scholarly journals Parental death in childhood and pathways to increased mortality across the life course in Stockholm, Sweden: A cohort study

PLoS Medicine ◽  
2021 ◽  
Vol 18 (3) ◽  
pp. e1003549
Author(s):  
Ayako Hiyoshi ◽  
Lisa Berg ◽  
Alessandra Grotta ◽  
Ylva Almquist ◽  
Mikael Rostila
Keyword(s):  
Cohort Study ◽  
Life Course ◽  
Mortality Risk ◽  
Early Adulthood ◽  
Parental Death ◽  
Delinquent Behaviour ◽  
Bereaved Children ◽  
All Cause Mortality ◽  
Behavioural Factors ◽  
The Life Course

Background Previous studies have shown that the experience of parental death during childhood is associated with increased mortality risk. However, few studies have examined potential pathways that may explain these findings. The aim of this study is to examine whether familial and behavioural factors during adolescence and socioeconomic disadvantages in early adulthood mediate the association between loss of a parent at age 0 to 12 and all-cause mortality by the age of 63. Methods and findings A cohort study was conducted using data from the Stockholm Birth Cohort Multigenerational Study for 12,615 children born in 1953, with information covering 1953 to 2016. Familial and behavioural factors at age 13 to 19 included psychiatric and alcohol problems in the surviving parent, receipt of social assistance, and delinquent behaviour in the offspring. Socioeconomic disadvantage in early adulthood included educational attainment, occupational social class, and income at age 27 to 37. We used Cox proportional hazard regression models, combined with a multimediator analysis, to separate direct and indirect effects of parental death on all-cause mortality. Among the 12,582 offspring in the study (men 51%; women 49%), about 3% experienced the death of a parent in childhood. During follow-up from the age of 38 to 63, there were 935 deaths among offspring. Parental death was associated with an elevated risk of mortality after adjusting for demographic and household socioeconomic characteristics at birth (hazard ratio [HR]: 1.52 [95% confidence interval: 1.10 to 2.08, p-value = 0.010]). Delinquent behaviour in adolescence and income during early adulthood were the most influential mediators, and the indirect associations through these variables were HR 1.03 (1.00 to 1.06, 0.029) and HR 1.04 (1.01 to 1.07, 0.029), respectively. After accounting for these indirect paths, the direct path was attenuated to HR 1.35 (0.98 to 1.85, 0.066). The limitations of the study include that the associations may be partly due to genetic, social, and behavioural residual confounding, that statistical power was low in some of the subgroup analyses, and that there might be other relevant paths that were not investigated in the present study. Conclusions Our findings from this cohort study suggest that childhood parental death is associated with increased mortality and that the association was mediated through a chain of disadvantages over the life course including delinquency in adolescence and lower income during early adulthood. Professionals working with bereaved children should take the higher mortality risk in bereaved offspring into account and consider its lifelong consequences. When planning and providing support to bereaved children, it may be particularly important to be aware of their increased susceptibility to delinquency and socioeconomic vulnerability that eventually lead to higher mortality.

scholarly journals Childhood bereavement and adult mortality: A 65-year follow-up of the Stockholm birth cohort

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
A Hiyoshi ◽  
L Berg ◽  
A Grotta ◽  
Y Almquist ◽  
M Rostila
Keyword(s):  
Life Course ◽  
Birth Cohort ◽  
Mortality Risk ◽  
Excess Mortality ◽  
Parental Loss ◽  
Health Consequences ◽  
Childhood Bereavement ◽  
Bereaved Children ◽  
Death Of A Parent ◽  
The Life Course

Abstract About 3% of children in Sweden, 4-5% in the UK, and 5% in the US experience the death of a parent during childhood. The event is highly unexpected and stressful and could have long-term social and health consequences across the life course. To alleviate grief, bereaved children may engage in health-damaging behaviours such as smoking, alcohol or drug abuse, violence, delinquency and risky sexual behaviour. Few studies have been able to study health consequences by childhood parental loss and mechanisms explaining associations across the life course. Using the Stockholm Birth Cohort Study (SBC), including all children born in 1953 in the metropolitan Stockholm area, we examined whether childhood bereavement is associated with all-cause mortality until age 63 and whether various pathways (e.g. economic, behavioral and social circumstances) account for the association. 15,117 individuals were followed between 1953 and 2018 using survey data and national registry data. We used Cox proportional hazard regression and mediation analysis for survival analysis to decompose direct and indirect effects. The death of a parent was associated with 40 to 50% elevated risk of mortality in offspring, and the association was mediated through delinquent behaviour in adolescence and income in adulthood especially for male offspring. Our findings suggest that parental loss has a life long impact on the mortality risk of bereaved children and that interventions targeting delinquency and socio-economic circumstances in bereaved children could be successful in reducing their excess mortality risk. Key messages Bereavement in childhood has a life-long impact on health. Interventions targeting delinquency and socio-economic circumstances could be successful in reducing the excess mortality risk.

Changes in incisor relationship over the life course - Findings from a cohort study

2021 ◽  
pp. 103919
Author(s):  
Olliver SJ ◽  
Broadbent JM ◽  
Sabarinath Prasad ◽  
Celene Cai ◽  
W. Murray Thomson ◽  
...  
Keyword(s):  
Cohort Study ◽  
Life Course ◽  
The Life Course

scholarly journals Socio-economic position at four time points across the life course and all-cause mortality: updated results from the Uppsala Birth Cohort Multigenerational Study

2020 ◽  
Vol 11 (1) ◽  
pp. 27-54
Author(s):  
Amy Heshmati ◽  
Gita D Mishra ◽  
Anna Goodman ◽  
Ilona Koupil
Keyword(s):  
Life Course ◽  
Birth Cohort ◽  
Later Life ◽  
University Hospital ◽  
Sensitive Period ◽  
Saturated Model ◽  
All Cause Mortality ◽  
Economic Position ◽  
The Life Course ◽  
Multigenerational Study

Socio-economic position (SEP) is associated with all-cause mortality across all stages of the life course; however, it is valuable to distinguish at what time periods SEP has the most influence on mortality. Our aim was to investigate whether the effect of SEP on all-cause mortality accumulates over the life course or if some periods of the life course are more important. Our study population were from the Uppsala Birth Cohort Multigenerational Study, born 1915–29 at Uppsala University Hospital, Sweden. We followed 3,951 men and 3,601 women who had SEP at birth available, during childhood (at age ten), in adulthood (ages 30–45) and in later life (ages 50–65) from 15 September 1980 until emigration, death or until 31 December 2010. We compared a set of nested Cox proportional regression models, each corresponding to a specific life course model (critical, sensitive and accumulation models), to a fully saturated model, to ascertain which model best describes the relationship between SEP and mortality. Analyses were stratified by gender. For both men and women the effect of SEP across the life course on all-cause mortality is best described by the sensitive period model, whereby being advantaged in later life (ages 50–65 years) provides the largest protective effect. However, the linear accumulation model also provided a good fit of the data for women suggesting that improvements in SEP at any stage of the life course corresponds to a decrease in all-cause mortality.

Youth Violence in Germany

2018 ◽  
Vol 43 (3) ◽  
pp. 325-344 ◽  
Author(s):  
Anke Erdmann ◽  
Jost Reinecke
Keyword(s):  
Life Course ◽  
Youth Violence ◽  
Mutual Influence ◽  
Early Adulthood ◽  
Theory Development ◽  
Self Report ◽  
Latent Growth ◽  
German Research Foundation ◽  
Parallel Processes ◽  
The Life Course

The victim–offender overlap is currently under discussion in criminology. However, the connection between victimization and offending over the life course still requires further investigation. The present study examines whether the victim–offender overlap is invariant during the transition from adolescence to early adulthood using seven consecutive waves of the German Research Foundation–funded self-report study “Crime in the Modern City,” which contain information about German students from the age of 14 to 20 years. The results indicate that the nature as well as the strength of the overlap changes over the period from adolescence to early adulthood. The introduced measurement of the relative victim–offender overlap indicates that with growing up, fewer victims are also offenders whereas the amount of offenders that are also victims remains stable. Longitudinal analyses based on latent growth and cross-lagged panel models further point out that the developments of victimization and offending are highly parallel processes that evince similar stability and mutual influence over the phase of youth and adolescence. However, the association between both weakens over age. In conclusion, our results suggest variance in the victim–offender overlap over the life course. This justifies the demand for further research and theory development on this criminological phenomenon.

scholarly journals Do childhood socioeconomic circumstances moderate the association between childhood cognitive ability and all-cause mortality across the life course? Prospective observational study of the 36-day sample of the Scottish Mental Survey 1947

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e037847
Author(s):  
Matthew Henry Iveson ◽  
Drew Altschul ◽  
Ian Deary
Keyword(s):  
Social Class ◽  
Cognitive Ability ◽  
Mortality Risk ◽  
Interaction Effect ◽  
Model Fit ◽  
All Cause Mortality ◽  
Childhood Cognitive Ability ◽  
Iq Scores ◽  
The Life Course ◽  
Moderating Role

BackgroundThere is growing evidence that higher childhood cognitive ability predicts lower all-cause mortality risk across the life course. Whereas this association does not appear to be mediated by childhood socioeconomic circumstances, it is unclear whether socioeconomic circumstances moderate this association.MethodsThe moderating role of childhood socioeconomic circumstances was assessed in 5318 members of the 36-day sample of the Scottish Mental Survey 1947. Univariate, sex-adjusted and age-adjusted, and mutually adjusted Cox models predicting all-cause mortality risk up to age 79 years were created using childhood IQ scores and childhood social class as predictors. Moderation was assessed by adding an interaction term between IQ scores and social class and comparing model fit.ResultsAn SD advantage in childhood IQ scores (HR=0.83, 95% CI 0.79 to 0.86, p<0.001) and a single-class advantage in childhood social class (HR=0.92, 95% CI 0.88 to 0.97, p<0.001) independently predicted lower mortality risk. Adding the IQ–social class interaction effect did not improve model fit (χ2Δ=1.36, p=0.24), and the interaction effect did not predict mortality risk (HR=1.03, 95% CI 0.98 to 1.07, p=0.25).ConclusionsThe present study demonstrated that the association between higher childhood cognitive ability and lower all-cause mortality risk is not conditional on childhood social class. Whereas other measures of socioeconomic circumstances may play a moderating role, these findings suggest that the benefits of higher childhood cognitive ability for longevity apply regardless of the material socioeconomic circumstances experienced in childhood.

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