scholarly journals Influence of motor impairment on exercise capacity and quality of life in patients with Parkinson disease

2021 ◽  
Vol 17 (4) ◽  
pp. 241-246
Author(s):  
Hélcio Kanegusuku ◽  
Raphael M. Ritti-Dias ◽  
Pâmela Yuki Igarasi Barbosa ◽  
Erica Tardelli das Neves Guelfi ◽  
Erika Okamoto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson Disease ◽  
Healthy Subject ◽  
Exercise Capacity ◽  
Motor Impairment ◽  
Stage Iv ◽  
Summary Index ◽  
The Impact ◽  
Disease Questionnaire

This study evaluated the impact of motor impairment (MI) on exercise capacity and quality of life in patients with Parkinson disease (PD). One hundred ninety-two patients (≥50 years old) were divided according to the Hoehn and Yahr stages in: mild (stage I), mild to moderate (stage II), moderate (stage III), and advanced MI (stage IV). Exercise capacity (6-min walk test [6MWT]) and quality of life (Parkinson’s Disease Questionnaire [PDQ-39]) were obtained. In this context, 6MWT was progressively worse with increasing the severity of MI (P<0.01). Patients with advanced MI achieved 39% of predicted 6MWT of healthy subject, while subjects with mild MI achieved 83% of healthy subject (P<0.01). In addition, patients with advanced MI presented higher (i.e., worse) PDQ-39 scores in summary index, cognition, mobility and activities of daily live domains compared to other groups (P<0.01). Patients with moderate MI also presented worse scores in PDQ-39 summary index, mobility and activities of daily live domains in comparison with mild MI patients (P<0.01). Higher MI was correlated with worse exercise capacity (6MWT: r=-0.46, P<0.01), with worse PDQ-39 summary index and the mobility and activities of daily live domains scores (r=0.38, r=0.46, and r=0.43, P<0.01). In conclusion, MI is related to lower exercise capacity and quality of life (i.e., PDQ-39 summary index and mobility and activities of daily live domains) in patients with PD.

Psychophysical functioning and quality of life in 94 patients affected by oropharyngeal cancer and treated with different therapeutic approaches.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 6039-6039
Author(s):  
Fulvia Pedani ◽  
Mario Airoldi ◽  
Massimiliano Garzaro ◽  
Riccardo Torta ◽  
Luca Raimondo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychological Functioning ◽  
Depression Scale ◽  
Stage Iv ◽  
Stage Iii ◽  
Lower Percentage ◽  
Anxiety And Depression ◽  
Anxiety Depression ◽  
The Impact

6039 Background: The treatment of oropharyngeal squamous cell carcinomas (OSCC) may heavily affect patient’s quality of life (QoL). Aim of our study was the evaluation of the impact of different treatments on physical and psychological functioning and on QoL of patients affected by stage III-IV disease. Methods: The enrolled sample was composed by 94 OSCC patients divided into 3 subgroups based on treatment modalities: surgery + adjuvant radiotherapy (S + RT: 30 patients), exclusive concomitant chemo-radiotherapy (CT + RT: 30 patients) and exclusive chemotherapy (CT) in 34 patients not suitable for surgery and/or radiotherapy. Psycho-oncological assessment included: Hospital Anxiety Depression Scale (HADS), Montgomery-Asberg Depression Scale (MADRS), Mini-Mental Adjustment to Cancer scale (MINI-MAC), EORTC QLQ C-30 questionnaire with the specific module Head and Neck 35 (H&N35). Results: The 60 patients primarily treated with S + RT or CT + RT presented superimposeable clinical and tumour characteristics while those treated with exclusive CT were affected by stage IV disease and in the 90% of cases underwent to previous treatment exclusive or combined treatment such as surgery, radiotherapy and chemotherapy. In the following table, data about physical and psychological functioning and on QoL of the 3 subgroups of patients are summarized. Conclusions: In stage III-IV OSCC treatments have a strong influence on QoL and coping styles. Patients treated with CT + RT were characterized by a lower percentage of self-reported anxiety and depression and higher EORTC Global QoL score. More than one third of patients treated with S + RT had overt symptoms of anxiety and depression. Stage IV patients treated with palliative CT had elevated level of anxiety, depression and low quality of life. Auto-evaluation is less effective in depression assessment. The role of concomitant psychological supportive care should be evaluated in these patients treated with different approaches. [Table: see text]

scholarly journals P141 The impact of exacerbations on muscle force, exercise capacity and quality of life in adults with cystic fibrosis

2018 ◽  
Vol 17 ◽  
pp. S99
Author(s):  
F. Pyl ◽  
E. Van Braeckel ◽  
F. De Baets ◽  
P. Calders ◽  
S. Bernaert ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Exercise Capacity ◽  
Muscle Force ◽  
The Impact

scholarly journals Exercise-based cardiac rehabilitation improves exercise capacity and health-related quality of life in people with atrial fibrillation: a systematic review and meta-analysis of randomised and non-randomised trials

Open Heart ◽  
2018 ◽  
Vol 5 (2) ◽  
pp. e000880 ◽  
Author(s):  
Neil A Smart ◽  
Nicola King ◽  
Jeffrey D Lambert ◽  
Melissa J Pearson ◽  
John L Campbell ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Exercise Capacity ◽  
Symptom Burden ◽  
Health Related Quality ◽  
Randomised Trials ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Impact

ObjectiveThe aim of this study was to undertake a contemporary review of the impact of exercise-based cardiac rehabilitation (CR) targeted at patients with atrial fibrillation (AF).MethodsWe conducted searches of PubMED, EMBASE and the Cochrane Library of Controlled Trials (up until 30 November 2017) using key terms related to exercise-based CR and AF. Randomised and non-randomised controlled trials were included if they compared the effects of an exercise-based CR intervention to a no exercise or usual care control group. Meta-analyses of outcomes were conducted where appropriate.ResultsThe nine randomised trials included 959 (483 exercise-based CR vs 476 controls) patients with various types of AF. Compared with control, pooled analysis showed no difference in all-cause mortality (risk ratio (RR) 1.08, 95% CI 0.77 to 1.53, p=0.64) following exercise-based CR. However, there were improvements in health-related quality of life (mean SF-36 mental component score (MCS): 4.00, 95% CI 0.26 to 7.74; p=0.04 and mean SF-36 physical component score: 1.82, 95% CI 0.06 to 3.59; p=0.04) and exercise capacity (mean peak VO2: 1.59 ml/kg/min, 95% CI 0.11 to 3.08; p=0.04; mean 6 min walk test: 46.9 m, 95% CI 26.4 to 67.4; p<0.001) with exercise-based CR. Improvements were also seen in AF symptom burden and markers of cardiac function.ConclusionsExercise capacity, cardiac function, symptom burden and health-related quality of life were improved with exercise-based CR in the short term (up to 6 months) targeted at patients with AF. However, high-quality multicentre randomised trials are needed to clarify the impact of exercise-based CR on key patient and health system outcomes (including health-related quality of life, mortality, hospitalisation and costs) and how these effects may vary across AF subtypes.

A Randomized Controlled Trial to Investigate the Impact of Tango Argentino versus Tai Chi on Quality of Life in Patients with Parkinson Disease: A Short Report

2019 ◽  
Vol 26 (6) ◽  
pp. 398-403 ◽  
Author(s):  
Désirée Poier ◽  
Daniela Rodrigues Recchia ◽  
Thomas Ostermann ◽  
Arndt Büssing
Keyword(s):  
Quality Of Life ◽  
Pilot Study ◽  
Parkinson Disease ◽  
Tai Chi ◽  
Clinical Care ◽  
Well Being ◽  
Short Report ◽  
Randomized Controlled ◽  
The Impact

Objectives: Parkinson disease (PD) is a neurodegenerative disorder with increasing impairments in disease progression. The aim of the pilot study was to investigate the influence of Tango argentino on the quality of life of people with PD compared to Tai Chi. Design, Setting, Interventions: In the two-arm, randomized controlled pilot study, patients with PD received a 10-week Tango argentino or Tai Chi intervention (once per week, 60 min each). Main Outcome Measures: The outcome parameters were assessed at three time points (after the 1st course, after the 5th course, and after the 10th course) using standardized instruments, i.e., Parkinson’s Disease Questionnaire-39 (PDQ-39), Brief Multidimensional Life Satisfaction Scale (BMLSS), Inner Congruence with Practices (ICPH). Results: Overall, 14 patients and their partners received Tango argentino (9 male, 5 female; mean age: 69 ± 8 years) and 15 received Tai Chi (3 male, 12 female; mean age: 69 ± 11 years). Four patients in each group were lost during the trial. No improvements were found in both groups for all outcomes. Patients in the tango group reported better emotional well-being (p = 0.039) after 10 weeks of intervention compared to the Tai Chi group. Conclusions: Further studies are needed taking into account findings from this study to improve recruitment and attrition of patients during the trial and to justify the potential implementation of Tango argentino into clinical care.

scholarly journals Virtual visits for Parkinson disease

2017 ◽  
Vol 7 (4) ◽  
pp. 283-295 ◽  
Author(s):  
Ryan E. Korn ◽  
Aparna Wagle Shukla ◽  
Maya Katz ◽  
H. Tait Keenan ◽  
Steven Goldenthal ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson Disease ◽  
Specialty Care ◽  
Small Scale ◽  
Improve Quality ◽  
Future Care ◽  
Virtual Visits ◽  
Disease Questionnaire

AbstractBackground:Previous small-scale studies have demonstrated the feasibility of providing remote specialty care via virtual visits. We assessed the feasibility and benefits of a one-time consultation between a remote Parkinson Disease (PD) specialist and an individual with PD at home on a larger scale.Methods:We conducted a multicenter noncontrolled cohort of virtual visits administered over videoconferencing between remote PD specialists and individuals with PD in their home. Specialists performed a patient history and a PD-specific physical examination and provided recommendations to patients and their local physicians. The primary outcome measures were feasibility, as measured by the proportion of visits completed as scheduled, and the 6-month change in quality of life, as measured by the Parkinson's Disease Questionnaire 39. Additional outcomes included satisfaction with visits and interest in future virtual visits.Results:A total of 277 participants from 5 states enrolled, 258 participants completed virtual visits with 14 different physicians, and 91% of visits were completed as scheduled. No improvement in quality of life was observed at 6 months (0.4-point improvement; 95% confidence interval −1.5 to 0.6; p = 0.39). Overall satisfaction with virtual visits was high among physicians (94% satisfied or very satisfied) and patients (94% satisfied or very satisfied), and 74% of participants were interested in receiving future care via virtual visits.Conclusions:Providing specialty care remotely into the homes of individuals with PD is feasible, but a one-time visit did not improve quality of life. Satisfaction with the visits was high among physicians and patients, who were interested in receiving such care in the future.Classification of evidence:This study provides Class IV evidence that for patients with PD, remote specialty care is feasible but does not improve quality of life.Clinicaltrials.gov identifier:NCT02144220.

scholarly journals The Impact of Deep Brain Stimulation on the Cognitive Ability of Patients with Parkinson Disease

2020 ◽  
Vol 9 (3) ◽  
pp. 69
Author(s):  
Kuo Liu
Keyword(s):  
Quality Of Life ◽  
Deep Brain Stimulation ◽  
Parkinson Disease ◽  
Cognitive Ability ◽  
Brain Stimulation ◽  
Positive Effects ◽  
The Impact ◽  
Stn Dbs ◽  
Deep Brain

<p>Deep Brain Stimulation, especially STN-DBS, is one of the most prevalent treatments for the Parkinson’s Disease. Previous researches already showed its positive effects on the general conditions of the patients but lack evaluation of its influence on the cognitive ability of the patients. A comparison in the effect of DBS and surgical lesioning procedures can determine DBS’s influence on the quality of life and confirm whether it is the most optimal treatment. This proposal reviewed previous researches about the influence of STN-DBS and proposed a study on its influence of patients’ cognitive ability.</p>

scholarly journals PREDICTING THE EQ-5D FROM THE PARKINSON'S DISEASE QUESTIONNAIRE PDQ-8 USING MULTI-DIMENSIONAL BAYESIAN NETWORK CLASSIFIERS

2014 ◽  
Vol 26 (01) ◽  
pp. 1450015 ◽  
Author(s):  
Hanen Borchani ◽  
Concha Bielza ◽  
Pablo Martinez-Martin ◽  
Pedro Larrañaga
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Bayesian Network ◽  
Bayesian Network Classifiers ◽  
Generic Measures ◽  
The Impact ◽  
Disease Questionnaire ◽  
Parkinson’S Disease Questionnaire

The impact of the Parkinson's disease and its treatment on the patients' health-related quality of life can be estimated either by means of generic measures such as the european quality of Life-5 Dimensions (EQ-5D) or specific measures such as the 8-item Parkinson's disease questionnaire (PDQ-8). In clinical studies, PDQ-8 could be used in detriment of EQ-5D due to the lack of resources, time or clinical interest in generic measures. Nevertheless, PDQ-8 cannot be applied in cost-effectiveness analyses which require generic measures and quantitative utility scores, such as EQ-5D. To deal with this problem, a commonly used solution is the prediction of EQ-5D from PDQ-8. In this paper, we propose a new probabilistic method to predict EQ-5D from PDQ-8 using multi-dimensional Bayesian network classifiers. Our approach is evaluated using five-fold cross-validation experiments carried out on a Parkinson's data set containing 488 patients, and is compared with two additional Bayesian network-based approaches, two commonly used mapping methods namely, ordinary least squares and censored least absolute deviations, and a deterministic model. Experimental results are promising in terms of predictive performance as well as the identification of dependence relationships among EQ-5D and PDQ-8 items that the mapping approaches are unable to detect.

scholarly journals The Influence of Digestive Dysfunctions on Quality of Life in Parkinson Disease

2019 ◽  
Vol 70 (5) ◽  
pp. 1667-1670
Author(s):  
Oana Criciotoiu ◽  
Iulia-Diana Stanca ◽  
Daniela-Gabriela Glavan ◽  
Roxana Mirela Latea ◽  
Adrian Mita ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastrointestinal Tract ◽  
Parkinson Disease ◽  
Poor Quality ◽  
Motor Symptoms ◽  
Yahr Scale ◽  
Severity Of The Disease ◽  
The Impact ◽  
Non Motor Symptoms

As a part of non-motor symptoms in Parkinson�s disease (PD), the dysfunctions of the gastrointestinal tract are frequent, being a major complain in the majority of the patients. The aim of our study was to assess the impact of digestive dysfunctions on quality of life in Parkinson�s disease. We included in this study 60 patients with PD, with a disease severity which varied between 2 and 5 on Hoehn and Yahr Scale. Our results showed a low correlation between digestive dysfunctions and the severity of the disease, but a statistically significant correlation between quality of life and the stage of the disease. Also, we observed a statistically significant correlation between digestive dysfunctions and quality of life. Our study revealed that the frequency of digestive dysfunction has correlated with a poor quality of life in any stage of the disease.

scholarly journals Perceptions of Individuals with Parkinson’s Disease about Quality of Life

2018 ◽  
Vol 16 (2) ◽  
pp. 262
Author(s):  
Aline Aparecida Foppa ◽  
Claudia Marcela Vargas-Peláez ◽  
Fabíola Bagatini Buendgens ◽  
Clarice Chemello ◽  
Mariana Piva Fleury Charmillot ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Parkinson Disease ◽  
Calidad De Vida ◽  
Disease Questionnaire

Introducción: la enfermedad de Parkinson es una patología neurodegenerativa, que se mani esta por signos y síntomas motores y no motores, que comprometen la calidad de vida de los pacientes. El Parkinson Disease Questionnaire (pdq-39) es el instrumento más utilizado para evaluar la calidad de vida en pacientes con esta enfermedad. Los objetivos del trabajo fueron identificar los aspectos relacionados con la Calidad de Vida desde la perspectiva de los pacientes, compararlos con los aspectos considerados por el pdq-39 y describir las estrategias adoptadas por los pacientes para superar las di cultades. Materiales y métodos: estudio cualitativo, descriptivo. Se realizó un grupo focal con seis pacientes. Los datos fueron analizados usando el método de análisis de contenido. Resultados: aspectos relacionados a todos los dominios del pdq-39 fueron mencionados por los pacientes, destacándose aquellos relacionados con las limitaciones de la movilidad y el desarrollo de actividades diarias, y aspectos relacionados con el bienestar emocional. No obstante, algunos aspectos considerados en el dominio movilidad del pdq-39 no fueron mencionados, y fueron detectadas limitaciones del dominio bienestar emocional. Los pacientes diseñan diversas estrategias para superar las di cultades, en las que el soporte social es importante. Conclusión: conocer y re exionar sobre las percepciones de persona con Enfermedad de Parkinson so- bre su calidad de vida contribuye para la comprensión de la enfermedad y auxilia la propuesta de intervenciones clínicas adecuadas para lograr el cuidado integral. Se sugiere la revisión y adaptación del pdq-39 al contexto actual, los avances tecnológicos y de conocimientos sobre la Enfermedad de Parkinson.

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