scholarly journals Reliability Of Cycle-ergometer Based Cardiopulmonary Exercise Testing In Older Adults With Mild Alzheimer’s Dementia

2021 ◽  
Vol 53 (8S) ◽  
pp. 439-439
Author(s):  
Russell Spafford ◽  
Dereck Salisbury ◽  
Fang Yu
2020 ◽  
Vol 28 (6) ◽  
pp. 911-919
Author(s):  
Dereck L. Salisbury ◽  
Fang Yu

The purpose of this study was to investigate the relationships among peak exercise parameters on 6-min walk test, shuttle walk test, and laboratory-based cardiopulmonary exercise testing in persons with Alzheimer’s dementia. This study is a cross-sectional analysis of the baseline data of 90 participants (age 77.1 [6.6] years, 43% female) from the FIT-AD trial. Cardiopulmonary exercise testing produced significantly higher peak heart rate (118.6 [17.5] vs. 106 [22.8] vs. 106 [18.8] beats/min), rating of perceived exertion (16 [2.1] vs. 12 [2.3] vs. 11 [2.1]), and systolic blood pressure (182 [23.7] vs. 156 [18.9] vs. 150 [16.9] mmHg) compared with the shuttle walk test and 6-min walk test, respectively. Peak walking distance on shuttle walk test (241.3 [127.3] m) and 6-min walk test (365.0 [107.9] m) significantly correlated with peak oxygen consumption (17.1 [4.3] ml·kg−1·min−1) on cardiopulmonary exercise testing (r = .449, p ≤ .001 and r = .435, p ≤ .001), respectively, which is considerably lower than what is seen in older adults and persons with cardiopulmonary diseases.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S611-S611
Author(s):  
Dereck L Salisbury ◽  
Fang Yu

Abstract The purpose of this study was to investigate relationships among peak exercise parameters on 6-minute walk (6MWT) and shuttle walk tests (SWT), and laboratory-based cardiopulmonary exercise testing (CPET). These relationships have been established in cardiopulmonary patient populations, but not in community-dwelling older adults with mild-moderate Alzheimer’s dementia (AD). This study is a cross-sectional analysis of the baseline data of 6MWT, SWT, and CPET from the FIT-AD Trial (n=88: 49 males [76.6 {7.0} years and MMSE 21.5{3.5}] and 39 females [77.3 {6.5} years and MMSE 22.1 {3.4}]). Peak values for each test included heart rate (HR), systolic blood pressure (SBP), and rating of perceived exertion (RPE). Peak oxygen assumption (VO2) was measured in the CPET. Peak walking distance (PWD) was measured for the 6MWT and SWT. CPET produced significantly higher peak HR (118.7 [17.5] vs. 106 [22.8] vs. 106 [18.8] bpm), RPE (16 [2.1] vs. 12 [2.3] vs. 11 [2.1]) and SBP (182 [23.7] vs. 156 [18.9] vs. 150 [16.9] mmHg) compared to the SWT and 6MWT respectively. PWD on SWT (240.4 [128.1] m) and 6MWT (364.3 [108.5] m) significantly correlated with peak VO2 (17.0 [4.3]ml/kg/min) on CPET (r=.44 and r=.43) respectively. Correlations of peak VO2 and PWD on SWT in persons with AD are considerably lower than what is seen for persons with cardiopulmonary diseases. This lower correlation seen in our sample may be due to shorter PWD on walking tests. Future research should focus how mobility affects correlation of peak values on these tests.


Author(s):  
Reza Mazaheri ◽  
Mohammad Sadeghian ◽  
Mahshid Nazarieh ◽  
David Niederseer ◽  
Christian Schmied

Background: Peak oxygen consumption (VO2) measured by cardiopulmonary exercise testing (CPET) is a significant predictor of mortality and future transplantation in heart failure patients with severely reduced ejection fraction (HFrEF). The present study evaluated the differences in peak VO2 and other prognostic variables between treadmill and cycle CPETs in these patients. Methods: In this cross-over study design, thirty males with severe HFrEF underwent CPET on both a treadmill and a cycle ergometer within 2–5 days apart, and important CPET parameters between two exercise test modalities were compared. Results: Peak VO2 was 23.12% higher on the treadmill than on cycle (20.55 ± 3.3 vs. 16.69 ± 3.01, p < 0.001, respectively). Minute ventilation to carbon dioxide production (VE/VCO2) slope was not different between the two CPET modes (p = 0.32). There was a strong positive correlation between the VE/VCO2 slopes during treadmill and cycle testing (r = 0.79; p < 0.001). VE/VCO2 slope was not related to peak respiratory exchange ratio (RER) in either modality (treadmill, r = 0.13, p = 0.48; cycle, r = 0.25, p = 0.17). The RER level was significantly higher on the cycle ergometer (p < 0.001). Conclusion: Peak VO2 is higher on treadmill than on cycle ergometer in severe HFrEF patients. In addition, VE/VCO2 slope is not a modality dependent parameter and is not related to the patients’ effort during CPET.


2021 ◽  
Author(s):  
Szymon Price ◽  
Szczepan Wiecha ◽  
Igor Cieśliński ◽  
Daniel Śliż ◽  
Przemysław Seweryn Kasiak ◽  
...  

Abstract Cardiopulmonary exercise testing (CPET) is the method of choice to assess aerobic fitness. Previous research was ambiguous as to whether treadmill (Tr) and cycle ergometry (CE) results are transferrable or different between testing modalities in triathletes. The aim of this paper was to investigate the differences in HR and VO2 at maximum exertion and at anaerobic threshold (AT) and respiratory compensation point (RCP) and evaluate their association with body fat (BF), fat free mass (FFM), and body mass index (BMI). 143 adult (n = 18 female), amateur, Caucasian triathletes had both Tr, and CE CPET performed. The male group was divided into < 40 years (n = 80) and > 40years (n = 45). Body composition was measured with bioelectrical impedance before tests. Differences were evaluated using paired T-tests and associations were evaluated in males using multiple linear regression (MLR). Significant differences were found in VO2 and HR at maximum exertion, at AT and at RCP between CE and Tr testing, in both males and females. VO2AT was 38.8(± 4.6) ml/kg/min in Tr vs 32.8(± 5.4) in CE in males and 36.0(± 3.6) vs 32.1(± 3.8) in females (p < 0.001). HRAT was 149 (± 10) bpm in Tr vs 136 (± 11) in CE in males and 156 (± 7) vs 146 (± 11) in females (p < 0.001). VO2max was 52 (± 6) ml/kg/min vs 49 (± 7) in CE in males and 45.3 (± 4.9) in Tr vs 43.9 (± 5.2) in females (p < 0.001). HRmax was 183 (± 10) bpm in Tr vs 177 (± 10) in CE in males and 183 (± 9) vs 179 (± 10) in females (p < 0.001). MLR showed that BMI, BF and FFM are significantly associated with differences in HR and VO2 at maximum, AT and RCP in males aged > 40. Both tests should be used independently to achieve optimal fitness assessment and further training planning.


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