Post-exposure prophylaxis following sexual intercourse

2004 ◽  
Vol 15 (12) ◽  
pp. 844-846 ◽  
Author(s):  
C Newey ◽  
N Nwokolo
Keyword(s):  
Sexual Intercourse ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Exposure Prophylaxis

scholarly journals HIV Non-Occupational Post-Exposure Prophylaxis Awareness Among Undergraduate Students of a Private University in South-West Nigeria

2020 ◽  
Vol 3 (2) ◽  
pp. 19-27
Author(s):  
Charles J Elikwu ◽  
Tinuade A Ajani ◽  
Victor U Nwadike ◽  
Babtunde Tayo ◽  
Chika C Okangba ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Occupational Exposure ◽  
Sexual Intercourse ◽  
Undergraduate Students ◽  
Private University ◽  
Sub Saharan Africa ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Immunodeficiency Virus ◽  
Exposure Prophylaxis

Objectives: The Human Immunodeficiency virus causes an infection of public health importance with about 71% of the global burden in Sub-Saharan Africa. In Nigeria, 3.2 million people are living with HIV, and 838,000 - 1.3 million of the cases are found among youths. Although Non- Occupational Human Immunodeficiency Virus (HIV) post-exposure prophylaxis (nPEP) is a safe and efficacious method of HIV prevention, it remains an underutilized prevention strategy in Nigeria.  This study aimed to determine the awareness level of nPEP after sexual and other non-occupational exposure to HIV among undergraduate students of a private University. Methods: A descriptive cross-sectional survey was conducted among 395 undergraduates’ students. Data was collected by pre-tested structured self-administered questionnaires. Data obtained from the study were analyzed using the IBM SPSS Statistics version 20 software program and Frequency distribution tables with percentages and cross-tables were used for data description. Results: About 42.8% were aware of nPEP. Most of the respondents 361 (91.4%) knew that PEP is to be given after HIV exposure risk following sexual intercourse. Although 79.5% of the respondents indicated that they will see their physician after unprotected sexual intercourse and other non-occupational exposure to HIV, the majority neither knows about nPEP initiation time, 247 (62.5%) nor its duration, 286 (72.4%). Conclusions: A low level of awareness was observed among our study participants, therefore, consistent health education and promotion of nPEP will improve its awareness, uptake, and possibly reduce the prevalence of HIV among our youths.

scholarly journals Nonoccupational post-exposure prophylaxis for HIV after sexual intercourse among women in Brazil: Risk profiles and predictors of loss to follow-up

Medicine ◽  
2019 ◽  
Vol 98 (39) ◽  
pp. e17071
Author(s):  
Alexandre Grangeiro ◽  
Maria Mônica Paulino do Nascimento ◽  
Eliana Miura Zucchi ◽  
Dulce Ferraz ◽  
Maria Mercedes Escuder ◽  
...  
Keyword(s):  
Sexual Intercourse ◽  
Post Exposure Prophylaxis ◽  
Risk Profiles ◽  
Loss To Follow Up ◽  
Post Exposure ◽  
Exposure Prophylaxis

A fatal rabies case and experiences of a mass post exposure prophylaxis among healthcare workers

2021 ◽  
Author(s):  
Alper Sener ◽  
Canan Akman ◽  
Anil Akca ◽  
Behcet Varisli
Keyword(s):  
Emergency Medicine ◽  
Infection Control ◽  
Sexual Intercourse ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Group I ◽  
Significant Difference ◽  
Group Ii ◽  
Radiology Technicians ◽  
Exposure Prophylaxis

AbstractWe aimed to monitor the adverse effects (AE) and efficacy of post exposure prophylaxis (PEP) in health care workers (HCWs) exposed to a rabies patient. In this study 109 HCWs and eight household contacts were PEP candidates. Contact persons without infection control precautions were in Group I (high risk-82 cases). HCWs indirectly exposed to environmental surfaces were classified in Group II (low risk-35 cases). PEP schedule was rabies vaccine (RBV) + equine rabies immunoglobulin (eRIG) in Group I and only RBV in Group II. Local and systemic AE were observed in all cases. Efficacy of post exposure prophylaxis (PEP) was determined by rabies development in a six month follow-up. 585 doses of RBV have been used in 117 cases and eRIG has been used in 82 cases. 32 Nurses (39%); 22 emergency medicine technicians (26.8%); 12 doctors (14%); six laboratory technicians (0.07%); six radiology technicians (0.07%); four cleaners (0.05%) were in Group I (82 cases), respectively. One doctor, laboratory technician, nurse and radiology technician (0.02%); two emergency medicine technicians (0.04%) and nine cleaners (25.7%) were in Group II (35 cases), respectively. Routes of transmission were blood in five (0.06%); saliva in 14 (17%); sweat in 50 (61%); CSF/serum in five (0.06%); sexual intercourse in one (0.01%); personal equipment in seven (0.09%) in Group I, respectively. Indirect contact was the only route in Group II. The most common local and systemic AE were seen in Group I; pain at injection side (19 cases) and fever (13 cases). Both of them showed statistically significant difference (P<0.05). Allergic rash has been seen at only one case. PEP failed in one case where the possible exposure way was sexual intercourse. PEP is the safest way to prevent rabies. Infection control precautions were still not enough applied. eRIGs are also safe and have rare AE.

Low awareness and use of post-exposure prophylaxis among adolescents and young adults in South Africa: implications for the prevention of new HIV infections

2020 ◽  
Vol 19 (3) ◽  
pp. 242-248
Author(s):  
Anthony Idowu Ajayi ◽  
Mohammed Sanusi Yusuf ◽  
Elmon Mudefi ◽  
Oladele Vincent Adeniyi ◽  
Ntombana Rala ◽  
...  
Keyword(s):  
South Africa ◽  
Young Adults ◽  
Hiv Infections ◽  
Adolescents And Young Adults ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Exposure Prophylaxis

Study of sharp injuries and blood splash exposures among healthcare workers in a tertiary hospital in Bangalore

2016 ◽  
Vol 12 (3) ◽  
Author(s):  
Shalini Sivananjiah Pradeep ◽  
Suman Gadicherla Raghu ◽  
Prathab A G ◽  
Banashankari G Rudresh ◽  
Radhika Kunnavil
Keyword(s):  
Healthcare Workers ◽  
Tertiary Hospital ◽  
Post Exposure Prophylaxis ◽  
Care Hospital ◽  
Post Exposure ◽  
Increased Risk ◽  
Management Procedures ◽  
Exposure Prophylaxis ◽  
Sharps Injury ◽  
Sharps Injuries

The working environment of healthcare workers (HCW) exposes them to sharp injuries. This communication attempts to examine the injury registers, incidence of sharps injuries and blood splash exposures, and the post-exposure prophylaxis status of employees in a tertiary care hospital. Analysis included records form 54 locations of two units of a tertiary hospital attached to a Medical College. Maintenance of the injury register overall was highly satisfactory in both units. Two hundred and nine injuries were recorded from both units of the hospital. The majority of injuries (60.5%) occurred in the age group of 20-30 years with 70% among females. Waste handlers were at increased risk during waste management procedures. Thirty two percent of sharps injury injuries occurred in wards. Of the ward nursing staff, 25.3% received sharps injuries. Post-exposure prophylaxis for Hepatitis B (primary dose) was given to 25 HCWs; 11 received booster doses. The basic regimen for HIV post-exposure prophylaxis was given to 4 HCWs. Awareness about records maintenance, regular documentation, awareness and training, and implementation of appropriate preventive measures can reduce the incidence of injuries. Key words: Sharps, injury register, Health care workers (HCW),Post exposure prophylaxis (PEP)

scholarly journals 986. Improvement in Administration of HIV Post-Exposure Prophylaxis in the Emergency Department Following Sexual Assault

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S521-S522
Author(s):  
Jennifer R Silva-Nash ◽  
Stacie Bordelon ◽  
Ryan K Dare ◽  
Sherrie Searcy
Keyword(s):  
Emergency Department ◽  
Sexual Assault ◽  
Hiv Transmission ◽  
Post Exposure Prophylaxis ◽  
Intervention Period ◽  
Post Intervention ◽  
Post Exposure ◽  
Assault Victims ◽  
Exposure Prophylaxis

Abstract Background Nonoccupational post exposure prophylaxis (nPEP) following sexual assault can prevent HIV transmission. A standardized Emergency Department (ED) protocol for evaluation, treatment, and follow up for post assault victims was implemented to improve compliance with CDC nPEP guidelines. Methods A single-center observational study of post sexual assault patients before/after implementation of an ED nPEP protocol was conducted by comparing the appropriateness of prescriptions, labs, and necessary follow up. A standardized order-set based on CDC nPEP guidelines, with involvement of an HIV pharmacist and ID clinic, was implemented during the 2018-2019 academic year. Clinical data from pre-intervention period (07/2016-06/2017) was compared to post-intervention period (07/2018-08/2019) following a 1-year washout period. Results During the study, 147 post-sexual assault patients (59 Pre, 88 Post) were included. One hundred thirty-three (90.4%) were female, 68 (46.6%) were African American and 133 (90.4%) were candidates for nPEP. Median time to presentation following assault was 12.6 hours. nPEP was offered to 40 (67.8%) and 84 (95.5%) patients (P&lt; 0.001) and ultimately prescribed to 29 (49.2%) and 71 (80.7%) patients (P&lt; 0.001) in pre and post periods respectively. Renal function (37.3% vs 88.6%; P&lt; 0.001), pregnancy (39.0% vs 79.6%; P&lt; 0.001), syphilis (3.4% vs 89.8%; P&lt; 0.001), hepatitis B (15.3% vs 95.5%; P&lt; 0.001) and hepatitis C (27.1% vs 94.3%) screening occurred more frequently during the post period. Labratory, nPEP Prescription and Follow up Details for Patients Prescribed nPEP Conclusion The standardization of an nPEP ED protocol for sexual assault victims resulted in increased nPEP administration, appropriateness of prescription, screening for other sexually transmitted infectious and scheduling follow up care. While guideline compliance dramatically improved, further interventions are likely warranted in this vulnerable population. Disclosures Ryan K. Dare, MD, MS, Accelerate Diagnostics, Inc (Research Grant or Support)

scholarly journals Rabies Post-Exposure Prophylaxis in Germany-what are the challenges?

2021 ◽  
pp. 1-10
Author(s):  
P Meyerhoff ◽  
S Manekeller ◽  
N Saleh ◽  
C Boesecke ◽  
S Schlabe ◽  
...  
Keyword(s):  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Exposure Prophylaxis
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