scholarly journals Unusual presentation of COVID-19 in a child complicated by massive acute pulmonary embolism and lung infarction

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Tahani Bin Ali ◽  
Ghaleb Elyamany ◽  
Maha Nojoom ◽  
Mohamed Alfaki ◽  
Hassan Alahmari ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Respiratory Failure ◽  
Anticoagulant Therapy ◽  
Acute Pulmonary Embolism ◽  
Respiratory Illness ◽  
Unusual Presentation ◽  
The Novel ◽  
Limited Data ◽  
Progressive Respiratory Failure ◽  
Novel Coronavirus

The Novel Coronavirus 2019 (SARSCoV- 2), which was first reported on in Wuhan, China, in late December 2019, causes a respiratory illness called COVID- 19 Disease. COVID-19 is most likely causing a hypercoagulable state, however the prevalence of acute venothromboembolism is still unknown. Limited data suggest pulmonary microvascular thrombosis may play a role in progressive respiratory failure. Here, we report a case of a child with an unusual presentation of COVID-19 presented initially by dry cough without fever and complicated by massive acute pulmonary embolism and lung infarction and treated successfully by hydroxychloroquine and azithromycin, in addition to anticoagulant therapy.

COMPARATIVE EVALUATION OF TREATMENT OF ACUTE PULMONARY EMBOLISM (ACCORDING TO DATA CLINICAL HOSPITAL OF ALMATY #7)

Vestnik ◽  
2021 ◽  
pp. 57-61
Author(s):  
С.М. Анартаев ◽  
О. Тайманулы ◽  
Д.М. Кайралиев ◽  
К.А. Ергешов ◽  
Е.Б. Ибадуллаев ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Anticoagulant Therapy ◽  
Comparative Evaluation ◽  
Acute Pulmonary Embolism ◽  
Therapy Group ◽  
Heparin Group ◽  
Group Iii ◽  
Group I ◽  
Complex Therapy ◽  
Acute Pe

В статье представлены результаты сравнительного анализа 50 больных тромбоэмболии легочной артерии (ТЭЛА), которые по способу лечения были разделены на 3 группы: I группа - с антикоагулянтной терапией (гепарин). II группа - с селективной катетерной тромболитической (альтеплаза) и антикоагулянтной терапией. III группа - с катетерной аспирационной тромбоэкстракцией; Установлено, что на фоне комплексной терапии, включающую тромболитическую и антикоагулянтную терапии наблюдалась лучшая выживаемость пациентов с острой ТЭЛА. The article presents results of a comparative analysis of 50 patients with pulmonary embolism (PE), which were divided into 3 groups according to the method of treatment: Group I - with anticoagulant therapy (heparin); Group II - with catheter thrombolytic (alteplase) and anticoagulant therapy. Group III - with catheter embolectomy (aspiration thromboextraction); It was found against the background of complex therapy, including thrombolytic and anticoagulant therapy, there was a better survival rate for patients with acute PE.

scholarly journals Covid-19 and food security: Jeopardy management and posterity deliberations

2021 ◽  
Vol 10 (2) ◽  
pp. 01-05
Author(s):  
Augustine Owusu-Addo ◽  
Atianashie Miracle A ◽  
Chukwuma Chinaza Adaobi ◽  
Larissa Agbemelo-Tsomafo
Keyword(s):  
Food Processing ◽  
Respiratory Illness ◽  
The United States ◽  
The Novel ◽  
Food Handling ◽  
Global Pandemic ◽  
Food Borne ◽  
Novel Coronavirus ◽  
Food Borne Infections ◽  
Safety Guidelines

COVID-19, also known as the ‘novel coronavirus disease 2019’, is a respiratory illness and the causative pathogen is officially named as ‘SARS-CoV-2’. Infections with SARS-CoV-2 have now been amplified to a global pandemic – as of April 3, 2020, nearly 1,018,000 cases have been confirmed in more than 195 countries, including more than 300,000 cases within the United States. Public safety guidelines are followed worldwide to stop the spread of COVID-19 and stay healthy. Despite COVID-19 is a respiratory illness with mode of invasion through the respiratory tract, not the gastrointestinal tract, an average food consumer is anxious and concerned about the food safety. Could an individual catch the deadly contagious COVID-19 from groceries brought home from the supermarket – or from the next restaurant takeout order? This brief review elucidates the epidemiology and pathobiological mechanism(s) of SARS-CoV-2 and its implications in food-borne infections, transmission via food surfaces, food processing and food handling.

Thirty-day outcomes in patients with acute pulmonary embolism who discontinued anticoagulant therapy before 90 days

2018 ◽  
Vol 206 ◽  
pp. 1-10 ◽  
Author(s):  
José A. Nieto ◽  
Julio A. Vicente ◽  
Luis M. Prieto ◽  
David Jiménez ◽  
Behnood Bikdeli ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Anticoagulant Therapy ◽  
Acute Pulmonary Embolism

scholarly journals 'STEMI-like' acute pulmonary embolism, an unusual presentation

2014 ◽  
Vol 2014 (nov20 1) ◽  
pp. bcr2014206517-bcr2014206517 ◽  
Author(s):  
A. Abdalla ◽  
F. Kelly
Keyword(s):  
Pulmonary Embolism ◽  
Acute Pulmonary Embolism ◽  
Unusual Presentation

scholarly journals Clinical Progress Note: Point-of-Care Ultrasound Applications in COVID-19

2020 ◽  
Vol 15 (6) ◽  
pp. 353-355 ◽  
Author(s):  
Benji K Mathews ◽  
Seth Koenig ◽  
Linda Kurian ◽  
Benjamin Galen ◽  
Gregory Mints ◽  
...  
Keyword(s):  
Septic Shock ◽  
Respiratory Failure ◽  
Critical Illness ◽  
Literature Search ◽  
Point Of Care ◽  
Severe Illness ◽  
Point Of Care Ultrasound ◽  
The Novel ◽  
Novel Coronavirus ◽  
Ultrasound Applications

COVID-19, the disease caused by the novel coronavirus SARS-CoV-2, was declared a pandemic on March 11, 2020. Although most patients (81%) develop mild illness, 14% develop severe illness, and 5% develop critical illness, including acute respiratory failure, septic shock, and multiorgan dysfunction.1 Point-of-care ultrasound (POCUS), or bedside ultrasound performed by a clinician caring for the patient, is being used to support the diagnosis and serially monitor patients with COVID-19. We performed a literature search of electronically discoverable peer-reviewed publications on POCUS use in COVID-19 from December 1, 2019, to April 10, 2020. We review key POCUS applications that are most relevant to frontline providers in the care of COVID-19 patients.

scholarly journals Controlling the cascade of corona

2020 ◽  
Vol 5 (3) ◽  
Author(s):  
Muneeba Azmat
Keyword(s):  
Public Health ◽  
The Novel ◽  
Limited Data ◽  
Press Releases ◽  
The Public ◽  
Health Measures ◽  
First Case ◽  
Pandemic Response ◽  
Potential Impact ◽  
Novel Coronavirus

The pandemic of the 2019 novel Coronavirus has seen unprecedented exponential growth. Within three months, 192 countries have been affected, crossing more than 1 million confirmed cases and over 60 thousand deaths until the first week of April. Decision making in such a pandemic becomes difficult due to limited data on the nature of the disease and its propagation, course, prevention, and treatment. The pandemic response has varied from country to country and has resulted in a heterogeneous timeline for novel Coronavirus propagation. We compared the public health measures taken by various countries and the potential impact on the spread. We studied 6 countries including China, Italy, South Korea, Singapore, United Kingdom(UK), United States(US), and the special administrative region of Hong Kong. All articles, press releases, and websites of government entities published over a five-month period were included. A comparison of the date of the first diagnosed case, the spread of disease, and time since the first case and major public health policy implemented for prevention and containment and current cases was done. An emphasis on early and aggressive border restriction and surveillance of travelers from infected areas, use of information technology, and social distancing is necessary for control of the novel pandemic. Moving forwards, improvement in infrastructure, and adequate preparedness for pandemics is required.

scholarly journals Fluid and Electrolyte Disturbances in COVID-19 and Their Complications

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Mohammad Pourfridoni ◽  
Seyede Mahsa Abbasnia ◽  
Fateme Shafaei ◽  
Javad Razaviyan ◽  
Reza Heidari-Soureshjani
Keyword(s):  
Kidney Injury ◽  
Respiratory Illness ◽  
The Novel ◽  
Acute Respiratory Illness ◽  
Gi Tract ◽  
Angiotensin Converting Enzyme 2 ◽  
Intensive Care Patients ◽  
Electrolyte Disturbances ◽  
Novel Coronavirus ◽  
Tract Damage

The novel coronavirus disease 2019 (COVID-19) is the cause of an acute respiratory illness which has spread around the world. The virus infects the host by binding to the angiotensin-converting enzyme 2 (ACE2) receptors. Due to the presence of ACE2 receptors in the kidneys and gastrointestinal (GI) tract, kidneys and GI tract damage arising from the virus can be seen in patients and can cause acute conditions such as acute kidney injury (AKI) and digestive problems for the patient. One of the complications of kidneys and GI involvement in COVID-19 is fluid and electrolyte disturbances. The most common ones of these disorders are hyponatremia, hypernatremia, hypokalemia, hypocalcemia, hypochloremia, hypervolemia, and hypovolemia, which if left untreated, cause many problems for patients and even increase mortality. Fluid and electrolyte disturbances are more common in hospitalized and intensive care patients. Children are also at greater risk for fluid and electrolyte disturbances complications. Therefore, clinicians should pay special attention to the fluid and electrolyte status of patients. Changes in fluid and electrolyte levels can be a good indicator of disease progression.

scholarly journals Venous Doppler Ultrasound in Critically Ill Covid-19 Patients: Game Changer in Anticoagulation Therapy

2020 ◽  
Author(s):  
Marta Alfageme ◽  
Jorge González Plaza ◽  
María Luisa Collado ◽  
Santiago Méndez ◽  
Juan A. Gómez Patiño ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Respiratory Failure ◽  
Critically Ill ◽  
Doppler Ultrasound ◽  
Acute Pulmonary Embolism ◽  
Anticoagulation Therapy ◽  
Lower Limbs ◽  
Severe Respiratory Failure ◽  
Asymptomatic Patients ◽  
D Dimer

Abstract BackgroundCOVID-19 infection has been associated with a high rate of thrombotic events, such as deep vein thrombosis (DVT) and acute pulmonary embolism (APE).MethodsThe purpose of our retrospective study was to evaluate the prevalence of asymptomatic DVT in lower limbs in critically ill COVID-19 patients (n=23) with severe respiratory failure and high levels of D-dimer by bedside Doppler ultrasound (DU).ResultsDVT was diagnosed in 14 cases (60.87%), 5 in proximal venous territory and 9 in infrapopliteal veins. CTPA was performed in 6 patients and all of them showed acute pulmonary embolism (APE) at segmental or subsegmental branches of pulmonary arteries. These patients (APE or DVT confirmed) were treated with therapeutic doses of anticoagulant therapy.ConclusionIn critically COVID 19 ill ICU patients with severe respiratory failure y elevated D-dimer the incidence of asymptomatic DVT is high. We propose that DU allows detection of DVT in asymptomatic patients, adding a factor that may balance the decision to fully anticoagulated these patients.

scholarly journals Massive Pulmonary Embolism Complicating Coronavirus Disease 2019 (COVID-19) Pneumonia: A Case Report

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Shruti Hegde ◽  
Gemini Yesodharan ◽  
John Tedrow ◽  
Alena Goldman
Keyword(s):  
Pulmonary Embolism ◽  
Respiratory Failure ◽  
Acute Pulmonary Embolism ◽  
Ventilatory Support ◽  
Systolic Pressure ◽  
Hemodynamic Instability ◽  
Right Heart ◽  
Timely Diagnosis ◽  
Systemic Thrombolytic Therapy ◽  
Clinical Instability

Background. Patients with severe COVID-19 pneumonia are hypercoagulable and are at risk for acute pulmonary embolism. Timely diagnosis is imperative for their prognosis and recovery. This case describes an otherwise healthy 55-year-old man with respiratory failure requiring mechanical ventilatory support secondary to COVID-19 pneumonia. Massive acute pulmonary embolism with right heart failure complicated his course. Case. A healthy 55-year-old man presented to our emergency department (ED) with a sore throat, cough, and myalgia. A nasopharyngeal swab was obtained, and he was discharged for home quarantine. His swab turned positive for SARS-CoV-2 infection on real-time reverse transcriptase-polymerase chain reaction assay (RT-PCR) on day 2 of his ED visit. A week later, he represented with worsening shortness of breath, requiring intubation for hypoxic respiratory failure due to COVID-19 pneumonia. Initially, he was easy to oxygenate, had no hemodynamic compromise, and was afebrile. On day 3, he became febrile and developed significant hemodynamic instability requiring maximum vasopressor support and oxygenation difficulty. His ECG revealed sinus tachycardia with S1Q3T3 pattern. On bedside TTE, there was evidence of right heart strain and elevated pulmonary artery systolic pressure of 45 mmHg. All data was indicative of a massive APE as the etiology for his hemodynamic collapse. A decision was made to forgo computed tomography pulmonary angiography (CTPA), given his clinical instability, and systemic thrombolytic therapy was administered. Within the next 12-24 hours, his hemodynamic status significantly improved. Conclusions. This case highlights the importance of considering massive APE in COVID-19 patients as a cause of the sudden and rapid hemodynamic decline. Furthermore, timely diagnosis can be made to aid in appropriate management with the help of bedside TTE and ECG in cases where CTPA is not feasible secondary to the patient’s hemodynamic instability.

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