Nurses’ and teachers’ perceived barriers and facilitators to the uptake of the Human Papilloma Virus (HPV) vaccination program in Iquitos, Peru: A qualitative study

Globally, over 300,000 women die of cervical cancer annually. Given that human papillomavirus vaccines are highly effective in the primary prevention of cervical cancer, it is important to explore the barriers and facilitators to vaccination uptake in areas where the burden of disease remains high. This study, informed by the socio-ecological model, aimed to qualitatively explore vaccination uptake via in-depth interviews with eleven nurses and ten teachers involved in vaccine delivery in Iquitos, Peru. The results highlighted that vaccine uptake was influenced by multiple factors including individuals’ knowledge and attitudes, community beliefs, geography, and policy level variables. Findings suggested that professionals were informed and supportive of the HPV vaccination program but perceived that parents were uninformed about the vaccine. There is a need for community education programs, for a revision of the process of obtaining parental consent, for improved communication between professionals and for involvement of grassroots staff in policy making.

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Barriers and Facilitators of Human Papillomavirus (HPV) Vaccination During the Implementation of the School-Based HPV Vaccine Program in Manizales, Colombia

Journal of Global Oncology ◽

10.1200/jgo.18.11000 ◽

2018 ◽

Vol 4 (Supplement 1) ◽

pp. 18s-18s

Author(s):

Verónica Cordoba ◽

Olga Lucía Tovar-Aguirre ◽

Sandra Franco ◽

María del Pilar Escobar ◽

Nelson Enrique Arias ◽

...

Keyword(s):

Cervical Cancer ◽

Human Papillomavirus ◽

Hpv Vaccine ◽

Pap Smear ◽

Hpv Vaccination ◽

Barriers And Facilitators ◽

Vaccine Uptake ◽

Socioeconomic Level ◽

Vaccination Rates ◽

School Based

Abstract 43 Purpose Colombia implemented a school-based human papillomavirus (HPV) vaccination program that consisted of a three-dose series in girls age 9 years in 2012. In 2014, the program included girls up to the last grade of high school, and the second and third doses were scheduled at 6 and 60 months. After a mass psychogenic response after vaccination that occurred from May to October 2014 in Carmen de Bolivar, vaccination rates dropped from 80% in 2012 and 2013 to 18% in 2014. The aim of the current study was to identify barriers and facilitators of HPV vaccine uptake in Colombia. Methods To develop quantitative instruments for a population-based survey, we conducted 19 qualitative interviews and 18 focus groups between September 2016 and February 2017. Participants were girls who were eligible to receive vaccination between 2012 and 2014 and their parents or legal representatives. Results Forty-nine girls who were selected from six schools of low (n = 2), medium (n = 2), and high (n = 2) socioeconomic level and 58 of their parents participated in the study. Eighty-one percent (40 of 49) of girls were age 12 to 15 years at the time of interview. No girls from schools of a low socioeconomic level and only two of 20 of their parents knew the etiology of cervical cancer. Pap smear cytology and condom use were the methods of cervical cancer prevention that were most often mentioned by parents. Only vaccinated girls from schools of a high socioeconomic level considered the HPV vaccine to be a good prevention alternative. Facilitators in adults were the desire to prevent disease in general and HPV. For both girls and their parents, listening to positive information about the vaccine facilitated vaccine uptake. Negative media information about the effects of the vaccine from the 2014 psychogenic event was the main barrier for vaccine uptake or series completion. Fifty-seven percent of girls and 30% of parents mentioned that, at the time of vaccination, information about the HPV vaccine was received mainly through government massive media campaigns, whereas approxiamtely one half of both parents and girls did not receive information from schools or health care services. Conclusion Our results suggest that improving HPV vaccination rates in Colombia will require a comprehensive education program, including mass media information about the HPV vaccine. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST No COIs from the authors.

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Facilitators and Barriers of Cervical Cancer Screening and Human Papilloma Virus Vaccination Among Somali Refugee Women in the United States: A Qualitative Analysis

Journal of Transcultural Nursing ◽

10.1177/1043659618796909 ◽

2018 ◽

Vol 30 (1) ◽

pp. 55-63 ◽

Cited By ~ 2

Author(s):

Elizabeth M. Allen ◽

Hee Yun Lee ◽

Rebekah Pratt ◽

Houa Vang ◽

Jay R. Desai ◽

...

Keyword(s):

Cervical Cancer ◽

Cancer Screening ◽

Human Papilloma Virus ◽

Cervical Cancer Screening ◽

Hpv Vaccination ◽

Vaccine Uptake ◽

Papilloma Virus ◽

Refugee Women ◽

Facilitators And Barriers ◽

Somali Refugee

Introduction: Eastern Africa has the highest rates of cervical cancer incidence (42.7 per 100,000) and mortality (27.6 per 100,000), substantially higher than worldwide incidence (14.0 per 100,000) and mortality (6.8 per 100,000). The purpose of this study was to explore facilitators and barriers to cervical cancer screening and human papilloma virus (HPV) vaccination among Somali refugee women and their children. Method: Focus group discussions were conducted in August of 2016. Investigators performed systematic, comparative, and thematic data analyses. Results: The 31 Somali refugee participants ranged from 23 to 64 years old. Four major themes emerged: (1) knowledge, (2) facilitators, (3) decision making, and (4) views on intervention strategies. Doctor recommendation and family support were important facilitators. Community education was the most popular strategy in promoting screening and vaccine uptake. Discussion: Multilevel targeted interventions should increase knowledge and include family members to increase cervical cancer screening and HPV vaccination uptake in the Somali community.

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HPV VACCINE AND CERVICAL CANCER

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2011.3.15 ◽

2011 ◽

pp. 108-115

Author(s):

Vu Quoc Huy Nguyen

Keyword(s):

Cervical Cancer ◽

Relative Risk ◽

Hpv Vaccine ◽

Hpv Vaccination ◽

Preventive Strategy ◽

Protective Effects ◽

Papilloma Virus ◽

Vaccine Trials ◽

Close Relationship ◽

The Relationship

Persistent infection with high-risk Human Papilloma Virus (HPV) has been identified as the causal factor of cervical cancer, with relative risk up to 300-400 folds. This very close relationship leads to the preventive strategy of vaccination against HPV infections and HPV-related lesions. The article describes molecular and immunologic characteristics of HPV, currently available HPV vaccines and its protective effects; the relationship between HPV vaccination and cervical cancer screening, and an introduction to therapeutic HPV vaccine trials.

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Prostate cancer and the human papilloma virus: causative association, role of vaccines, and the impact of the COVID-19 pandemic

Prostate Cancer and Prostatic Diseases ◽

10.1038/s41391-021-00404-6 ◽

2021 ◽

Author(s):

Naomi Morka ◽

Joseph M. Norris ◽

Mark Emberton ◽

Daniel Kelly

Keyword(s):

Prostate Cancer ◽

Human Papilloma Virus ◽

Hpv Vaccination ◽

Significant Proportion ◽

Vaccine Uptake ◽

Papilloma Virus ◽

Vaccination Campaigns ◽

The Impact ◽

Hpv Vaccine Uptake

AbstractProstate cancer affects a significant proportion of men worldwide. Evidence from genetic and clinical studies suggests that there may be a causal association between prostate cancer and the human papilloma virus (HPV). As HPV is a vaccine-preventable pathogen, the possibility of a role in prostate cancer causation may reinforce the importance of effective HPV vaccination campaigns. This is of particular relevance in light of the COVID-19 pandemic, which may have considerable effects on HPV vaccine uptake and distribution.

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Factors related to vaccine uptake by young adult women in the catch-up phase of the National HPV Vaccination Program in Australia: Results from an observational study

Vaccine ◽

10.1016/j.vaccine.2015.01.024 ◽

2015 ◽

Vol 33 (20) ◽

pp. 2387-2394 ◽

Cited By ~ 11

Author(s):

Karen Canfell ◽

Sam Egger ◽

Louiza S. Velentzis ◽

Jessica Darlington Brown ◽

Dianne L. O’Connell ◽

...

Keyword(s):

Young Adult ◽

Observational Study ◽

Hpv Vaccination ◽

Vaccine Uptake ◽

Vaccination Program ◽

Adult Women ◽

Young Adult Women ◽

Catch Up

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COVID-19 vaccine brand hesitancy and other challenges to vaccination in the Philippines

PLOS Global Public Health ◽

10.1371/journal.pgph.0000165 ◽

2022 ◽

Vol 2 (1) ◽

pp. e0000165

Author(s):

Arianna Maever L. Amit ◽

Veincent Christian F. Pepito ◽

Lourdes Sumpaico-Tanchanco ◽

Manuel M. Dayrit

Keyword(s):

Ecological Model ◽

The Philippines ◽

Vaccine Uptake ◽

Phone Call ◽

Vulnerable Groups ◽

Vaccine Hesitancy ◽

Middle Income ◽

Political Issues ◽

Vaccination Uptake ◽

Vaccine Confidence

Effective and safe COVID-19 vaccines have been developed at a rapid and unprecedented pace to control the spread of the virus, and prevent hospitalisations and deaths. However, COVID-19 vaccine uptake is challenged by vaccine hesitancy and anti-vaccination sentiments, a global shortage of vaccine supply, and inequitable vaccine distribution especially among low- and middle-income countries including the Philippines. In this paper, we explored vaccination narratives and challenges experienced and observed by Filipinos during the early vaccination period. We interviewed 35 individuals from a subsample of 1,599 survey respondents 18 years and older in the Philippines. The interviews were conducted in Filipino, Cebuano, and/or English via online platforms such as Zoom or via phone call. All interviews were recorded, transcribed verbatim, translated, and analysed using inductive content analysis. To highlight the complex reasons for delaying and/or refusing COVID-19 vaccines, we embedded our findings within the social ecological model. Our analysis showed that individual perceptions play a major role in the decision to vaccinate. Such perceptions are shaped by exposure to (mis)information amplified by the media, the community, and the health system. Social networks may either positively or negatively impact vaccination uptake, depending on their views on vaccines. Political issues contribute to vaccine brand hesitancy, resulting in vaccination delays and refusals. Perceptions about the inefficiency and inflexibility of the system also create additional barriers to the vaccine rollout in the country, especially among vulnerable and marginalised groups. Recognising and addressing concerns at all levels are needed to improve COVID-19 vaccination uptake and reach. Strengthening health literacy is a critical tool to combat misinformation that undermines vaccine confidence. Vaccination systems must also consider the needs of marginalised and vulnerable groups to ensure their access to vaccines. In all these efforts to improve vaccine uptake, governments will need to engage with communities to ‘co-create’ solutions.

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Factors Affecting Uptake of Human Papilloma Virus (HPV) Vaccination among in- School Adolescent Girls in Wakiso District, Central Uganda.

10.51168/sjhrafrica.v1i12.11 ◽

2020 ◽

Author(s):

◽

Zaitune Nanyunja

Keyword(s):

Cervical Cancer ◽

Adolescent Girls ◽

Health Workers ◽

Hpv Vaccination ◽

Cluster Sampling ◽

Cross Sectional ◽

Factors Affecting ◽

Five Factors ◽

Vaginal Sex ◽

Depth Interviews

Background: Since 2008, the Human Papillomavirus (HPV) vaccination has been routinely recommended for pre-adolescents and adolescent girls in Uganda. The introduction of HPV vaccines represents a step forward in the primary prevention of cervical cancer and other HPV-related malignancies. This study examines the factors affecting the uptake of HPV vaccination among in-school adolescent girls in Wakiso district to generate information that can be used to improve the uptake of such critical services. Methodology: A cross-sectional analytical study was employed. Both quantitative and qualitative data were collected concurrently. Data were collected from secondary schools in Wakiso district, selected using cluster sampling. Semi-structured self-administered questionnaires were used to collect quantitative data while data from mothers in Wakiso were collected using In-depth interviews through group dialogue sessions. Data were analyzed using SPSS 16.0; characteristics of the sample were summarized by descriptive statistics Results: The findings indicate the HPV vaccination uptake rate as low as 9.2% among the In-school adolescent girls in the Wakiso district. 68.5% belonged to the age group 16-19 (older adolescents). 91.2% had already had vaginal sex and 90.4% had ever had any STI. In the bivariate analyses, five factors were presented to be statistically significant with a P<0.05, implying that these factors were associated with HPV vaccination. They included the occupation of the caretaker, education level of the caretaker, perceived susceptibility to HPV infections and cervical cancer, perceived benefits of HPV vaccination, and knowledge attributes regarding HPV and HPV infections. Conclusion: The Ministry of the health of Uganda and partners should offer ample orientation and training to all health workers and encourage them to disseminate information on HPV vaccination to all eligible adolescents and their caretakers in Wakiso district central Uganda.

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Cost-effectiveness of a bivalent human papillomavirus vaccination program in Japan

Sexual Health ◽

10.1071/sh14241 ◽

2015 ◽

Vol 12 (6) ◽

pp. 520 ◽

Cited By ~ 5

Author(s):

Luke B. Connelly ◽

Ha N. D. Le

Keyword(s):

Cervical Cancer ◽

Human Papillomavirus ◽

Cost Effectiveness ◽

Screening Program ◽

Vaccine Coverage ◽

Precancerous Lesions ◽

Hpv Vaccination ◽

Vaccination Program ◽

Human Papillomavirus Vaccination ◽

The Cost

Background Human papillomavirus (HPV) vaccines and their widespread adoption have the potential to relieve a large part of the burden of cervical cancer morbidity and mortality, particularly in countries that have low screening rates or, like Japan, lack a cohesive universal screening program. An economic evaluation was conducted to assess the cost-effectiveness of introducing a bivalent HPV vaccination program in Japan from a healthcare perspective. Methods: A Markov model of the natural history of HPV infection that incorporates both vaccination and screening was developed for Japan. The modelled intervention, a bivalent HPV vaccine with a 100% lifetime vaccine efficacy and 80% vaccine coverage, given to a cohort of 12-year-old Japanese girls in conjunction with the current screening program, was compared with screening alone in terms of costs and effectiveness. A discount rate of 5% was applied to both costs and utilities where relevant. Results: Vaccination alongside screening compared with screening alone is associated with an incremental cost-effectiveness ratio (ICER) of US$20 315 per quality-adjusted-life-year gained if 80% coverage is assumed. The ICER at 5% coverage with the vaccine plus screening, compared with screening alone, is US$1158. Conclusion: The cost-effectiveness results suggest that the addition of a HPV vaccination program to Japan’s cervical cancer screening program is highly likely to prove a cost-effective way to reduce the burden of cervical cancer, precancerous lesions and HPV16/18-related diseases.

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Knowledge of Cervical Cancer, Human Papilloma Virus (HPV) and HPV Vaccination Among Women in Northeast China

Journal of Cancer Education ◽

10.1007/s13187-019-01582-7 ◽

2019 ◽

Vol 35 (6) ◽

pp. 1197-1205 ◽

Cited By ~ 1

Author(s):

Yu-e Ning ◽

Yao Liu ◽

Xiao-yu Xu ◽

Xin-yu Zhang ◽

Ning Wang ◽

...

Keyword(s):

Cervical Cancer ◽

Human Papilloma Virus ◽

Hpv Vaccine ◽

Family Income ◽

Hpv Vaccination ◽

Northeastern China ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Obvious Effect ◽

Papilloma Virus

AbstractThis study aimed to research the understanding and knowledge of cervical cancer, human papilloma virus (HPV), and HPV vaccination, and the acceptance of HPV vaccination, among a population of women in northeastern China. A cross-sectional survey was carried out by questionnaire to investigate knowledge of cervical cancer, HPV, and HPV vaccination. The 230 female participants were native residents of northeastern China, and their ages ranged between 18 and 65 years. Questionnaires were randomly acquired by the respondents from online and paper questionnaire distribution. The questionnaire included questions on three major aspects to record people’s perceptions of cervical cancer, HPV, and vaccines. Of the sample of 230 women surveyed, 80.9% had heard of cervical cancer, but understanding was only 15.7%; 38.3% knew about HPV; 20% knew about HPV vaccine; 39.6% agreed to receive HPV vaccination, and the remainder were mainly concerned about its safety and effectiveness. Data analysis showed that age, family income, and whether there was experience of screening all influenced knowledge of cervical cancer, but this was not statistically significant. The level of education had no obvious effect on the degree of knowledge about cervical cancer; however, with an improvement in education, women’s awareness of HPV vaccine improved significantly (p < 0.05). Women who have received cervical cancer screening had significantly greater knowledge about cervical cancer and HPV than those with no screening (p < 0.05). Women in northeastern China have little knowledge of cervical cancer, HPV, and HPV vaccine, lack disease knowledge, and hold a skeptical attitude about HPV vaccination. Medical institutions are the main channel providing information to these women.

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