The Impact of Antibiotic Exposure during Prenatal and Infant Period on Childhood Overweight and Obesity: A Meta-Analysis of Population-Based Cohort Studies

2018 ◽  
Vol 2017 (1) ◽  
pp. 1078
Author(s):  
Yizhe Song ◽  
Tianjia Guan ◽  
Yuanli Liu
2018 ◽  
Vol 20 (6) ◽  
pp. 1508-1514 ◽  
Author(s):  
Sara H. Rasmussen ◽  
Sarita Shrestha ◽  
Lise G. Bjerregaard ◽  
Lars H. Ängquist ◽  
Jennifer L. Baker ◽  
...  

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Gwinyai Masukume ◽  
Sinéad M. O’Neill ◽  
Philip N. Baker ◽  
Louise C. Kenny ◽  
Susan M. B. Morton ◽  
...  

2020 ◽  
Vol 52 (2) ◽  
pp. 369-373 ◽  
Author(s):  
Jong-Myon Bae

PurposeA previous meta-analysis (MA) published in 2009 reported that excess body weight was associated with an increased risk of gastric cancer in non-Asians, but not in Asians. The aim was to conduct a meta-epidemiological MA (MEMA) to evaluate association between excess body weight and the risk of gastric cancer in Asian adults with using the proposed classification of weight by body mass index (BMI) in Asian adults.Materials and MethodsThe selection criteria were population-based prospective cohort studies that measured BMI of cohort participants and evaluated a risk of gastric cancer. Overweight group (OW) and obesity group (OB) were defined as 23.0-24.9 and ≥ 25.0, respectively. A group only showing results for BMI over 23.0 was defined as overweight and obesity group (OWB). Random effect model was applied if I<sup>2</sup> value was over 50%.ResultsAfter four new studies were added through citation discovery tools, seven cohort studies with 21 datasets were selected finally for MEMA. The I<sup>2</sup> value of OW, OB, and OWB were 76.1%, 83.5%, and 97.1%, respectively. Only OWB in men had a I<sup>2</sup> value below 50% (22.5%) and showed a statistical significance with inverse association (summary relative risk, 0.79; 95% confidence interval, 0.77 to 0.81).ConclusionThis MEMA supported the hypothesis that OW might be a protective factor in gastric cancer risk in Asian adults. It will be necessary to conduct additional cohort studies with lengthening follow-up periods and re-analyzing the effect of overweight and obesity classified by the Asian criteria.


Author(s):  
Sabrina G. M. O. Rocha ◽  
Hermano A. L. Rocha ◽  
Álvaro J. M. Leite ◽  
Márcia M. T. Machado ◽  
Ana C. Lindsay ◽  
...  

Childhood obesity is now an epidemic in many countries worldwide and is known to be a multifactorial condition. We aimed to examine the relationship of environmental, socioeconomic, and nutritional factors with childhood overweight and obesity. We conducted a population-based cross-sectional study of children from 2 to 6 years of age in Ceará, Brazil. Children’s nutritional status was assessed by body mass index (BMI) Z scores categorized as overweight and obesity. Ordinal logistic regression models were used to assess the relationship between the factors with overweight and obesity. A total of 2059 children participated, of which 50.4% were male. The mean age was 46 ± 17 months, with a prevalence of overweight and obesity of 12.0% (95% CI 10.7–13.6) and 8.0% (6.7–9.5), respectively. In multivariate analysis, the probability of childhood obesity increased as family income increased (adjusted hazard ratio (aHR) 0.6 (95% CI 0.37–0.95), p-value = 0.03). Moreover, families with fewer children had more than 30% fewer overweight children (aHR 0.68; 95% CI 0.48–0.96). Environmental, socioeconomic, and child nutritional factors were associated with overweight and obesity. The results provided could be used to design integrated interventions spanning from conception, or earlier, through the first years of life and may improve child nutritional outcomes.


Sign in / Sign up

Export Citation Format

Share Document