scholarly journals Significance of platelet counts in health and disease: Insights from a population study using data from the National Health and Nutrition Examination Survey

2019 ◽  
Vol 7 (30) ◽  
pp. 4-11
Author(s):  
Sariya Wongsaengsak ◽  
Jeff Dennis ◽  
Meily Arevalo ◽  
Somedeb Ball ◽  
Kenneth Nugent
Keyword(s):  
Population Study ◽  
National Health ◽  
Mexican Americans ◽  
Large Population ◽  
Chronic Obstructive ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Health And Disease ◽  
Using Data

Background: Platelets are important mediators of coagulation, inflammation, andatherosclerosis. We conducted a large population study with National Health and NutritionExamination Survey (NHANES) data to understand the relationship of total platelet count(TPC) with health and disease in humans.Methods: NHANES is a cross-sectional survey of non-institutionalized United States adults,administered every 2 years by the Centers for Disease Control and Prevention. Participantsanswer a questionnaire, receive a physical examination, and undergo laboratory tests. TPCvalues were analyzed for a six-year period of NHANES (2011–2016). Weighted 10th and 90thpercentiles were calculated, and logistic regression was used to predict likelihood (Odds ratio[OR]) of being in categories with TPC < 10th percentile or > 90th percentile. Statistical analysiswas performed using Stata/SE 15.1, using population weights for complex survey design.Results: The mean TPC for our sample (N = 17,969) was 236 × 103/μL (SD = 59 × 103)with the 10th percentile 170 × 103/μL and the 90th percentile 311 × 103/μL. Hispanics (otherthan Mexican Americans) and obese individuals had lower odds of a TPC < 10th percentile.Males, Blacks, adults aged ≥ 45 years, and those with a recent (last 12 months) hospital staywere more likely to have a TPC < 10th percentile. Obese individuals and Mexican Americanshad higher odds of having TPC > 90th percentile. Individuals with a congestive heart failure(CHF) or coronary heart disease (CHD) diagnosis had over twice the odds (OR 2.06, 95% CI:1.50-2.82, p =< 0.001, and 2.11, 95% CI: 1.48-3.01, p =< 0.001, respectively) of having TPC<10th percentile. Individuals with an emphysema or asthma diagnosis were more likely to haveTPC > 90th percentile (OR 1.84, 95% CI: 1.08-3.13, p = 0.026, and 1.25, 95% CI: 1.00-1.56,p = 0.046, respectively). A diagnosis of chronic obstructive pulmonary disease and cancer didnot have significant associations with TPC.Conclusions: Our study showed that obese individuals are more likely to havehigher TPC. Individuals with CHF and CHD had higher odds of having TPC < 10thpercentile, and those with emphysema and asthma were more likely to have TPC > 90thpercentile.

scholarly journals Relationship between Smoking Activity and Chronic Obstructive Pulmonary Disease in the Zainoel Abidin General Hospital, Banda Aceh, Indonesia

2020 ◽  
Vol 8 (B) ◽  
pp. 705-707
Author(s):  
Liza Salawati ◽  
Husnah Husnah ◽  
Yusuf Nawawi ◽  
Zainal A. Muchlisin
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
General Hospital ◽  
Pulmonary Disease ◽  
Stage Iii ◽  
Chronic Obstructive ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Banda Aceh ◽  
Heavy Smokers

BACKGROUND: Exposure to cigarette smoke is one risk factor that can lead to the development of chronic obstructive pulmonary disease (COPD). AIM: The aim of this study was to examine the relationship between smoking and the stage of COPD. METHODS: This study used a cross-sectional survey design. A total of 60 COPD patients were involved in the study between September and November 2015 at the pulmonary ward of Zainoel Abidin General Hospital (ZAGH), Banda Aceh, Indonesia. The data were analyzed with the non-parametric bivariate test. RESULTS: The results showed that 55% of patients with COPD were aged between 40 and 60 years; 63.33% of them were heavy smokers. About 50% of moderate smokers suffered from Stage III COPD, while 34.21% of heavy smokers suffered from Stage III and Stage VI (severe) COPD, respectively, with p = 0.007. CONCLUSIONS: There is a strong relationship between smoking and COPD stage among patients at ZAGH.

Abstract 1090: Goal Attainment for LDL-C, HDL-C, Triglycerides, and All Lipids in U.S. Adults: National Health and Nutrition Examination Survey 2003–2004

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Heli Ghandehari ◽  
Sachin Kamal-Bahl ◽  
Nathan D Wong
Keyword(s):  
Risk Factors ◽  
National Health ◽  
Mexican Americans ◽  
Goal Attainment ◽  
Population Data ◽  
Nutrition Examination Survey ◽  
Lipid Levels ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Health And Nutrition

Background: Recent U.S. population data are lacking regarding the achievement of recommended lipid levels according to demographic factors and comorbidities. We evaluated the extent of LDL-C, HDL-C, triglyceride, and overall lipid goal attainment in U.S. adults. Design, Setting, and Participants: Data analysis from adults aged ≥20 who had fasted for ≥8 hours (n=2987 representing 132.7 million) in the National Health and Nutrition Examination Survey 2003–2004, a representative cross-sectional survey of the non-institutionalized civilian U.S. population. Main Outcome Measures: The proportion of adults at recommended levels for LDL-C, HDL-C, triglycerides, and all lipids were examined by gender, age, ethnicity and the presence of cardiovascular disease (CVD), diabetes (DM) or metabolic syndrome (MetS). Goals were <100 mg/dl for LDL-C for DM, CVD, or 2+ risk factors and >20% 10-year risk for coronary heart disease (CHD), <130 mg/dl if 2+ risk factors and ≤20% 10-year risk for CHD, or <160 mg/dl if <2 risk factors; ≥40 mg/dl (male) or ≥50 mg/dl (female) for HDL-C; and <150 mg/dl for triglycerides. Results: The proportion at goal for LDL-C was 74.5%, HDL-C 73.2%, triglycerides 73.6%, and 47.5% for all lipids. Control of LDL-C and triglycerides was greater in females, and HDL-C greater in males. Mexican-Americans and persons with CVD, DM, or MetS were least likely to be at recommended levels (see Table ). Table . Proportion (%) of US adults 2003–2004 at recommended levels for LDL-C, HDL-C, triglycerides, and all lipids Conclusions: While three-fourths of U.S. adults are at recommended levels for LDL-C, HDL-C and triglycerides individually, less than half are at goal for all lipids. For persons with DM or CVD, only a third are at goal for LDL-C and only a sixth are at goal for all lipids. Improved treatment efforts to optimize goal attainment of all lipids are required.

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