scholarly journals The Mediating Effect of Depression on the Relationship between Cognitive Function and the Activities of Daily Living in Post-stroke Patient

Author(s):  
Ji Eun Kim ◽  
Hwee Wee

Purpose: This study aimed to identify the relationship between cognitive function and activities of daily living (ADL) in addition to the mediating effect exerted by depression on this relationship in post-stroke patients.Methods: A cross-sectional study was performed. A total of 182 patients were recruited from two general and three geriatric hospitals in South Korea between July 2017 and June 2018. Cognitive function, depression, and ADL measures were assessed after informed consent was obtained. Data obtained were analyzed using multiple regression and a simple mediation model that applies the PROCESS macro with a 95% bias-corrected bootstrap confidence interval (5,000 bootstrap resampling).Results: The covariates were sex, age, educational level, types of paralysis, and type of hospital. After controlling for the demographic covariates, cognitive function significantly accounted for the variance of ADL. It was also demonstrated that depression partially mediated the relationship between cognitive function and ADL in post-stroke patients.Conclusion: Cognitive function directly influences the ADL in post-stroke patients and indirectly influences it through depression. This suggests that strategies for improving depression in post-stroke patients should be considered while managing cognitive functioning for improving the ADL.

Author(s):  
Amin Ghaffari ◽  
Malahat Akbarfahimi ◽  
Bijan Forough

Aim and background: One of the most important psychological disorders that arise after a stroke for people with subsequent depression, which leads to reduced quality of life, optimal rehabilitation failure, loss of cognitive tasks and decrease the recovery process.In this study communication patterns of depression with cognitive, motor and function deficites in people with chronic stroke has been studied.Methods and materials: it is a pilot study of cross-sectional study, 40 patients with chronic stroke (more than 6 months) selected sampling method. depression (Beck Depression Inventory), cognition (attention test TMT-A & B and Wechsler memory), motor (Motorcity index), basic activities of daily living (Barthel scale) and instrumental activities of daily living (Lawton scale) were evaluated.Results: The results of the study revealed a significant positive correlation between post stroke depression with verbal memory(r=./386 ،P<./05), attention(r=./549 ،P<./05), motor status(r=./550 ،P<./05) and independence in activities of daily living(r=./653 ،P<./05)Conclusion: According to the findings, the study of factors affecting  post stroke depression(PSD) clinical and practical aspects are necessary. Cognitive rehabilitation programs with motor rehabilitation can reduce depression in patients with stroke in the direction of independence in activities of daily living and greater participation in society .    


2019 ◽  
Vol 35 ◽  
pp. 153331751987139 ◽  
Author(s):  
Daiki Ishimaru ◽  
Hiroyuki Tanaka ◽  
Yuma Nagata ◽  
Shinichi Takabatake ◽  
Takashi Nishikawa

Background: The authors examined associations between physical activity, cognitive function, activities of daily living, and behavioral and psychological dementia symptoms (BPSD) in severe and moderate dementia. Methods: A cross-sectional study was conducted to assess severe and moderate dementia groups according to the Clinical Dementia Rating. An actigraphy measured physical activity. Other measures included Mini-Mental State Examination, Cognitive Test for Severe Dementia, Hyogo Activities of Daily Living Scale, and Neuropsychiatric Inventory-Nursing Home. Results: Sixty-three participants were assessed (mean age = 89.3 ± 6.4). Physical activity was not associated with cognitive function among participants with severe dementia, although there was a trend-level association with cognitive function among those with moderate dementia. Physical activity was significantly associated with BPSD, specifically agitation/aggression symptoms, for participants with severe dementia, and there was a trend-level association with anxiety for participants with moderate dementia. Conclusions: Physical activity appears to be associated with BPSD among individuals in the advanced stages of dementia.


2021 ◽  
Vol 9 (4) ◽  
pp. 3979-3984
Author(s):  
Samuel SE ◽  
◽  
Senapathi P ◽  
Shetty S ◽  
◽  
...  

Background: Higher BMI has been often attributed with decline in cognitive function, mortality, and morbidity in elderly. However, few studies have reported high BMI as protective towards cognition and Activities of Daily Living (ADL). Accurate quantification of the role of BMI in the incidence of cognition and performance is desirable in the face of the increasing prevalence of individuals with overweight and obesity and prolonged life span in the population. This study aimed to investigate the association of BMI with cognition and ADL in community living elderly. Method: A cross sectional study was conducted among community living elderly. BMI and KATZ index scores were recorded from the respondents. Data were analyzed using SPSS version and a p value of less than 0.05 was considered statistically significant. Results: A total of 53 respondents enrolled in this study and was predominated by (54.7%) males and (45.30%) females. Karl Pearson correlation coefficient test found a positive correlation (r= 0.33) between BMI and Cognition and was found to be statistically significant (p<0.05). Also, it was observed that moderately positive correlation exists between BMI and ADL (r =0.64) and was found to be statistically very highly significant (p<0.001) Conclusion: This study concluded that among elderly, higher BMI values were associated with better performance in daily activities and lower cognitive impairment. KEY WORDS: Elderly, Body mass index, Activities of Daily Living, Cognition.


2020 ◽  
Vol 04 (5) ◽  
pp. 01-04
Author(s):  
Víctor Silverio

Aim: to determine if dynamic balance is related to activities of daily living (ADL) dependence in stroke patients. Methods: a cross-sectional study was carried out. The Barthel index (BI) was used to assess ADL dependence. The Timed Up and Go Test (TUG) and the Four Square Step Test (FSST) were used to evaluate dynamic balance. A Spearman correlation was used assuming a data abnormality in the performance of TUG and FSST and considering a significance of p<0.05. Results: 62 stroke patients were evaluated. The BI showed correlations with the performance of the TUG and the FSST. These correlations were also found between performance of both balance tests and ADLs, such as bathing, moving, and going up and down stairs. In contrast to TUG, correlations were estimated between the ADL related to dressing and the performance of the FSST. Conclusion: dynamic balance evaluated by the TUG and the FSST showed correlations with the ADL dependency in stroke patients.


BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e029221 ◽  
Author(s):  
Renly Lim ◽  
Lisa M Kalisch Ellett ◽  
Imaina S Widagdo ◽  
Nicole L Pratt ◽  
Elizabeth Ellen Roughead

ObjectiveTo test the association between use of medicines with anticholinergic or sedative properties and physical function, cognitive function, appetite and frailty.Design, setting and participantsThis cross-sectional study analysed baseline data collected as part of the Australian Longitudinal Study of Ageing, a population-based cohort of 2087 participants aged 65 years or over living in South Australia.Main outcome measuresPhysical function was measured at baseline using measures including hand grip strength, walking speed, chair stands, activities of daily living and instrumental activities of daily living (IADL). Cognitive function was measured using Mini-Mental State Examination. Appetite was measured using Center for Epidemiologic Studies Depression question 2. Frailty was measured using frailty index. The association between use of anticholinergics or sedatives and physical or cognitive function, appetite, or frailty was assessed using analysis of covariance and ordinal or binary logistic regression.ResultsAlmost half of the population were using anticholinergics or sedatives (n=954, 45.7%). Use of anticholinergics was significantly associated with poorer grip strength, slower walking speed, poorer IADL and poorer appetite. Use of sedatives was significantly associated with poorer grip strength, slower walking speed and poorer IADL. We found no significant association between medicine use and cognitive function. Users of anticholinergics or sedatives were significantly more likely to be frail compared with non-users.ConclusionUse of medicines with anticholinergic or sedative properties is significantly associated with poorer physical function, poorer appetite and increased frailty. Early identification of signs and symptoms of deterioration associated with medicine use is particularly important in older people so that worsening frailty and subsequent adverse events are prevented.


2016 ◽  
Vol 96 (2) ◽  
pp. 167-175 ◽  
Author(s):  
Naoto Fukutani ◽  
Hirotaka Iijima ◽  
Takahiko Fukumoto ◽  
Daisuke Uritani ◽  
Eishi Kaneda ◽  
...  

Background Increasing evidence highlights potential associations between varus thrust and health domains associated with knee osteoarthritis (OA). Objective The aim of this study was to investigate the association between varus thrust and 2 subcategories—“pain and stiffness” and “activities of daily living (ADL)”—of the Japanese Knee Osteoarthritis Measure (JKOM). Design This was a cross-sectional study. Methods In total, 296 outpatients with knee OA visiting orthopedic clinics were enrolled. The inclusion criteria were age ≥50 years, medial knee OA and Kellgren-Lawrence (K/L) grade ≥1 in one or both knees, and the ability to walk independently. Standard posterior-anterior knee radiographs were measured for varus alignment. Participants were video recorded while walking and were evaluated for the presence or absence of varus thrust. Pain and stiffness of the knee joint and ADL were evaluated using the JKOM. Multivariate regressions (outcomes: pain and stiffness and ADL; predictor variable: varus thrust) were performed. Results Varus thrust was present in 46 (16.2%) of 284 patients. Multivariate regression analyses demonstrated that varus thrust is independently associated with pain and stiffness, adjusted for age, sex, body mass index, K/L grade, and varus alignment (β=.17, P=.005). However, the association between varus thrust and ADL was not significant (β=.11, P=.058). Based on sensitivity analyses, including participants of K/L grade 1 had little influence on this analysis. Limitations Only 16.2% of participants had a varus thrust. Moreover, a cause-effect relationship between varus thrust and pain and stiffness remains unknown due to the cross-sectional design of this study. Conclusions Varus thrust was associated with pain and stiffness in patients with medial knee OA. However, the association between varus thrust and ADL did not reach significance.


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