scholarly journals Canine Serum Amyloid A (SAA) Measured by Automated Latex Agglutination Turbidimetry Is Useful for Routine Sensitive and Specific Detection of Systemic Inflammation in a General Clinical Setting

2013 ◽  
Vol 75 (4) ◽  
pp. 459-466 ◽  
Author(s):  
Michelle B. CHRISTENSEN ◽  
Rebecca LANGHORN ◽  
Amelia GODDARD ◽  
Eva B. ANDREASEN ◽  
Elena MOLDAL ◽  
...  
Keyword(s):  
Systemic Inflammation ◽  
Clinical Setting ◽  
Serum Amyloid A ◽  
Latex Agglutination ◽  
Serum Amyloid ◽  
Specific Detection ◽  
Amyloid A ◽  
Canine Serum

The Effect of Sedation, Oral Examination, and Odontoplasty on Systemic Inflammation as Measured by Serum Amyloid A in the Adult Performance Horse

2019 ◽  
Vol 36 (3) ◽  
pp. 198-201
Author(s):  
Sheri S. W. Birmingham ◽  
Rocky M. Mason
Keyword(s):  
Systemic Inflammation ◽  
Serum Amyloid A ◽  
Acute Phase Proteins ◽  
Systemic Disease ◽  
Oral Examination ◽  
Serum Amyloid ◽  
Amyloid A ◽  
Adult Performance ◽  
Normal Limits ◽  
Time Periods

Serum amyloid A (SAA) is one of the major acute phase proteins in horses. It serves as a marker for systemic inflammation and infection, as the concentration can increase 100- to even 1000-fold during systemic disease processes. The objective of this study was to evaluate the effect of sedation, oral examination, and odontoplasty on systemic inflammation as measured by SAA in the adult performance horse. This study included 32 clinically healthy adult performance horses. Blood samples were collected immediately prior to sedation, oral examination, and odontoplasty and 48 and 72 hours afterward. Serum amyloid A levels were measured directly after venipuncture using a commercially available stall-side lateral flow immunoassay test developed and validated for equine SAA levels. Serum amyloid A values were within normal limits for each of the time periods and there were no significant differences in SAA values between the time periods. The results of this study suggest that sedation, oral examination, and odontoplasty have no systemic inflammatory effects as measured by SAA.

scholarly journals A Rapid Method for Measuring Serum Amyloid a Protein by Latex Agglutination Nephelometric Immunoassay

1993 ◽  
Vol 30 (1) ◽  
pp. 72-76 ◽  
Author(s):  
Toshiyuki Yamada ◽  
Yasuhiro Nomata ◽  
Osamu Sugita ◽  
Masahiko Okada
Keyword(s):  
Rapid Method ◽  
Serum Amyloid A ◽  
Primary Standard ◽  
Density Lipoprotein ◽  
Latex Agglutination ◽  
Serum Amyloid ◽  
Normal Range ◽  
Amyloid A ◽  
Serum Amyloid A Protein ◽  
Good Agreement

Serum amyloid A protein (SAA) is a sensitive acute phase react ant. We developed a method for the rapid measurement of human SAA in serum by kinetic nephelometry of anti-SAA antibody-coated latex agglutination. Measurement takes less than 6 min using an automated analyser. Standardization of the assay employs SAA-enriched high density lipoprotein as the primary standard. The values determined by our new method and by conventional enzymeimmunoassay showed good agreement ( r = 0·988). The normal range was 0·17–10·0 mg/L [mean (SD)]. This rapid method should prove useful in clinical laboratories.

Serum Amyloid A in Healthy Female Bottlenose Dolphins (Tursiops truncatus) During and After Uncomplicated Pregnancy

2017 ◽  
Vol 43 (4) ◽  
pp. 417-420 ◽  
Author(s):  
Sarah N. Miller ◽  
Michelle Davis ◽  
Jorge A. Hernandez ◽  
Judy St. Leger ◽  
Carolyn Cray ◽  
...  
Keyword(s):  
Tursiops Truncatus ◽  
Serum Amyloid A ◽  
Bottlenose Dolphins ◽  
Serum Amyloid ◽  
Amyloid A ◽  
Uncomplicated Pregnancy ◽  
Healthy Female
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