scholarly journals Marmoset angiography just by percutaneous puncture of the caudal ventral artery

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250576
Author(s):  
Hiroki Ohta ◽  
Teppei Komatsu ◽  
Kanako Muta ◽  
Makoto Koizumi ◽  
Yasuyuki Iguchi ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Therapeutic Intervention ◽  
Animal Experiments ◽  
Multiple Organ ◽  
Invasive Treatment ◽  
Percutaneous Puncture ◽  
Innovative Methods ◽  
A New Technique ◽  
Arterial Damage ◽  
First Time

Surgery in humans is continuously evolving and promoted minimally invasive treatment. On the other hand, despite the importance of the 3Rs principles for experimental animals is well documented, no reports describe specific methodologies for implementing "refinement" in practice. Here, we describe a new technique, the "Ohta Method" for caudal arthrocentesis in the pursuit of the 3Rs for animal experiments and the development of innovative methods for investigating systemic organ arteries through minimally invasive procedures. This procedure requires only a percutaneous puncture of the caudal artery without any injury to the limb or body trunk. In addition, it does not cut down the artery, making hemostasis easier and recovering arterial damage easier. We will show multiple organ artery angiographies in marmoset for the first time in the world. The principle described in this paper could also be applied to many other small animals, such as rats. Moreover, using this method, multiple doses of the drug or cells can be administered to the target organ at the time of therapeutic intervention, thereby enabling the establishment of more sophisticated and complex therapeutic intervention studies as translational research.

scholarly journals Minimally invasive treatment of ureterovaginal fistula: A review and report of a new technique

2012 ◽  
Vol 10 (4) ◽  
pp. 414-417 ◽  
Author(s):  
Khalid Al Otaibi ◽  
Alaa-Eldin Barakat ◽  
Hamed El Darawany ◽  
Abulhasan Sheikh ◽  
Kamel Fadaak ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Minimally Invasive Treatment ◽  
New Technique ◽  
Ureterovaginal Fistula ◽  
Invasive Treatment ◽  
A New Technique

scholarly journals Infected Pancreatic Pseudocysts: Surgical Treatment

2019 ◽  
Vol 9 (1) ◽  
pp. 18-25
Author(s):  
I. A. Kryvoruchko ◽  
N. N. Goncharova
Keyword(s):  
Minimally Invasive ◽  
Treatment Options ◽  
Disaster Medicine ◽  
Multiple Organ ◽  
Pancreatic Pseudocysts ◽  
Surgical Trauma ◽  
Type I ◽  
Invasive Treatment ◽  
Tailored Treatment ◽  
Treatment Techniques

Introduction. The incidence of pancreatic pseudocysts (PPC) amounts to 0.5–1 per 100,000 adults per year. In all the pancreatic disorders the incidence of PPC amounts to 1.6-4.5%. Designing an individually tailored treatment programme using minimally invasive techniques to ensure the longest lasting treatment effect combined with the reduction of surgical trauma is an important issue of today’s surgery.Materials and methods. This paper presents a retrospective analysis of surgeries performed on 101 patients with infected PPC treated in the period from 2000 to 2015 at surgical wards of the Centre for Emergency and Disaster Medicine of the Regional Teaching Hospital, Kharkiv, Ukraine and the Department of Pancreatic and Bile Duct Surgery of A. A. Shalimov National Institute of Surgery and Transplantology, Kyiv, Ukraine. Of these, 74 patients (73.3%) were male and 27 (26.7%) — female, aged 21 to 79, average age of patients was 43.3±1.2 years.Results. Percutaneous drainage was administered to patients with type I infected PPC with the onset of multiple organ failure in order to make the wait-and-see strategy possible and to alleviate the patient’s general condition and improve the course of sepsis. For patients with type II and III infected PPC percutaneous punctures were the final stage of treatment in 80% of cases. Whether radical surgical procedures were performed depended on the severity of the patient’s condition, degree of pancreatic necrosis or chronic pancreatitis spread, PC localisation, duct system condition and complications involving neighbouring organs.Conclusion. When treating patients with PPC one has to use an individually tailored treatment strategy based on state of the art minimally invasive treatment techniques. When treating infected PPC both minimally invasive and traditional open access procedures have to be considered as mutually complementing, presenting a broad range of diagnostic and treatment options.

scholarly journals Laser interstitial thermotherapy (LITT) for the treatment of tumors of the brain and spine: a brief review

2021 ◽  
Vol 151 (3) ◽  
pp. 429-442
Author(s):  
Clark Chen ◽  
Ian Lee ◽  
Claudio Tatsui ◽  
Theresa Elder ◽  
Andrew E. Sloan
Keyword(s):  
Brain Tumors ◽  
Minimally Invasive ◽  
Radiation Necrosis ◽  
Spinal Metastasis ◽  
Clinical Approach ◽  
Invasive Treatment ◽  
Primary Indication ◽  
Interstitial Thermotherapy ◽  
The Brain

Abstract Introduction Laser Interstitial Thermotherapy (LITT; also known as Stereotactic Laser Ablation or SLA), is a minimally invasive treatment modality that has recently gained prominence in the treatment of malignant primary and metastatic brain tumors and radiation necrosis and studies for treatment of spinal metastasis has recently been reported. Methods Here we provide a brief literature review of the various contemporary uses for LITT and their reported outcomes. Results Historically, the primary indication for LITT has been for the treatment of recurrent glioblastoma (GBM). However, indications have continued to expand and now include gliomas of different grades, brain metastasis (BM), radiation necrosis (RN), other types of brain tumors as well as spine metastasis. LITT is emerging as a safe, reliable, minimally invasive clinical approach, particularly for deep seated, focal malignant brain tumors and radiation necrosis. The role of LITT for treatment of other types of tumors of the brain and for spine tumors appears to be evolving at a small number of centers. While the technology appears to be safe and increasingly utilized, there have been few prospective clinical trials and most published studies combine different pathologies in the same report. Conclusion Well-designed prospective trials will be required to firmly establish the role of LITT in the treatment of lesions of the brain and spine.

scholarly journals EAU, AUA and NICE Guidelines on Surgical and Minimally Invasive Treatment of Benign Prostate Hyperplasia: A Critical Appraisal of the Guidelines Using the AGREE-II Tool

2021 ◽  
pp. 1-10
Author(s):  
Dmitry Enikeev ◽  
Vincent Misrai ◽  
Enrique Rijo ◽  
Roman Sukhanov ◽  
Denis Chinenov ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Treatment Options ◽  
Stakeholder Involvement ◽  
Minimally Invasive Treatment ◽  
Invasive Treatment ◽  
Agree Ii ◽  
Prostate Hyperplasia ◽  
Assessment Score ◽  
Nice Guideline ◽  
Agree Ii Tool

<b><i>Objective:</i></b> To critically appraise the methodological rigour of the clinical practice guidelines (CPGs) vis-à-vis BPH surgery as used by specialist research associations in the US, Europe and UK, and to compare whether the guidelines cover all or only some of the available treatments. <b><i>Methods:</i></b> The current guidelines issued by the EUA, AUA and NICE associations have been analyzed by 4 appraisers using the AGREE-II instrument. We also compared the recommendations given in the guidelines for surgical and minimally invasive treatment to find out which of these CPGs include most of the available treatment options. <b><i>Results:</i></b> According to the AGREE II tool, the median scores of domains were: domain 1 scope and purpose 66.7%, domain 2 stakeholder involvement 50.0%, domain 3 rigor of development 65.1%, domain 4 clarity of presentation 80.6%, domain 5 applicability 33.3%, domain 6 editorial independence 72.9%. The overall assessment according to AGREE II is 83.3%. The NICE guideline scored highest on 5 out of 6 domains and the highest overall assessment score (91.6%). The EAU guideline scored lowest on 4 out of 6 domains and has the lowest overall assessment score (79.1%). <b><i>Conclusions:</i></b> The analyzed CPGs comprehensively highlight the minimally invasive and surgical treatment options for BPH. According to the AGREE II tool, the domains for clarity of presentation and editorial independence received the highest scores. The stakeholder involvement and applicability domains were ranked as the lowest. Improving the CPG in these domains may help to improve the clinical utility and applicability of CPGs.

Therapy and regeneration-combined bone cements for minimally invasive treatment of neoplastic bone defects

2021 ◽  
Author(s):  
Yu Qu ◽  
Hui Zhuang ◽  
Meng Zhang ◽  
Yufeng Wang ◽  
Dong Zhai ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Minimally Invasive ◽  
Tumor Cells ◽  
Bone Tumor ◽  
Tumor Resection ◽  
Bone Defects ◽  
Bone Cements ◽  
Invasive Treatment ◽  
Calcium Phosphate Cements ◽  
Bone Tumor Resection

Although calcium phosphate cements (CPC) have been clinically used to repair bone defects caused by bone tumor resection, traditional CPC cannot kill the remaining tumor cells after surgery and prevent...

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