scholarly journals Study of Antifungal Activity Using Three Chinese Medicine Herbs

2021 ◽  
Vol 71 (4) ◽  
pp. 322-329
Author(s):  
Anming Zhu ◽  
Shiming Ren ◽  
Xueqi Li ◽  
Xiaoqi Zhao ◽  
Lei Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Antifungal Activity ◽  
Herbal Medicines ◽  
Wood Preservative ◽  
Growth Cycle ◽  
Inhibitory Effect ◽  
Chinese Herbs ◽  
Primary Data ◽  
Chinese Herbal ◽  
Direct Killing

Abstract Chinese medicine herbal extracts are ideal candidates to replace toxic industrial wood preservatives thanks to their antifungal and nontoxic properties. To investigate the antifungal activity of Chinese herbal medicines, in this study, Trametes versicolor fungi were selected as test strains to evaluate the antifungal properties of Fructus Cnidii, Fructus Forsythiae, and Radix Stemonae. The results show that Fructus Cnidii has a strong inhibitory effect against T. versicolor, whereas Fructus Forsythiae and Radix Stemonae have a weak inhibitory effect. The hyphae growth cycle shows that the three studied Chinese herbs disrupt the growth of T. versicolor. Moreover, instead of direct killing, the Chinese herbal medicine demonstrated inhibition ability. Furthermore, the morphological and toxicological evidence shows that Fructus Cnidii affected the expression of proteins or enzymes to achieve the inhibition goal. In sum, this study could provide both primary data and a theoretical foundation for further developing and applying for traditional Chinese medicine as a green type of wood preservative.

Analysis of Chinese herbal formulae recommended for COVID-19 in different schemes in China: A data mining Approach

2020 ◽  
Vol 23 ◽  
Author(s):  
LiWei Yin ◽  
YaCen Gao ◽  
ZiPing Li ◽  
MengYu Wang ◽  
KaiXin Chen
Keyword(s):  
Data Mining ◽  
Early Stage ◽  
Herbal Medicines ◽  
Chinese Herbs ◽  
Recovery Stage ◽  
Prescription Pattern ◽  
Middle Stage ◽  
Chinese Herbal ◽  
Severe Stage ◽  
Herbal Formulae

Background: Novel coronavirus pneumonia (NCP), or coronavirus disease 2019 (COVID-19), is a worldwide health threat that has affected millions of people globally. Traditional Chinese medicine (TCM) has been introduced for the treatment of COVID-19. However, efficacy differs among herbal medicines, and the ideal prescription pattern for TCM herbal formulae for COVID-19 treatment needs to be explored. Therefore, the data mining method has been used in this study to analyze the TCM prescription pattern for COVID-19. Objective: The aim of this study was to analyze the TCM prescription pattern in Regional Schemes in China for COVID-19 in order to provide a new reference for the use of TCM in COVID-19 treatment. Method: By searching the TCM treatment protocols of COVID-19 in 23 Regional Schemes, TCM syndromes and herbal medicines were analyzed by data mining. The Ancient and Modern Medical Case Cloud Platform (V2.1 personal Edition) was used to perform frequency statistics, correlation analysis, and cluster analysis. A total of 82 TCM syndromes and 171 Chinese herbal medicines were found. The course of the disease can be divided into the early stage, middle stage, severe stage, and recovery stage. Results: In the early stage, the focus is primarily on resolving dampness, dispelling cold, and diffusing the lungs. In the middle stage, the treatment priority is clearing heat and resolving toxins, promoting lung function, and relieving asthma. In the severe stage, the focus is on tonifying Qi, restoring Yang, and relieving depletion of Yin and Yang. In the recovery stage, the main treatment is to invigorate the spleen and regulate Qi, tonify Qi, nourish Yin, and clear residual disease evil. There are certain differences between the Regional Schemes and the Nation Schemes, but the core prescription pattern of the former is consistent with the latter. The effectiveness of these 171 Chinese herbs include but are not limited to inhibiting COVID-19, strengthening immune system function, preventing heart failure, acting as antioxidants, oxidative stress inhibitory effects, maintaining organ function, and improving leukocyte survival. Conclusion: This study may help to improve understanding of TCM herbal prescription pattern, practices, reveal the efficacy of combinations of Chinese herbs, and provide new ideas for TCM treatment for COVID-19.

The Indispensable Value of Clinical Trials in the Modernization of Traditional Chinese Medicine: 12 Years' Experience at CUHK and Future Perspectives

2014 ◽  
Vol 42 (03) ◽  
pp. 587-604 ◽  
Author(s):  
Willmann Liang ◽  
David T. Yew ◽  
Kam Lun Hon ◽  
Chun Kwok Wong ◽  
Timothy C. Y. Kwok ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Chinese Medicine ◽  
Herbal Medicines ◽  
Chinese Herbs ◽  
Protective Effects ◽  
Beneficial Effects ◽  
Artery Disease ◽  
The Many

The last decade has seen a wealth of information reporting the beneficial effects of Chinese herbal medicines. While a lot more studies were done using in vitro and in vivo research platforms, much fewer investigations were conducted according to evidence-based requirements in clinical settings. The Institute of Chinese Medicine at the Chinese University of Hong Kong (CUHK) has had the opportunity to collaborate with clinicians over the years to initiate and conduct dozens of clinical trials investigating and verifying the therapeutic values of Chinese herbs in selected disease conditions. Of the many disorders, we chose to focus on those that are known for their difficulties achieving perfect results with conventional treatment methods. Examples include non-healing ulcers, allergic conditions, degenerative diseases and cancer. Protective effects of the herbs in such chronic diseases as coronary artery disease and osteoporosis were also part of our focus. Even in healthy individuals and those recovering from chemotherapy, Chinese herbs could help with the immune system and were studied in our clinical trials as well. This paper aims to highlight the important findings from these clinical studies while at the same time, stressing the indispensable value of clinical trials in modernizing the use of Chinese herbs in present-day medicine.

scholarly journals Application of Spontaneous Photon Emission in the Growth Ages and Varieties Screening of Fresh Chinese Herbal Medicines

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Xiaolei Zhao ◽  
Jingxiang Pang ◽  
Jialei Fu ◽  
Meina Yang ◽  
Eduard Van Wijk ◽  
...  
Keyword(s):  
Photon Emission ◽  
Herbal Medicines ◽  
Chinese Herbs ◽  
Bioactive Constituents ◽  
Curative Effect ◽  
Active Compounds ◽  
Chinese Herbal Medicines ◽  
Chinese Herbal ◽  
Living Organisms ◽  
Natural Medicines

Ultraweak photon emission emitted by all living organisms has been confirmed to be a noninvasive indicator for their physiological and pathological characteristics. In this study, we investigated the characteristics of spontaneous photon emission (SPE) and the contents of specific active compounds of roots and flowers buds of several fresh Chinese herbal medicines (natural medicines) with different growth ages and varieties. The results revealed that the contents of specific active compounds from same species herbs with different growth ages and varieties were significantly different, and this difference could be reflected by their SPE. Because the contents of specific bioactive constituents in Chinese herbs are closely related to their quality and curative effect, the SPE measurement technique may contribute to the quality control of Chinese herbal medicine in the future.

scholarly journals Chinese herbal medicines with beneficial effects

2021 ◽  
Vol 1 (2) ◽  
pp. 79-83
Author(s):  
De-an Guo ◽  
Wenlong Wei ◽  
Changliang Yao ◽  
Jianqing Zhang ◽  
Qirui Bi
Keyword(s):  
Herbal Medicines ◽  
Extreme Environment ◽  
Chinese Herbs ◽  
Exploration And Exploitation ◽  
Chinese Herbal Medicines ◽  
Beneficial Effects ◽  
Medical Needs ◽  
Chinese Herbal ◽  
Potential Applications ◽  
Herbal Species

Abstract Among the vast resources of traditional Chinese medicine (TCM) herbal species, only a handful of Chinese herbs are growing in frigid regions or extreme environment but they have a unique property. The most recognizable TCM herb falling in this category is Panax ginseng, which is widely considered the representative tonic herb with oceans of beneficial effects on human health. In this article, we will introduce several typical Chinese herbal medicines with beneficial effects aiming to arouse broader attention from the scientific community to expand the exploration and exploitation on this for their potential applications to meet the increasingly demanding medical needs.

scholarly journals Stability of Alkaloids during Drying Process and Their Effect on Anticoagulating Activity of Uncariae Ramulus Cum Uncis

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Lu Zou ◽  
Fengyu Lu ◽  
Bing Lin ◽  
Ying Zhou ◽  
Tingting Liu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Constant Temperature ◽  
Herbal Medicines ◽  
Procoagulant Activity ◽  
Drying Process ◽  
Coagulation Time ◽  
Chinese Herbal Medicines ◽  
Chinese Herbal

The drying process of Uncariae Ramulus Cum Uncis (URCU), a kind of traditional Chinese medicine, was studied in a scale dryer in laboratory at 65°C. It was observed that the alkaloids content of URCU firstly showed a tendency of increasing and then decreasing after reaching the peak at the 570th minute in the process of constant temperature drying. Moreover, the coagulation time of rabbit determined by test tubes has been adopted to study the effect imposed by the content of alkaloids on the anticoagulating activity of URCU. In addition, the software of Minitab was also utilized to fit the correlation between the content of alkaloids and the anticoagulating activity of URCU. The results obtained demonstrated that anticoagulant activities were available in both rhynchophylline and isorhynchophylline, among which the latter was the stronger one, while procoagulant activity was shown in corynoxeine. The case study can provide a useful reference for the research on drying other Chinese herbal medicines (CHMs) and further study on URCU.

A permeation cup method for screening packaging materials for fragrance preservation in Chinese medicine

2016 ◽  
Vol 8 (40) ◽  
pp. 7387-7395 ◽  
Author(s):  
Xianghui Li ◽  
Ling Li ◽  
Yunlong Song ◽  
Huiliang Li ◽  
Zhenyu Zhu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Herbal Medicines ◽  
Barrier Properties ◽  
Volatile Components ◽  
Packaging Materials ◽  
Chinese Herbal Medicines ◽  
Plastic Packaging ◽  
Chinese Herbal

Barrier properties of common plastic packaging materials were efficiently evaluated using a permeation cup method with GC-MS, in order to prevent loss of volatile components in typical Chinese herbal medicines.

scholarly journals Promoting Effects on Proliferation and Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells by Four “Kidney-Tonifying” Traditional Chinese Herbs

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Bin Cai ◽  
Ai-guo Zhang ◽  
Xian Zhang ◽  
Wen-jie Ge ◽  
Guo-da Dai ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Chondrogenic Differentiation ◽  
Herbal Medicines ◽  
Chinese Herbs ◽  
Radix Astragali ◽  
Saussurea Involucrata ◽  
Positive Effects ◽  
Chinese Herbal ◽  
Herba Epimedii

Traditional Chinese medicine can promote the proliferation of bone marrow-derived mesenchymal stem cells (BMSCs). We chose four “Kidney-tonifying” Chinese herbal medicines, Radix Astragali, Salvia, Herba Epimedii, and Saussurea Involucrata, to evaluate whether they had positive effects on the proliferation of BMSCs and TGF-β1-induced chondrogenic differentiation of BMSCs. The four Chinese herbal medicines were intragastrically administered to Sprague-Dawley rats, respectively, to prepare drug-containing serums of corresponding Chinese herbs. BMSCs were isolated, cultured, and exposed to culture solution containing 1%, 5%, 10%, and 15% (v/v) Radix Astragali-, Salvia-, Herba Epimedii-, and Saussurea Involucrata-containing serum, respectively. TGF-β1-induced BMSCs were addressed in the same manner. Collagen type II protein was assessed by immunofluorescence methods. To assess whether the drug-containing serums had positive effects on the proliferation of BMSCs and TGF-β1-induced BMSCs, MTT method was assessed. The proliferation of BMSCs was significantly enhanced when exposed to culture solutions containing 1% and 5% Radix Astragali-, 1% and 5% Salvia-, 5% Herba Epimedii-, and 1%, 5%, and 10% Saussurea Involucrata-containing serum. The proliferation of TGF-β1-induced BMSCs was significantly enhanced when exposed to 1%, 5%, and 15% Radix Astragali-, 10% and 15% Salvia-, 5%, and 15% Herba Epimedii-, and 1%, 5%, and 10% Saussurea Involucrata-containing serum.

Treatment of Diabetes Using Traditional Chinese Medicine: Past, Present and Future

2012 ◽  
Vol 40 (05) ◽  
pp. 877-886 ◽  
Author(s):  
Xiao-Lin Tong ◽  
Liu Dong ◽  
Liang Chen ◽  
Zhong Zhen
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Herbal Medicines ◽  
Basic Research ◽  
Holistic Approach ◽  
Medical Problem ◽  
The Past ◽  
Chinese Herbal ◽  
Treatment Of Diabetes ◽  
Tcm Theory

Diabetes is a major medical problem that imperils public health. Over two thousand years ago, Traditional Chinese Medicine (TCM) called diabetes-related symptoms "Xiaoke" disease. In ancient China, TCM and Chinese herbal medicines were used widely in treating Xiaoke and abundant experience has been accumulated. This article discusses the TCM theory on diabetes and its achievements in the prevention and treatment of diabetes in the past. Using Chinese herbal medicine, recent progress in diabetes therapeutics, including data from clinical trials, are presented. Mechanistic studies from basic research are discussed. Yin-yang balance and a holistic approach of TCM may complement diabetes treatment in Western medicine. With continuous efforts, TCM could play a more important role in fighting this disease.

Sign in / Sign up

Export Citation Format

Share Document