scholarly journals Clinical Progress Note: Point-of-Care Ultrasound Applications in COVID-19

2020 ◽  
Vol 15 (6) ◽  
pp. 353-355 ◽  
Author(s):  
Benji K Mathews ◽  
Seth Koenig ◽  
Linda Kurian ◽  
Benjamin Galen ◽  
Gregory Mints ◽  
...  
Keyword(s):  
Septic Shock ◽  
Respiratory Failure ◽  
Critical Illness ◽  
Literature Search ◽  
Point Of Care ◽  
Severe Illness ◽  
Point Of Care Ultrasound ◽  
The Novel ◽  
Novel Coronavirus ◽  
Ultrasound Applications

COVID-19, the disease caused by the novel coronavirus SARS-CoV-2, was declared a pandemic on March 11, 2020. Although most patients (81%) develop mild illness, 14% develop severe illness, and 5% develop critical illness, including acute respiratory failure, septic shock, and multiorgan dysfunction.1 Point-of-care ultrasound (POCUS), or bedside ultrasound performed by a clinician caring for the patient, is being used to support the diagnosis and serially monitor patients with COVID-19. We performed a literature search of electronically discoverable peer-reviewed publications on POCUS use in COVID-19 from December 1, 2019, to April 10, 2020. We review key POCUS applications that are most relevant to frontline providers in the care of COVID-19 patients.

scholarly journals Just the Facts: Recommendations on point-of-care ultrasound use and machine infection control during the coronavirus disease 2019 pandemic

CJEM ◽  
2020 ◽  
Vol 22 (4) ◽  
pp. 445-449 ◽  
Author(s):  
Daniel J. Kim ◽  
Tomislav Jelic ◽  
Michael Y. Woo ◽  
Claire Heslop ◽  
Paul Olszynski
Keyword(s):  
Infection Control ◽  
Point Of Care ◽  
Control Measures ◽  
World Health ◽  
Point Of Care Ultrasound ◽  
The Novel ◽  
Infection Control Measures ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Widespread Interest

The World Health Organization declared the novel coronavirus disease 2019 (COVID-19) to be a pandemic on March 11, 2020, and, currently, there are over 10,000 confirmed cases in Canada, with this number expected to grow exponentially. There has been widespread interest in the use of point-of-care ultrasound (POCUS) in the management of patients with suspected COVID-19. The CAEP Emergency Ultrasound Committee has developed recommendations on the use of POCUS in these patients, with an emphasis on machine infection control measures.

scholarly journals ASE Statement on Point-of-Care Ultrasound during the 2019 Novel Coronavirus Pandemic

2020 ◽  
Vol 33 (6) ◽  
pp. 670-673 ◽  
Author(s):  
Amer M. Johri ◽  
Benjamin Galen ◽  
James N. Kirkpatrick ◽  
Michael Lanspa ◽  
Sharon Mulvagh ◽  
...  
Keyword(s):  
Point Of Care ◽  
Point Of Care Ultrasound ◽  
Novel Coronavirus

scholarly journals Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2

Viruses ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 582 ◽  
Author(s):  
Nadin Younes ◽  
Duaa W. Al-Sadeq ◽  
Hadeel AL-Jighefee ◽  
Salma Younes ◽  
Ola Al-Jamal ◽  
...  
Keyword(s):  
Point Of Care ◽  
Accurate Determination ◽  
High Sensitivity ◽  
Laboratory Diagnosis ◽  
The Novel ◽  
Viral Shedding ◽  
Diagnostic Capacity ◽  
Commercial Kits ◽  
Novel Coronavirus ◽  
Diagnostic Technologies

The recent outbreak of the Coronavirus disease 2019 (COVID-19) has quickly spread worldwide since its discovery in Wuhan city, China in December 2019. A comprehensive strategy, including surveillance, diagnostics, research, clinical treatment, and development of vaccines, is urgently needed to win the battle against COVID-19. The past three unprecedented outbreaks of emerging human coronavirus infections at the beginning of the 21st century have highlighted the importance of readily available, accurate, and rapid diagnostic technologies to contain emerging and re-emerging pandemics. Real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) based assays performed on respiratory specimens remain the gold standard for COVID-19 diagnostics. However, point-of-care technologies and serologic immunoassays are rapidly emerging with high sensitivity and specificity as well. Even though excellent techniques are available for the diagnosis of symptomatic patients with COVID-19 in well-equipped laboratories; critical gaps still remain in screening asymptomatic people who are in the incubation phase of the virus, as well as in the accurate determination of live viral shedding during convalescence to inform decisions for ending isolation. This review article aims to discuss the currently available laboratory methods and surveillance technologies available for the detection of COVID-19, their performance characteristics and highlight the gaps in current diagnostic capacity, and finally, propose potential solutions. We also summarize the specifications of the majority of the available commercial kits (PCR, EIA, and POC) for laboratory diagnosis of COVID-19.

New Perspectives for Modern Trauma Management – Lessons Learned from 25 Years FAST and 15 Years E-FAST

2019 ◽  
Vol 40 (05) ◽  
pp. 560-583 ◽  
Author(s):  
Joseph Osterwalder ◽  
Gebhard Mathis ◽  
Beatrice Hoffmann
Keyword(s):  
Life Support ◽  
Point Of Care ◽  
Clinical Situation ◽  
Lessons Learned ◽  
Advanced Trauma Life Support ◽  
Point Of Care Ultrasound ◽  
Trauma Management ◽  
Abdominal Image ◽  
Trauma Surgeons ◽  
Ultrasound Applications

AbstractE-FAST (Extended-Focused Assessment with Sonography for Trauma) is now a widely utilized and internationally recognized standard exam in trauma care. It is highly accepted by emergency physicians and trauma surgeons alike. Thanks to the popularity of PoCUS (point-of-care ultrasound), it has continued to evolve over the last years and can now improve trauma diagnosis at all stages of the primary ABCDE. This review article summarizes key observations made over recent years and also highlights the extension of FAST into E-FAST in the context of PoCUS and CT developments for modern trauma management. Time has come to learn the lessons from 25 years of FAST and 15 years of E-FAST. We should redefine and position ultrasound in the primary ATLS survey (Advanced Trauma Life Support) on two levels: 1. Basic ATLS with new clinical questions, six additional abdominal image sections and one or more follow-up examinations depending on the clinical situation, and 2. Advanced ATLS with ultrasound applications for the entire trauma ABCDE.

scholarly journals Point-of-Care Diagnostic Services as an Integral Part of Health Services during the Novel Coronavirus 2019 Era

Diagnostics ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 449
Author(s):  
Tivani P. Mashamba-Thompson ◽  
Paul K. Drain
Keyword(s):  
Health Services ◽  
Mobile Technology ◽  
Point Of Care ◽  
Holistic Approach ◽  
The Novel ◽  
Pathology Laboratory ◽  
Laboratory Services ◽  
Point Of Care Diagnostics ◽  
Private And Public ◽  
Novel Coronavirus

Point-of-care (POC) diagnostic services are commonly associated with pathology laboratory services. This issue presents a holistic approach to POC diagnostics services from a variety of disciplines including pathology, radiological and information technology as well as mobile technology and artificial intelligence. This highlights the need for transdisciplinary collaboration to ensure the efficient development and implementation of point-of-care diagnostics. The advent of the novel coronavirus 2019 (COVID-19) pandemic has prompted rapid advances in the development of new POC diagnostics. Global private and public sector agencies have significantly increased their investment in the development of POC diagnostics. There is no longer a question about the availability and accessibility of POC diagnostics. The question is “how can POC diagnostic services be integrated into health services in way that is useful and acceptable in the COVID-19 era?”.

scholarly journals Unusual presentation of COVID-19 in a child complicated by massive acute pulmonary embolism and lung infarction

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Tahani Bin Ali ◽  
Ghaleb Elyamany ◽  
Maha Nojoom ◽  
Mohamed Alfaki ◽  
Hassan Alahmari ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Respiratory Failure ◽  
Anticoagulant Therapy ◽  
Acute Pulmonary Embolism ◽  
Respiratory Illness ◽  
Unusual Presentation ◽  
The Novel ◽  
Limited Data ◽  
Progressive Respiratory Failure ◽  
Novel Coronavirus

The Novel Coronavirus 2019 (SARSCoV- 2), which was first reported on in Wuhan, China, in late December 2019, causes a respiratory illness called COVID- 19 Disease. COVID-19 is most likely causing a hypercoagulable state, however the prevalence of acute venothromboembolism is still unknown. Limited data suggest pulmonary microvascular thrombosis may play a role in progressive respiratory failure. Here, we report a case of a child with an unusual presentation of COVID-19 presented initially by dry cough without fever and complicated by massive acute pulmonary embolism and lung infarction and treated successfully by hydroxychloroquine and azithromycin, in addition to anticoagulant therapy.

scholarly journals Point-of-Care Ultrasound in Respiratory Failure

CHEST Journal ◽  
2020 ◽  
Vol 157 (3) ◽  
pp. 740
Author(s):  
Nicholas Smallwood ◽  
Jennie Stephens ◽  
Martin Dachsel ◽  
Ashley Miller ◽  
Andrew Walden
Keyword(s):  
Respiratory Failure ◽  
Point Of Care ◽  
Point Of Care Ultrasound

scholarly journals The role of haematological parameters in patients with COVID-19 and influenza virus infection

2020 ◽  
Vol 148 ◽  
Author(s):  
Sumeyye Kazancioglu ◽  
Aliye Bastug ◽  
Bahadir Orkun Ozbay ◽  
Nizamettin Kemirtlek ◽  
Hurrem Bodur
Keyword(s):  
Laboratory Data ◽  
Influenza Virus Infection ◽  
Haematological Parameters ◽  
Severe Illness ◽  
Healthy Controls ◽  
The Novel ◽  
Lymphocyte Ratio ◽  
End Of Treatment ◽  
Novel Coronavirus

Abstract SARS-CoV-2, the causative agent of coronavirus disease 19 (COVID-19), was identified in Wuhan, China. Since then, the novel coronavirus started to be compared to influenza. The haematological parameters and inflammatory indexes are associated with severe illness in COVID-19 patients. In this study, the laboratory data of 120 COVID-19 patients, 100 influenza patients and 61 healthy controls were evaluated. Lower lymphocytes, eosinophils, basophils, platelets and higher delta neutrophil index (DNI), neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were found in COVID-19 and influenza groups compared to healthy controls. The eosinophils, lymphocytes and PLR made the highest contribution to differentiate COVID-19 patients from healthy controls (area under the curves (AUCs): 0.819, 0.817 and 0.716, respectively; P-value is <0.0001 for all). The NLR, the optimal cut-off value was 3.58, which resulted in a sensitivity of 30.8 and a specificity of 100 (AUC: 0.677, P < 0.0001). Higher leucocytes, neutrophils, DNI, NLR, PLR and lower lymphocytes, red blood cells, haemoglobin, haematocrit levels were found in severe patients at the end of treatment. Nonsevere patients showed an upward trend for lymphocytes, eosinophils and platelets, and a downward trend for neutrophils, DNI, NLR and PLR. However, there was an increasing trend for eosinophils, platelets and PLR in severe patients. In conclusion, NLR and PLR can be used as biomarkers to distinguish COVID-19 patients from healthy people and to predict the severity of COVID-19. The increasing value of PLR during follow-up may be more useful compared to NLR to predict the disease severity.

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