scholarly journals Frequency of Renal Dysfunction and its effects on outcomes after open heart surgery

2021 ◽  
Vol 37 (7) ◽  
Author(s):  
Taimur Asif Ali ◽  
Khuzaima Tariq ◽  
Areej Salim ◽  
Saulat Fatimi

Objectives: In this study we determined the frequency of renal dysfunction and its outcomes in terms of morbidity and mortality in patients who underwent open heart surgery at the Aga Khan University Hospital, Karachi, Pakistan. Methods: A total of 175 patients aged between 15-80 years having open heart Surgery(OHS) were included. Preoperative and postoperative serum creatinine (SCr) was noted and the glomerular filtration rate (GFR) calculated by Cockcroft-Gault equation. Their hospital course was charted and followed-up for 30-day. Results: The mean age and mean BMI were 58.1±12.6 years and 26.4±4.3 kg/m2 respectively. Females were 18.3%, out of which 51.4% hypertensive, 46.9% diabetics, 45.1% had dyslipidemia, 2.9% had preoperative renal dysfunction and 40% had moderate ejection fraction. On follow up, 30.3% developed postoperative renal dysfunction within 30-days after OHS with mean SCr and GFR as 1.6±0.7 and 56.9±24.5, respectively. In RD group more patients showed positive outcomes i.e. prolonged inotropic requirement (75.5% vs. 18%, p-value <0.005), diuretic infusion usage (47.2% vs. 3.3%, p-value <0.005), dialysis/renal replacement therapy (17% vs. 0%, p-value <0.005), requirement for prolonged ventilation (35.8% vs. 6.6%, p-value <0.005), prolonged ICU and hospital stay (15.4% vs. 1.6%, p-value <0.005 and 41.5% vs. 17.2%, p-value <0.005), sepsis (20.8% vs. 1.6%, p-value <0.005) and death (9.4% vs. 2.5%, p-value 0.05). Conclusion: Timely recognition of renal dysfunction, early renal replacement therapy, diuretics or dialysis and proper nutritional and inotropic support to maintain adequate hemostasis shows survival benefits. doi: https://doi.org/10.12669/pjms.37.7.3865 How to cite this:Ali TA, Tariq K, Salim A, Fatimi S. Frequency of Renal Dysfunction and its effects on outcomes after open heart surgery. Pak J Med Sci. 2021;37(7):---------. doi: https://doi.org/10.12669/pjms.37.7.3865 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

1996 ◽  
Vol 22 (12) ◽  
pp. 1418-1423
Author(s):  
L. B. Siegel ◽  
H. J. Dalton ◽  
J. H. Hertzog ◽  
R. A. Hopkins ◽  
R. L. Hannan ◽  
...  

2017 ◽  
Vol 35 (4) ◽  
pp. 285
Author(s):  
Phavinee Paorod ◽  
Weerapong Chidnok ◽  
Jarun Sayasathid

Objective: To investigate the effects of home-based cardiac rehabilitation program on exercise capacity using the six-minute walk test (6-MWT) in open heart surgery patients, Naresuan University Hospital.Material and Method: In a quasi-experimental study design, seventy patients who were diagnosed with heart diseases and received open heart surgery at Cardiac Center, Naresuan University Hospital were enrolled and collected data from October 2015 - September 2016 (n=70). The patients completed 8-12 weeks home-based cardiac rehabilitation program. The patients were performed the 6-MWT before hospital discharge, the first and second follow up time point. Data were expressed as average mean and chi-square test were used to determine the relationships among outcome parameters.Results: There was a significant within-group in 6-MWT distance after completed home-based cardiac rehabilitation program (377.0±69.0 meters) compared to before hospital discharge (209.0±62.0 meters) and the first follow up time point (4-8 weeks) (306.0±88.0 meters) (p-value<0.050).Conclusion: The 8-12 weeks home-based cardiac rehabilitation program exhibited significant positive effects on exercise capacity in open heart surgery patients, Naresuan University Hospital.


1994 ◽  
Vol 24 (6) ◽  
pp. 753
Author(s):  
Kyung Phill Suh ◽  
Joon Ryang Rho ◽  
Yong Jin Kim ◽  
Hyuk Ahn ◽  
Yung Kyoon Lee

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Ricardo L Levin ◽  
Marcela A Degrange ◽  
Rafael Porcile ◽  
Flavio Salvagio ◽  
Norberto Blanco ◽  
...  

Background: Patients with low ejection fraction (EF<25%) present high-risk of mortality and development of low output state (LOS) after cardiac surgery. The objective of this research was to evaluate the preoperative use of the calcium sensitizer Levosimendan (Levo) in patients with EF<25%, underwent open heart surgery. Thirty-day mortality and development of postoperative LOS were the primary end-points of the study. Methods: Patients with EF<25% and hemodynamic parameters of LOS (cardiac index<2.2 L/min/m2 and pulmonary artery occlusion pressure>15 mm Hg), underwent coronary bypass surgery between 12/01/2002 and 02/01/2007 were randomized to: preoperative infusion of Levo 0.1 mcg/Kg/min, 24 hours before surgery (Levo group-preoperative optimization), or placebo (Control group). LOS postoperative was defined for the same hemodynamic variables. A P value < 0.05 was considered significant Results: Two-hundred and twenty one patients fulfilled the inclusion criteria, being randomized 111 of them to Levo, and 110 patients to placebo. Both groups were comparable in their general and surgical characteristics. No withdrawal of Levo was required during the preoperative administration, with 8 patients showing hypotension episodes which was resolved with fluid infusions. There were not ventricular arrhythmias, supraventricular arrhythmias (with heart rate over 125) or preoperative ischemic events. The 30-day mortality was 3 patients in the Levo group (2.7%) versus 12 patients in the Control group (10.9%, P value 0.001, OR 0.23, IC95 0.05– 0.90). Seven patients in the Levo group developed postoperative LOS (6.3%) against 20 patients in the Control group (18.2%, P value <0.001, OR 0.30, IC95 0.11– 0.80) Conclusion: The preoperative optimization with Levosimendan reduced the operative mortality and the development of postoperative LOS in patients with EF<25% underwent open heart surgery. The infusion was safety no needing to withdraw it in any case. These findings could represent a new strategy to reduce the operative risk in this group of patients.:


2007 ◽  
Vol 5 (3) ◽  
pp. 0-0
Author(s):  
Vytautas Antanas Pronckus ◽  
Dobilas Barysas

Vytautas Antanas Pronckus, Dobilas BarysasVilniaus universiteto ligoninės Santariškių klinikų Širdies chirurgijos centras,Santariškių g. 2, LT-08661, VilniusEl paštas: [email protected] Įvadas / tikslas Gydant infekuotas žaizdas po širdies operacijų vis didesnę reikšmę įgauna gydymo trukmė, ligonio gyvensenos kokybė ir pasiekiamas kosmetinis efektas. Apsukinės siūlės naudojimas gali pagerinti ligonių savijautą, sumažinti gydomųjų procedūrų skaičių, pagreitinti žaizdos gijimą. Metodai Infekuotos žaizdos išplaunamos, jų kraštai atnaujinami, pašalinamos detritinės masės. Esant indikacijų, drenai paliekami priekiniame mediastinume ir (arba) virš krūtinkaulio. Minkštieji audiniai (fascijos, raumenys, poodis) susiuvami monofilamento apsukine monofilamento siūle 5–6 cm segmentais. Oda susiuvama intrakutanine monofilamento 4–5 cm ilgio segmentais. Tvarsčiai keičiami du kartus per dieną. Gydymas paprastai trunka 14 dienų. Rezultatai Šiuo būdu gydomos infekuotos žaizdos gijo greičiau, pakartotinai žaizdų revizuoti nereikėjo, gydomi ligoniai jautėsi geriau ir buvo pasiektas santykiškai geras kosmetinis efektas. Išvados Manome, kad toks infekuotos žaizdos po širdies operacijų gydymo būdas yra tinkamas ir klinikinėje praktikoje taikytinas dažniau. Pagrindiniai žodžiai: infekcija, gydymas Longitudinal running suture in treatment of infected wounds after heart surgery Vytautas Antanas Pronckus, Dobilas BarysasVilnius University Hospital „Santariškių klinikos“, Cardiac Surgery Centre,Santariškių str. 2, LT-08661, VilniusE-mail: [email protected] Background / objective The duration of treatment’s, patient’s quality of life and the cosmetic result of the treatment currently become increasingly important in the treatment of infected wounds after open heart surgery. Application of running suture may improve the quality of life, decrease the number of therapeutic procedures and facilitate recovery in these patients. Methods After washing and debridement of the wound, the sides of the wound are renewed. If necessary, the drains are left in anterior mediastinal space and / or above the sternum. Soft tissues (i. e. fascia, muscles and subcutaneous tissue) are sutured using running monofilament suture in 5–6 cm long segments. The skin is closed by means of intracutaneous monofilament suture (segments of 4–5 cm). The dressings are changed twice a day. The treatment usually lasts 14 days. Results While using this method, the wound healing was faster, the patients required no additional wound revisions, the quality of patient’s life was better and the treatment resulted in relatively improved cosmetic results. Conclusions We conclude that this method is appropriate for treatment of infected wounds after open heart surgery and might be applied more frequently. Key words: infection, treatment


2021 ◽  
Vol 5 (1) ◽  
pp. 01-12
Author(s):  
Abdul-Monim Mohammad Batiha ◽  
Ibtisam Al-Zaru ◽  
Majdee Saiah AL-Shaarani ◽  
Fadwa N Alhalaiqa

Despite significant advances in open heart surgery over the last two decades, postoperative pulmonary complications (PPCs) are considered the most important causes that contribute to patient morbidity, mortality and prolonged hospital stay. The ultimate goal of this paper was to investigate the risk factors which increasing the incidence rate of pulmonary complications after open heart surgery of Jordanian patients. A retrospective design using an existing coronary artery surgery database of adults (n = 200) who had undergone open heart surgery between August 2014 and July 2015 at a University Hospital in Jordan. A structured PPCs instrument was used to assess ‘PPCs risk factors assessment sheet’. According to the results, the proposed model provides a preliminary indication of risk factors placing open heart surgical patients at risk of PPCs. Determining patients who are at risk of developing PPC’s after cardiac surgeries are the first step towards its prevention. This reduces its burden in term of morbidity, mortality and cost.   Keywords: Jordan, open heart surgery, predictors, pulmonary complications, risk factors.


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