scholarly journals Maternal vitamin D insufficiency and risk of adverse pregnancy and birth outcomes: A systematic review and meta-analysis of longitudinal studies

PLoS ONE ◽  
2017 ◽  
Vol 12 (3) ◽  
pp. e0173605 ◽  
Author(s):  
A. Kofi Amegah ◽  
Moses K. Klevor ◽  
Carol L. Wagner
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Longitudinal Studies ◽  
Birth Outcomes ◽  
Meta Analysis ◽  
Vitamin D Insufficiency ◽  
Maternal Vitamin ◽  
Pregnancy And Birth Outcomes ◽  
Adverse Pregnancy ◽  
Pregnancy And Birth

scholarly journals Maternal dietary patterns and risk of adverse pregnancy (hypertensive disorders of pregnancy and gestational diabetes mellitus) and birth (preterm birth and low birth weight) outcomes: a systematic review and meta-analysis

2018 ◽  
Vol 22 (3) ◽  
pp. 506-520 ◽  
Author(s):  
Kelemu Tilahun Kibret ◽  
Catherine Chojenta ◽  
Ellie Gresham ◽  
Teketo K Tegegne ◽  
Deborah Loxton
Keyword(s):  
Diabetes Mellitus ◽  
Birth Outcomes ◽  
Dietary Patterns ◽  
Meta Analysis ◽  
Whole Grains ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Pregnancy And Birth Outcomes ◽  
Adverse Pregnancy ◽  
Pregnancy And Birth

AbstractObjectiveEpidemiological studies have indicated that dietary patterns during pregnancy are associated with adverse pregnancy and birth outcomes such as hypertensive disorders of pregnancy (HDP), gestational diabetes mellitus (GDM), preterm birth (PTB) and low birth weight (LBW). However, the results of these studies are varied and inconsistent. The present study aimed to assess the association between dietary patterns and the risk of adverse pregnancy and birth outcomes.DesignSystematic review and meta-analysis. Seven databases were searched for articles. Two reviewers performed the study selection and data extraction. A random-effects model was used to estimate pooled effect sizes of eligible studies.SettingStudies conducted all over the world were incorporated.SubjectsThe review focused on pregnant women.ResultsA total of twenty-one studies were identified. Adherence to a healthy dietary pattern (intake of vegetables, fruits, legumes, whole grains) was significantly associated with lower odds (OR; 95 % CI) of pre-eclampsia (0·78; 0·70, 0·86; I2=39·0 %, P=0·178), GDM (0·78; 0·56, 0·99; I2=68·6 %, P=0·013) and PTB (0·75; 0·57, 0·93; I2=89·6 %, P=0·0001).ConclusionsOur review suggests that dietary patterns with a higher intake of fruits, vegetables, legumes, whole grains and fish are associated with a decreased likelihood of adverse pregnancy and birth outcomes. Further research should be conducted in low-income countries to understand the impact of limited resources on dietary intake and adverse pregnancy and birth outcomes.

scholarly journals A Review of the Potential Benefits of Increasing Vitamin D Status in Mongolian Adults through Food Fortification and Vitamin D Supplementation

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2452 ◽  
Author(s):  
William B. Grant ◽  
Barbara J. Boucher
Keyword(s):  
Vitamin D ◽  
Birth Outcomes ◽  
Mortality Rates ◽  
Malignant Neoplasms ◽  
Supplement Use ◽  
Incidence And Mortality ◽  
Pregnancy And Birth Outcomes ◽  
Adverse Pregnancy ◽  
Tract Infections ◽  
Pregnancy And Birth

Serum 25-hydroxyvitamin D (25(OH)D) concentrations are low in Mongolia, averaging 22 ng/mL in summer and only 8 ng/mL in winter. Mongolians have high incidence and/or prevalence of several diseases linked to low 25(OH)D concentrations, including ischemic heart disease, malignant neoplasms, cirrhosis of the liver, ischemic stroke, lower respiratory tract infections, preterm birth complications, and diabetes mellitus. Fortifying regularly consumed foods such as flour, milk, and edible oils with vitamin D3 could raise 25(OH)D concentrations by about 10 ng/mL. However, to achieve 25(OH)D concentrations of 30–40 ng/mL in adults, vitamin D intakes of 1000 to 4000 IU/day would be required, making personal supplement use necessary. On the basis of prospective observational studies and clinical trials of disease incidence or known mortality rates and adverse pregnancy and birth outcomes, raising mean serum 25(OH)D concentrations to 40 ng/mL would likely reduce incidence and mortality rates for those and other diseases, reduce the rate of adverse pregnancy and birth outcomes, and increase mean life expectancy by one year or more.

Association between maternal vitamin D levels and risk of adverse pregnancy outcomes: a systematic review and dose–response meta-analysis

2021 ◽  
Author(s):  
Rui Zhao ◽  
Leilei Zhou ◽  
Shanshan Wang ◽  
Guoping Xiong ◽  
Liping Hao
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Dose Response ◽  
Pregnancy Outcomes ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Adverse Pregnancy Outcomes ◽  
Maternal Vitamin ◽  
Vitamin D Levels ◽  
Adverse Pregnancy

Epidemiological studies have investigated the associations between vitamin D and the risk of adverse pregnancy outcomes; however, the results are conflicting and dose–response relationships remain to be confirmed.

Adverse pregnancy and birth outcomes by infertility diagnoses with and without ART treatment

2014 ◽  
Vol 102 (3) ◽  
pp. e336
Author(s):  
J.E. Stern ◽  
B. Luke ◽  
M. Tobias ◽  
M.D. Hornstein ◽  
H. Diop
Keyword(s):  
Birth Outcomes ◽  
Pregnancy And Birth Outcomes ◽  
Adverse Pregnancy ◽  
Pregnancy And Birth

scholarly journals Maternal Vitamin D Status and Risk of Gestational Diabetes: a Meta-Analysis

2018 ◽  
Vol 45 (1) ◽  
pp. 291-300 ◽  
Author(s):  
Lingmin Hu ◽  
Yue Zhang ◽  
Xing Wang ◽  
Lianghui You ◽  
Pengfei Xu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Gestational Diabetes ◽  
Observational Studies ◽  
Meta Analysis ◽  
Vitamin D Insufficiency ◽  
Significant Heterogeneity ◽  
Vitamin D Status ◽  
Maternal Vitamin ◽  
Increased Risk ◽  
Maternal Vitamin D Status

Background/Aims: Whether maternal vitamin D deficiency is associated with gestational diabetes remains controversial. This meta-analysis aimed to systematically evaluate published evidence on the association between maternal vitamin D status and the risk of gestational diabetes. Methods: We retrieved relevant articles from the PubMed, Medline and Embase databases up to May 2017 for observational studies investigating the association between vitamin D status and the risk of gestational diabetes. Odds ratios (OR) or risk ratios (RR) from individual studies were pooled using the fixed and random effect models. Results: The meta-analysis of 29 observational studies included 28,982 participants, of which 4,634 were diagnosed with gestational diabetes, and showed that maternal vitamin D insufficiency was associated with a significantly increased risk of gestational diabetes by 39% (pooled OR = 1.39, 95%CI = 1.20-1.60) with moderate heterogeneity (I2 = 50.2%; P = 0.001). Moreover, the 25(OH)D level was significantly lower in gestational diabetes cases than in controls with a pooled effect of -4.79 nmol/L (95% CI = -6.43, -3.15). Significant heterogeneity was also detected (I2 = 65.0%, P < 0.001). Further subgroup analysis indicated that this association was also evident in most subpopulations. Conclusion: This meta-analysis indicated a significant association between vitamin D insufficiency and increased risk of gestational diabetes. Further well-designed large-scale clinical trials are essential to verify this association.

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