scholarly journals Diffuse Dermal Angiomatosis Manifestation of Underlying Severe Peripheral Vascular Disease

2020 ◽  
Author(s):  
Abu Baker Sheikh ◽  
Nismat Javed ◽  
Karl Stoltze
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Vascular Disease ◽  
Cardiovascular Risk Factors ◽  
Peripheral Vascular Disease ◽  
Vascular Disorder ◽  
Peripheral Vascular

Diffuse dermal angiomatosis is a benign vascular disorder suspected in patients with cardiovascular risk factors. We report the case of a 62-year-old woman with a non-healing hip wound but no significant cardiovascular risk factors, who was found to have diffuse dermal angiomatosis on biopsy leading to the diagnosis of severe peripheral vascular disease. Her wound healed after revascularization.

scholarly journals Peripheral Vascular Disease Risk Factors among Patients Undergoing Hemodialysis

2002 ◽  
Vol 13 (2) ◽  
pp. 497-503
Author(s):  
Ann M. O’Hare ◽  
Chi-yuan Hsu ◽  
Peter Bacchetti ◽  
Kirsten L. Johansen
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Vascular Disease ◽  
Cardiovascular Risk Factors ◽  
Peripheral Vascular Disease ◽  
The United States ◽  
Left Ventricular ◽  
Peripheral Vascular ◽  
Cross Sectional ◽  
Negatively Associated

ABSTRACT. Peripheral vascular disease (PVD) is common among patients undergoing hemodialysis, but little is known regarding the risk factors for PVD in this population. Data from waves 1, 3, and 4 of the United States Renal Data System Dialysis Morbidity and Mortality Study were used to examine cross-sectional associations of a range of conventional cardiovascular risk factors and uremia- or dialysis-related variables with PVD. Univariate and multivariate logistic regression models were developed using wave 3 and 4 data. Odds ratios for the multivariate model derived using wave 3 and 4 data were then compared with those obtained with the wave 1 data set. For both data sets, PVD was positively associated with the duration of dialysis (vintage) and malnourished status and was negatively associated with serum albumin and parathyroid hormone levels and predialysis diastolic BP. Kt/V was negatively associated with PVD in waves 3 and 4 but not in wave 1. PVD was associated with increasing age, white (versus non-white) race, male gender, diabetes mellitus, coronary artery disease, cerebrovascular disease, smoking, and left ventricular hypertrophy, as for the general population, but not with hypertension or hyperlipidemia. In conclusion, PVD among hemodialysis patients is associated with both dialysis-specific variables and most conventional cardiovascular risk factors other than hypertension and hyperlipidemia. Future studies should prospectively examine the association of these variables identified in cross-sectional analyses with the de novo development of PVD in this population.

Comparative Histopathology of Radial Artery Versus Internal Thoracic Artery and Risk Factors for Development of Intimal Hyperplasia and Atherosclerosis

Circulation ◽  
1999 ◽  
Vol 100 (suppl_2) ◽  
Author(s):  
Permyos Ruengsakulrach ◽  
Roger Sinclair ◽  
Masashi Komeda ◽  
Jai Raman ◽  
Ian Gordon ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Radial Artery ◽  
Morphometric Analysis ◽  
Intimal Hyperplasia ◽  
Internal Thoracic Artery ◽  
Peripheral Vascular ◽  
Luminal Narrowing ◽  
Intimal Thickness

Background —In this study, we examined the comparative histopathology, morphometry, and risk factors for the development of intimal hyperplasia and atherosclerosis in the radial artery (RA) and the internal thoracic artery (ITA). Methods and Results —Paired specimens of RAs and ITAs, obtained from 150 patients who underwent CABG, were evaluated with histopathology; 110 pairs of arteries were suitable for morphometric analysis. The severity of disease was evaluated on the basis of percentage of luminal narrowing, intimal thickness index, and intima-to-media ratio. Risk factors were determined with stepwise linear regression. Intimal hyperplasia was seen in 141 RAs (94%) and 103 ITAs (69%) ( P <0.001). Atherosclerosis was seen in 5% of RAs and 0.7% of ITAs ( P =0.04). Medial calcification was found only in RAs (20 of 150, 13.3%) ( P <0.001). Morphometric analysis showed that compared with ITAs, RAs had a significantly higher intimal area, medial area, percentage of luminal narrowing, intimal thickness index, and intima-to-media ratio (all P <0.001) Factors found to be significant ( P <0.05) predictors of the 3 severity indices of intimal hyperplasia, including atherosclerosis, in RAs were peripheral vascular disease, smoking, age, and diabetes. Risk factors for intimal hyperplasia in ITAs were age and smoking. Conclusions —The RA is more likely to have atherosclerosis, intimal hyperplasia, and medial calcification than the ITA. Morphometric analysis indices showed marked differences between the RA and the ITA. Care should be taken when selecting the RA as a conduit in CABG, particularly in patients who are elderly, diabetic, smoke, or have peripheral vascular disease.

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