Hyperthermia for deep seated tumours – possibilities of heating with capacitive devices

The review examines the general principles of capacitive electromagnetic hyperthermia (EMHT), the distribution of electromagnetic energy in various experimental models and in patients’ tumors, the design features of applicators from various capacitive hyperthermic systems and their role in achieving hyperthermic mode in tumors of deep localization. In classical capacitive EMHT, the main obstacle in achieving the required temperature in such tumors is overheating of the subcutaneous fatty tissue under the electrodes. For some capacitive hyperthermic systems, the heating of adipose tissues is enhanced due to the fact that the applicator design does not conform to certain technical requirements. In capacitive EMHT at frequencies of 8–13.56 MHz, obtaining the minimum hyperthermic mode is possible with output powers of 500–800 W, maximum – 1000–1200 W and above. The results of the use of various hyperthermic capacitive systems in patients with malignant tumors of internal organs are analyzed.

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Percentage of subcutaneous fatty tissue as an indicator of the physical status of volleyball players

Slovak Journal of Sport Science ◽

10.24040/sjss.2021.7.1.64-74 ◽

2021 ◽

Vol 7 (1) ◽

pp. 64-74

Author(s):

Ratko Pavlovič ◽

Vladan Savič ◽

Nikola Radulovič

Keyword(s):

Fatty Tissue ◽

Physical Status ◽

Subcutaneous Fatty Tissue ◽

Volleyball Players

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Soft Tissue Sarcomas of Extremities - MRI Role in the Diagnostic Evaluation

Romanian Journal of Orthopaedic Surgery and Traumatology ◽

10.2478/rojost-2018-0056 ◽

2018 ◽

Vol 1 (Supplement) ◽

pp. 45

Author(s):

A.M. Bratu ◽

I.A. Sălcianu ◽

C. Zaharia ◽

G. Iana ◽

A.N. Marinescu

Keyword(s):

Soft Tissue ◽

Malignant Tumors ◽

Soft Tissue Sarcomas ◽

Oblique Muscle ◽

Special Importance ◽

Fatty Tissue ◽

Anatomical Structures ◽

Bony Pelvis ◽

Female Predominance ◽

The Relationship

Abstract Introduction. Soft tissue sarcomas (STS) are rare entities of soft tissue cancers. Their incidence is low, of only 1% of the malignant tumors. In terms of localization, most of the STS affect the extremities, and their incidence is much higher in children than in adults. Material and method. The present paper is a retrospective study that includes tumors with lower limb localizations, including the bony pelvis, over a 3-year period (2013-2016). The study group consisted of 29 patients who, following the MRI examination, were diagnosed with softtissue tumors. Of the 29 patients, 17 patients had a MRI (magnetic resonance imaging) and an anatomopathological diagnosis of leiomyosarcoma. The location of the tumor, its characteristics, and the relationship with the adjacent anatomical structures were analyzed in all cases. Results. The ages of the final group of 17 patients ranged between 28 and 84 years, with female predominance. In terms of localization, one showed a muscle tumor in the pelvis, namely left oblique muscle, other cases being located in the thigh and knee. A special importance was given to the superficial and profound location. In 5 cases, the tumor was localized in subcutaneous fatty tissue, thus superficial. In terms of the contours of the tumor, well-defined margins were present in 11 cases, and poorly defined contour in 6 cases. Regarding the size, the leiomyosarcomas in our study had dimensions between 5.2 cm and 18 cm, and their structure was inhomogeneous, with the presence of necrosis and calcifications. Necrosis was found in 14 cases, and calcifications were present in 68%, being more frequent than necrosis. Except for the necrotic areas, the contrast enhancement was intense. Conclusions. Although the diagnosis is always histopathological, the MRI plays an important role in defining a precise localization and tumor characteristics.

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Positional differences in anthropometric characteristics of the Croatian U18 female field handball players

Kinesiology ◽

10.26582/k.52.1.10 ◽

2020 ◽

Vol 52 (1) ◽

pp. 124-133

Author(s):

Dinko Vuleta ◽

Lidija Bojić-Ćaćić ◽

Dragan Milanović ◽

Marjeta Mišigoj Duraković ◽

Dražan Dizdar

Keyword(s):

Dietary Habits ◽

Selection Process ◽

Fatty Tissue ◽

Fat Percentage ◽

Anthropometric Measures ◽

Anthropometric Characteristics ◽

Subcutaneous Fatty Tissue ◽

Training Programmes ◽

Almost All ◽

Game Performance

The aim of the study was to analyze positional differences in anthropometric characteristics of 48 Croatian selected female handball juniors (average age 18.43 years) who played in three positions: backs (B; n=19), wings (W; n=7) and pivots (P; n=6). Twenty-four anthropometric measures, defining the four latent morphological dimensions, were used. Globally, significant differences were revealed by means of ANOVA in 11 morphological measures (7 at p≤.01 and 4 at p≤.05) between the three groups of female juniors with no significant differences in longitudinal dimensions. Only one significant positional difference was found between pivots and backs (in the lower leg skinfold in favour of pivots suggesting a higher body fat percentage. Between wings and pivots no significant differences were found in longitudinal body dimensions; however, the measures of skeletal transversality, voluminosity and partially of fatty tissue (two variables) corroborated the fundamental difference between these two positions: pivotsʼ body built was more robust. No significant differences were found in longitudinal and almost all transversal measures between backs and wings; however, the differences in body voluminosity (all in favour of backs) were probably due to the selection process. In the juniorsʼ somatotype (3.72‒3.49‒2.32), endomorph and mesomorph components were predominant over the ectomorph component, in which the lowest values were obtained from the players in all the three positions. It is of outmost importance that handball practitioners should work on the reduction of players’ percentage of subcutaneous fatty tissue and on the enhancement of the portion of active muscle mass in their body composition by the implementation of quality sports training programmes and changes in dietary habits if better game performance and sports achievements of the Croatian junior female handball players are expected.

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Detection and volume estimation of artificial hematomas in the subcutaneous fatty tissue: comparison of different MR sequences at 3.0 T

Forensic Science Medicine and Pathology ◽

10.1007/s12024-017-9847-8 ◽

2017 ◽

Vol 13 (2) ◽

pp. 135-144

Author(s):

Kathrin Ogris ◽

Andreas Petrovic ◽

Sylvia Scheicher ◽

Hanna Sprenger ◽

Martin Urschler ◽

...

Keyword(s):

Volume Estimation ◽

Fatty Tissue ◽

Subcutaneous Fatty Tissue ◽

3.0 T ◽

Mr Sequences

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Pasture type in relation to live-weight gain, carcass composition, iodine nutrition and some rumen characteristics of sheep II. Carcass composition and the non-carcass components of live weight

The Journal of Agricultural Science ◽

10.1017/s002185960000592x ◽

1963 ◽

Vol 61 (2) ◽

pp. 191-195 ◽

Cited By ~ 12

Author(s):

R. A. Barton ◽

M. J. Ulyatt

Keyword(s):

White Clover ◽

Live Weight ◽

Carcass Composition ◽

Fatty Tissue ◽

Internal Organs ◽

Iodine Nutrition ◽

Rye Grass ◽

Short Rotation ◽

Mesenteric Fat ◽

Omental Fat

1. The results of two trials with Romney ewes grazed on perennial rye-grass (P), perennial rye-grass with white clover (P + C), short-rotation rye-grass (S) and short-rotation rye-grass with white clover (S + C) are reported. Chemical and dissection analyses of their carcasses were made and the weights of certain internal organs were obtained.2. It was found that the sheep grazed on the P plots had the lightest carcasses (56·2 and 40·9 lb. in trials I and II, respectively), followed by those on the P + C (70·2 and 59·2 lb.), by those on S (74·7 and 61·2 lb.) and the heaviest carcasses were yielded by sheep from the S + C plots (81·5 and 69·1 lb., respectively).3. The weights of dissectible fatty tissue and chemical fat of the carcasses were related to the carcass weights of the different groups of sheep; the group with the lightest carcass weight had the least fat. The other components of the carcass (protein, water and ash) followed the order for group mean carcass weights except that the S carcasses in trial II had slightly less water, protein and ash than the P + C carcasses. The percentage chemical fat of the S carcasses in trial I was also lower than the P + C carcasses.4. In general, the non-carcass components of live weight (head, feet, skin, liver, mesenteric fat, omental fat, kidneys, stomach empty, and intestines empty) all followed the same pattern of increasing weight (P < P + C < S < S + C).

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IN VITRO STUDIES ON ENZYMATIC CLEAVAGE OF STEROID ESTERS IN THE FEMALE ORGANISM

Acta Endocrinologica ◽

10.1530/acta.0.0810839 ◽

1976 ◽

Vol 81 (4) ◽

pp. 839-853 ◽

Cited By ~ 5

Author(s):

Otto Bellmann ◽

Hans-Jürgen Duhme ◽

Erich Gerhards

Keyword(s):

Water Solubility ◽

The Body ◽

Short Chain ◽

Human Myometrium ◽

Vaginal Mucosa ◽

Fatty Tissue ◽

Enzymatic Cleavage ◽

Cleavage Rate ◽

Subcutaneous Fatty Tissue ◽

Long Chain

ABSTRACT The decreasing water-solubility of steroid esters concomitant with increasing chain length of monocarboxylic acids provides a prolonged therapeutic effect of the steroid. Whether a slow release of the steroid from an oily depot in the muscle or a secondary storage of the ester in the body fat ("deep compartment") are responsible for this prolonged action, is open to discussion. The aim of this study was to investigate the steroid ester cleaving enzyme activity of human subcutaneous fatty tissue. The following steroid esters were investigated: Testosterone acetate and oenanthate, metenolone acetate and oenanthate, norethisterone acetate and oenanthate, dehydroepiandrosterone acetate and oenanthate, fluocortolone acetate and caproate. In the 10 000 x g supernatant phase of the female subcutaneous fatty tissue the rate of enzymatic cleavage of the long-chain oenanthates was considerably greater than that of the corresponding short-chain steroid esters. The nature and position of the ester group in the steroid molecule exhibited a marked effect on the rate of enzymatic cleavage of steroid esters. The cleavage rate of long- and short-chain steroid esters in human myometrium and endometrium resembled that in the fatty tissue. On the other hand, the gastric mucosa, rectus musculature, placenta and vaginal mucosa split the short-chain steroid esters more rapidly than the long-chain esters. The marked differences in the relation of the cleavage rate of long- and short-chain steroid esters in the various tissues allow the assumption that long- and short-chain steroid esters are cleaved by different enzymes.

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