scholarly journals Protection against ischaemia/reperfusion: role of the farnesol and red palm oil

2013 ◽  
Author(s):  
Gergő Szűcs
Keyword(s):  
Palm Oil ◽  
Red Palm Oil ◽  
Ischaemia Reperfusion

scholarly journals The role of gambeir filtrate and red palm oil in the formation of canna starch based-functional edible film

10.5219/1580 ◽  
2021 ◽  
Vol 15 ◽  
pp. 869-876
Author(s):  
Budi Santoso ◽  
Doni Andrian Saragih ◽  
Gatot Priyanto ◽  
Hermanto Hermanto
Keyword(s):  
Water Vapor ◽  
Palm Oil ◽  
Transmission Rate ◽  
Edible Films ◽  
Edible Film ◽  
Water Vapor Transmission Rate ◽  
Red Palm Oil ◽  
Water Vapor Transmission ◽  
Elongation Percentage

This study aims to analyze the role of gambier filtrate and red palm oil in the formation of functional edible film and to determine whether the gambier filtrate and red palm oil are synergistic or antagonistic in the formation of functional edible films. The study design used a factorial randomized block design with two treatment factors and each treatment consisted of three levels, namely: gambier filtrate concentration (A): 20, 30, and 40% (v/v) as well as red palm oil concentration (B): 1.2 and 3% (v/v). The observed parameters were thickness, elongation percentage, water vapor transmission rate, antioxidant activity, and antibacterial activity. Gambier filtrate and red palm oil were capable to improve the antioxidant and antibacterial properties of canna starch-based edible film. Gambier filtrate plays a role in increasing the elongation percentage, thickness, and water vapor transmission rate of edible film.

Antioxidant Rich Red Palm Oil Reduces Myocardial Infarct Size: the Role of MMP-2, Akt and LDH

2010 ◽  
Vol 49 ◽  
pp. S219
Author(s):  
Dirk J. Bester ◽  
Krisztina Kupai ◽  
Tamas Csont ◽  
Gergo Szucs ◽  
Csaba Csonka ◽  
...  
Keyword(s):  
Infarct Size ◽  
Palm Oil ◽  
Myocardial Infarct ◽  
Myocardial Infarct Size ◽  
Red Palm Oil

scholarly journals Dietary red palm oil reduces ischaemia–reperfusion injury in rats fed a hypercholesterolaemic diet

2007 ◽  
Vol 97 (4) ◽  
pp. 653-660 ◽  
Author(s):  
Maritza J. Kruger ◽  
Anna-Mart Engelbrecht ◽  
Johan Esterhuyse ◽  
Eugene F. du Toit ◽  
Jacques van Rooyen
Keyword(s):  
P38 Mapk ◽  
Palm Oil ◽  
Control Diet ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Ischaemia Reperfusion Injury ◽  
Mapk Phosphorylation ◽  
Red Palm Oil ◽  
Ischaemia Reperfusion

We have previously shown that dietary red palm oil (RPO) supplementation improves functional recovery in hearts subjected to ischaemia–reperfusion. However, little knowledge exists concerning the effects of RPO supplementation of a high-cholesterol diet on ischaemia–reperfusion injury. The signalling mechanisms responsible for RPO's effects in the presence of cholesterol also remain to be elucidated. Therefore, the aim of the present study was to examine the effects of RPO, given with a high-cholesterol diet, on mitogen-activated protein kinase (MAPK) phosphorylation and apoptosis. Long–Evans rats were fed a control diet, a control diet containing 2 % cholesterol, or a control diet containing 2 % cholesterol and 7 g RPO per kg (CRPO) for 5 weeks. Hearts were excised and mounted on an isolated working heart perfusion apparatus. Cardiac function was measured after which hearts were freeze-clamped and used to assess MAPK phosphorylation and to evaluate apoptosis. Cholesterol supplementation caused a poor aortic output (AO) recovery compared with the control group (35·5 (sem 6·2) v. 55·4 (sem 2·5) %), but when RPO was added, the percentage AO increased significantly. The cholesterol group's poor AO was associated with a significant increase in p38-MAPK phosphorylation, whereas the CRPO-supplemented group showed as significant reduction in p38-MAPK phosphorylation when compared with the cholesterol-supplemented group. This significant reduction in p38-MAPK was also associated with reduced apoptosis as indicated by significant reductions in caspase-3 and poly(ADP-ribose) polymerase cleavage.

scholarly journals Role of Red Palm Oil in Male Obesity and Infertility Prevention

2021 ◽  
Author(s):  
Folorunso A. Olabiyi ◽  
Yapo G. Aboua ◽  
Thomas K. Monsees
Keyword(s):  
Palm Oil ◽  
Male Fertility ◽  
Negative Impact ◽  
Current Knowledge ◽  
Medical Condition ◽  
Cell Damage ◽  
Experimental Models ◽  
Normal Diet ◽  
Red Palm Oil

The African continent has wide, varied, and rich plant diversity due to its climate. Some of these plants and their products have received tremendous attention due to their benefits in treating and managing ailments that plagues humanity. Red palm oil (RPO) is one of such natural products that have immense nutritional value with ability to ameliorate cardiac- and reproductive-related disorders. In this review article, the current knowledge on the potential of RPO as a phytomedicine to lessen or even prevent the negative impact of obesity on general health status and male fertility was evaluated. This study was done using electronic databases such as PubMed, Scopus, Science Direct, Google Scholar and Web of Science. The study revealed some controversies and inconsistent reports on the effect of RPO on obesity and male fertility which needs further research using appropriate experimental models of obesity. Obesity is known to disrupt male fertility by causing changes to the hypothalamic- pituitary-gonadal axis, thus impairing steroidogenesis and spermatogenesis. As spermatozoa are extremely sensitive towards oxidative stress, a carefully balanced daily supplementation of normal diet with antioxidant-rich RPO might be useful to protect spermatozoa and preserving male fertility. RPO was shown to be useful to protect against or ameliorate toxin- or medical condition-induced male infertility. Also, RPO is packed with powerful antioxidants like carotenoids and vitamin E which helps to prevent cell damage. However, its role in obesity prevention remains a debate.

Role of SOD in the protection of Rhizophora mangle on gastric injury induced by ethanol, ischaemia-reperfusion and acetic acid in rats

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
FM de-Faria ◽  
A Luiz-Ferreira ◽  
ACA Almeida ◽  
V Barbastefano ◽  
MA Silva ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Rhizophora Mangle ◽  
Gastric Injury ◽  
Ischaemia Reperfusion

Role of complement regulatory membrane proteins in ischaemia-reperfusion injury of rat gastric mucosa

1999 ◽  
Vol 14 (10) ◽  
pp. 967-972 ◽  
Author(s):  
Fumihiro Iwata ◽  
Takashi Joh ◽  
Toyohiro Tada ◽  
Noriko Okada ◽  
B Paul Morgan ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Membrane Proteins ◽  
Reperfusion Injury ◽  
Ischaemia Reperfusion Injury ◽  
Ischaemia Reperfusion ◽  
Rat Gastric Mucosa

Nitric oxide: a new role in intensive care

2020 ◽  
Vol 22 (1) ◽  
pp. 72-79
Author(s):  
Alexandra Lee ◽  
◽  
Warwick Butt ◽  
◽  
◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Potential Role ◽  
Nitric Oxide Donors ◽  
Ischaemia Reperfusion Injury ◽  
Surface Receptors ◽  
The Past ◽  
Ischaemia Reperfusion ◽  
Human Experiments ◽  
Endogenous Nitric Oxide

Inhaled nitric oxide has been used for 30 years to improve oxygenation and decrease pulmonary vascular resistance. In the past 15 years, there has been increased understanding of the role of endogenous nitric oxide on cell surface receptors, mitochondria, and intracellular processes involving calcium and superoxide radicals. This has led to several animal and human experiments revealing a potential role for administered nitric oxide or nitric oxide donors in patients with systemic inflammatory response syndrome or ischaemia–reperfusion injury, and in patients for whom exposure of blood to artificial surfaces has occurred.

Red Palm Oil Supplementation: A Feasible Diet-Based Approach to Improve the Vitamin A Status of Pregnant Women and Their Infants

2003 ◽  
Vol 24 (2) ◽  
pp. 208-217 ◽  
Author(s):  
M. S. Radhika ◽  
P. Bhaskaram ◽  
N. Balakrishna ◽  
B. A. Ramalakshmi
Keyword(s):  
Vitamin A ◽  
Palm Oil ◽  
Controlled Study ◽  
Control Group ◽  
Serum Retinol ◽  
Groundnut Oil ◽  
Red Palm Oil ◽  
Vitamin A Status ◽  
Increased Risk ◽  
The Mean

This double-blinded, randomized, controlled study was designed to study the effect of dietary supplementation with red palm oil during pregnancy on maternal and neonatal vitamin A status. A total of 170 women were recruited at 16 to 24 weeks of gestation and randomly assigned to an experimental group that received red palm oil to supply approximately one recommended dietary amount (RDA) (2,400 μg) of β-carotene or to a control group that received an equivalent volume of groundnut oil. The women received the oils for a period of 8 weeks, starting at 26 to 28 weeks of gestation and extending to 34 to 36 weeks of gestation. The mean postintervention (34 to 36 weeks) levels of serum retinol were 1.20 ± 0.22 (SD) μmol/L (95% CI, 1.15–1.25) in women receiving red palm oil and 0.73 ± 0.15 μmol/L (95% CI, 0.69–0.77) in their infants; these levels were significantly higher than those in women receiving groundnut oil (1.07 ± 0.26 μmol/L; 95% CI, 1.01–1.13; p < .01) and their infants (0. 62 ± 0.17 μmol/L; 95% CI, 0.57–0.67; p < .001). A significantly lower proportion of women in the red palm oil group than in the control group had vitamin A deficiency (serum retinol levels < 0.7 μmol/L) after intervention (1.5% vs. 9.7%). The proportion of women having anemia was significantly lower (p < .01) in the red palm oil-supplemented group (80.6%) than in the control group (96.7%). The mean birthweight and gestational age of the infants did not differ significantly between the two groups. An increased risk of low birthweight (p = . 003) and preterm delivery (p = . 000) was observed with decreasing serum retinol levels in the third trimester of pregnancy. These results show that red palm oil supplementation significantly improved maternal and neonatal vitamin A status and reduced the prevalence of maternal anemia. Maternal vitamin A status in the later part of pregnancy is significantly associated with fetal growth and maturation. Hence red palm oil, a rich source of bioavailable vitamin A, could be used as a diet-based approach for improving vitamin A status in pregnancy.

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