Psychophysical functioning and quality of life in 94 patients affected by oropharyngeal cancer and treated with different therapeutic approaches.

6039 Background: The treatment of oropharyngeal squamous cell carcinomas (OSCC) may heavily affect patient’s quality of life (QoL). Aim of our study was the evaluation of the impact of different treatments on physical and psychological functioning and on QoL of patients affected by stage III-IV disease. Methods: The enrolled sample was composed by 94 OSCC patients divided into 3 subgroups based on treatment modalities: surgery + adjuvant radiotherapy (S + RT: 30 patients), exclusive concomitant chemo-radiotherapy (CT + RT: 30 patients) and exclusive chemotherapy (CT) in 34 patients not suitable for surgery and/or radiotherapy. Psycho-oncological assessment included: Hospital Anxiety Depression Scale (HADS), Montgomery-Asberg Depression Scale (MADRS), Mini-Mental Adjustment to Cancer scale (MINI-MAC), EORTC QLQ C-30 questionnaire with the specific module Head and Neck 35 (H&N35). Results: The 60 patients primarily treated with S + RT or CT + RT presented superimposeable clinical and tumour characteristics while those treated with exclusive CT were affected by stage IV disease and in the 90% of cases underwent to previous treatment exclusive or combined treatment such as surgery, radiotherapy and chemotherapy. In the following table, data about physical and psychological functioning and on QoL of the 3 subgroups of patients are summarized. Conclusions: In stage III-IV OSCC treatments have a strong influence on QoL and coping styles. Patients treated with CT + RT were characterized by a lower percentage of self-reported anxiety and depression and higher EORTC Global QoL score. More than one third of patients treated with S + RT had overt symptoms of anxiety and depression. Stage IV patients treated with palliative CT had elevated level of anxiety, depression and low quality of life. Auto-evaluation is less effective in depression assessment. The role of concomitant psychological supportive care should be evaluated in these patients treated with different approaches. [Table: see text]

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Impact of Anxiety and Depression on Quality of Life among Patients Undergoing Hemodialysis: A Scoping Review

Evidence-Based Nursing Research ◽

10.47104/ebnrojs3.v2i3.134 ◽

2020 ◽

Vol 2 (3) ◽

pp. 14

Author(s):

Fatima I. AlNashri ◽

Hayfa H. Almutary ◽

Elham A. Al Nagshabandi

Keyword(s):

Quality Of Life ◽

Scoping Review ◽

Short Form ◽

Hemodialysis Patients ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Life Threatening ◽

Anxiety Depression ◽

The Impact

Context: Chronic kidney disease (CKD) is a life-threatening problem of global concern. Living with CKD is associated with many psychological problems, including depression and anxiety, which can directly or indirectly affect the quality of life. Only one review in the existing literature has assessed these associations among CKD patients using different dialysis modalities. However, the experience of these symptoms could be higher among patients on hemodialysis therapy. In this purview, there is a need to narrow the previous work to be more focused on hemodialysis patients. Aim: This scoping review aims to determine the gaps in the knowledge about the impact of anxiety and depression concerning QOL among people undergoing hemodialysis. Methods: The studies selected were those examined the relationships between depression or/and anxiety with quality of life in adult patients on hemodialysis. The CINAHL, MEDLINE, and Pub Med databases were searched for literature published between January 2012 and December 2019. The quality of the included studies was also apprised. Eleven studies met the inclusion criteria. Results: Six studies examined the impact of depression and anxiety on the quality of life. Five studies identified from the review have examined the relationships between depression and quality of life. It was established that the prevalence of anxiety and depression was high among hemodialysis patients, and the same was associated with low quality of life. Conclusion: The literature review highlights the negative associations between anxiety, depression, and quality of life among hemodialysis patients. It is, therefore, essential to screen hemodialysis patients frequently for anxiety and depression using a short-form questionnaire. This screening would allow for providing early interventions, and the potential deterioration of quality of life could be prevented. Further longitudinal studies are needed to assess these relationships. Additionally, further research is needed to determine effective interventional programs to improve the overall quality of life.

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Impact of Preventive Therapy with Nadolol and Topiramate on the Quality Of Life Of Migraine Patients

Cephalalgia ◽

10.1111/j.1468-2982.2007.01367.x ◽

2007 ◽

Vol 27 (8) ◽

pp. 920-928 ◽

Cited By ~ 14

Author(s):

JC Garcia-Monco ◽

N Foncea ◽

A Bilbao ◽

I Ruiz de Velasco ◽

M Gomez-Beldarrain

Keyword(s):

Quality Of Life ◽

Depression Scale ◽

Preventive Therapy ◽

Anxiety And Depression ◽

Physical Domain ◽

Depressive State ◽

Migraine Frequency ◽

Sf 36 ◽

The Impact

Preventive therapy is aimed at reducing migraine frequency, but should also improve the much deteriorated quality of life of the migraneur. We aimed to evaluate the impact of preventive therapy with two widely employed drugs (topiramate and nadolol) on the quality of life of migraine patients. A population of consecutive migraineurs aged ≥16 years, with frequent migraines, was selected prospectively for evaluation at baseline and after 16 weeks of therapy with nadolol or topiramate (40 mg and 100 mg daily, respectively) by generic and specific quality of life questionnaires (SF-36 and MSQOL) and by an anxiety and depression scale (HADS). Preventive therapy resulted in a statistically significant improvement in physical domains of the SF-36, whereas mental domains remained almost unchanged. Despite this improvement, all domains remained below the population norms. The HADS revealed a moderate depressive state at baseline that did not change with therapy. The MSQOL global score also revealed statistically significant improvement. Both drugs were similarly effective, although topiramate was superior on the role physical domain compared with nadolol. Preventive therapy with nadolol and topiramate significantly improves the quality of life of migraineurs, although additional efforts are needed to place them in a nearer-to-normal situation compared with the general population.

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Effects of Support Interventions in Women Hospitalized With Preterm Labor

Clinical Nursing Research ◽

10.1177/1054773817744323 ◽

2017 ◽

Vol 28 (6) ◽

pp. 726-743 ◽

Cited By ~ 2

Author(s):

Mei-Hua Kao ◽

Pi-Feng Hsu ◽

Sheng-Fang Tien ◽

Chie-Pein Chen

Keyword(s):

Quality Of Life ◽

Preterm Labor ◽

Medical Center ◽

Intervention Group ◽

Depression Scale ◽

Anxiety And Depression ◽

Control Group ◽

Clinical Nurses ◽

Anxiety Depression

This study was to examine the effects of support interventions on anxiety, depression, and quality of life in women hospitalized with preterm labor. A randomized, single-blind experimental design was used. Participants were recruited from maternity wards of one medical center in Taiwan. The control group ( n = 103) received routine nursing care, and intervention group ( n = 140) received interventional support during hospitalization. The Beck Anxiety Inventory, Edinburgh Postnatal Depression Scale, and Quality of Life Enjoyment and Satisfaction Questionnaire were used at admission and 2 weeks of hospitalization. For the control group, anxiety and depression scores increased significantly and quality of life decreased 2 weeks after hospitalization. Participants who received 2 weeks of support intervention had significantly lower anxiety and depression scores than controls. Thus, clinical nurses can offer support interventions to improve anxiety and depression for women with preterm labor during hospitalization.

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Psycho-demographic profile in severe asthma and effect of emotional mood disorders and hyperventilation syndrome on quality of life

BMC Psychology ◽

10.1186/s40359-020-00498-y ◽

2021 ◽

Vol 9 (1) ◽

Author(s):

Lucía Dafauce ◽

David Romero ◽

Carlos Carpio ◽

Paula Barga ◽

Santiago Quirce ◽

...

Keyword(s):

Quality Of Life ◽

Severe Asthma ◽

Depression Scale ◽

Anxiety And Depression ◽

Life Questionnaire ◽

Asthma Control Test ◽

Hyperventilation Syndrome ◽

Anxiety Depression ◽

Tas 20

Abstract Background Severe asthma affects a small population but carries a high psychopathological risk. Therefore, the psychodemographic profile of these patients is of interest. A substantial prevalence of anxiety, depression, alexithymia and hyperventilation syndrome in severe asthma is known, but contradictory results have been observed. These factors can also affect patients’ quality of life. For this reasons, our purpose is to evaluate the psychodemographic profile of patients with severe asthma and assess the prevalence of anxiety, depression, alexithymia and hyperventilation syndrome and their impact on the quality of life of patients with severe asthma. Methods A cross-sectional study of 63 patients with severe asthma. Their psychodemographic profile was evaluated using the Hospital Anxiety and Depression Scale (HADS), Toronto Alexithymia Scale (TAS-20), Nijmegen questionnaire and Asthma Control Test (ACT) to determine the state of anxiety and depression, alexithymia, hyperventilation syndrome and control of asthma, respectively. Quality of life was assessed with the Mini Asthma Quality of Life Questionnaire (Mini-AQLQ). Results The mean age was 60 ± 13.6 years. Personal psychopathological histories were found in 65.1% of participants, and 8% reported previous suicidal attempts. The rate of anxiety and/or depression (HADS ≥ 11) was 68.3%. These patients present higher scores on the TAS-20 (p < 0.001) for the level of dyspnea (p = 0.021), and for emotional function (p = 0.017) on the Mini-AQLQ, compared with patients without anxiety or depression. Alexithymia (TAS-20 ≥ 61) was observed in 42.9% of patients; these patients were older (p = 0.037) and had a higher HADS score (p = 0.019) than patients with asthma without alexithymia. On the other hand, patients with hyperventilation syndrome (Nijmegen ≥ 23) scored higher on the HADS (p < 0.05), on the Mini-AQLQ (p = 0.002) and on the TAS-20 (p = 0.044) than the group without hyperventilation syndrome. Quality of life was related to anxiety-depression symptomatology (r = − 0.302; p = 0.016) and alexithymia (r = − 0.264; p = 0.036). Finally, the Mini-AQLQ total score was associated with the Nijmegen questionnaire total score (r = − 0.317; p = 0.011), and the activity limitation domain of the Mini-AQLQ correlated with the ACT total score (r = 0.288; p = 0.022). Conclusions The rate of anxiety, depression, alexithymia and hyperventilation syndrome is high in patients with severe asthma. Each of these factors is associated with a poor quality of life.

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Anxiety and depression intensity and the quality of life of patients with an implanted pacemaker

Journal of Education, Health and Sport ◽

10.12775/jehs.2021.11.06.018 ◽

2021 ◽

Vol 11 (6) ◽

pp. 170-177

Author(s):

Kamil Sikora ◽

Robert Jan Łuczyk ◽

Agnieszka Wawryniuk ◽

Marta Łuczyk ◽

Agnieszka Zwolak

Keyword(s):

Quality Of Life ◽

Standard Deviation ◽

Pacemaker Implantation ◽

Depression Scale ◽

Anxiety Scale ◽

Anxiety And Depression ◽

Average Score ◽

The Impact ◽

Implanted Pacemaker

Introduction. The consequences of anxiety and depression in various forms affect the course of cardiovascular diseases - including patients with an implanted pacemaker. To improve the quality of care for such patients, it is important to understand the scale of the problem, as well as to determine the impact of the above-mentioned symptoms on the patients' quality of life.Aim of research. The aim of the study was to assess the relationship between the quality of life and the anxiety and depression intensity on patients with implanted pacemakers.Material and methods. The study involved 100 patients hospitalized at the SPSK 4 cardiology clinic in Lublin with an implanted pacemaker. The method of diagnostic survey and research tools were used - the WHOQOL - Bref questionnaire to assess the quality of life and the Hospital Anxiety and Depression Scale (HADS-M). The results of the research are summarized in the statistical analysis.Results. The average score obtained by the respondents on the depression scale was 6.05 points with a standard deviation of 4.47. On the anxiety scale, this result was 7.99 points with a standard deviation of 4.54. The results indicating disorders in both scales concern values higher than or equal to 11 points. On the depression scale they were obtained by 16% of the respondents, while on the anxiety scale 26%. The conducted analyses showed a statistically significant relationship between the level of anxiety and depression and the quality of life of the respondents in all domains. The overall declared quality of life of the respondents and the self-esteem of the health condition were the lower, the higher the anxiety and depression severity coefficient in the study group.Conclusions.1. Most of the studied patients with pacemakers do not have high levels of anxiety and depression. 2. The occurrence of anxiety and depression affects the quality of life of respondents after pacemaker implantation in all domains. 3. Patients with high levels of anxiety and depression have a lower assessment of their quality of life and health.

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Pain, Anxiety, Depression, and Quality of Life in Patients with Vulvodynia

Dermatology ◽

10.1159/000503321 ◽

2019 ◽

Vol 236 (3) ◽

pp. 255-261 ◽

Cited By ~ 2

Author(s):

Maria José Tribó ◽

Carla Canal ◽

Josep-E. Baños ◽

Gemma Robleda

Keyword(s):

Quality Of Life ◽

Unknown Origin ◽

Anxiety And Depression ◽

Cross Sectional ◽

Psychiatric Comorbidities ◽

Pain Anxiety ◽

Burning Pain ◽

Anxiety Depression ◽

The Impact

Background/Aims: The term vulvodynia refers to vulvar pain of unknown origin lasting at least 3 months. Psychiatric comorbidities are a common feature and, along with pain, may severely affect patients’ wellbeing. We aimed to determine the characteristics of pain in vulvodynia, to correlate characteristics with symptoms of anxiety and depression, and to analyse the impact of these factors on patients’ quality of life. Methods: This cross-sectional observational study analysed pain, anxiety, and depression and the effects of these factors on quality of life. Pain, anxiety, and depression were assessed using validated tools in 110 women. Results: Statistical analyses found correlations between pain and anxiety and between anxiety and worsened quality of life. Patients often reported stinging, burning, pain, itching, and dyspareunia, pointing to the importance of temporal, localisation, punctate pressure, thermal, tactile sensitivity, and emotional tension characteristics. Most patients had severe pain related to psychiatric comorbidities and decreased quality of life. Conclusion: Using descriptors of pain quality and assessing anxiety and depression might help to define subgroups of patients that may benefit from different therapeutic approaches and thus enable treatments to be tailored to individual patients.

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Anxiety, Depression, and Quality of Life in Turkish Patients with Glaucoma

Psychological Reports ◽

10.2466/pr0.106.2.343-357 ◽

2010 ◽

Vol 106 (2) ◽

pp. 343-357 ◽

Cited By ~ 23

Author(s):

Sevinc Tastan ◽

Emine Iyigun ◽

Atilla Bayer ◽

Cengizhan Acikel

Keyword(s):

Quality Of Life ◽

Psychological Treatment ◽

Care Service ◽

Health Care Service ◽

Depression Scale ◽

Depression Score ◽

Anxiety And Depression ◽

Older Individuals ◽

Anxiety Depression

The purpose was to investigate the relationship between anxiety, depression, and quality of life in patients with glaucoma. This case-control study was carried out with 121 participants with glaucoma ( M age = 64.2, SD = 13.2; 68 women, 76.0% married) and 64 controls. The data were collected by using a data collection form involving questions on patients' specific characteristics, the Hospital Anxiety and Depression Scale, and the National Eye Institute Visual Function Questionnaire. Rate of clinical anxiety was 14.0% and depression 57.0% among the participants with glaucoma. The anxiety risk in women with glaucoma was found to be 7.5 times higher than in men. Risk of depression was 2.94 times higher in unmarried compared to married participants. Anxiety scores were higher in unmarried participants and women. The mean Depression score was statistically significantly higher for unmarried participants. The incidence of depression and anxiety increased with decreasing quality of life scores. Quality of life was associated negatively with anxiety and depression in patients with glaucoma. Evaluating quality of life, anxiety, and depression in older individuals who have glaucoma and examining the risk factors are important to provide earlier health care service and preventive psychological treatment.

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Less Social Support for Patients With COVID-19: Comparison With the Experience of Nurses

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.554435 ◽

2021 ◽

Vol 12 ◽

Author(s):

Zhenyu Li ◽

Jingwu Ge ◽

Jianping Feng ◽

Riyue Jiang ◽

Qin Zhou ◽

...

Keyword(s):

Quality Of Life ◽

Social Support ◽

Predictive Factor ◽

Rating Scale ◽

Anxiety And Depression ◽

Depression Symptoms ◽

The Social ◽

Anxiety Depression ◽

The Impact

Context: Since December 2019, more than 80,000 patients have been diagnosed with coronavirus disease 2019 (COVID-19) in China. Social support status of COVID-19 patients, especially the impact of social support on their psychological status and quality of life, needs to be addressed with increasing concern.Objectives: In this study, we used social support rating scale (SSRS) to investigate the social support in COVID-19 patients and nurses.Methods: The present study included 186 COVID-19 patients at a Wuhan mobile cabin hospital and 234 nurses at a Wuhan COVID-19 control center. Responses to a mobile phone app-based questionnaire about social support, anxiety, depression, and quality of life were recorded and evaluated.Results: COVID-19 patients scored significantly lower than nurses did on the Social Support Rating Scale (SSRS). Among these patients, 33.9% had anxiety symptoms, while 23.7% had depression symptoms. Overall SSRS, subjective social support scores and objective support scores of patients with anxiety were lower than those of patients without anxiety. This result was also found in depression. In addition, all dimensions of social support were positively correlated with quality of life. Interestingly, in all dimensions of social support, subjective support was found to be an independent predictive factor for anxiety, depression, and quality of life, whereas objective support was a predictive factor for quality of life, but not for anxiety and depression via regression analysis.Conclusion: Medical staffs should pay attention to the subjective feelings of patients and make COVID-19 patients feel respected, supported, and understood from the perspective of subjective support, which may greatly benefit patients, alleviate their anxiety and depression, and improve their quality of life.

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Quality of life is decreased in female patients treated for microprolactinoma

Acta Endocrinologica ◽

10.1530/eje-07-0259 ◽

2007 ◽

Vol 157 (2) ◽

pp. 133-139 ◽

Cited By ~ 29

Author(s):

M Kars ◽

A A van der Klaauw ◽

C S Onstein ◽

A M Pereira ◽

J A Romijn

Keyword(s):

Quality Of Life ◽

Short Form ◽

Nottingham Health Profile ◽

Depression Scale ◽

Well Being ◽

Anxiety And Depression ◽

Female Patients ◽

Sf 36 ◽

The Impact

Objective: Most studies on treatment of microprolactinoma have focused on clinical and biochemical outcome rather than on functional and mental well-being. We evaluated this topic in female patients with microprolactinoma, because other pituitary adenomas are associated with decreased quality of life. Design: We conducted a cross-sectional study. Patients and methods: To assess the impact of treatment for microprolactinoma on subjective well-being, quality of life was investigated in 55 female patients (mean age 45 ± 10 years), treated for microprolactinoma in our center, using four validated, health-related questionnaires: Short-Form-36 (SF-36), Nottingham Health Profile (NHP), Multidimensional Fatigue Inventory (MFI-20), and Hospital Anxiety and Depression Scale (HADS). Patient outcomes were compared with those of 183 female controls with equal age distributions. Results: Anxiety and depression scores were increased when compared with controls for all subscales as measured by HADS, and fatigue for all but one subscale as measured by MFI-20. Patients treated for microprolactinoma had worse scores on social functioning, role limitations due to physical problems (SF-36), energy, emotional reaction, and social isolation (NHP) when compared with control subjects. Important independent predictors of quality of life were reproductive status and anxiety and depression scores according to the HADS. Conclusion: Quality of life is impaired in female patients treated for microprolactinoma, especially due to increased anxiety and depression. These increased anxious and depressive feelings might be due to possible effects of hyperprolactinemia on the central nervous system. Failure to recognize this association may adversely affect patient–doctor relationships.

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Anxiety, Depression and Quality of Life Improve After One Month and Three Months of Home Parenteral Nutrition: A Pilot Study in a Canadian Population

Journal of the Canadian Association of Gastroenterology ◽

10.1093/jcag/gwy045 ◽

2018 ◽

Vol 2 (4) ◽

pp. 178-185

Author(s):

Maria Ines Pinto-Sanchez ◽

Shannon Gadowsky ◽

Suzan McKenzie ◽

Michael J Raphael ◽

Anne Childs ◽

...

Keyword(s):

Quality Of Life ◽

Parenteral Nutrition ◽

Depression Scale ◽

Home Parenteral Nutrition ◽

Anxiety And Depression ◽

Underlying Malignancy ◽

Sf 36 ◽

Hospital To Home ◽

Anxiety Depression

Abstract Background Patients receiving home parenteral nutrition (HPN) have a reduced quality of life (QoL), but it is unknown if this is associated with psychiatric comorbidities such as anxiety or depression. Aim The aim of this study was to assess anxiety, depression and QoL in patients transitioning from hospital to HPN. Methods We conducted a prospective study in adult patients receiving parenteral nutrition (PN) during transition from hospital to home. We assessed anxiety and depression (Hospital Anxiety and Depression Scale; HADS), health-related quality of life (HRQoL; SF-36) and health status (EQ-5D) before discharge and again later at one and three months after HPN was started. Results Of the 29 patients, 15 had an underlying malignancy. At baseline, 93% of patients with malignancy had anxiety or depression (HADS A and/or HADS D >7) or both, while of the patients without malignancy, 60% had anxiety, and 40% had depression. Questionnaires were completed by 21 patients at one month and by 15 at three months. Anxiety and depression scores decreased significantly after one month of HPN (mean difference [MD] anxiety: 4.3; 95% CI, 1.2–7.5, P = 0.004; MD depression: 4.0; 95% CI, 1.5–6.5, P = 0.001), and the decrease persisted at three months (MD anxiety: 35; 95% CI, 0.35–6.6, P = 0.02; MD depression: 2.5; 95% CI, 0.06–5.0, P = 0.04). Overall, patients reported an improvement in HRQoL (SF-36) after one month of HPN, and this improvement was maintained at three months in those patients who survived. Conclusion Home parenteral nutrition is associated with improvements in anxiety, depression and HRQoL at one month and three months after discharge from hospital. The improvements in Qol, anxiety and depression seem greater in patients with underlying malignancy.

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