scholarly journals Exercise Training Improves High Blood Pressure Variability-induced Cardiac Damage In Normotensive Rats

2020 ◽  
Vol 52 (7S) ◽  
pp. 561-561
Author(s):  
Ivana C. Moraes-Silva ◽  
Katia De Angelis ◽  
Nilsa R. Damaceno-Rodrigues ◽  
Elia G. Caldini ◽  
Maria Claudia Irigoyen
Keyword(s):  
Blood Pressure ◽  
Exercise Training ◽  
High Blood Pressure ◽  
Blood Pressure Variability ◽  
Cardiac Damage

Effects of 12 weeks of aerobic versus combined aerobic plus resistance exercise training on short-term blood pressure variability in patients with hypertension

2021 ◽  
Vol 130 (4) ◽  
pp. 1085-1092
Author(s):  
Giuseppe Caminiti ◽  
Ferdinando Iellamo ◽  
Annalisa Mancuso ◽  
Anna Cerrito ◽  
Matteo Montano ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Aerobic Exercise ◽  
Blood Pressure Variability ◽  
Short Term ◽  
Resistance Exercise Training ◽  
Hypertensive Patients ◽  
Combined Exercise ◽  
Resistance Exercises

Combined exercise training (CT) including aerobic plus resistance exercises could be more effective in comparison with aerobic exercise (AT) alone in reducing blood pressure variability (BPV) in hypertensive patients. We report that CT was indeed more effective than AT in reducing short-term BPV, and both exercise modalities reduced BP levels to the same extent. CT appears to be a more appropriate exercise modality if the objective is to reduce BPV in addition to BP levels.

High blood pressure variability predicts 30-day mortality but not 1-year mortality in hospitalized elderly patients

2017 ◽  
Vol 26 (5) ◽  
pp. 259-263 ◽  
Author(s):  
Avraham Weiss ◽  
Yaron Rudman ◽  
Yichayaou Beloosesky ◽  
Amit Akirov ◽  
Tzippy Shochat ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Elderly Patients ◽  
High Blood Pressure ◽  
Blood Pressure Variability ◽  
Hospitalized Elderly ◽  
Hospitalized Elderly Patients

Ambulatory blood pressure variability and combined exercise training: comparison between hypertensive and normotensive postmenopausal women

2020 ◽  
Vol 25 (6) ◽  
pp. 338-345
Author(s):  
Igor Moraes Mariano ◽  
Juliene Gonçalves Costa Dechichi ◽  
Larissa Aparecida Santos Matias ◽  
Mateus de Lima Rodrigues ◽  
Jaqueline Pontes Batista ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Exercise Training ◽  
Postmenopausal Women ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Variability ◽  
Combined Exercise ◽  
Combined Exercise Training

scholarly journals School-based surveillance on visit-to-visit blood pressure variability and high blood pressure in children and adolescents

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jiaxiang Wang ◽  
Hui Shen ◽  
Jieyu Liu ◽  
Chengqi Xiao ◽  
Cailong Chen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Children And Adolescents ◽  
High Blood Pressure ◽  
Blood Pressure Variability ◽  
Pediatric Population ◽  
Health Promotion Program ◽  
Logistic Regression Models ◽  
School Based ◽  
Z Scores ◽  
Average Real Variability

Abstract Background The predictive importance of visit-to-visit blood pressure variability (VVV) for high blood pressure (HBP) in a pediatric population has been largely unsettled. We aimed to evaluate it based on Health Promotion Program for Children and Adolescents (HPPCA), a school-based surveillance conducted from 2012 to 2018 in Suzhou, China. Methods A total of 330,618 participants had BP measurement in 2018 and ≥ 3 BP records during 2012–2017, were recruited from HPPCA. Absolute BP values (in mmHg) were converted into age-, sex- and height- normalized z-scores. VVV was expressed as standard deviation (SD), coefficient of variation (CV) or average real variability (ARV) of BP z-scores during 2012–2017. Logistic regression models were used to assess the associations between VVV and HBP in 2018. Results In 2018, 42,554 (12.87%) subjects were defined as HBP. VVV, except for SBP-CV and DBP-CV, was significantly higher in the HBP group than normotensives group. After adjusting for covariates including mean BP values from 2012 to 2017, SBP-SD, SBP-ARV, DBP-SD and DBP-ARV, increased the risk of HBP by 5.70 [95% confidence interval (95% CI) 5.54–5.87], 4.10 (95% CI 4.01–4.20), 4.70 (95% CI 4.50–4.90) and 3.39 (95% CI 3.28–3.50) times, respectively. Notably, SBP-SD significantly improved risk discrimination of HBP based on other risk variables (c-statistics, net reclassification index and integrated discrimination improvement significantly increased). Conclusions Higher SD or ARV of BP, was independently related with higher probability of HBP in Chinese pediatric population. SBP-SD could be potentially helpful for detecting HBP. Future researches investigating the predictive value of VVV are warrant.

Mechanisms of blood pressure variability-induced cardiac hypertrophy and dysfunction in mice with impaired baroreflex

2005 ◽  
Vol 288 (3) ◽  
pp. R767-R776 ◽  
Author(s):  
Peter Martinka ◽  
Jens Fielitz ◽  
Andreas Patzak ◽  
Vera Regitz-Zagrosek ◽  
Pontus B. Persson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiac Hypertrophy ◽  
Protein Content ◽  
High Blood Pressure ◽  
Blood Pressure Variability ◽  
Transforming Growth Factor ◽  
Renin Angiotensin System ◽  
Left Ventricular ◽  
Mitogen Activated Protein Kinase ◽  
Cross Sectional

Enhanced blood pressure variability contributes to left ventricular hypertrophy and end-organ damage, even in the absence of hypertension. We hypothesized that the greater number of high-blood pressure episodes associated with enhanced blood pressure variability causes cardiac hypertrophy and dysfunction by activation of mechanosensitive and autocrine pathways. Normotensive mice were subjected to sinoaortic baroreceptor denervation (SAD) or sham surgery. Twelve weeks later, blood pressure variability was doubled in SAD compared with sham-operated mice. Blood pressure did not differ. Cardiac hypertrophy was reflected in greater heart/body weight ratios, larger myocyte cross-sectional areas, and greater left ventricular collagen deposition. Furthermore, left ventricular atrial and brain natriuretic peptide mRNA expression was greater in SAD than in sham-operated mice. SAD had higher left ventricular end-diastolic pressures and lower myocardial contractility indexes, indicating cardiac dysfunction. Cardiac protein content of phosphorylated p125 focal adhesion kinase (p125 FAK) and phosphorylated p38 mitogen-activated protein kinase (p38 MAPK) was greater in SAD than in sham-operated mice, indicating activation of mechanosensitive pathways of cardiac hypertrophy. Furthermore, enhanced cardiac renin and transforming growth factor-β1 (TGFbeta1) protein content indicates activation of autocrine pathways of cardiac hypertrophy. Adrenal tyrosine hydroxylase protein content and the number of renin-positive glomeruli were not different, suggesting that sympathetic activation and the systemic renin-angiotensin system did not contribute to cardiac hypertrophy. In conclusion, more frequent blood pressure rises in subjects with high blood pressure variability activate mechanosensitive and autocrine pathways leading to cardiac hypertrophy and dysfunction even in the absence of hypertension.

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