scholarly journals Effect of vitamin C on pregnancy rate and 8-OHdG levels during heat stress in post-partum dairy cattle

2021 ◽  
Vol 36 (4) ◽  
pp. 194-202
Author(s):  
Armağan Kirdeci ◽  
Hayrettin Çetin ◽  
Sanan Raza
2016 ◽  
Vol 50 (1) ◽  
Author(s):  
Atilla Yildiz ◽  
Zeki Erisir

The objective of this study was to evaluate effects of a daily oral drench of Propylene Glycol (PG) on fertility in dairy cows experiencing seasonal heat stress. In treatment group, cows (n=9) were treated with drenching 250 ml propylene glycol once daily from 3 to 15 days post-partum following the morning milking. Another group of cows (n=9) was selected as untreated control. The serum beta-hydroxybutyrate (BHBA) concentrations were used as indicators of energy status of the cows. Days to onset of luteal activity, calving to first service interval and pregnancy rate to first service were used to evaluate the reproductive performance. There was no difference in onset of luteal activity postpartum between the treatment and control groups. But the cows in the treatment group tended to have shorter intervals from calving to first insemination compared with cows in control group. The pregnancy rate to first service for cows treated with PG was 2.50 times greater compared with cows in control group. The energy balance was less negative for treatment group compared with control cows. In conclusion, although, drenching with 250 mL of PG per day from 3 to 15 days after calving did not improve the onset of luteal activity postpartum, treated cows tended to have shorter intervals from calving until first service. Propylene glycol administration would improve the negative energy balance status as observed by serum BHBA concentration, which might be an advantage to increase pregnancy rate at first AI in dairy cows experiencing seasonal heat stress.


BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Rui Shi ◽  
Luiz Fernando Brito ◽  
Aoxing Liu ◽  
Hanpeng Luo ◽  
Ziwei Chen ◽  
...  

Abstract Background The effect of heat stress on livestock production is a worldwide issue. Animal performance is influenced by exposure to harsh environmental conditions potentially causing genotype-by-environment interactions (G × E), especially in highproducing animals. In this context, the main objectives of this study were to (1) detect the time periods in which heifer fertility traits are more sensitive to the exposure to high environmental temperature and/or humidity, (2) investigate G × E due to heat stress in heifer fertility traits, and, (3) identify genomic regions associated with heifer fertility and heat tolerance in Holstein cattle. Results Phenotypic records for three heifer fertility traits (i.e., age at first calving, interval from first to last service, and conception rate at the first service) were collected, from 2005 to 2018, for 56,998 Holstein heifers raised in 15 herds in the Beijing area (China). By integrating environmental data, including hourly air temperature and relative humidity, the critical periods in which the heifers are more sensitive to heat stress were located in more than 30 days before the first service for age at first calving and interval from first to last service, or 10 days before and less than 60 days after the first service for conception rate. Using reaction norm models, significant G × E was detected for all three traits regarding both environmental gradients, proportion of days exceeding heat threshold, and minimum temperature-humidity index. Through single-step genome-wide association studies, PLAG1, AMHR2, SP1, KRT8, KRT18, MLH1, and EOMES were suggested as candidate genes for heifer fertility. The genes HCRTR1, AGRP, PC, and GUCY1B1 are strong candidates for association with heat tolerance. Conclusions The critical periods in which the reproductive performance of heifers is more sensitive to heat stress are trait-dependent. Thus, detailed analysis should be conducted to determine this particular period for other fertility traits. The considerable magnitude of G × E and sire re-ranking indicates the necessity to consider G × E in dairy cattle breeding schemes. This will enable selection of more heat-tolerant animals with high reproductive efficiency under harsh climatic conditions. Lastly, the candidate genes identified to be linked with response to heat stress provide a better understanding of the underlying biological mechanisms of heat tolerance in dairy cattle.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 168-168
Author(s):  
Melissa S Roths ◽  
Megan A Abeyta ◽  
Tori Rudolph ◽  
Brittany Wilson ◽  
Matthew B Hudson ◽  
...  

Abstract Heat stress (HS) occurs when internal body temperatures are elevated above a thermoneutral zone in response to extreme environmental temperatures. In the U.S. dairy industry, HS results in economic loss due to decreased feed intake, milk quality, and milk yield. Previous work has demonstrated increased plasma urea nitrogen in heat stressed dairy cattle which is thought to originate from increased skeletal muscle proteolysis, however this has not been empirically established. The objective of this investigation was to determine the extent to which HS promotes proteolysis in skeletal muscle of dairy cattle. We hypothesized HS would increase activation of the calpain and proteasome systems in skeletal muscle. To test this hypothesis, following a 3-d acclimation period in individual box stalls, all lactating dairy cows were held under thermoneutral (TN) conditions for 4-d for collection of baseline measures and then exposed to TN or HS conditions for 7-d followed by a biopsy of semitendinosus (n=8/group). To induce HS, cattle were fitted with electric heating blankets, which they wore for the duration of the heating period. This approach increased rectal temperature 1.1°C (P< 0.05), respiratory rate by 33 bpm (P< 0.05), plasma urea nitrogen by 19% (P=0.08) and milk urea nitrogen by 26% (P< 0.05), and decreased dry matter intake by 32% (P< 0.05) and milk production by 26% (P< 0.05) confirming HS. Contrary to our expectations, we discovered that calpain I and II abundance and activation, and calpain activity were similar between groups. Likewise, protein expression of E3 ligases, MafBx and Murf1, were similar between groups as was total ubiquitinated proteins and proteasome activity. Collectively, and counter to our hypothesis, these results suggest skeletal muscle proteolysis is not increased following 7-d of HS. These data question the presumed dogma that increased blood urea nitrogen is due to elevated proteolysis in skeletal muscle.


2009 ◽  
Vol 72 (5) ◽  
pp. 741-746 ◽  
Author(s):  
J. Kauffold ◽  
R. Gommel ◽  
K. Failing ◽  
N. Beynon ◽  
A. Wehrend
Keyword(s):  

2010 ◽  
Vol 55 (No. 5) ◽  
pp. 209-220 ◽  
Author(s):  
H. Imik ◽  
M. Aydemir Atasever ◽  
M. Koc ◽  
M. Atasever ◽  
K. Ozturan

This research investigates the effects of adding vitamin E, vitamin C, vitamin E+C, and alpha lipoic acid to feed rations for Japanese quails (Coturnix coturnix japonica) exposed to heat stress. The aspects studied were growth performance, carcass composition and breast meat characteristics. Five groups of quails, containing 50 birds each (250 Japanese quails: 150 female and 100 male) were used. The 21-days-old birds were fed for a period of 21 days, and they were kept in a controlled environment with a temperature of 34˚C between 08:00 and 17:00 and a temperature of 24˚C for the remaining part of the day. The five groups under study included: a control group without any additive (BS), a group fed diets with vitamin E (BSE), with vitamin C (BSC), with vitamin E+C (BSEC) and with lipoic acid (BSLA). The supplement additions to the diets did not affect the growth performance and carcass composition of the birds. The TBA (malonaldehyde) value of the BS group was significantly higher (P < 0.001) than in the other groups. L*, a*, and b* values in muscle samples, superficialis pectoralis muscle (SPM) and deep pectoralis muscle (DPM), were determined. In the samples from the SPM, the L* value of the BS group was higher than in the BSC group; the a* value of the BSE group was higher than in the BS group; and the b* value of the BSC group was higher than in the BS group (P < 0.05). In the samples from the DPM, the L* value of the BS group was higher than in the BSEC group (P < 0.05); the a* values of the BSE and BSEC groups were higher than in the BS group (P < 0.05); and the b* values of the BSC, BSEC and BSLA groups were higher than in the BS group (P < 0.01). In the microbiological analysis of meat, total aerobic mesophilic bacterial counts of the BS and BSE groups were higher than the counts in the BSC, BSEC, and BSLA groups (P < 0.01); coliform bacterial counts were higher in the BSE group than in the BSC group (P < 0.05); and lactic acid was higher in the BSE and BSEC groups than in the BSC and BSLA groups (P < 0.01). In conclusion, the supplemented antioxidants did not exhibit any significant effect on growth performance, but they significantly decreased lipid oxidation in the meat.  


2021 ◽  
Vol 226 ◽  
pp. 00025
Author(s):  
Imam Suswoyo ◽  
Ismoyowati Ismoyowati ◽  
Wahyu Widodo ◽  
Zane Vincēviča–Gaile

Global warming affected increasing the risk of ducks to be more succeptable to heat stress which leads to decrease welfare and production. This research aimed to study duck welfare and productivity under probiotic and antioxidants administration at commercial farms. The method used was experiment with Completely Randomized Designed (CRD) based on factorial pattern. The treatment was dose of natural/homemade and commercial probiotics combined with vitamin C at 400 mg kg–1 and 600 mg kg–1 feed. Thus there were four treatment combinations. Each treatment was replicated five times, totally were 20 flocks of duck. Each flock had 50 laying females so there were 1 000 ducks. The treatment was conduced for 2 mo. The parameters observed included, i) duck welfare based on Heterophyl/Lymphocyte (H/L) ratio; ii) egg production consisted of (a) duck day production, and (b) egg weight. This study concluded that administration of combination between homemade probiotic and vitamin C at 600 mg kg–1 feed significantly (p < 0.05) increased duck welfare and egg production but did not affect egg weight.


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