The Relationship Between Serum Vitamin B12 Level, Obesity, and Age : A Cross - Sectional Study

2020 ◽  
Vol 27 (2) ◽  
pp. 36-44
Author(s):  
Bani salameh , Ahmad A. ◽  
Al Dalala'h , Kafa M. ◽  
Bdour , Karam M. ◽  
Bani Hamad , Yazan S. ◽  
Alzu’bi , Ali A. ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

scholarly journals Association between Food Behaviour of Pregnant Women and Status of Serum Vitamin B12 and Neonatal Outcome – A Cross-Sectional Study

2019 ◽  
Vol 7 (1-2) ◽  
pp. 84-91
Author(s):  
Rowshan Afrooz ◽  
Lipika Ghosh ◽  
Abul Kalam Md Faruq ◽  
Mitheel Ibna Islam
Keyword(s):  
Birth Weight ◽  
Vitamin B12 ◽  
Pregnant Women ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Normal Serum ◽  
Urban Resident ◽  
Sectional Study ◽  
Cross Sectional ◽  
Low Serum

Background & objective: To find the association between serum vitamin B12 and food behavior of the pregnant women and its influence on perinatal outcome. Methods: This cross-sectional study was conducted in the Department of Obstetrics & Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka between June 2012 to July 2013. A total of 102 uncomplicated pregnant women attending at the Obstetrics & Gynaecology Department of BSMMU, Dhaka were the study population. Plasma vitamin B12 was measured by Abbott Axsym System using a Enzyme Immuno Assay Technique with the blood collected in a plain test tube. A serum vitamin B12 level of < 200 pg/mL was considered as low serum vitamin B12 level. The outcome variables were birth weight, small-for-date, neural tube defects and other congenital malformations. Result: The selected pregnant women were housewife (74.5%) from low socioeconomic strata. They were generally urban resident (90.2%) with mean age being 26.4 years. In terms of education 17.6% were primary level, 30.4% SSC level, 31.4% HSC level and 20.6% graduate and higher level educated. Majority (90.2%) was urban resident with average monthly family income being Taka 29460. One-third (33.3%) was overweight and 6.9% obese. Two-thirds (66.7%) were at 37-39 weeks of gestation and nullipara. More than 60% received ANC (antenatal care) aregularly. Over one-third (35.3%) had low serum vitamin B12 (< 200 pg/mL). The food behaviour of the women was found to be associated with vitamin B12 deficiency. The pregnant women with low serum vitamin B12 (< 200 pg/ml) had significantly lower weekly consumption of fishes and eggs which are the rich source of vitamin B12. The weekly fish, eggs and amount of milk consumed by the pregnant women with low serum vitamin B12 were much lower than those consumed by the pregnant women with normal serum vitamin B12. The pregnant women with low serum vitamin B12 were more likely to carry a higher risk of adverse perinatal outcome. The incidences of low-birth weight and small-for-dates were staggeringly higher in women with low serum vitamin B12 (33.3% and 27.8% respectively) compared to those in women with normal serum vitamin B12. Conclusion: The study concluded that pregnant women with low serum vitamin B12 are accustomed to taking low fish and eggs in their daily diet compared to those who have normal serum vitamin B12. The incidence of low birth weight and small-for-date babies are more prevalent in the pregnant women with subclinical deficiency of vitamin B12. Ibrahim Card Med J 2017; 7 (1&2): 84-91

scholarly journals Reduced levels of serum vitamin B12 in symptomatic cases of oral lichen planus: A cross-sectional study

2020 ◽  
Vol 10 (4) ◽  
pp. 578-582
Author(s):  
Shantala R. Naik ◽  
Prashant Gupta ◽  
Tanya Khaitan ◽  
Anjani Kumar Shukla
Keyword(s):  
Vitamin B12 ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Oral Lichen

scholarly journals Serum Vitamin D and B12 Levels in Alcoholic Male Patients: A Cross-sectional Study

2021 ◽  
Vol 9 (01) ◽  
pp. 47-51
Author(s):  
Archana Jayan ◽  
Buddhi Raj Pokhrel ◽  
Narayan Gautam ◽  
Amit Chandra Jha ◽  
Binaya Tamang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Liver Function ◽  
Alcohol Dependence ◽  
Vitamin B12 ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels

INTRODUCTION Alcohol dependence is a global problem and is rapidly increasing in developing countries. We aimed to analyze the serum levels of vitamin B12 and vitamin D in chronic alcoholic patients and their association with parameters of liver function. MATERIAL AND METHODS A cross-sectional study was carried out in Universal College of Medical Sciences, Bhairahawa, Nepal from March 2020 to September 2020 on patients visiting the Psychiatric Out Patient Department (OPD) for the treatment of alcohol dependence. The patients were categorized as excessive and moderate drinkers. Serum vitamin B12, vitamin D, and hepatic function parameters were measured. RESULTS The median serum vitamin B12 and vitamin D levels were 467.8 pg/ml and 24.9 ng/ml respectively. Excessive drinkers had significantly higher B12   levels than moderate drinkers. Vitamin B12   levels correlated positively with liver function parameters, as well as alcohol amount and duration of consumption. Vitamin D levels were insufficient in 57 (71.25%) of the overall participants. CONCLUSION Serum levels of vitamin B12 are not affected in patients with alcohol dependence. Alcohol consumption, however, reduces serum concentrations of vitamin D. Vitamin B12  concentration is positively associated with liver enzymes and other parameters of liver function.  

scholarly journals Vitamin B12 deficiency and diabetic neuropathy in patients taking metformin: a cross-sectional study

2019 ◽  
Vol 8 (10) ◽  
pp. 1324-1329 ◽  
Author(s):  
Mauricio Alvarez ◽  
Oswaldo Rincón Sierra ◽  
Ginna Saavedra ◽  
Sergio Moreno
Keyword(s):  
Diabetic Neuropathy ◽  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Inverse Correlation ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
B12 Deficiency ◽  
The Relationship ◽  
Higher Doses

Objective Vitamin B12 deficiency resulting from metformin use has been demonstrated in multiple studies. In this study, we aimed to evaluate the prevalence of vitamin B12 deficiency in patients with chronic metformin use and the relationship between vitamin B12 deficiency and diabetic neuropathy. Methods A cross-sectional study was conducted with 162 patients. Vitamin B12 levels were measured by chemiluminescence immunoassay. Diabetic neuropathy was evaluated by patient record, nerve conduction and Michigan test for the diagnosis of diabetic neuropathy. Additional data, including demographic characteristics were collected. A linear regression model was used to evaluate variables that correlated with vitamin B12 levels and diabetic neuropathy. Results Low vitamin B12 levels were found in 7.3% (95% CI: 4.0–12%) of patients. In those with diabetic neuropathy, altered (low and borderline) vitamin B12 level was 64% (95% CI: 47–78%) compared to 17% (95% CI: 10–26%) in patients without diabetic neuropathy (coefficient: −110.8; CI 95%: −165.8, −59.7). Those taking a higher metformin dose had lower levels of vitamin B12 (coefficient: −0.061; CI 95%: −0.09, −0.024). In addition, female patients had higher levels of vitamin B12 compared to men (coefficient: 49.1; CI 95%: 2.3–95). Conclusions Vitamin B12 deficiency is highly prevalent, especially in patients with diabetic neuropathy. In this study an inverse correlation was found between diabetic neuropathy and the plasma level of vitamin B12. Higher doses of metformin and male sex were factors related to lower levels of vitamin B12.

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