Hiv-Related Psychological Disturbances Improve After Six Weeks Of Moderate Intensity Exercise Training

2011 ◽  
Vol 43 (Suppl 1) ◽  
pp. 22
Author(s):  
Jason R. Jaggers ◽  
Wesley D. Dudgeon ◽  
Kenneth D. Phillips ◽  
Stephanie Burgess ◽  
J. Larry Durstine ◽  
...  
Keyword(s):  
Exercise Training ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Psychological Disturbances

Eight weeks of moderate-intensity exercise training increases heart rate variability in sedentary postmenopausal women

2004 ◽  
Vol 147 (5) ◽  
pp. e8-e15 ◽  
Author(s):  
Radim Jurca ◽  
Timothy S Church ◽  
Gina M Morss ◽  
Alexander N Jordan ◽  
Conrad P Earnest
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Exercise Training ◽  
Postmenopausal Women ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise

scholarly journals The Preventive Role of Regular Physical Training in Ventricular Remodeling, Serum Cardiac Markers, and Exercise Performance Changes in Breast Cancer in Women Undergoing Trastuzumab Therapy—An REH-HER Study

2020 ◽  
Vol 9 (5) ◽  
pp. 1379
Author(s):  
Katarzyna Hojan ◽  
Danuta Procyk ◽  
Dorota Horyńska-Kęstowicz ◽  
Ewa Leporowska ◽  
Maria Litwiniuk
Keyword(s):  
Breast Cancer ◽  
Exercise Training ◽  
Exercise Performance ◽  
Physical Training ◽  
Ventricular Remodeling ◽  
Protective Measure ◽  
Moderate Intensity ◽  
Cardiac Markers ◽  
Moderate Intensity Exercise ◽  
Trastuzumab Therapy

Cardiotoxicity is known as a severe clinical problem in oncological practice that reduces the options for cancer therapy. Physical exercise is recognized as a well-established protective measure for many heart and cancer diseases. In our study, we hypothesized that supervised and moderate-intensity exercise training would prevent heart failure and its consequences induced by trastuzumab therapy. The aim of this study was to examine the effect of physical training on ventricular remodeling, serum cardiac markers, and exercise performance in women with human epidermal growth receptor 2 (HER2+) breast cancer (BC) undergoing trastuzumab therapy. This was a prospective, randomized, clinical controlled trial. Forty-six BC women were randomized into either an intervention group (IG) or a control group (CG). An exercise program (IG) was performed after 3–6 months of trastuzumab therapy at 5 d/week (to 80% maximum heart rate (HRmax)) for 9 weeks. We then evaluated their cardiac function using echocardiography, a 6-Minute Walk Test (6MWT), and plasma parameters (C-reactive protein (CRP), myoglobin (MYO), interleukin-6 (IL-6), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and creatine kinase (CK)). After the physical training program, we did not observe any significant changes in the left ventricular (LV) ejection fraction (LVEF) and 6MWT (p > 0.05) in the IG compared to the CG (decrease p < 0.05). The differences in the blood parameters were not significant (p < 0.05). To conclude, moderate-intensity exercise training prevented a decrease in the LVEF and physical capacity during trastuzumab therapy in HER2+ BC. Further research is needed to validate our results.

Heart rate response to exercise and cardiorespiratory fitness of young women at high familial risk for hypertension: effects of interval vs continuous training

2011 ◽  
Vol 18 (6) ◽  
pp. 824-830 ◽  
Author(s):  
Emmanuel G Ciolac ◽  
Edimar A Bocchi ◽  
Julia MD Greve ◽  
Guilherme V Guimarães
Keyword(s):  
Heart Rate ◽  
Exercise Training ◽  
Cardiorespiratory Fitness ◽  
Familial Risk ◽  
Moderate Intensity ◽  
Hypertensive Disorder ◽  
Moderate Intensity Exercise ◽  
Continuous Training ◽  
Response To Exercise

Exercise training is an effective intervention for treating and preventing hypertension, but its effects on heart rate (HR) response to exercise and cardiorespiratory fitness (CRF) of non-hypertensive offspring of hypertensive parents (FH+) has not been studied. We compared the effects of three times per week equal-volume high-intensity aerobic interval (AIT) and continuous moderate-intensity exercise (CME) on HR response to exercise and CRF of FH+. Forty-four young FH+ women (25.0 ± 4.4 years) randomized to control (CON; n = 12), AIT (80–90% of VO2MAX; n = 16), or CME (50–60% of VO2MAX; n = 16) performed a graded exercise test (GXT) before and after 16 weeks of follow-up to evaluate HR response to exercise and several parameters of CRF. Resting, maximal, and reserve HR did not change after the follow-up in all groups. HR recovery (difference between HRMAX and HR at 1 minute of GXT recovery phase) improved only after AIT (11.8 ± 4.9 vs. 20.6 ± 5.8 bpm, p < 0.01). Both exercise programmes were effective for improving CRF parameters, but AIT was more effective than CME for improving oxygen consumption at the respiratory compensation point (VO2RCP; 22.1% vs. 8.8%, p = 0.008) and maximal effort (VO2MAX; 15.8% vs. 8.0%, p = 0.036), as well as tolerance time (TT) to reach anaerobic threshold (TTAT; 62.0 vs. 37.7, p = 0.048), TTRCP (49.3 vs. 32.9, p = 0.032), and TTMAX (38.9 vs. 29.2, p = 0.042). Exercise intensity was an important factor in improving HR recovery and CRF of FH+women. These findings may have important implications for designing exercise-training programmes for the prevention of an inherited hypertensive disorder.

scholarly journals Effect of Moderate-Intensity Exercise Training on Peak Oxygen Consumption in Patients With Hypertrophic Cardiomyopathy

JAMA ◽  
2017 ◽  
Vol 317 (13) ◽  
pp. 1349 ◽  
Author(s):  
Sara Saberi ◽  
Matthew Wheeler ◽  
Jennifer Bragg-Gresham ◽  
Whitney Hornsby ◽  
Prachi P. Agarwal ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Hypertrophic Cardiomyopathy ◽  
Exercise Training ◽  
Peak Oxygen Consumption ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise

Lean Tissue Mass And Fat Mass Changes In HIV-infected Persons Following Moderate Intensity Exercise Training

2005 ◽  
Vol 37 (Supplement) ◽  
pp. S127
Author(s):  
Wesley D. Dudgeon ◽  
Kenneth D. Phillips ◽  
Stephanie E. Burgess ◽  
J. Larry Durstine ◽  
Gregory A. Hand
Keyword(s):  
Exercise Training ◽  
Fat Mass ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Lean Tissue ◽  
Tissue Mass ◽  
Lean Tissue Mass

Exercise restores bioavailability of hydrogen sulfide and promotes autophagy influx in livers of mice fed with high-fat diet

2017 ◽  
Vol 95 (6) ◽  
pp. 667-674 ◽  
Author(s):  
Bing Wang ◽  
Jing Zeng ◽  
Qi Gu
Keyword(s):  
Hydrogen Sulfide ◽  
Exercise Training ◽  
High Fat Diet ◽  
Mass Gain ◽  
Moderate Intensity ◽  
High Fat ◽  
Moderate Intensity Exercise ◽  
Nonalcoholic Fatty Liver ◽  
Mercaptopyruvate Sulfurtransferase ◽  
Underlying Mechanisms

In the gold standard treatment for nonalcoholic fatty liver disease (NAFLD), exercise training has been shown to effectively improve nonalcoholic steatohepatitis (NASH). However, limited data are available about the underlying mechanisms involved. This work was undertaken to investigate the mechanisms underlying the beneficial effect of exercise training on high-fat diet (HFD)-induced NAFLD in mice. Male mice were fed with HFD and given moderate-intensity exercise for 24 weeks. Exercise training lowered mass gain, attenuated systemic insulin resistance and glucose intolerance, and mitigated hepatic steatosis and fibrosis in mice fed with HFD. Exercise training improved mitochondrial function and enhanced mitochondrial β-oxidation in livers of HFD-fed mice. Exercise training enhanced hydrogen sulfide (H2S) levels in plasma and livers, and mRNA expression of cystathionine β-synthase (CBS), cystathionine γ-lyase (CES), and 3-mercaptopyruvate sulfurtransferase (3-MST) in livers of HFD-fed mice. Exercise training had no significant effect on the ratio of LC3-II/LC3-I, but decreased p62 protein expression in livers of HFD-fed mice. Additionally, exercise training reduced formation of malondialdehyde, enhanced ratio of GSH/GSSG, and down-regulated expression of TNF-α and IL-6 in livers of HFD-fed mice. Exercise training restored bioavailability of H2S and promoted autophagy influx in livers, which might contribute to its benefit on HFD-induced NAFLD.

scholarly journals The effect of moderate versus high intensity exercise on heart rate variability in sedentary office workers

2021 ◽  
Vol 16 (1) ◽  
pp. 16-23
Author(s):  
Vibha Gangwar ◽  
Manish Kumar Verma ◽  
Ritesh Singh Gangwar ◽  
Nitin Ashok John ◽  
Rajani Bala Jasrotia
Keyword(s):  
Heart Rate ◽  
Exercise Training ◽  
High Intensity ◽  
High Intensity Exercise ◽  
Office Workers ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Group I ◽  
Before And After ◽  
Group Ii

Background: Sedentary behavior is one of the leading modifiable risk factors for cardiovascular disease and all-cause mortality. Physical exercise exerts beneficial physiological effects on cardiovascular fitness. Different grades of physical exercise have different effects on cardiovascular health. Objective: To compare the effect of moderate and high intensity exercise training on heart rate variability (HRV) in sedentary office workers. Methods: This study was conducted on 40 healthy sedentary volunteers aged between 20-40 years of both the genders. Participants were distributed into two groups of 20 subjects each. Subjects of group I and group II performed moderate intensity and high intensity exercise respectively on bicycle ergometer for 12 weeks. Their 5- minute ECG recording was done by three channel physiograph, and frequency domain indices of HRV and heart rate (HR) were analyzed and compared before and after exercise training. Their blood pressure was also recorded and compared before and after exercise training. Independent sample t-test and paired sample ttest were used for statistical analysis. Results: HF, systolic and diastolic blood pressure reduced significantly after exercise in group II (p=0.015, 0.005, and 0.015 respectively) while HR and LF/HF ratio reduced in both group I and group II (p=0.000 for HR, and 0.034, 0.001 for LF/HF). The decrease in HR was greater after high intensity exercise than moderate intensity exercise (p= 0.025). Conclusion: Parasympathetic activity improves after moderate and high intensity exercise but improvement is more after high intensity exercise training. Therefore, high intensity exercise training is more beneficial than moderate intensity exercise training. J Bngladesh Soc Physiol 2021;16(1): 16-23

Moderate-intensity Exercise Training in Sole and Simultaneous Forms with Insulin Ameliorates the Experimental Type 1 Diabetes-induced Intrinsic Apoptosis in Testicular Tissue

2019 ◽  
Vol 40 (14) ◽  
pp. 909-920 ◽  
Author(s):  
Zahra Samadian ◽  
Javad Tolouei Azar ◽  
Sana Moshari ◽  
Mazdak Razi ◽  
Asghar Tofighi
Keyword(s):  
Type 1 Diabetes ◽  
Exercise Training ◽  
Caspase 3 ◽  
Moderate Intensity ◽  
Tunel Staining ◽  
Intrinsic Apoptosis ◽  
Moderate Intensity Exercise ◽  
Experimental Type ◽  
Induced Apoptosis

AbstractThe aim of this study was to investigate the ameliorative effect of moderate-intensity exercise training in sole and simultaneous forms with insulin on experimental type 1 diabetes (T1D)-induced apoptosis. A total of 36 mature male Wistar rats were divided into six equally sized groups, including sedentary control (Con), moderate-intensity exercise training (E-sole), sedentary T1D-induced (D-sole), moderate-exercise-trained T1D-induced (DE), insulin-treated sedentary T1D-induced (DI) and exercise-trained, and insulin-treated T1D-induced (DEI) groups. The 6-week exercise training intervention was involved 30 min of moderate-intensity running on a treadmill once daily (5 days/week). Next, tubular differentiation (TDI) and spermiogenesis (SPI) indices were assessed. The Bcl-2, Bax and caspase-3 expressions were determined using RT-PCR, immunohistochemistry and western blot techniques. Finally, the TUNEL staining was used to analyze the apoptosis ratio. The moderate-intensity exercise training in the sole and when simultaneously considered with insulin (DEI) maintained testicular cellularity, up-regulated Bcl-2 expression, reduced Bax expression and ameliorated the diabetes-induced apoptosis. We failed to show remarkable alterations in caspase-3 mRNA and protein levels in the DE group versus D-sole animals. In conclusion, the moderate-intensity exercise training is able to potentially protect testicular cells from T1D-induced intrinsic apoptosis via up-regulating Bcl-2 and downregulating Bax expressions. Moreover, it amplifies the insulin-induced anti-apoptotic impacts.

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