scholarly journals An audit and service evaluation of the use of cone beam computed tomography (CBCT) in a paediatric dentistry department

2019 ◽  
Vol 48 (5) ◽  
pp. 20180393 ◽  
Author(s):  
Laith Mizban ◽  
Mohamed El-Belihy ◽  
Mina Vaidyanathan ◽  
Jackie Brown
Keyword(s):  
Paediatric Patient ◽  
Treatment Planning ◽  
Staff Training ◽  
Service Evaluation ◽  
Paediatric Dentistry ◽  
Definitive Treatment ◽  
European Guidelines ◽  
New Information ◽  
Treatment Plans ◽  
The Impact

Objectives: CBCT exposes the paediatric patient to a higher X-ray dose and risk than normal dental radiographs. This study has two components: an audit and service evaluation. The audit aims to assess whether the use of CBCT in a Paediatric Dentistry department at a London hospital complies with European guidelines (SEDENTEXCT). The service evaluation aims to explore the influence of CBCT on treatment planning. Methods: Two 6 month audit cycles were completed, where CBCT requests were audited to check whether image justifications comply with SEDENTEXCT. For the service evaluation, a total of 50 patient records were examined for the effect of CBCT on definitive treatment plans. Results: The first audit demonstrated 94% compliance with SEDENTEXCT. After instituting staff training in CBCT, compliance improved to 100%. In the service evaluation, 100% of CBCTs were found to provide information that impacted on the clinicians’ treatment planning, diagnosis and/or management. Of most significance, 44% of treatment plans were changed because of new information provided by CBCT. Conclusions: There are few studies investigating the use of CBCT in paediatric dentistry and the impact of this investigation. This service evaluation shows that CBCT can play an important role in optimising paediatric patient outcomes. The need for robust staff training in CBCT referrals to prevent over prescription is demonstrated in the audit cycles.

scholarly journals Dosimetric study of the interplay effect using three-dimensional motion phantom in proton pencil beam scanning treatment of moving thoracic tumours

2021 ◽  
pp. 1-10
Author(s):  
Hardev S. Grewal ◽  
Salahuddin Ahmad ◽  
Hosang Jin
Keyword(s):  
Treatment Planning ◽  
Three Dimensional ◽  
Spot Size ◽  
Passing Rate ◽  
Treatment Plans ◽  
Motion Phantom ◽  
Interplay Effect ◽  
The Impact ◽  
Motion Amplitude ◽  
Dose Difference

Abstract Aim: The dosimetric and clinical advantages offered by implementation of pencil beam scanning (PBS) proton therapy for moving thoracic tumours is hindered by interplay effect. The purpose of this study is to evaluate the impact of large proton beam spot size along with adaptive aperture (AA) and various motion mitigation techniques on the interplay effect for a range of motion amplitudes in a three-dimensional (3D) respiratory motion phantom. Materials and Methods: Point doses using ionisation chamber (IC) and planner dose distributions with radiochromic film were compared against the corresponding treatment planning system (TPS) information. A 3D respiratory motion phantom was scanned either for static or 4D computed tomographic (CT) technique for 6-, 10- and 14-mm motion amplitudes in SI direction. For free breathing (FB) treatment, a tumour was contoured on maximum intensity projection scan and an average scan was used for treatment planning. Each FB treatment was delivered with one, three and five volumetric repaintings (VRs). Three phases (CT40–60%) were extracted from the 4D-CT scans of each motion amplitude for the respiratory-gated treatment and were used for the treatment planning and delivery. All treatment plans were made using AA and robustly optimised with 5-mm set-up and 3·5% density uncertainty. A total of 26 treatment plans were delivered to IC and film using static, dynamic and respiratory-gated treatments combinations. A percent dose difference between IC and TPS for the point dose and gamma indices for film–TPS planner dose comparison was used. Results: The dose profile of film and TPS for the static phantom matched well, and percent dose difference between IC and TPS was 0·4%. The percent dose difference for all the gated treatments were below 3·0% except 14-mm motion amplitude-gated treatment. The gamma passing rate was more than 95% for film–TPS comparison for all gated treatment for the investigated gamma acceptance criteria. For FB treatments, the percent dose difference for 6-, 10- and 14-mm motion amplitude was 1·4%, −2·7% and −4·1%, respectively. As the number of VR increased, the percent difference between measured and calculated values decreased. The gamma passing rate met the required tolerance for different acceptance criteria except for the 14-mm motion amplitude FB treatment. Conclusion: The PBS technique for the FB thoracic treatments up to 10-mm motion amplitude can be implemented with an acceptable accuracy using large proton beam spot size, AA and robust optimisation. The impact of the interplay effect can be reduced with VR and respiratory-gated treatment and extend the treatable tumour motion amplitude.

496 The Use of Virtual Trauma Clinics (VTC) In the Assessment of Acute Hand Trauma; A Service Evaluation

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
H Creasy ◽  
S Westley ◽  
R Shah ◽  
R Mistry
Keyword(s):  
Service Evaluation ◽  
Definitive Treatment ◽  
Hand Trauma ◽  
Referral Centre ◽  
Tertiary Referral Centre ◽  
Prospective Data ◽  
Time To Surgery ◽  
Trauma Service ◽  
The Impact ◽  
Definitive Management

Abstract As a UK tertiary referral centre for hand trauma the current COVID outbreak has led to the reconfiguration of trauma services. We evaluate the impact of our newly introduced VTC on our hand trauma service, comparing a cohort of patients who were managed pre-COVID, with our current revised pathway. We carried out a service evaluation of all those patients processed by the VTC over 14 days in April 2020 (n = 184). We collected prospective data on timing of referral to assessment and surgery. This data was compared to a matched period in April 2019 (n = 162). Post VTC there has been a significant reduction in time to clerking and time to surgery (p = < 0.001), with 98.1% being clerked within 1 day of referral. Post VTC 12.9% of patients were discharged directly from VTC, all other patients had definitive treatment in a single trip. VTC has shown a clear benefit to patients with definitive management provided in a single trip in all cases. Whilst we have been able to clerk patients earlier any improvement in time to surgery depends on theatre staffing and availability, which differed in the two cohorts and certainly will as we move forward into normal services.

The impact of new information technology in the developing countries

1984 ◽  
Vol 8 (5) ◽  
pp. 213-220 ◽  
Author(s):  
Peter Thorpe
Keyword(s):  
Information Technology ◽  
Developing Countries ◽  
Staff Training ◽  
New Technology ◽  
Database System ◽  
The Political ◽  
Political Will ◽  
New Information ◽  
The Impact ◽  
Graphic Database

The major constraints to the use of new information tech nology in the developing countries are identified and discus ssed, and related to the setting up of a computerised biblio graphic database system. Examples of existing systems are given to provide guidelines as to how new technology can successfully be used in the developing countries despite these constraints. It is concluded that staff training, international cooperation and socio-political aspects (attitudes) are the prior ity areas for attention by the developing countries. New tech nology can be successfully introduced only if there is the political will and all involved are fully committed to the idea.

scholarly journals The Use of Cone Beam Computed Tomographic Imaging in a Paediatric Dentistry Department

Oral ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 45-55
Author(s):  
Claudy Henein ◽  
Shannu K Bhatia ◽  
Nicholas Drage
Keyword(s):  
Root Resorption ◽  
Imaging Modality ◽  
Treatment Plan ◽  
Service Evaluation ◽  
Paediatric Dentistry ◽  
Cone Beam ◽  
Definitive Treatment ◽  
Or Management ◽  
Paediatric Patients ◽  
Clinical Records

Cone beam computed tomography (CBCT) is an emerging radiographic imaging modality. The diagnostic benefit must exceed the individual detriment that its generally higher radiation exposure may cause. Since limited studies exist on the use and impact of CBCT in paediatric dentistry, a service evaluation was carried out to explore the reasons for CBCT referral and to identify its impact on the treatment plan and/or management in a paediatric dentistry department. Clinical records for all paediatric patients who underwent a CBCT were reviewed, to identify the reason for referral and its influence on diagnosis or management, by comparing the provisional treatment plan with the definitive treatment plan, post-CBCT. A total of 130 paediatric patients underwent CBCT in a 12-month period, of which 52 satisfied the inclusion criteria. CBCTs were most commonly requested for the localisation of unerupted/impacted teeth 14/52 (27%), assessment of supernumerary teeth 12/52 (23%), and to investigate root resorption 9/52 (17%). All CBCTs provided additional information that assisted treatment planning, diagnosis, or management and, most significantly, 16/52 (31%) of treatment plans were changed based on CBCT findings. All CBCTs requested in this study were justified and confirmed or influenced the management of paediatric patients, ultimately reducing the risk of complications and further treatment.

Advance care planning: the impact of Ceiling of Treatment plans in patients with Coordinate My Care

2018 ◽  
Vol 9 (3) ◽  
pp. 267-270 ◽  
Author(s):  
Helen Lucy Broadhurst ◽  
Joanne Droney ◽  
Tom Callender ◽  
Amanda Shaw ◽  
Julia Riley
Keyword(s):  
Care Home ◽  
Service Evaluation ◽  
Urgent Care ◽  
Free Text ◽  
Care Planning ◽  
Medical Interventions ◽  
Treatment Plans ◽  
Advance Care ◽  
The Impact ◽  
Resuscitation Status

ObjectivesThe aim of this evaluation is to describe the components and results of urgent care planning in Coordinate My Care (CMC), a digital clinical service for patients with life-limiting illness, for use if a patient is unable to make or express choices. Ceiling of treatment (CoT) plans were created detailing where the patient would like to receive their care and how aggressive medical interventions should be.MethodsA retrospective service evaluation was completed of all CMC records created between December 2015 and September 2016 (n=6854). CMC records were divided into two cohorts: those with a CoT plan and those without. The factors associated with these cohorts were reviewed including age, diagnosis, resuscitation status and preferences for place of death (PPD). Analysis of the non-mandatory free text section was carried out.ResultsTwo-thirds of patients had recorded decisions about CoT. Regardless of which CoT option was chosen, for most patients, PPD was home or care home. Patients with a CoT plan were more likely to have a documented resuscitation status. Patients with a CoT were more likely to die in their PPD (82%vs71%, OR 1.79, p<0.0001). A higher proportion of patients with a CoT decision died outside hospital.ConclusionThis analysis demonstrates that a substantial proportion of patients are willing to engage in urgent care planning. Three facets of urgent care planning identified include PPD, CoT and resuscitation status.

scholarly journals Effect of Obesity on Clinical Failure of Patients Treated with Beta-Lactams

2021 ◽  
Author(s):  
Nathan A Pinner ◽  
Natalie G Tapley ◽  
Katie E Barber ◽  
Kayla R Stover ◽  
Jamie L Wagner
Keyword(s):  
Treatment Failure ◽  
Clinical Outcomes ◽  
Hospital Length Of Stay ◽  
Source Control ◽  
Definitive Treatment ◽  
Therapeutic Drug ◽  
Obese Patients ◽  
Definitive Therapy ◽  
All Cause Mortality ◽  
The Impact

Abstract Background Altered pharmacokinetics in obese patients raise concerns over worse clinical outcomes. This study assessed whether obese patients receiving a beta-lactam (BL) have worse clinical outcomes compared to non-obese patients and to identify if therapeutic drug monitoring (TDM) may be beneficial. Methods This multi-center, retrospective cohort included hospitalized adults admitted from July 2015-July 2017 treated with a BL as definitive monotherapy against a Gram-negative bacilli for ≥72 hours. Patients were excluded if there was lack of source control or if polymicrobial infections required &gt;1 antibiotic for definitive therapy. Patients were classified based on body mass index (BMI): non-obese (BMI ≤29.9 kg/m 2) and obese (BMI ≥30.0 kg/m 2). The primary outcome was clinical treatment failure, and secondary were hospital length of stay (LOS), inpatient all-cause mortality, and 30-day all-cause readmission. Results There were 257 (43.6%) obese patients and 332 (56.4%) non-obese patients included. The most common infections were urinary (50.9%) and respiratory (31.4%). Definitive treatment was driven by 3 rd generation cephalosporins (46.9%) and cefepime (44.7%). Treatment failure occurred in 131 (51%) obese patients and 109 (32.8%) non-obese patients (p&lt;0.001). Obesity and respiratory source were independently associated with increased likelihood of treatment failure. Obese patients were hospitalized longer than non-obese patients (p=0.002), but no differences were found for all-cause mortality (p=0.117) or infection-related readmission (0=0.112). Conclusions Obese patients treated with BLs have higher rates of treatment failure and longer hospitalization periods than non-obese patients. Future studies are needed to assess the impact of TDM and specific dosing recommendations for targeted infection types.

scholarly journals Quality of Life following Chemoradiotherapy for Localized Muscle Invasive Bladder Carcinoma: A Systematic Review

2021 ◽  
pp. 1-13
Author(s):  
Ben-Max De Ruiter ◽  
Abel N. Keijzer ◽  
Maarten C.C.M. Hulshof ◽  
Adriaan D. Bins ◽  
Theo M. de Reijke ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sexual Function ◽  
Bladder Carcinoma ◽  
Bowel Function ◽  
Definitive Treatment ◽  
Cochrane Library ◽  
Social And Emotional ◽  
Muscle Invasive ◽  
The Impact

BACKGROUND: Health related Quality of Life (HRQoL) is an important factor regarding treatment for localized Muscle Invasive Bladder Carcinoma (MIBC), as it may affect choice of treatment. The impact of chemoradiotherapy (CRT) for MIBC on HRQoL has not yet been well-established. OBJECTIVE: To systematically evaluate evidence regarding HRQoL as assessed by validated questionnaires after definitive treatment with CRT for localized MIBC. METHODS: We performed a critical review of PubMed/MEDLINE, EMBASE, and the Cochrane Library in October 2020. Two reviewers independently screened articles for eligibility and assessed the methodological quality of the included articles using Joanna Briggs Institute critical appraisal tools. A narrative synthesis was undertaken. RESULTS: Of 579 articles identified, 11 studies were eligible for inclusion, including three RCTs and 8 non-randomized studies, reporting on HRQoL data for 606 CRT patients. Global health declined at End of treatment (EoT), and recovered 3 months following treatment. Physical function declined from baseline at EoT and recovered between 3 and 24 months and was maintained at 5 years follow up. CRT had little effect on social and emotional function in the short-term, but HRQoL results in the long-term were lower compared to the general population. Urinary function declined from baseline at EoT, but returned to baseline at 6 months following CRT. After initial decline in bowel function, a complete return to baseline occurred 4 years following treatment. The majority of studies assessing sexual function showed no to little effect on sexual function. CONCLUSIONS: HRQoL recovers to baseline within 3 months to 2 years in almost all domains. The amount of available evidence regarding HRQoL following CRT for MIBC is limited and the quality of evidence is low.

scholarly journals Multicriterial CNN based beam generation for robotic radiosurgery of the prostate

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Stefan Gerlach ◽  
Christoph Fürweger ◽  
Theresa Hofmann ◽  
Alexander Schlaefer
Keyword(s):  
Deep Learning ◽  
Treatment Planning ◽  
Treatment Plan ◽  
Plan Quality ◽  
New Approach ◽  
Beam Generation ◽  
Radiological Features ◽  
Improve Treatment ◽  
Robotic Radiosurgery ◽  
Treatment Plans

AbstractAlthough robotic radiosurgery offers a flexible arrangement of treatment beams, generating treatment plans is computationally challenging and a time consuming process for the planner. Furthermore, different clinical goals have to be considered during planning and generally different sets of beams correspond to different clinical goals. Typically, candidate beams sampled from a randomized heuristic form the basis for treatment planning. We propose a new approach to generate candidate beams based on deep learning using radiological features as well as the desired constraints. We demonstrate that candidate beams generated for specific clinical goals can improve treatment plan quality. Furthermore, we compare two approaches to include information about constraints in the prediction. Our results show that CNN generated beams can improve treatment plan quality for different clinical goals, increasing coverage from 91.2 to 96.8% for 3,000 candidate beams on average. When including the clinical goal in the training, coverage is improved by 1.1% points.

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