scholarly journals Low Molecular Weight Chitosan from Shrimp Shell Waste using Steam-Explosion Process Under Catalyst of Phosphotungstic Acid

2019 ◽  
Vol 35 (1) ◽  
pp. 193-199
Author(s):  
Dina Sugiyanti ◽  
Sri Anggrahini ◽  
Yudi Pranoto ◽  
Chairil Anwar ◽  
Umar Santoso
Keyword(s):  
Molecular Weight ◽  
Steam Explosion ◽  
Water Solubility ◽  
Phosphotungstic Acid ◽  
Sem Analysis ◽  
Low Molecular Weight ◽  
Explosion Process ◽  
Shrimp Shell ◽  
Low Molecular Weight Chitosan ◽  
Shrimp Shell Waste

The limited solubility of chitosan had limiting its application in any fields. Low molecular weight chitosan (LWCS) potentially produced to improve its solubility and characteristics. Steam explosion process was used to breakdown the intermolecular hydrogen bonding and phosphotungstic acid used as catalyst to attact the glycosidic bond and produce shorter chain. The optimum temperature and phosphotungstic acid concentration on steam explosion process presented highest water solubility at T=160oC and 0.1%, respectively. It didn’t showed any change of functional group on FTIR analysis, no morphological damage by SEM analysis, and reduced the crystallinity. The particle size and molecular weight was reduced from 100 µm to 255 nm and 557 kDa to 4800 Da, respectively. It can be known that LWCS potentially produced with high solubility and fine characteristics through steam explosion process catalyzed by phosphotungstic acid.

scholarly journals Biological Activity of Native and Low Molecular Weight Chitosan obtained by Steam Explosion Process

2018 ◽  
Vol 21 (9) ◽  
pp. 441-447 ◽  
Author(s):  
Dina Sugiyanti ◽  
Purnama Darmadji ◽  
Umar Santoso ◽  
Yudi Pranoto ◽  
Chairil Anwar ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Biological Activity ◽  
Steam Explosion ◽  
Low Molecular Weight ◽  
Explosion Process ◽  
Low Molecular Weight Chitosan

scholarly journals PREPARATION AND CHARACTERIZATION OF LOW MOLECULAR WEIGHT CHITOSAN WITH DIFFERENT DEGREES OF DEACETYLATION BY THE ACID HYDROLYSIS METHOD

2021 ◽  
pp. 153-164
Author(s):  
NAWZAT D. AL-JBOUR ◽  
M. D. H. BEG ◽  
JOLIUS GIMBUN ◽  
A. K. M. MOSHIUL ALAM
Keyword(s):  
Molecular Weight ◽  
Acid Hydrolysis ◽  
Water Solubility ◽  
Skeletal Structure ◽  
Low Molecular Weight ◽  
Molecular Weights ◽  
Hydrolysis Method ◽  
Significant Difference ◽  
Low Molecular Weight Chitosan ◽  
Pharmaceutical Industries

Objective: The objective of this research is to prepare Low Molecular Weight Chitosan (LMWC) by the acid hydrolysis method, using dilute hydrochloric acid (2M). LMWC has superior properties compared to the High Molecular Weight Chitosan (HMWC), especially in terms of water solubility, antibacterial and antifungal properties. These could open new potential applications for LMWC in sectors such as the cosmetics, food, and pharmaceutical industries. Methods: In this work, the acid hydrolysis method was used to produce LMWC with different molecular weights starting from 500 kDa and 93% degree of deacetylations (DDA). The molecular weights of the produced grades were determined by applying Mark-Houwink equation while the %DDA was determined and verified by the use of the 1st derivative UV method and 1HNMR method, respectively. The depolymerization reactions were carried out with different time intervals to produce totally deacetylated LMWC of 30 kDa, 15 kDa, and 7.5 kDa. The LMWC was characterized by FTIR, XRD, and DSC to evaluate the functionality, microstructure and thermal properties. Results: The FTIR spectra revealed that there is no significant difference in the main skeletal structure of the LMWC and HMWC. On the other hand, the XRD and DSC results showed that the LMWC of different molecular weights and degrees of deacetylation are of semi-crystalline structure, similar to the HMWC. Conclusion: The obtained results showed that the used acid hydrolysis procedure can produce LMWC grades of desired specifications, yields, and quality which are suitable for use in different applications.

Preparation and Properties of Oligomeric Sulfonated Chitosan

2012 ◽  
Vol 624 ◽  
pp. 274-278
Author(s):  
Ying Liu ◽  
Chang Ping Wei ◽  
Li Dan Dong
Keyword(s):  
Molecular Weight ◽  
Reaction Temperature ◽  
Water Solubility ◽  
Raw Materials ◽  
Homogeneous System ◽  
Low Molecular Weight ◽  
Equal Proportion ◽  
High Sulfur Content ◽  
Low Molecular Weight Chitosan ◽  
H2o2 Oxidation

In the homogeneous system, the low molecular weight Chitosan is obtained by H2O2 oxidation degradation method. Acetyl Sulface reacted by the mixture of Acetic Anhydride and Concentrated Sulfuric Acid at equal proportion is the reagent. low molecular weight Chitosan being as raw materials, Vulcanized Oligomer Chitosan is sulfonated with good water-solubility and high sulfur content under certain conditions. It has been tested for the influence of the usage of sulfonated reagent, reaction temperature and reaction time on Sulfer content. The best condition for preparation Vulcanized Oligomer Chitosan is 5ml of Acetyl Sulface with the reaction temperature of 25°C and time of 5 Hours. It’s a new potential heparin with around 100 nm particale size tested by spectral analysis and SEM measurements, which could be a new reagent in other fields.

scholarly journals Base-catalysed, one-step mechanochemical conversion of chitin and shrimp shells into low molecular weight chitosan

2017 ◽  
Vol 19 (12) ◽  
pp. 2783-2792 ◽  
Author(s):  
Xi Chen ◽  
Huiying Yang ◽  
Ziyi Zhong ◽  
Ning Yan
Keyword(s):  
Molecular Weight ◽  
Solid State ◽  
Mechanical Milling ◽  
Low Molecular Weight ◽  
Base Catalyst ◽  
Mechanochemical Method ◽  
Shrimp Shells ◽  
Shrimp Shell ◽  
Low Molecular Weight Chitosan ◽  
One Step

A facile, solid-state mechanochemical method was developed for the synthesis of low molecular weight chitosan (LMWC) in one step from chitin and crude shrimp shell powders, in which chitin undergoes simultaneous deacetylation and depolymerisation in the presence of a base catalyst under mechanical milling.

Preparation of low-molecular-weight chitosan by enzymatic hydro-lysis for use in peliculture

2021 ◽  
pp. 31-33
Author(s):  
Элана Игоревна Ковалева ◽  
Марина Алексеевна Фролова ◽  
Алексей Иванович Албулов ◽  
Валерий Петрович Варламов ◽  
Анатолий Константинович Елисеев
Keyword(s):  
Molecular Weight ◽  
Enzymatic Hydrolysis ◽  
Environmental Factors ◽  
Low Molecular Weight ◽  
Technological Parameters ◽  
Low Molecular Weight Chitosan

Хитозан и его производные обладают множеством свойств, которые позволяют применять его в пчеловодстве. Он повышает устойчивость организма пчел к неблагоприятным факторам внешней среды и к возбудителям различных заболеваний. В результате проведенных исследований разработаны технологические параметры получения низкомолекулярного хитозана методом ферментативного гидролиза. Chitosan and its derivatives have many properties that allow them to be used in beekeeping. It increases the resistance of the bee organism to adverse environmental factors and to pathogens of various diseases. As a result of the conducted research, the technological parameters for the production of low-molecular-weight chitosan by enzymatic hydrolysis were developed.

Liposome coated with low molecular weight chitosan and its potential use in ocular drug delivery

2009 ◽  
Vol 379 (1) ◽  
pp. 131-138 ◽  
Author(s):  
Ning Li ◽  
Chunyang Zhuang ◽  
Mi Wang ◽  
Xiyang Sun ◽  
Shufang Nie ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Molecular Weight ◽  
Ocular Drug Delivery ◽  
Low Molecular Weight ◽  
Low Molecular Weight Chitosan ◽  
Potential Use

Searching for synergistic effects of low-molecular weight chitosan derivatives, chitosan and copper nanoparticles for wound healing ointment

2021 ◽  
Vol 12 (3) ◽  
pp. 035016
Author(s):  
Natalya Nikolaevna Glushchenko ◽  
Olga Alexandrovna Bogoslovskaya ◽  
Balzhima Tsyrendorzhievna Shagdarova ◽  
Alla Victorovna Il’ina ◽  
Irina Pavlovna Olkhovskaya ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Wound Healing ◽  
Copper Nanoparticles ◽  
Synergistic Effects ◽  
Low Molecular Weight ◽  
Chitosan Derivatives ◽  
Low Molecular Weight Chitosan
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