Greek origin (allos-other + ergon-act; different reaction), essentially representing the reaction of an organism to a substance that has already been in contact with it, and manifested as a specific response thatmanifests as either a heightened reaction, a hypersensitivity, or as a reduced reaction immunity. Synonyms for hypersensitivity are: altered reactivity, reaction, hypersensitivity. The word sensitization comes from the Latin (sensibilitas, atis, f.), which means sensibility,sensitivity, and has retained that meaning in medical vocabulary, while in immunology and allergology this term implies the creation of hypersensitivity to an antigen. Antigen comes from the Greek words, anti-anti + genos-genus, the opposite, anti-substance substance that causes the body to produce antibodies.


Religions ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 380
Author(s):  
Matthew John Paul Tan

This paper will focus on one element of the pushback against the massive influx of immigrants taken in for humanitarian purposes, namely, an identity-based chauvinism which uses identity as the point of resistance to the perceived dilution of that identity, brought about by the transformation of culture induced by the incorporation of a foreign other. The solution to this perceived dilution is a simultaneous defence of that culture and a demand for a conformity to it. While those in the critical tradition have encouraged a counter-position of revolutionary transformation by the other through ethics, dialogue, or the multitude, such a transformation is arguably impeded by what is ultimately a repetition of the metaphysics of conformity. Drawing on the personalism of Emmanuel Mounier and the Eucharistic theology of Creston Davis and Aaron Riches, this paper submits an alternative identity politics position that completes the revolutionary impulse. Identity here is not the flashpoint of a self-serving conflict, but the launch-point of politics of self-emptying, whose hallmarks include, on the one hand, a never-ending reception of transformation by the other, and on the other hand, an anchoring in the Body of Christ that is at once ever-changing and never-changing.


2000 ◽  
pp. 472-476 ◽  
Author(s):  
NA Huizenga ◽  
WW De Herder ◽  
JW Koper ◽  
P de Lange ◽  
D AJ v Lely ◽  
...  

OBJECTIVE: Glucocorticoids (GCs) serve a variety of important functions throughout the body. The synthesis and secretion of GCs are under the strict influence of the hypothalamo-pituitary-adrenal axis. The mechanisms of action of GCs are mediated by the intracellular glucocorticoid receptor (GR). Over the years, many studies have been performed concerning the regulation of GR expression by GC concentrations. METHODS: In the present study, we determined the characteristics of the GR in peripheral mononuclear blood leukocytes (PBML) from thirteen patients with endogenous Cushing's syndrome and fifteen control subjects, using a whole cell dexamethasone binding assay. Furthermore, cortisol concentrations were determined in order to investigate a possible relationship between serum cortisol levels and receptor characteristics. RESULTS: There were no differences in mean receptor number between patients and controls. On the other hand, a significantly lower ligand affinity was identified in cells from patients with Cushing's syndrome compared with controls. A complete normalisation of the ligand affinity was observed after treatment in the only patient tested in this respect, whereas the receptor number was not affected. In patients, there was a statistically significant negative correlation between cortisol concentrations and ligand affinity, which was not found in controls. CONCLUSION: Receptor down-regulation does not occur in PBML from patients with endogenous Cushing's syndrome. On the other hand, there seems to be a diminished ligand affinity which possibly reflects receptor modification in response to exposure to the continuously high cortisol levels in patients with Cushing's syndrome. This assumption is substantiated by the fact that in one patient a normalisation of the ligand affinity after complete remission of the disease was seen.


2012 ◽  
Vol 602-604 ◽  
pp. 776-780
Author(s):  
Zhi Qiang Li ◽  
Mei Li ◽  
Wei Jia Fan

Poly(3-hydroxybutyrate-co-4-hydroxybutyrate)copolymer [P(3HB-co-4HB)] is a kind of biodegradable high molecular polymer produced by bioaccumulation. Because of the good biodegradability and biocompatibility, P(3HB-co-4HB)s have attracted wide attention . At first, the intrinsic viscosity[η] in good solvent of P(3HB-co-4HB) s with varying contents of 4HB was investigated in different temperature. Second, observed the changes of crystallization gathered state caused by the varying contents of 4HB by polarizing microscope. The results show that to the P(3HB-co-4HB)s in same molecular weight, the intrinsic viscosity[η] in good solvent barely changes when the mole fractions of 4HB increase. On the other hand, the mean square end to end distances[0] of macromolecular flexible chains increase with the mole fractions of 4HB. At the same time, the states of aggregation change from spherulites to dendrites. In this investigation, we discuss the reasons of the differences in depth.


1980 ◽  
Vol 84 (1) ◽  
pp. 119-136
Author(s):  
D. Mellon ◽  
J. E. Treherne ◽  
N. J. Lane ◽  
J. B. Harrison ◽  
C. K. Langley

Intracellular recordings demonstrated a transfer of impulses between the paired giant axons of Sabella, apparently along narrow axonal processes contained within the paired commissures which link the nerve cords in each segment of the body. This transfer appears not to be achieved by chemical transmission, as has been previously supposed. This is indicated by the spread of depolarizing and hyperpolarizing voltage changes between the giant axons, the lack of effects of changes in the concentrations of external divalent cations on impulse transmission and by the effects of hyperpolarization in reducing the amplitude of the depolarizing potential which precedes the action potentials in the follower axon. The ten-to-one attenuation of electronic potentials between the giant axons argues against the possibility of an exclusively passive spread of potential along the axonal processes which link the axons. Observation of impulse traffic within the nerve cord commissures indicates, on the other hand, that transmission is achieved by conduction of action potentials along the axonal processes which link the giant axons. At least four pairs of intact commissures are necessary for inter-axonal transmission, the overall density of current injected at multiple sites on the follower axon being, it is presumed, sufficient to overcome the reduction in safety factor imposed by the geometry of the system in the region where axonal processes join the giant axons. The segmental transmission between the giant axons ensures effective synchronization of impulse traffic initiated in any region of the body and, thus, co-ordination of muscular contraction, during rapid withdrawal responses of the worm.


2020 ◽  
Vol 7 (2) ◽  
pp. 411-430
Author(s):  
Maja Tabea Jerrentrup

Abstract The art of bodypainting that is fairly unknown to a wider public turns the body into a canvas - it is a frequently used phrase in the field of bodypainting that illustrates the challenge it faces: it uses a three-dimensional surface and has to cope with its irregularities, but also with the model’s abilities and characteristics. This paper looks at individuals who are turned into art by bodypainting. Although body painting can be very challenging for them - they have to expose their bodies and to stand still for a long time while getting transformed - models report that they enjoy both the process and the result, even if they are not confident about their own bodies. Among the reasons there are physical aspects like the sensual enjoyment, but also the feeling of being part of something artistic. This is enhanced and preserved through double staging - becoming a threedimentional work of art and then being staged for photography or film clips. This process gives the model the chance to experience their own body in a detached way. On the one hand, bodypainting closely relates to the body and on the other hand, it can help to over-come the body.


2021 ◽  
Vol 5 (3) ◽  
pp. 543-549
Author(s):  
Helmy Yudhistira Putra ◽  
Utomo Budiyanto

During the COVID-19 pandemic, the price of preventive equipment such as masks and hand sanitizers has increased significantly. Likewise, thermometers are experiencing an increase and scarcity, this tool is also sought after by many companies for screening employees and guests before entering the building to detect body temperatures that are suspected of being positive for COVID-19. The use of a thermometer operated by humans is very risky because dealing directly with people who could be ODP (People Under Monitoring/Suscpected ) or even positive for COVID-19, therefore we need tools for automatic body temperature screening and do not involve humans for the examination. This research uses the MLX-90614 body temperature sensor equipped with an ultrasonic support sensor to detect movement and measure the distance between the forehead and the temperature sensor so that the body heat measurement works optimally, and a 16x2 LCD to display the temperature measurement results. If the measured body temperature is more than 37.5 ° C degrees Celsius then the buzzer will turn on and the selenoid door lock will not open and will send a notification to the Telegram messaging application. The final result obtained is the formation of a prototype device for measuring body temperature automatically without the need to involve humans in measuring body temperature to control people who want to enter the building so as to reduce the risk of COVID-19 transmission


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