scholarly journals The effectiveness of community neurorehabilitation for persons with an acquired brain injury: protocol for a systematic review

2021 ◽  
Vol 4 ◽  
pp. 25
Author(s):  
Eileen Mitchell ◽  
Nicola Philips ◽  
Elayne Ahern ◽  
Grainne McGettrick ◽  
David Mockler ◽  
...  
Keyword(s):  
Systematic Review ◽  
Brain Injury ◽  
Acquired Brain Injury ◽  
Inpatient Rehabilitation ◽  
Clinical Effectiveness ◽  
Evidence Base ◽  
Service Development ◽  
Rehabilitation Services ◽  
Randomised Controlled ◽  
The Impact

Background: Acquired brain injury (ABI) refers to any type of brain damage after birth.  ABI from either traumatic or non-traumatic origin is a leading cause of death and long-term disability globally.  The impact of an ABI can be cognitive and/ or physical, greatly affecting their ability to function independently.  With a lack of specialist inpatient rehabilitation facilities and services many of these survivors reside within the community either alone, with family or in residential facilities.  Up-to-date evidence is required to indicate which forms of community rehabilitation are most effective in improving cognitive and physical outcomes for survivors. This systematic review aims to explore the clinical effectiveness of community neuro-rehabilitation services for persons living with an ABI. Methods: A systematic review of relevant electronic databases will be undertaken to identify eligible published randomised controlled trials.  The PRISMA statement will be used to guide the systematic review.  From running the initial search, we aim to submit the paper for publishing within 6 months.  This process will be completed using Covidence software.  Two reviewers will independently screen the search results and select studies using pre-defined selection criteria, extract data from and assess risk of bias for selected studies.     Discussion: This systematic review will aim to explore the clinical effectiveness of community neuro-rehabilitation services for persons with an ABI.  It plans to review and synthesize the current best available evidence base. A goal of this study is to positively inform ongoing service development within a quality framework. Systematic review registration: PROSPERO CRD42020148604 (26/02/2020)

scholarly journals The Effectiveness of Community Neurorehabilitation for Persons with an Acquired Brain Injury: Protocol for a Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Nicola Phillips ◽  
Elayne Ahern ◽  
David Mockler ◽  
Grainne McGettrick ◽  
Kyle Fitzpatrick ◽  
...  
Keyword(s):  
Systematic Review ◽  
Brain Injury ◽  
Meta Analysis ◽  
Acquired Brain Injury ◽  
Inpatient Rehabilitation ◽  
Clinical Effectiveness ◽  
Evidence Base ◽  
Service Development ◽  
Randomised Controlled ◽  
The Impact

Abstract Background Acquired Brain Injury (ABI) refers to any type of brain damage after birth. ABI from either traumatic or non-traumatic origin is a leading cause of death and long-term disability globally. The impact of an ABI can be cognitive and/ or physical greatly affecting their ability to function independently. With a lack of specialist inpatient rehabilitation facilities and services many of these survivors reside within the community either alone, with family or in residential facilities. Up-to-date evidence is required to indicate which forms of community rehabilitation are most effective in improving cognitive and physical outcomes for survivors. This systematic review aims to explore the clinical effectiveness of community neurorehabilitation services for persons living with an ABI. Methods A systematic review of relevant electronic databases will be undertaken to identify eligible published randomised controlled trials. The PRISMA statement will be used to guide the systematic review. From running the initial search, we aim to submit the paper for publishing within 6 months. This process will be completed using Covidence software. Two reviewers will independently screen the search results and select studies using pre-defined selection criteria, extract data from and assess risk of bias for selected studies. Discussion This systematic review will aim to explore the clinical effectiveness of community neuro-rehabilitation services for persons with an ABI. It plans to review and synthesize the current best available evidence base. A goal of this study is to positively inform ongoing service development within a quality framework. Systematic review registration CRD: CRD42020148604

OP66 Tumor Profiling Tests In Early Breast Cancer: A Systematic Review

2018 ◽  
Vol 34 (S1) ◽  
pp. 24-24
Author(s):  
Susan Harnan ◽  
Katy Cooper ◽  
John Stevens ◽  
Ruth Wong ◽  
Paul Tappenden ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Clinical Effectiveness ◽  
Evidence Base ◽  
Risk Of Bias ◽  
Prognostic Information ◽  
Post Test ◽  
The Impact ◽  
Risk Of Relapse ◽  
Tumor Profiling

Introduction:Tumor profiling tests can help to identify whether women with breast cancer need chemotherapy due to their risk of relapse, and some may be able to predict benefit from chemotherapy. We focused on four genetic tests: Oncotype DX (O-DX), MammaPrint (MMP), EndoPredict and Prosigna, and one immunohistochemistry test, IHC4, for the National Institute of Health and Care Excellence as part of their Diagnostic Appraisal Programme.Methods:A systematic review was undertaken, including searching of nine databases in February 2017 plus other sources including a previous review published in 2013. The review included studies assessing clinical effectiveness of the five tumor profiling tests, with or without clinicopathological factors, to guide decisions about adjuvant chemotherapy in people with ER-positive, HER-2 negative, Stage I-II cancer with 0 to 3 positive lymph nodes (LN). The PROBAST tool and Cochrane risk of bias tools were used to assess risk of bias.Results:A total of 153 studies were included; the strength of evidence base for individual tests was varied. Results suggest all tests are prognostic for risk of relapse, though results were more varied in LN positive (+) patients than in LN negative (0) patients. Evidence was limited about whether tests can predict benefit from chemotherapy (available for MMP and O-DX only). Studies that assessed the impact of the tests on clinical decisions indicate that the net change in chemotherapy recommendations or decisions pre-/post-test ranged from an increase of one percent to a decrease of 23 percent among UK studies, and a decrease of zero percent to 64 percent across European studies.Conclusions:The studies included in the review suggest that all of the tests can provide prognostic information on the risk of relapse; however results were more varied in LN+ patients than in LN0 patients. There is limited and varying evidence for prediction of chemotherapy benefit.

Organic eating disorders of pica, hperphagia, and severe food restriction: Presentation and prevalence after acquired brain injury

2011 ◽  
Vol 26 (S2) ◽  
pp. 715-715
Author(s):  
R. Faruqui ◽  
K. El-Kadi ◽  
A. Rowell
Keyword(s):  
Systematic Review ◽  
Eating Disorders ◽  
Brain Injury ◽  
Food Restriction ◽  
Grey Literature ◽  
Case Series ◽  
Acquired Brain Injury ◽  
Classification Systems ◽  
Disease Classification ◽  
Service Development

IntroductionPersistent Hyperphagia, Pica, and Severe Food Restriction are rare but potentially life threatening complications following acquired brain injury. These disorders are not formally coded in disease classification systems though do present with significant management challenges in both inpatient and outpatient settings.ObjectivesTo inform treatment and management strategies and service development for complex neuropsychiatric conditionsAimsTo study presentation and prevalence of organic eating disorders following acquired brain injury.MethodsSystematic review of medical literature on Medline, PsychInfo, CINAHL, Embase, Cochrane database of systematic reviews, using terms eating disorders, organic eating disorders, binge eating, bulimia, anorexia nervosa, atypical eating disorders, food restriction, pica, head injury, acquired brain injury, traumatic brain injury.Service consultations and identification of grey literatureResultsSystematic review identified case reports, case series, and case studies relevant to these disorders. It also identified lack of research in this area and absence of well structured longitudinal studies that can identify true prevalence in a representative sample. Persistent Hyperphagia has been reported in 2–3% of adult cases requiring inpatient post acute rehabilitation. Pica has been reported in young children after acquired brain injury only. Two reports identified this condition in post neurosurgery period. Severe food restriction, at times also described as atypical anorexia, has been reported following acquired brain injury. However, it remains rather difficult to estimate prevalence in different patient populations.ConclusionsOrganic eating disorders present with significant levels of challenges in patient management and do carry identifiable mortality risk.

Play-based interventions improve physical function for people with adult-acquired brain injury: a systematic review and meta-analysis of randomised controlled trials

2016 ◽  
Vol 31 (2) ◽  
pp. 145-157 ◽  
Author(s):  
Nicola Saywell ◽  
Nick Taylor ◽  
Emma Rodgers ◽  
Luke Skinner ◽  
Mark Boocock
Keyword(s):  
Systematic Review ◽  
Brain Injury ◽  
Physical Function ◽  
Randomised Controlled Trials ◽  
Meta Analysis ◽  
Acquired Brain Injury ◽  
Controlled Trials ◽  
Traditional Therapy ◽  
Functional Outcome Measures ◽  
Randomised Controlled

Objective: To undertake a systematic review and meta-analysis of the effectiveness of play-based interventions compared to traditional therapy in rehabilitation of adults with adult-acquired brain injury. Data sources: The search was performed using Medline; Cinahl Plus; Health Source (Nursing/Academic Edition); Psychology and behavioural sciences collection; Biomedical reference collection (basic). Review methods: Studies included were randomised controlled trials that investigated the effect of play-based interventions on physical function of adults with adult acquired brain injury. Two independent reviewers identified eligible studies and assessed methodological quality using a modified Downs and Black. Meta-analysis compared standardised differences in means, to determine effect sizes for grouped functional outcome measures. The GRADE scoring system was used to determine the level of clinical evidence. Results: Thirty studies met the inclusion criteria, 13 were considered high quality and 17 moderate quality. Studies predominantly involved post-stroke participants, with only three studies including participants with traumatic brain injury. When compared to traditional therapy, dose-matched studies of play-based interventions showed a significant effect on independence (Effect size (ES) = 0.6) and physical performance (ES = 0.43), as measured using the Fugl –Meyer. For non-dose matched studies, play-based interventions showed a significant improvement for balance (ES = 0.76) compared with traditional therapy. In all studies that measured participant enjoyment, play-based therapy was rated as more enjoyable than traditional therapy. Conclusion: Play-based interventions for people with adult acquired brain injury are more effective in improving balance and independence, which may be due to them being more enjoyable than traditional therapy.

scholarly journals Systematic review of clinical practice guidelines to identify recommendations for rehabilitation after stroke and other acquired brain injuries

BMJ Open ◽  
2018 ◽  
Vol 8 (2) ◽  
pp. e018791 ◽  
Author(s):  
Laura Jolliffe ◽  
Natasha A Lannin ◽  
Dominique A Cadilhac ◽  
Tammy Hoffmann
Keyword(s):  
Systematic Review ◽  
Clinical Practice ◽  
Brain Injury ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Brain Injuries ◽  
Acquired Brain Injury ◽  
Inpatient Rehabilitation ◽  
Agree Ii ◽  
Registration Number

ObjectivesRehabilitation clinical practice guidelines (CPGs) contain recommendation statements aimed at optimising care for adults with stroke and other brain injury. The aim of this study was to determine the quality, scope and consistency of CPG recommendations for rehabilitation covering the acquired brain injury populations.DesignSystematic review.InterventionsIncluded CPGs contained recommendations for inpatient rehabilitation or community rehabilitation for adults with an acquired brain injury diagnosis (stroke, traumatic or other non-progressive acquired brain impairments). Electronic databases (n=2), guideline organisations (n=4) and websites of professional societies (n=17) were searched up to November 2017. Two independent reviewers used the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument, and textual syntheses were used to appraise and compare recommendations.ResultsFrom 427 papers screened, 20 guidelines met the inclusion criteria. Only three guidelines were rated high (>75%) across all domains of AGREE-II; highest rated domains were ‘scope and purpose’ (85.1, SD 18.3) and ‘clarity’ (76.2%, SD 20.5). Recommendations for assessment and for motor therapies were most commonly reported, however, varied in the level of detail across guidelines.ConclusionRehabilitation CPGs were consistent in scope, suggesting little difference in rehabilitation approaches between vascular and traumatic brain injury. There was, however, variability in included studies and methodological quality.PROSPERO registration numberCRD42016026936.

scholarly journals Publisher Correction to: BRAINSTORMING: A study protocol for a randomised double-blind clinical trial to assess the impact of concurrent brain stimulation (tDCS) and working memory training on cognitive performance in Acquired Brain Injury (ABI)

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Sara Assecondi ◽  
Rong Hu ◽  
Gail Eskes ◽  
Michelle Read ◽  
Chris Griffiths ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Working Memory ◽  
Brain Injury ◽  
Cognitive Performance ◽  
Acquired Brain Injury ◽  
Working Memory Training ◽  
Memory Training ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
The Impact

Following publication of the original article [1], the authors flagged that the article had published with the Acknowledgements erroneously excluded from the declarations at the end of the article.

Patient inclusion in goal setting during early inpatient rehabilitation after acquired brain injury

2011 ◽  
Vol 26 (2) ◽  
pp. 165-173 ◽  
Author(s):  
Catherine Dalton ◽  
Rachel Farrell ◽  
Annette De Souza ◽  
Evelyn Wujanto ◽  
Ann McKenna-Slade ◽  
...  
Keyword(s):  
Brain Injury ◽  
Goal Setting ◽  
Acquired Brain Injury ◽  
Inpatient Rehabilitation
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