scholarly journals The multipte-factor technogenic environmental pollution as risk factor of formation of cytogenetic violations at the population.

2014 ◽  
Vol 2014 (2) ◽  
pp. 155-160
Author(s):  
Антон Корсаков ◽  
Anton Korsakov
Keyword(s):  
Risk Factor ◽  
Environmental Pollution ◽  
Additive Effects ◽  
Radiation Factor ◽  
Total Level

Possibility of application of micronuclear dough in a bukkal epithelium is considered when comparing chemical, radiation and combined radiochemical pollution of the environment. At the combined influence of a chemical and radiation factor by authors possible manifestation, both additive effects, and a sinergizm and inhibition is revealed. The conclusion is drawn that cytogenetic characteristics of a bukkal epithelium can be used as "the biological dosimeter" total level of environmental pollution.

scholarly journals P2.10-09 Environmental Pollution in the City of Mexico as a Risk Factor for Lung Cancer and Its Prognostic Impact

2019 ◽  
Vol 14 (10) ◽  
pp. S788
Author(s):  
O. Macedo-Perez ◽  
I. Lyra Gonzalez ◽  
L. Bornstein ◽  
J. Castellanos ◽  
K. Campos-Peralta ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Risk Factor ◽  
Environmental Pollution ◽  
Prognostic Impact ◽  
The City

scholarly journals BANK1is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects withIRF5andSTAT4

2009 ◽  
Vol 60 (11) ◽  
pp. 3447-3454 ◽  
Author(s):  
P. Dieudé ◽  
J. Wipff ◽  
M. Guedj ◽  
B. Ruiz ◽  
I. Melchers ◽  
...  
Keyword(s):  
Risk Factor ◽  
Systemic Sclerosis ◽  
Genetic Risk ◽  
Genetic Risk Factor ◽  
Additive Effects ◽  
Diffuse Cutaneous Systemic Sclerosis

scholarly journals Post-war environmental pollution as a risk factor of congenital disorders in Iraq: A study review

2019 ◽  
Vol 2 (1) ◽  
pp. 1-13
Author(s):  
Muna Al-Hamdany
Keyword(s):  
Risk Factor ◽  
Environmental Pollution ◽  
Developmental Disorders ◽  
Chemical Constituents ◽  
Depleted Uranium ◽  
Teaching Hospitals ◽  
Congenital Defects ◽  
Congenital Disorders ◽  
Scientific Publications ◽  
Post War

Background: Several years of war with the recent terrorist conflicts have cumulatively affected Iraq’s land, air, water, and health infrastructure, and a substantial rise in the incidence of congenital defects has been reported in the period following the Gulf War in 1991, which was principally accredited to the environmental contamination by depleted uranium. Aim: The aim is to review some published works of literature that are specifically concerned with environmental pollution after the war in Iraq as a possible risk factor for developmental disorders. Patients and Methods: In addition to the published articles, this review includes a direct descriptive data of congenital anomalies, which was obtained from Al-Khansaa, Al-Salaam, Al-Batool Teaching Hospitals of Obstetrics and Gynecology, and General Mosul Hospital in Mosul city over a period of 12 months, starting from October 2017 to October 2018. Results: All of the research related to this topic were discussed, and most of them revealed that a higher incidence of congenital disorders was detected among people exposed directly or indirectly to post-war environmental pollution by depleted uranium (DU) and other chemical constituents. From the analysis of the scientific publications, we observed that Basrah, Baghdad, Falluja, Mosul and Al-Anbar are predominantly affected by war contamination. The study revealed that there were 317 cases of birth defects out of the 44,372 newborns delivered over a period of one year after war in Mosul; thus, the overall percentage of congenital disorders was 0.71%, and defects of the nervous system were the most prominent, among which anencephaly was the predominant condition. The highest percentage of anomalies was detected in the maternal age of 21–26 and more in female newborns. Conclusion: We must decrease parental exposure to the possible teratogens through prenatal counseling and public education about the penalties of environmental pollution in order to arrange practical guidelines for public health and to alleviate the outcome of pregnancy. Keywords: pollution, congenital, post-war,environmental, review

scholarly journals Variability of risk factors and diabetes complications

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Antonio Ceriello ◽  
Francesco Prattichizzo
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Quality Of Care ◽  
Diabetes Complications ◽  
Plasma Lipids ◽  
Glucose Variability ◽  
The Other ◽  
Additive Effects ◽  
Normal Range

AbstractSeveral studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body weight, and serum uric acid, might play a role in the development of diabetes complications. Moreover, the variability of each risk factor, when contemporarily present, may have additive effects. However, the question is whether variability is causal or a marker. Evidence shows that the quality of care and the attainment of the target impact on the variability of all risk factors. On the other hand, for some of them causality may be considered. Although specific studies are still lacking, it should be useful checking the variability of a risk factor, together with its magnitude out of the normal range, in clinical practice. This can lead to an improvement of the quality of care, which, in turn, could further hesitate in an improvement of risk factors variability.

Parental representations of melancholic and non-melancholic depressives: examining for specificity to depressive type and for evidence of additive effects

1992 ◽  
Vol 22 (3) ◽  
pp. 657-665 ◽  
Author(s):  
Gordon Parker ◽  
Dusan Hadzi-Pavlovic
Keyword(s):  
Risk Factor ◽  
Depressive Disorders ◽  
The Other ◽  
Additive Effects ◽  
Parental Style ◽  
Melancholic Depression ◽  
Parental Representations ◽  
Parental Styles ◽  
Specificity Effect ◽  
Current Sample

SynopsisSeveral studies have suggested that ‘anomalous parenting’, as measured by the Parental Bonding Instrument (PBI), may be a differential risk factor to subsequent depression in adulthood – being irrelevant to melancholia but over-represented in non-melancholic depressive disorders. Such a ‘specificity’ effect is confirmed in our current sample of 65 melancholic and 84 non-melancholic depressed patients. Secondly, we examine the risk to depression effected by exposure to one parent with an anomalous parental style, and the extent to which that risk is modified by characteristics of the other parent. We find clear evidence of additive effects with the risk to non-melancholic depression being raised by exposure to ‘anomalous parenting’ from two parents. Of the varying parental styles measured by the PBI, low parental care from both parents provided the highest risk to non-melancholic depression (being 4–7 time higher in one sample and 13–27 times higher in the other).

Identification of Pulmonary Deposits from a Sandpaper Worker: A Study by Electron Microscopy and X-Ray Microanalysis

1982 ◽  
Vol 40 ◽  
pp. 52-53
Author(s):  
S. K. Peng ◽  
M.A. Egy ◽  
J. K. Singh ◽  
M.B. Bishop
Keyword(s):  
Electron Microscopy ◽  
Environmental Pollution ◽  
Rare Case ◽  
Interstitial Fibrosis ◽  
X Ray ◽  
Documented Case ◽  
Etiologic Agents ◽  
Pulmonary Interstitial Fibrosis ◽  
Gold Miners ◽  
Pulmonary Changes

Electron microscopy and energy dispersive x-ray microanalysis (EDXA) are found to be very useful tools for identification of etiologic agents in pneumoconiosis or interstitial pulmonary disorders. Pulmonary interstitial fibrosis and granulomatosis are frequently associated with occupational and environmental pollution. Numerous reports of pneumoconiosis in various occupations such as coal and gold miners are presented in the literature. However, there is no known documented case of pulmonary changes in workers in the sandpaper industry. This study reports a rare case of pulmonary granulomatosis containing deposits from abrasives of sandpaper diagnosed by using EDXA.

Clinical aspects of reactive oxygen and nitrogen species

2004 ◽  
Vol 71 ◽  
pp. 121-133 ◽  
Author(s):  
Ascan Warnholtz ◽  
Maria Wendt ◽  
Michael August ◽  
Thomas Münzel
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Risk Factor ◽  
Endothelial Dysfunction ◽  
Vascular Tissue ◽  
Rapid Development ◽  
Reactive Oxygen ◽  
Clinical Aspects ◽  
No Production ◽  
Oxygen Species

Endothelial dysfunction in the setting of cardiovascular risk factors, such as hypercholesterolaemia, hypertension, diabetes mellitus and chronic smoking, as well as in the setting of heart failure, has been shown to be at least partly dependent on the production of reactive oxygen species in endothelial and/or smooth muscle cells and the adventitia, and the subsequent decrease in vascular bioavailability of NO. Superoxide-producing enzymes involved in increased oxidative stress within vascular tissue include NAD(P)H-oxidase, xanthine oxidase and endothelial nitric oxide synthase in an uncoupled state. Recent studies indicate that endothelial dysfunction of peripheral and coronary resistance and conductance vessels represents a strong and independent risk factor for future cardiovascular events. Ways to reduce endothelial dysfunction include risk-factor modification and treatment with substances that have been shown to reduce oxidative stress and, simultaneously, to stimulate endothelial NO production, such as inhibitors of angiotensin-converting enzyme or the statins. In contrast, in conditions where increased production of reactive oxygen species, such as superoxide, in vascular tissue is established, treatment with NO, e.g. via administration of nitroglycerin, results in a rapid development of endothelial dysfunction, which may worsen the prognosis in patients with established coronary artery disease.

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