scholarly journals Estimation and human health risk assessment of organochlorine and organophosphate pesticide residues in raw milk collected in Kenya

F1000Research ◽  
2022 ◽  
Vol 11 ◽  
pp. 14
Author(s):  
Sheridan Wanjiku Philip ◽  
Vincent Madadi Odongo ◽  
Shem Oyoo Wandiga ◽  
Duke Gekonge Omayio ◽  
Mitchel Otieno Okumu

Background: This study determined the levels of organochlorine (OCPs) and organophosphate (OPPs) pesticide residues in cow milk from Kiambu and camel milk from Isiolo and Laikipia. The human dietary intake and the potential consumer health risks were also evaluated. Methods: In total, 90 cow and 82 camel milk samples were collected and analyzed using gas chromatography tandem mass spectroscopy to determine the levels of OCPs and OPPs. The levels were compared to the maximum residue limits (MRLs) established by the Codex Alimentarius (CA), EU Pesticides Database (EUPD), and the United States Department of Agriculture. The estimated daily intake and chronic hazard quotient (cHQ) of the milk were also calculated. Results: Cow milk from Kiambu was contaminated with 11/18 of the evaluated OCPs and 13/14 of the evaluated OPPs while camel milk from Isiolo was contaminated with 9/18 of the evaluated OCPs and 9/14 of the evaluated OPPs. Camel milk from Laikipia was contaminated with 11/18 of the evaluated OCPs and 11/14 of the evaluated OPPs. The mean heptachlor value in camel milk from Isiolo was above the EUPD MRLs. The mean value of heptachlor in Camel milk from Laikipia was above the CA and EUPD MRLs. The cHQs for Disulfoton, Fenamiphos, and Methacrifos in Cow milk were above 1 for adults and children. The cHQs for Fenchlorphous and Profenofos in Camel milk were above 1 for adults and children. The cHQs for α-endosulphan, β-endosulphan, dieldrin, and heptachlor in cow milk was above 1 for adults and children while the cHQs for heptachlor in camel milk was above 1 for adults and children. Conclusions: The potential health risks from chronic dietary intake of cow and camel milk in Kenya cannot be excluded. The routine monitoring of organophosphate and organochlorine pesticide levels in milk is recommended to minimize risks to human health.

2021 ◽  
Vol 71 (1) ◽  
Author(s):  
Trishala Gopikrishna ◽  
Harini Keerthana Suresh Kumar ◽  
Kumar Perumal ◽  
Elavarashi Elangovan

Abstract Purpose Fermented soybean foods (FSF) is popularly consumed in the South-East Asian countries. Bacillus species, a predominant microorganism present in these foods, have demonstrated beneficial and deleterious impacts on human health. These microorganisms produce bioactive compounds during fermentation that have beneficial impacts in improving human health. However, the health risks associated with FSF, food pathogens, biogenic amines (BAs) production, and late-onset anaphylaxis, remain a concern. The purpose of this review is to present an in-depth analysis of positive and negative impacts as a result of consumption of FSF along with the measures to alleviate health risks for human consumption. Methods This review was composed by scrutinizing contemporary literature of peer-reviewed publications related to Bacillus and FSF. Based on the results from academic journals, this review paper was categorized into FSF, role of Bacillus species in these foods, process of fermentation, beneficial, and adverse influence of these foods along with methods to improve food safety. Special emphasis was given to the potential benefits of bioactive compounds released during fermentation of soybean by Bacillus species. Results The nutritional and functional properties of FSF are well-appreciated, due to the release of peptides and mucilage, which have shown health benefits: in managing cardiac disease, gastric disease, cancer, allergies, hepatic disease, obesity, immune disorders, and especially microbial infections due to the presence of probiotic property, which is a potential alternative to antibiotics. Efficient interventions were established to mitigate pitfalls like the techniques to reduce BAs and food pathogens and by using a defined starter culture to improve the safety and quality of these foods. Conclusion Despite some of the detrimental effects produced by these foods, potential health benefits have been observed. Therefore, soybean foods fermented by Bacillus can be a promising food by integrating effective measures for maintaining safety and quality for human consumption. Further, in vivo analysis on the activity and dietary interventions of bioactive compounds among animal models and human volunteers are yet to be achieved which is essential to commercialize them for safe consumption by humans, especially immunocompromised patients.


2021 ◽  
Vol 8 (1) ◽  
pp. 1-5
Author(s):  
Nahla S El-Shenawy ◽  
Heba N Gad EL-Hak ◽  
Mahi A Ghobashy ◽  
Maha FM Soliman ◽  
Farida A Mansour ◽  
...  

Accumulation of heavy metals in fish is considered a critical problem for human health. Therefore, the study aimed to quantify the concentrations of iron (Fe), zinc (Zn), manganese (Mn), and lead (Pb) in Oreochromis niloticus and Clarias gariepinus from two areas in Al Sharqia governorate, Egypt, from September 2017 to August 2018. A human health risk assessment was conducted to evaluate the potential hazards associated with fish consumption. Metals concentrations (mg/kg dry weight) in muscles of catfish ranged 1.88-221.26 for Fe; 1.78-19.77 for Zn; BDL-238.51 for Mn; BDL-22.75 for Pb. In muscles of tilapia fish metals concentrations ranged 7.96-149.10 for Fe; 1.20-19.77 for Zn; BDL-230.82 for Mn; BDL-25.93 for Pb. Pb had Hazard quotients (HQs) which indicated potential health risks to tilapia consumers at both study areas and catfish consumers at the Faqous area. Fishermen were at higher risk compared to the other consumers.


Author(s):  
C. S. Okoye ◽  
C. E. Oguh ◽  
O. J. Umezinwa ◽  
C. C. Uzoefuna ◽  
B. C. Nwanguma ◽  
...  

Quantification of pesticide residues in retail samples of food is one way to determine the level of human exposure to these chemicals and hence their potential health hazards. The study was aimed at quantifying the level of some known pesticides in retail samples of Vigna unguiculata (L.) Walp. (Cowpea) from two cropping seasons. Five cultivars of cowpea from two different harvest seasons (2016/2017 and 2017/2018) were purchased from Ogige Market, Nsukka, Enugu State, Nigeria. The cowpeas were identified based on city/state where they were cultivated. Two foreign samples were also purchased from London, UK. The pesticide residues were determined using gas chromatography coupled with electron capturing detector (GC-ECD). The results showed that the retail samples of cowpea contained residues of one or more organochlorines and organophosphates. The levels of post-harvest pesticides, 2, 2-dichlorovinyl dimethyl phosphate (DDVP) in 2016/17 season (0.02 μg/g) exceeded the international permissible standards (0.01 μg/g). The levels of the pre-harvest pesticides, glyphosate was low in both seasons (0.01 μg/g) when compared to the international permissible standards (0.1 μg/g).  The DDVP was not detected in the two foreign samples. HCB (Hexachlorobenzene), α-HCH (alpha-Hexachlorocyclohexane), Chlorpyrifos, g-chlordane, t-nonachlor, p-p’-DDT (Dichlorodiphenyltrichloroethane), p-p’-DDE (Dichlorodiphenyldichlo-rowthylene), and p-p’-DDD (Dichlorodiphenyldichloroethane) were detected in the cowpea from two cropping seasons despite being banned from agricultural use. This could be due to the additional application of pesticides during storage of the cowpeas. The findings concludes that the levels of some of the residues exceeded the safety limits while some were below the safety limits, suggesting that some of samples of the cowpea were not safe for human consumption as bioaccumulation, persistence, and toxicity of these residues was likely to pose serious health risks to the consumers. Generally, cowpea from the 2016/17 season contained higher pesticide residues than those from the 2017/18 season.


Author(s):  
Gaukhar S. Konuspayeva

If gross composition of camel milk is roughly comparable to cow milk, fine composition shows significant differences explaining potential health benefit for regular consumers. The main particularities of camel milk are (1) better atherogenicity index thanks to its higher proportion of mono-unsaturated and polyunsaturated fatty acids compared to other milks, (2) different proportion of caseins than cow milk leading to difficult clotting, (3) lack of β-lactoglobulin, often responsible for cow milk allergy, (4) slightly higher concentration in antibacterial and immunity support proteins with higher bio-activity than in other milk, (5) presence of WAP (whey acidic protein) and PGRP (peptidoglycan-recognition protein) not available in cow milk, (6) probable efficient insulin for supporting better glycemia regulation, (7) better metabolization of lactose leading to lower intolerance in consumers, (8) richness in sodium and iron compared to other milks, and (9) contrasted values of vitamins (less vitamins B, high quantity of vitamins C and D). This chapter explores camel milk composition and nutritional value.


2019 ◽  
Vol 172 ◽  
pp. 511-521 ◽  
Author(s):  
Govinda Bhandari ◽  
Paul Zomer ◽  
Kishor Atreya ◽  
Hans G.J. Mol ◽  
Xiaomei Yang ◽  
...  

2015 ◽  
Vol 170 (1) ◽  
pp. 65-74 ◽  
Author(s):  
Abdel-Rahim H. A. Hassan ◽  
Mohamed M. A. Zeinhom ◽  
Mariam A. Abdel-Wahab ◽  
Mona H. Tolba

2017 ◽  
Vol 25 (2) ◽  
pp. 127-144
Author(s):  
Mohamed Nouri ◽  
Taoufik El Rasafi ◽  
Abdelmajid Haddioui

Abstract The concentrations of metals were determined in soil samples collected in Ait Ammar (Oued Zem, Morocco). The mean Cd, Cr, Cu, Fe, Pb and Zn contents in the mining topsoil samples were: 2.12, 135, 34.9, 214, 9.13 and 90.8 mg kg−1, respectively. Human health risks developed from metal ingestion, dermal absorption and inhalation of soils were also evaluated. For non-carcinogenic risks, united hazard index (HI) values for children surpassed the safe level (HI=1) for Cr (13.1). Values for HI in adults (1.74) also surpassed the safe level for Cr. The HI values for Pb and Cd for children were 0.69 and 0.68, respectively. Cancer risk due to Cr surpassed the tolerable range (1E-06 to1E-04) for children (1.05E-03) and for adults (1.42E-04). Cancer risks due to Pb and Cd were within acceptable ranges for both children and adults. Furthermore, oral ingestion of soil particles contributed more highly to both carcinogenic and non-carcinogenic risk from Cr than either dermal absorption or inhalation in both children and adults.


2017 ◽  
Vol 7 (14) ◽  
pp. 30-36 ◽  
Author(s):  
Md. Shakhaoat Hossain ◽  
Prantik Roy ◽  
Monira Islam ◽  
Md. Alamgir Zaman Chowdhury ◽  
Zeenath Fardous ◽  
...  

Background. Heavy metals contamination of food is a serious threat. Long term exposure may lead to human health risks. Poultry and eggs are a major source of protein, but if contaminated by heavy metals, have the potential to lead to detrimental effects on human health. Objectives. The objective of this study is to determine chromium concentrations in poultry meat (flesh and liver) and eggs collected from poultry farms in Dhaka, Bangladesh, to calculate the daily intake of chromium from the consumption of poultry meat and eggs for adults, and to evaluate their potential health risk by calculating the target hazard quotients (THQ). Methods. All samples of poultry feed, meat (flesh and liver) and eggs were analyzed by a graphite furnace atomic absorption spectrometer (AAS) (GFA- EX- 7i Shimadju, Japan). Results. Chromium concentrations were recorded in the range of not detected (ND) to 1.3926±0.0010 mg kg−1 and 0.0678±0.0001 mg kg−1 to 1.3764±0.0009 mg kg−1 in the liver of broiler and layer chickens, respectively. Chromium concentrations were determined in the range of 0.069±1.0004 mgkg−1 to 2.0746±0.0021 mg kg−1 and 0.0362±0.0002 mg kg−1 to 1.2752±0.0014 mg kg−1 in the flesh of broiler and layer chicken, respectively. The mean concentration of chromium in eggs was 0.2174−1.08 mg kg.−1 The highest concentration of chromium 2.4196±0.0019 mg kg−1 was found in egg yolk. Target hazard quotients values in all poultry flesh, liver and eggs samples were less than one, indicating no potential health risks to consumers. Conclusions. The estimated daily intake values of chromium were below the threshold limit. Thus, our results indicate that no adverse health effects are expected as a resultof ingestion of chicken fed with tannery waste. Competing Interests. The authors declare no competing financial interests. Ethics Approval: This study was approved by the Biosafety, Biosecurity & Ethical Committee of Jahangirnagar University.


2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Minbale Aschale ◽  
Yilma Sileshi ◽  
Mary Kelly-Quinn

Abstract Background Vegetables grown at contaminated sites can take up and accumulate toxic and potentially toxic elements at concentrations that are toxic to human health. The present study determined the levels of potentially toxic elements/PTEs in irrigation water, soil and vegetable samples grown along contaminated river and assessed the potential health risks to consumers. Results The average concentrations of Mn, Sr and Cr in the irrigation water were higher than the international guideline values. The levels of As, Cr, B and Ni in most of the farm soils were also found to be higher than the guideline values. Other PTEs, although not exceeding the recommended limits were relatively high in the soil and water samples. The study also revealed that the mean levels of Cr, Cd and Fe in most vegetables were higher than the maximum recommended limits. Swiss chard was maximally contaminated with PTEs followed by lettuce, cabbage, Ethiopian kale, carrot and potato. Hence, frequent consumption of lettuce and Swiss chard may cause serious health risks to consumers. Conclusion The levels of many elements were varied with location, suggesting localized inputs of the various contaminants related to industrial and other activities that generate wastewater.


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