The effect of haemolysis on certain canine serum chemistry parameters

1990 ◽  
Vol 24 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Barbara L. Leard ◽  
Richard D. Alsaker ◽  
William P. Porter ◽  
LaDean P. Sobel
Keyword(s):  
Historical Data ◽  
Clinical Chemistry ◽  
Haemoglobin Concentration ◽  
Statistical Analyses ◽  
Serum Chemistry ◽  
Canine Serum ◽  
The Relationship

Haemolysis has been known to cause artefacts in certain canine serum chemistry parameters. These parameters are often used by researchers to detect toxicity in certain studies; haemolysis, therefore, can make serum chemistry interpretation very difficult. In order to determine whether a relationship existed between the level of haemolysis and certain canine serum chemistry parameters, haemolysis was artificially induced by adding a haemolysate of known haemoglobin concentration to serum specimens. A routine clinical chemistry profile was performed on each specimen. Statistical analyses were performed on the results to examine the relationship between level of haemolysis and serum chemistry results. Interpretation of serum chemistry results of haemolysed canine sera paralleled, in most cases, human historical data.

scholarly journals Exploratory Factor Analysis of Rainbow Trout Serum Chemistry Variables

2021 ◽  
Vol 18 (4) ◽  
pp. 1537
Author(s):  
Maurizio Manera
Keyword(s):  
Factor Analysis ◽  
Rainbow Trout ◽  
Exploratory Factor Analysis ◽  
Clinical Chemistry ◽  
Blood Chemistry ◽  
Hepatosomatic Index ◽  
Physiological Status ◽  
Serum Chemistry ◽  
Clinical Tool ◽  
Correlated Variables

Clinical chemistry offers a valuable, affordable, moderately invasive, and nondisruptive way to assess animal physiological status and wellness within defined ranges and is widely used as a diagnostic clinical tool. Because of physiological differences between mammals, clinical correlates of blood chemistry variables are not known in detail in fish, in which tissue/organ function tests are inferred from mammal-derived clinical chemistry data. The aim of the present study was to apply exploratory factor analysis on a serum chemistry dataset from clinically healthy, reared rainbow trout Oncorhynchusmykiss (Walbaum, 1792) to select the most correlated variables and to test for possible underlying factors explaining the observed correlations as possible physiological status estimates in trout. The obtained factors were tested for correlation with hepatosomatic and splenosomatic indexes. Thirteen highly correlated variables were selected out of 18 original serum chemistry variables, and three underlying factors (Factors 1, 2, and 3) were identified that explained the observed correlations among variables. Moreover, Factor 1 correlated negatively with the hepatosomatic index and Factors 2 and 3 negatively with the splenosomatic index. The obtained factors were tentatively associated with: protein (liver) metabolism (Factor 1), cell turnover (Factor 2), and lipid (muscle) metabolism (Factor 3).

scholarly journals Astronomical phenomena in Dresden codex

2013 ◽  
pp. 53-64
Author(s):  
V. Böhm ◽  
B. Böhm ◽  
J. Klokocník ◽  
J. Vondrák ◽  
J. Kostelecký
Keyword(s):  
Historical Data ◽  
Large Uncertainty ◽  
Astronomical Data ◽  
Julian Date ◽  
History Of ◽  
Solar Eclipses ◽  
Dresden Codex ◽  
The Relationship

The relationship between Maya and our calendar is expressed by a coefficient known as ?correlation? which is a number of days that we have to add to the Mayan Long Count date to get Julian Date used in astronomy. There is surprisingly large uncertainty in the value of the correlation, yielding a shift between both calendars (and thus between the history of Maya and of our world) to typically several hundred years. There are more than 50 diverse values of the correlation, some of them derived from historical, other by astronomical data. We test here (among others) the well established Goodman-Mart?nez-Thompson correlation (GMT), based on historical data, and the B?hms? one (B&B), based on astronomical data decoded from the Dresden Codex (DC); this correlation differs by about +104 years from the GMT. In our previous works we used several astronomical phenomena as recorded in the DC for a check. We clearly demonstrated that (i) the GMT was not capable to predict these phenomena that really happened in nature and (ii) that the GMT predicts them on the days when they did not occur. The phenomena used till now in the test are, however, short-periodic and the test then may suffer from ambiguity. Therefore, we add long-periodic astronomical phenomena, decoded successfully from the DC, to the testing. These are (i) a synchrony of Venusian heliacal risings with the solar eclipses, (ii) a synchrony of Venus and Mars conjunctions with the eclipses, (iii) conjunctions of Jupiter and Saturn repeated in a rare way, and (iv) a synchrony of synodic and sideric periods of Mercury with the tropical year. Based on our analysis, we find that the B&B correlation yields the best agreement with the astronomical phenomena observed by the Maya. Therefore we recommend to reject the GMT and support the B&B correlation.

Validation of the Customer-Based Corporate Reputation Scale in a Retail Context

2014 ◽  
Vol 56 (5) ◽  
pp. 655-671 ◽  
Author(s):  
Nic S. Terblanche
Keyword(s):  
Developing Country ◽  
Corporate Reputation ◽  
Customer Orientation ◽  
Corporate Citizenship ◽  
Statistical Analyses ◽  
Great Care ◽  
Five Dimensions ◽  
Environmentally Responsible ◽  
The One ◽  
The Relationship

A positive corporate reputation held by customers is important for both financial and customer outcome variables. However, limited research has been undertaken to examine the relationship between corporate reputation and customer-related behaviours. This paper deals with a study in which the shortened customer-based corporate reputation (CBCR) scale of Walsh et al. (2009) was validated in a study of supermarket customers in a developing country. The findings support only two of the five dimensions of the Walsh et al. scale. These are customer orientation and competitiveness of the firm. None of the original reputation dimensions or items associated with good corporate citizenship, such as good employer and being socially and environmentally responsible, was part of the dimensions that remained after the statistical analyses. Both customer orientation and competitiveness of the firm are strongly associated with important outcome variables such as trust, loyalty, repatronage intention and overall reputation. The findings of this study reiterate the view that great care should be exercised when scales are considered for application in a context not similar to the one where the scale was developed.

Haematological and serological response of broiler chickens to varying levels of direct fed microbes as feed additive

2020 ◽  
Vol 47 (3) ◽  
pp. 90-98
Author(s):  
D. N. Onunkwo ◽  
O. A. Ekine
Keyword(s):  
Blood Cell ◽  
Broiler Chickens ◽  
Haemoglobin Concentration ◽  
Feed Additive ◽  
Total Serum Protein ◽  
Total Serum ◽  
Broiler Chicks ◽  
Serological Response ◽  
Serum Chemistry ◽  
Intestinal Immunity

Several efforts are being made to find the possibilities of utilizing Direct fed microbes (DFM) that has a potential to replace antibiotics as a result of its ability to prevent internal colonization of enteropathogenic enzymes, stimulate intestinal immunity of broiler chickens and reduce stress in animals. A studywas conducted using 120, one day-old Ross 308 broiler chicks to evaluate blood and serum chemistry response to direct fed microbes. The broiler chicks were obtained from a reputable hatchery and randomly assigned to four dietary treatments, each with three replicates of ten birds per treatment. The treatments were T1, T2, T3 and T4, with levels of inclusion of direct fed microbes (DFM) at 0, 2.5, 5% and 7.5%, respectively. The birds were assigned to these treatment diets, feed and water was given ad libitum throughout the duration of the experiment which lasted for 56 days. The experimental design was Completely Randomized Design (CRD). At the end of the experiment blood samples were collected from the chickens and taken to the laboratory for haematological and serum chemistry analysis. The haematological characteristics of the broiler chickens showed that there was no significant (P>0.05) in haemoglobin (Hb), Packed Cell Volume (PCV), Red Blood Cell (RBC), White Blood Cell (WBC), Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH) and Mean Cell Haemoglobin Concentration (MCHC). The WBC portrayed decreasing trend as the level of DFM increased, also the Hb, MCV and MCH portrayed an increasing trend as the DFM increased in the treatment diet up to the 5% inclusion level. The serum chemistry result shows that there were significant differences (P<0.05) in total serum protein and globulin whereas no significant differences (P>0.05) were observed in serum albumin, glucose, urea and creatinine. It could be concluded that fed diet 2 containing 2.5% DFM performed better as they compete favourably with the control. Broiler chickenss fed diet 2 also had a balanced physiological system

A Study of the Cascading Effects of Ambulance Diversion among Hospitals

2013 ◽  
pp. 32-41
Author(s):  
Abey Kuruvilla ◽  
Suraj M. Alexander ◽  
Xiaolin Li
Keyword(s):  
Conditional Probability ◽  
Historical Data ◽  
Research Effort ◽  
Statistical Analyses ◽  
Medical Systems ◽  
Cascading Effects ◽  
Ambulance Diversion ◽  
The Status ◽  
Emergency Medical Systems ◽  
The Impact

This research effort is undertaken to determine the impact that one hospital’s diversion status has on other hospitals in a region and the strength of these interactions. The conditional probability of one hospital going on diversion given that another is already on diversion is evaluated. Based on this analysis, the strength of interactions among the hospitals is established. Through statistical analyses of historical data, the strength of the mutual effects of diversion among a collection of hospitals is determined. These effects are mutual if one hospital’s diversion status affected another’s, then the reverse was also true. The intensity of these interactions between hospitals is varied, some being stronger than others. The model illustrates an approach to studying the cascading effects of diversion among hospitals in a region. This is important, because the status of any hospital in a region can signal the likelihood of impending diversion in every other hospital in the region. This allows actions that might prevent the occurrence of diversion or mitigate the cascading effects of Emergency Medical Systems diversion.

A Study of the Cascading Effects of Ambulance Diversion among Hospitals

2011 ◽  
Vol 3 (3) ◽  
pp. 60-70 ◽  
Author(s):  
Abey Kuruvilla ◽  
Suraj M. Alexander ◽  
Xiaolin Li
Keyword(s):  
Conditional Probability ◽  
Historical Data ◽  
Research Effort ◽  
Statistical Analyses ◽  
Medical Systems ◽  
Cascading Effects ◽  
Ambulance Diversion ◽  
The Status ◽  
Emergency Medical Systems ◽  
The Impact

This research effort is undertaken to determine the impact that one hospital’s diversion status has on other hospitals in a region and the strength of these interactions. The conditional probability of one hospital going on diversion given that another is already on diversion is evaluated. Based on this analysis, the strength of interactions among the hospitals is established. Through statistical analyses of historical data, the strength of the mutual effects of diversion among a collection of hospitals is determined. These effects are mutual if one hospital’s diversion status affected another’s, then the reverse was also true. The intensity of these interactions between hospitals is varied, some being stronger than others. The model illustrates an approach to studying the cascading effects of diversion among hospitals in a region. This is important, because the status of any hospital in a region can signal the likelihood of impending diversion in every other hospital in the region. This allows actions that might prevent the occurrence of diversion or mitigate the cascading effects of Emergency Medical Systems diversion.

Identification of two species of alpha motoneurons in cat's plantaris pool

1977 ◽  
Vol 40 (1) ◽  
pp. 16-25 ◽  
Author(s):  
D. A. Harris ◽  
E. Henneman
Keyword(s):  
Visual Inspection ◽  
Repetitive Stimulation ◽  
Ventral Root ◽  
Statistical Analyses ◽  
The Other ◽  
Small Samples ◽  
The Relationship ◽  
Decerebrate Cats ◽  
Two Populations ◽  
Stimulation Of

1. Single units of the plantaris pool were isolated in ventral root filaments of decerebrate cats and their critical firing levels (CFLs) were determined. Motoneurons of similar size, as judged by their CFLs and other criteria, were compared in firing rate (FR) during repetitive stimulation of the plantaris nerve. 2. Such units either differed very little or quite widely, suggesting that they were sampled randomly from two populations, one firing rapidly, the other slowly. The relationship between the two rates remained approximately constant, regardless of the intensity or rate of input the units received, as long as both of them discharged rhythmically. 3. In single experiments 10-15 of the smallest units in the pool (all with CFLs in the 0-8% range) were isolated and compared. Statistical analyses and visual inspection of these small samples again suggested the existence of two species of motoneurons. 4. Statistical analyses also indicated that the FRs of units in single experiments were not sampled from any one of a variety of parametric, single-modal distributions. This suggests that the data were sampled from a distribution having more than one mode, indicating the existence of separate populations or species of motoneurons among the small units of the pool (0-8% range of CFL). 5. Pooling of the normalized data from different experiments revealed a bimodal histogram, reinforcing the conclusion that there are two species of small alpha motoneurons in the plantaris pool.

scholarly journals Haematological Profile and Intensity of Urogenital Schistosomiasis in Ghanaian Children

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Justice Afrifa ◽  
Desmond Gyedu ◽  
Eric Ofori Gyamerah ◽  
Samuel Essien-Baidoo ◽  
Isaac Mensah-Essilfie
Keyword(s):  
Haemoglobin Concentration ◽  
Urogenital Schistosomiasis ◽  
Mixed Cell ◽  
Mean Cell Volume ◽  
Distribution Width ◽  
Cell Percentage ◽  
Haematological Profile ◽  
Blood And Urine Samples ◽  
Study Participants ◽  
The Relationship

Background. Urogenital schistosomiasis is a widely contracted parasitic helminth infection often associated with haematological abnormalities.Aim. We investigated the relationship between the haematological profile and the intensity of schistosomiasis among children in the Yeji district.Materials and Methods. A total of 100 participants comprising 50Schistosoma haematobium(S. haematobium) infected and 50 noninfected controls aged 6–17 years matched for age and sex were recruited into the study. Blood and urine samples were collected and haematological profile and presence ofS. haematobiumeggs were assessed using standard protocols.Results. Haemoglobin (HGB) (P<0.0001), haematocrit (HCT) (P<0.0001), mean cell volume (MCV) (P=0.0053), mean cell haemoglobin (MCH) (P<0.0001), and mean cell haemoglobin concentration (MCHC) (P=0.005) levels were reduced in cases compared to controls. Mixed cell percentage (MXD) (P=0.018) and red blood cell distribution width (RDW-CV) (P=0.012) were significantly elevated among cases as compared to controls. Haematuria was a clinical characteristic of heavy infection.Conclusion.S. haematobiuminfection creates an imbalance in the haematological profile. We found low HGB, HCT, MCV, MCH, and MCHC levels coupled with increased % MXD count and RDW-CV. Also, low MCV, MCH, and MCHC and high % MXD count are independently associated withS. haematobiuminfection among our study participants.

scholarly journals IFCC Reference System for Measurement of Hemoglobin A1c in Human Blood and the National Standardization Schemes in the United States, Japan, and Sweden: A Method-Comparison Study

2004 ◽  
Vol 50 (1) ◽  
pp. 166-174 ◽  
Author(s):  
Wieland Hoelzel ◽  
Cas Weykamp ◽  
Jan-Olof Jeppsson ◽  
Kor Miedema ◽  
John R Barr ◽  
...  
Keyword(s):  
Reference System ◽  
Clinical Chemistry ◽  
Method Comparison ◽  
Reference Method ◽  
The United States ◽  
Reference Laboratory ◽  
Regression Equations ◽  
National Programs ◽  
Method Comparison Study ◽  
The Relationship

Abstract Background: The national programs for the harmonization of hemoglobin (Hb)A1c measurements in the US [National Glycohemoglobin Standardization Program (NGSP)], Japan [Japanese Diabetes Society (JDS)/Japanese Society of Clinical Chemistry (JSCC)], and Sweden are based on different designated comparison methods (DCMs). The future basis for international standardization will be the reference system developed by the IFCC Working Group on HbA1c Standardization. The aim of the present study was to determine the relationships between the IFCC Reference Method (RM) and the DCMs. Methods: Four method-comparison studies were performed in 2001–2003. In each study five to eight pooled blood samples were measured by 11 reference laboratories of the IFCC Network of Reference Laboratories, 9 Secondary Reference Laboratories of the NGSP, 3 reference laboratories of the JDS/JSCC program, and a Swedish reference laboratory. Regression equations were determined for the relationship between the IFCC RM and each of the DCMs. Results: Significant differences were observed between the HbA1c results of the IFCC RM and those of the DCMs. Significant differences were also demonstrated between the three DCMs. However, in all cases the relationship of the DCMs with the RM were linear. There were no statistically significant differences between the regression equations calculated for each of the four studies; therefore, the results could be combined. The relationship is described by the following regression equations: NGSP-HbA1c = 0.915(IFCC-HbA1c) + 2.15% (r2 = 0.998); JDS/JSCC-HbA1c = 0.927(IFCC-HbA1c) + 1.73% (r2 = 0.997); Swedish-HbA1c = 0.989(IFCC-HbA1c) + 0.88% (r2 = 0.996). Conclusion: There is a firm and reproducible link between the IFCC RM and DCM HbA1c values.

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