scholarly journals THERAPEUTIC MANAGEMENT OF PATIENTS INFECTED WITH SARS-CoV-2 VIRUS - A REVIEW

2021 ◽  
Vol 2 ◽  
pp. 9-16
Author(s):  
Nicoleta Blebea ◽  
Gabriela Mitea

INTRODUCTION: Due to the rapid outbreak of the pandemic that causes SARS-CoV-2 infection and the increased rate of morbidity and mortality as a result of this new infection, the treatments pursued in therapy must have an increased potential to inhibit the replication of this virus. OBJECTIVES: The main objective of this article was to describe the most current drug therapies and their mechanisms of action used in the treatment of COVID-19. In this article, we have collected the latest information and multilingual international scientific discoveries about the treatment of COVID-19. RESULTS: Several compounds can be used to treat COVID-19 in order to reduce the duration of the disease and the rate of infection, to reduce the viral load, to prevent tissue damage, to stimulate the maturation of many cells, including immune cells in the human body and to reduce its severe symptoms. The most effective treatments were based on the antiviral drugs, antimalarial drugs, anti-inflammatory drugs, analgesics drugs, glycopeptide antibiotics, anticoagulants, vitamin C and vitamin D. The simplest and most direct approach to controlling SARS-CoV-2 outbreaks is the use of passive antibodies transferred from plasma to convalescent patients. Recently, studies have been completed for several vaccines that are approved against SARS-CoV-2. CONCLUSION: Scientists around the world are collaborating and innovating to make tests, treatments and vaccines available to the public that will save lives collectively and end this pandemic.

2021 ◽  
Vol 4 (2) ◽  
pp. 189-196
Author(s):  
Marten Umbu Nganji ◽  
Lusia Danga Lewu ◽  
Uska Peku Jawang ◽  
Yonce Melyanus Killa ◽  
Sri Ita Tarigan

Abstract: Moringa leaves can be processed in various food and beverage products such as clear vegetables, juice, omelette, chips, nastar, donuts, bakwan and Moringa leaf noodles. In addition, Moringa leaves can be processed as herbal drinks. Currently, with the covid-19 pandemic conditions around the world, many alternative herbal ingredients are consumed by the public to increase body nutrition in order to prevent transmission of the virus, one of which is Moringa leaves. Moringa plants are high in nutrients, such as vitamin C, calcium, vitamin A, potassium, and protein. The purpose of implementing this PkM activity is to provide information and, to provide assistance to the community in utilizing Moringa plants to prevent Covid-19, as well as to improve community skills in making Moringa herbal drink to prevent Covid-19. This PkM was held at the Ori Angu Farmers Group in Pambotanjara Village, with a series of activities including the socialization of the importance of Moringa leaves, the preparation of raw materials for making herbal moringa drinks, and the practice of manufacturing Moringa leaf herbal drink products. The results of this activity were the socialization of the use of Moringa leaves as a way to increase immunity in order to prevent viruses and the practice of making Moringa leaf tea with members of farmer groups, students and lecturers at the Ori Angu Farmer Group, Pambotanjara Village.Keywords: herbal drink; moringa leaves; prevents covid-19Abstrak: Daun kelor dapat diolah dalam berbagai produk makanan dan minuman seperti sayur bening, juice, omelet, keripik, nastar, donat, bakwan dan mie daun kelor. Selain itu, daun kelor dapat diolah sebagai minuman herbal. Saat ini, dengan adanya kondisi pandemik covid-19 di seluruh dunia, banyak alternatif bahan herbal yang dikonsumsi oleh masyarakat untuk menambah nutrisi tubuh agar dapat mencegah terjadinya penularan virus tersebut, salah satunya adalah daun kelor. Tanaman kelor memiliki nutrisi tinggi, seperti vitamin C, kandungan kalsium, vitamin A, kandungan potasium, dan protein. Tujuan pelaksanaan kegiatan PkM ini adalah untuk memberikan informasi dan, melakukan pendampingan kepada masyarakat dalam memanfaatkan tanaman kelor untuk mencegah covid-19, serta meningkatkan keterampilan masyarakat dalam pembuatan minuman herbal daun kelor dalam mencegah covid-19. PkM ini dilaksanakan di Kelompok Tani Ori Angu Desa Pambotanjara dengan runtutan kegiatan adalah sosialisasi pentingnya daun kelor, persiapan bahan baku pembuatan minuman herbal daun kelor, dan praktik pembuatan produk minuman herbal daun kelor. Hasil dari kegiatan ini adalah terlaksananya sosialisasi pemanfaatan daun kelor sebagai salah satu cara menambah imunitas tubuh dalam rangka mencegah virus dan dilaksanakannya praktik pembuatan teh daun kelor bersama anggota kelompok tani, mahasiswa dan dosen di Kelompok Tani Ori Angu Desa Pambotanjara.Kata kunci: daun kelor; mencegah covid-19; minuman herbal


Author(s):  
Colleen Henrichsen

A medical resident was on duty at New York Hospital one night in 1979 when a 27-year-old security guard was admitted with a rare form of pneumonia. As inexperienced as the resident was, he knew that this very rare condition was usually diagnosed only in people with a history of cancer, organ transplantation, or other conditions involving immune system suppression. This otherwise healthy young man had none of those. Weeks later, when the resident presented this case at inner-city rounds, a number of hands shot up. These clinicians had seen similar cases. The resident's report of this New York City outbreak was one of three that formed the basis for the first published report of the disease we would come to know as AIDS. Three years later, this physician, Dr. Henry Masur, arrived at the National Institutes of Health where he joined established NIH researchers already anxiously trying to understand this deadly new condition. At key communications offices on the NIH campus, phones were ringing incessantly. Reporters all around the world wanted to know what NIH was doing about it. As public communicators, we were learning about the disease along with the researchers. Why did it seem to disproportionately affect gay men? Why were people with the disease dying from ordinary infections? We were learning the answers to these questions as they unfolded, translating what we learned into plain English, and getting the information out to the public. A prominent AIDS researcher came into the office of one of my colleagues, sat next to her, and made a simple drawing of how immune cells appeared to be affected by the new virus, explaining it to her at the same time scientists themselves were just beginning to understand it. Dr. Masur is now chief of the Critical Care Medicine Department of the NIH Clinical Center. I covered his account of his first meeting with an AIDS patient for an NIH employee newsletter when he delivered the NIH Astute Clinician Lecture in 2002, which honors scientists who observe and investigate unusual clinical occurrences.


2020 ◽  
Vol 20 (8) ◽  
pp. 583-592 ◽  
Author(s):  
Yu-Qing Tang ◽  
Qian Ye ◽  
He Huang ◽  
Wei-Yi Zheng

: Malaria is one of the three most deadly infectious diseases in the world and seriously endangers human health and life. To reduce the public health burden of this disease, scientists have focused on the discovery and development of effective antimalarial drugs, from quinine and chloroquine to antifolates and artemisinin and its derivatives, which all play a profound role in the treatment of malaria. However, drugresistant strains of Plasmodium falciparum have emerged due to frequent use of antimalarials and have become increasingly resistant to existing antimalarial drugs, causing disastrous consequences in the world. In particular, artemisinin resistance is of greatest concern which was reported in 2008. Resistance to artenisinins has been a major obstacle for malaria control, and current efforts to curb artemisinin resistance have not been successful. Based on the current situation, it is urgent to develop more effective new antimalarials with distinct targets from conventional antimalarials in the world, which could facilitate to minimize the phenomenon of drug resistance. This review aims to summarize different kinds of antimalarial therapeutic efficacy, mechanisms of action and resistance, and proposes new solutions aiming towards further improvement of malaria elimination.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Sitirahmadani Lubis ◽  
M. ALIF ALFARUQI ◽  
Aan Kriswana Fasha ◽  
Nurul Intan Manurung

Moringa leaves can be processed in various food and beverage products such as clear vegetables, juice, omelette, chips, nastar, donuts, bakwan and Moringa leaf noodles. In addition, Moringa leaves can be processed as herbal froods. Currently, with the covid-19 pandemic conditions around the world, many alternative herbal ingredients are consumed by the public to increase body nutrition in order to prevent transmission of the virus, one of which is Moringa leaves. Moringa plants are high in nutrients, such as vitamin C, calcium, vitamin A, potassium, and protein. The purpose of implementing this KKN activity is to provide information and, to provide assistance to the community in utilizing Moringa plants to prevent Covid-19, as well as to improve community skills in making Moringa herbal food to prevent Covid-19. This KKN was held at the in Air Joman Village, with a series of activities including the socialization of the importance of Moringa leaves, the preparation of raw materials for making herbal moringa foods, and the practice of manufacturing Moringa leaf herbal food products. The results of this activity were the socialization of the use of Moringa leaves as a way to increase immunity in order to prevent viruses and the practice of making Moringa leaf tea with village head, students and lecturers at Air Joman Village. Keywords: herbal food; moringa leaves; prevents covid-19


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 425-429
Author(s):  
Roselin C ◽  
Parameshwari S

The world is now in the state of contingency and is facing one common enemy, COVID 19. Front developed countries to the developing and under developed countries, all are fighting against this common enemy which is a virus that is 0.125 microns ( 1 25 nm) with the size ranging from 0.06 to 0.14 microns. The world is now looking for a vaccine to prevent the infection, while the need of the hour is to boost the immunity of individuals against the disease through readily available nutrients. With the increase in incidence of the COVID-19 pandemic, scientists to common public have started to ponder the ways out of it, while boosting the immunity has become the only resolve as no vaccine has been invented until date. It is obvious that there is a correlation between nutrition and immune system; it is a common understanding that people who are well-nourished have a better immunity compared to poorly nourished people with a weak immunity. It is to be noted that people suffering from chronic diseases and elderly will have a weak immunity and are more prone to any disease let alone COVID-19. Though general immunity can be boosted through vitamin C, zinc and other micronutrients, vitamin D is required to boost overall immunity and also strengthen lungs. This review aims at laying emphasis on the need of vitamin D in strengthening immunity against the deadly common enemy COVlD- 19.


2019 ◽  
Vol 26 (2) ◽  
pp. 227-252
Author(s):  
Deborah Solomon

This essay draws attention to the surprising lack of scholarship on the staging of garden scenes in Shakespeare's oeuvre. In particular, it explores how garden scenes promote collaborative acts of audience agency and present new renditions of the familiar early modern contrast between the public and the private. Too often the mention of Shakespeare's gardens calls to mind literal rather than literary interpretations: the work of garden enthusiasts like Henry Ellacombe, Eleanour Sinclair Rohde, and Caroline Spurgeon, who present their copious gatherings of plant and flower references as proof that Shakespeare was a garden lover, or the many “Shakespeare Gardens” around the world, bringing to life such lists of plant references. This essay instead seeks to locate Shakespeare's garden imagery within a literary tradition more complex than these literalizations of Shakespeare's “flowers” would suggest. To stage a garden during the sixteenth and seventeenth centuries signified much more than a personal affinity for the green world; it served as a way of engaging time-honored literary comparisons between poetic forms, methods of audience interaction, and types of media. Through its metaphoric evocation of the commonplace tradition, in which flowers double as textual cuttings to be picked, revised, judged, and displayed, the staged garden offered a way to dramatize the tensions produced by creative practices involving collaborative composition and audience agency.


2021 ◽  
Vol 11 (SPL1) ◽  
pp. 1585-1592
Author(s):  
Roshna Sukhdeoji Bhutada

Nowadays, due to Covid-19 pandemic circumstance, numerous individuals are Staying from home. Understudy is additionally concern with the online class from home, because of which all physical movement of all individual has been stopped. Medoroga is one of the dominating metabolic problems and driving reason for mortality. Numerous patients with Covid infection 2019 (COVID-19) have identified with the metabolic disorder during the lockdown. The general wellbeing proposes (Work from Home, requests, gyms, terminations of garden and wellness focuses) to forestall Covid-19 spread can possibly decrease day by day physical movement. Ideas of Agni, Prakriti, strategy for victualing ought to be given equivalent consideration while choosing ones dietary and exercise routine to turn away/control Medoroga (STHAULYA). Organizing of diet is generally important to support insusceptibility. According to numerous investigates to give valuable pabulum which contains Zinc, Vitamin C, Vitamin D and invulnerability. It is practically equivalent to Medoroga referenced in Ayurveda compositions. Strick likeness outwardly inspected in both customary arrangement of medication and Ayurveda while portraying its causative components, outcomes and preventive part of exercise and diet in its administration. Striking is outwardly analyzed in both Traditional arrangements of medication and Ayurveda depicting its causative factors, and preventive capacity of movement and diet in its pandemic Covid-19.


Author(s):  
Khaled Asfour

In Vitruvius’ treatise, what makes good architecture is its ability to communicate to the public particular messages that reflects the program of the building with spaces and components arranged in an orderly way. According to Vitruvius these messages when acknowledges by the public the building posses strong character. This research discusses this idea by reflecting on the 1895 competition of the Egyptian Museum project. Marcel Dourgnon, the French architect of the winning scheme, showed profound understanding of character resulting in a building that had positive vibe with the local community.  Today Vitruvius’ idea is still living with us. Norman Foster succeeded in upgrading the British Museum in a way that addressed all cultures of the world through his grand atrium design.  Similarly, Emad Farid and Ramez Azmy revived the presence of the Egyptian Museum in public cognition.  Spatial experience that evokes similar perceptions to all its visitors is a timeless piece that transcends cultural boundaries.


2019 ◽  
Vol 47 (3) ◽  
pp. 80-91
Author(s):  
V. G. Neiman

The main content of the work consists of certain systematization and addition of longexisting, but eventually deformed and partly lost qualitative ideas about the role of thermal and wind factors that determine the physical mechanism of the World Ocean’s General Circulation System (OGCS). It is noted that the conceptual foundations of the theory of the OGCS in one form or another are contained in the works of many well-known hydrophysicists of the last century, but the aggregate, logically coherent description of the key factors determining the physical model of the OGCS in the public literature is not so easy to find. An attempt is made to clarify and concretize some general ideas about the two key blocks that form the basis of an adequate physical model of the system of oceanic water masses motion in a climatic scale. Attention is drawn to the fact that when analyzing the OGCS it is necessary to take into account not only immediate but also indirect effects of thermal and wind factors on the ocean surface. In conclusion, it is noted that, in the end, by the uneven flow of heat to the surface of the ocean can be explained the nature of both external and almost all internal factors, in one way or another contributing to the excitation of the general, or climatic, ocean circulation.


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