scholarly journals Investigation of Blood Lipid Levels and Statin Interventions in Outpatients With Coronary Heart Disease in China

2008 ◽  
Vol 72 (12) ◽  
pp. 2040-2045 ◽  
Author(s):  
Dayi Hu ◽  
Jue Li ◽  
Xiankai Li ◽  
for the China Cholesterol Education
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Blood Lipid ◽  
Lipid Levels ◽  
Blood Lipid Levels

scholarly journals Non-HDL-C Is More Stable Than LDL-C in Assessing the Percent Attainment of Non-fasting Lipid for Coronary Heart Disease Patients

2021 ◽  
Vol 8 ◽  
Author(s):  
Li-Ling Guo ◽  
Yan-qiao Chen ◽  
Qiu-zhen Lin ◽  
Feng Tian ◽  
Qun-Yan Xiang ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Statin Therapy ◽  
Blood Lipids ◽  
Blood Lipid ◽  
Lipid Levels ◽  
Short Term ◽  
C Statistic ◽  
Blood Lipid Levels

This study aimed to compare the percentage attainment of fasting and non-fasting LDL-C and non-HDL-C target levels in coronary heart disease (CHD) patients receiving short-term statin therapy. This study enrolled 397 inpatients with CHD. Of these, 197 patients took statins for <1 month (m) or did not take any statin before admission (CHD1 group), while 204 patients took statins for ≥1 m before admission (CHD2 group). Blood lipid levels were measured at 0, 2, and 4 h after a daily breakfast. Non-fasting LDL-C and non-HDL-C levels significantly decreased after a daily meal (P < 0.05). Both fasting and non-fasting LDL-C or non-HDL-C levels were significantly lower in the CHD2 group. The percentage attainment of LDL-C <1.4 mmol/L at 2 and 4 h after a daily breakfast was significantly higher than that during fasting (P < 0.05), but the percent attainment of non-fasting non-HDL-C <2.2 mmol/L was close to its fasting value (P > 0.05). Analysis of c-statistic showed that non-fasting cut-off points for LDL-C and non-HDL-C were 1.19 and 2.11 mmol/L, corresponding to their fasting goal levels of 1.4 and 2.2 mmol/L, respectively. When post-prandial LDL-C and non-HDL-C goal attainments were re-evaluated using non-fasting cut-off points, there were no significant differences in percentage attainment between fasting and non-fasting states. Non-HDL-C is more stable than LDL-C in assessing the percent attainment of non-fasting lipid for coronary heart disease patients. If we want to use LDL-C to assess the percent attainment of post-prandial blood lipids, we may need to determine a lower non-fasting cut-off point.

scholarly journals Non-HDL-C is  more stable  than LDL-C in assessing the percent attainment of non-fasting lipid for coronary heart disease patients

2020 ◽  
Author(s):  
Li-ling Guo ◽  
Yan-qiao Chen ◽  
Qiu-zhen Lin ◽  
Feng Tian ◽  
Li-yuan Zhu ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Statin Therapy ◽  
Blood Lipids ◽  
Blood Lipid ◽  
Lipid Levels ◽  
Short Term ◽  
C Statistic ◽  
Blood Lipid Levels

Abstract Background: This study aimed to compare the percentage attainment of fasting and non-fasting LDL-C and non-HDL-C target levels in coronary heart disease (CHD) patients receiving short-term statin therapy.Methods: This study enrolled 397 inpatients with CHD. Of these, 197 patients took statins for < 1 month (m) or did not take any statin before admission (CHD1 group), while 204 patients took statins for ≥ 1 m before admission (CHD2 group). Blood lipid levels were measured at 0 h, 2 h, and 4 h after a daily breakfast.Results: Non-fasting LDL-C and non-HDL-C levels significantly decreased after a daily meal (P < 0.05). Both fasting and non-fasting LDL-C or non-HDL-C levels were significantly lower in the CHD2 group. The percentage attainment of LDL-C < 1.4 mmol/L at 2 h and 4 h after a daily breakfast was significantly higher than that during fasting (P < 0.05), but the percent attainment of non-fasting non-HDL-C < 2.2 mmol/L was close to its fasting value (P > 0.05). Analysis of c-statistic showed that non-fasting cut-off points for LDL-C and non-HDL-C were 1.19 mmol/L and 2.11 mmol/L, corresponding to their fasting goal levels of 1.4 mmol/L and 2.2 mmol/L, respectively. When postprandial LDL-C and non-HDL-C goal attainments were re-evaluated using non-fasting cut-off points, there were no significant differences in percentage attainment between fasting and non-fasting states.Conclusions: Non-HDL-C is more stable than LDL-C in assessing the percent attainment of non-fasting lipid for coronary heart disease patients. If we want to use LDL-C to assess the percent attainment of postprandial blood lipids, we may need to determine a lower non-fasting cut-off point.

scholarly journals The effects of almond consumption on fasting blood lipid levels: a systematic review and meta-analysis of randomised controlled trials

2016 ◽  
Vol 5 ◽  
Author(s):  
Kathy Musa-Veloso ◽  
Lina Paulionis ◽  
Theresa Poon ◽  
Han Youl Lee
Keyword(s):  
Systematic Review ◽  
Heart Disease ◽  
Randomised Controlled Trials ◽  
Large Scale ◽  
Meta Analysis ◽  
Blood Lipid ◽  
Controlled Trials ◽  
Lipid Levels ◽  
Randomised Controlled ◽  
Blood Lipid Levels

AbstractA systematic review and meta-analysis of randomised controlled trials was undertaken to determine the effects of almond consumption on blood lipid levels, namely total cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), TAG and the ratios of TC:HDL-C and LDL-C:HDL-C. Following a comprehensive search of the scientific literature, a total of eighteen relevant publications and twenty-seven almond-control datasets were identified. Across the studies, the mean differences in the effect for each blood lipid parameter (i.e. the control-adjusted values) were pooled in a meta-analysis using a random-effects model. It was determined that TC, LDL-C and TAG were significantly reduced by −0·153 mmol/l (P < 0·001), −0·124 mmol/l (P = 0·001) and −0·067 mmol/l (P = 0·042), respectively, and that HDL-C was not affected (−0·017 mmol/l; P = 0·207). These results are aligned with data from prospective observational studies and a recent large-scale intervention study in which it was demonstrated that the consumption of nuts reduces the risk of heart disease. The consumption of nuts as part of a healthy diet should be encouraged to help in the maintenance of healthy blood lipid levels and to reduce the risk of heart disease.

scholarly journals Optimal cut-off points after a daily meal corresponding to fasting goal levels of LDL-C and non-HDL-C in Chinese patients with coronary heart disease

2020 ◽  
Author(s):  
Li-Ling Guo ◽  
Yan-qiao Chen ◽  
Qiu-zhen Lin ◽  
Feng Tian ◽  
Qun-Yan Xiang ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Blood Lipids ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Blood Lipid ◽  
Lipoprotein Cholesterol ◽  
Chinese Patients ◽  
C Statistic ◽  
Blood Lipid Levels

Abstract Background: Although the detection of non-fasting blood lipids has been recommended in patients with coronary heart disease (CHD), the non-fasting cut-off points corresponding to the fasting goals of LDL-C < 1.8 mmol/Land non-HDL-C < 2.6 mmol/L, respectively, have not been explored. Methods: This study enrolled 397 inpatients with CHD. One hundred and ninety-seven patients took statins for < 1 month (m) or did not take any statin before admission (i.e. CHD1 group), while 204 patients took statins for ≥ 1 m before admission (i.e. CHD2 group). Blood lipid levels were measured at 0 h, 2 h, and 4 h after a daily breakfast. Results: Non-fasting low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) levels significantly decreased after a daily meal ( P < 0.05). Both fasting and non-fasting LDL-C or non-HDL-C levels were significantly lower in the CHD2 group. The percent attainment of LDL-C < 1.8 mmol/L at 2 h or 4 h after a daily breakfast was significantly higher than that of its fasting point ( P < 0.05), whereas that of non-HDL-C < 2.6 mmol/L was significantly higher only at 4 h ( P < 0.05). Analysis of c-statistic showed that non-fasting cut-off points for LDL-C and non-HDL-C were 1.5 mmol/L and 2.4 mmol/L, corresponding to their fasting goal levels of 1.8 mmol/L and 2.6 mmol/L, respectively. When postprandial LDL-C and non-HDL-C goal attainments were re-evaluated by non-fasting cut-off points, there were no significant differences in percent attainment between fasting and non-fasting states. Conclusions: Determination ofnon-fasting cut-off points is important to evaluate the efficacy of cholesterol-lowering therapy if blood lipids are detected after a daily meal.

scholarly journals Blood lipid of preadolescent boys of well-to-do families

2017 ◽  
Vol 41 (1) ◽  
pp. 19
Author(s):  
Muzief Munir ◽  
Sudiro Darmoprawiro
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cholesterol Level ◽  
Causes Of Death ◽  
Adult Life ◽  
Blood Lipid ◽  
Blood Cholesterol ◽  
Elevated Blood ◽  
Blood Cholesterol Level ◽  
Blood Lipid Levels

Coronary heart disease is presently one of the leading causes of death In adults in many countries, including in Indonesia. It is well known that elevated levels of cholesterol in children are closely associated with hypercholesterolemia and coronary heart disease in adult life. This study was conducted in an attempt to find a preliminary insight of the magnitude of the problem of hypercholesterolemia In children In Indonesia as a developing country. The blood lipid levels of 54 preadolescent boys from well-Io-do families were analyzed. Two-third of those children were shown to have elevated blood cholesterol level, and even one third or 16 out of 54 preadolescents boys investigated suffered from hypercholesterolemia. We conclude that elevated blood cholesterol level is frequently found among large-framed and obese Indonesian children.

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