scholarly journals Actual ambulatory care in patients with type 2 diabetes mellitus in Russian Federation according to open label prospectiveobservational study DIA-CONTROL

2011 ◽  
Vol 14 (4) ◽  
pp. 75-80 ◽  
Author(s):  
Marina Vladimirovna Shestakova
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Ambulatory Care ◽  
Prospective Observational Study ◽  
Open Label ◽  
Hypoglycemic Therapy ◽  
Dm Type 2 ◽  
Hba1c Levels

This review presents a comprehensive analysis of actual ambulatory care in patients with type 2 diabetes mellitus provided in 10 federal subjects withinthe period of 1 year. The analysis is based on results from non-interventional open label prospective observational study DIA-CONTROL, whichincluded 9844 patients with DM type 2. The study was aimed to assess the initial level of glycated hemoglobin and its further dynamics according tomeasurements repeated every 3 months. Composition and efficiency of hypoglycemic therapy were also estimated in these patients.Inclusion visit showed 38.5% of patients to have adequate HbA1c levels (8%, which is quite disturbing and suggests a more careful approach to instruction of healthcarespecialists.

scholarly journals TheType 2 Deiodinase Thr92Ala PolymorphismIs Associated with Worse Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Xiaowen Zhang ◽  
Jie Sun ◽  
Wenqing Han ◽  
Yaqiu Jiang ◽  
Shiqiao Peng ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Meta Analysis ◽  
Increased Risk ◽  
Design And Methods ◽  
Hba1c Levels

Objective. Type 2 deiodinase (Dio2) is an enzyme responsible for the conversion of T4 to T3. The Thr92Ala polymorphism has been shown related to an increased risk for developing type 2 diabetes mellitus (T2DM). The aim of this study is to assess the association between this polymorphism and glycemic control in T2DM patients as marked by the HbA1C levels.Design and Methods.The terms “rs225014,” “thr92ala,” “T92A,” or “dio2 a/g” were used to search for eligible studies in the PubMed, Embase, and Cochrane databases and Google Scholar. A systematic review and meta-analysis of studies including both polymorphism testing and glycated hemoglobin (HbA1C) assays were performed.Results. Four studies were selected, totaling 2190 subjects. The pooled mean difference of the studies was 0.48% (95% CI, 0.18–0.77%), indicating that type 2 diabetics homozygous for the Dio2 Thr92Ala polymorphism had higher HbA1C levels.Conclusions. Homozygosity for the Dio2 Thr92Ala polymorphism is associated with higher HbA1C levels in T2DM patients. To confirm this conclusion, more studies of larger populations are needed.

scholarly journals ADHERENCE LEVEL AND BLOOD SUGAR CONTROL OF TYPE 2 DIABETES MELLITUS PATIENTS WHO GETS COUNSELING AND SHORT MESSAGES SERVICE AS REMINDER AND MOTIVATION

2018 ◽  
Vol 11 (2) ◽  
pp. 219 ◽  
Author(s):  
Wirawan Adikusuma ◽  
Nurul Qiyaam
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Medication Adherence ◽  
Treatment Adherence ◽  
Data Retrieval ◽  
Control Group ◽  
Hba1c Levels ◽  
Short Messages

  Objective: Examines the effects of counseling and short messages service (SMS) as a reminder and motivation toward medication adherence improvement and controlled HbA1c levels of type 2 diabetes mellitus (T2DM) patients.Methods: This study used a quasi-experimental method with prospective data retrieval. The subjects of this study were 40 patients with outpatient T2DM in internal disease polyclinic in West Nusa Tenggara Hospital, Indonesia. Patients who fulfilled the inclusion criteria were divided into two groups: The control group (n=20) receiving only the drug care service and the treatment group (n=20) receiving counseling and SMS reminder and motivation from the pharmacist. Data collecting was conducted using the pill count method, and HbA1c levels were taken from the medical record.Results: The results showed that counseling and SMS as reminder and motivation by a pharmacist can improve treatment adherence significantly (p<0.05) by 11.33 ± 8.47 and can decrease HbA1c level significantly (p<0.05) of 1.32 ± 0.72 in the intervention group. There was a positive correlation between T2DM patient treatment adherence to HbA1c levels (r=0.254, p=0.023).Conclusion: The provision of counseling and SMS as a reminder and motivation by the pharmacist can have a positive effect toward medication adherence and control of HbA1c in T2DM patients. 

scholarly journals Correlation Between Lipid Profile with Type 2 Diabetes Mellitus Progression

2020 ◽  
Vol 8 (2) ◽  
pp. 66-72
Author(s):  
Angiesta Pinakesty ◽  
Restu Noor Azizah
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Lipid Profile ◽  
Cholesterol Levels ◽  
Type 2 Dm ◽  
Hba1c Levels

Introduction: Diabetes mellitus (DM) is a non-communicable disease that has increased from year to year. Type 2 diabetes mellitus is not caused by lack of insulin secretion, but is caused by the failure of the body's cells to respond to the hormone insulin (insulin resistance). Insulin resistance was found to be a major contributor to atherogenic dyslipidemia. Dyslipidemia in DM risks 2 to 4 times higher than non-DM. Although dyslipidemia has a great risk for people with type 2 diabetes mellitus, this conventional risk factor only explains a portion (25%) of excess cardiovascular risk in type 2 DM. Discussion: In uncontrolled type 2 DM patients, LDL oxidation occurs faster which results from an increase in chronic blood glucose levels. Glycemic control as a determinant of DM progressivity is determined through HbA1c examination. HbA1c levels are associated with blood triglyceride levels. Meanwhile, triglyceride levels are associated with total cholesterol and HDL cholesterol levels. HbA1c levels are also associated with LDL cholesterol levels. Conclusion: There is a relationship between lipid profile and the progression of type 2 diabetes mellitus.   Keywords: type 2 diabetes mellitus, dyslipidemia, HbA1c, glycemic control, lipid profile

scholarly journals HBA1C LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS WITH AND WITHOUT INCIDENCE OF THROMBOTIC STROKE (Kadar HbA1c Pasien Diabetes Melitus Tipe 2 dengan dan Tanpa Kejadian Strok Infark Trombotik)

2018 ◽  
Vol 23 (1) ◽  
pp. 56
Author(s):  
Dafina Balqis ◽  
Yudhi Adrianto ◽  
Jongky Hendro Prayitno
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Hba1c Levels ◽  
Diabetes Melitus

Strok saat ini menjadi salah satu penyebab utama kematian global. Hubungan antara kejadian strok dengan diabetes telahlama diketahui. Kontrol gula darah, yang dipantau melalui kadar HbA1c, telah menunjukkan hubungan dengan strok dan penyakitkardiovaskular lain. Kajian ini untuk menentukan perbedaan kadar HbA1c antara pasien diabetes melitus tipe 2 dengan dan tanpakejadian strok infark trombotik. Metode penelitian yang digunakan adalah analisis retrospektif menggunakan rekam medis pasienselama 3,5 tahun. Penelitian ini mengumpulkan data kadar HbA1c dari 443 pasien diabetes melitus tipe 2 kemudian membandingkanrerata kadar HbA1c antara pasien diabetes mellitus tipe 2 dengan kejadian strok trombotik (n=74) dan tanpa kejadian strok trombotik(n=369). Perbandingan tingkat HbA1c juga dilakukan secara terpisah antara laki-laki dan perempuan. Kajian ini menemukan reratakadar HbA1c yang tinggi di kedua kelompok sampel (10,49%±2,53% untuk kelompok dengan kejadian strok infark trombotik dan10,44%±2,8% untuk kelompok tanpa kejadian strok infark trombotik) dengan perbandingan sarana p>0,05. Perbandingan yangdilakukan secara terpisah di laki-laki dan perempuan juga menunjukkan hasil yang sama dengan p>0,05. Sebagai simpulan, kadarHbA1c di kedua kelompok penelitian sama-sama tinggi dan tidak ada perbedaan bermakna kadar HbA1c yang ditemukan di pasiendengan diabetes tipe 2 dengan dan tanpa kejadian strok trombotik.

scholarly journals A patient who does not like insulin

ABOUTOPEN ◽  
2018 ◽  
Vol 4 (1) ◽  
pp. 122-125
Author(s):  
Paola Ubaldi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
General Population ◽  
Bone Metastases ◽  
Cancer Symptoms ◽  
The Past ◽  
The Right ◽  
Hypoglycemic Therapy

Hypoglycemic therapy over the past 20 years has expanded considerably with the use of new classes of more effective and safer medicines. Alongside the aging of the general population, the survival of diabetic subjects has significantly increased, thus exposing them to a greater risk of developing co-morbidities. This represents a challenge for the diabetologist, who must acquire ever broader concepts for the management of a complex and multi-organ disease. We report the case of a 72-year-old woman with type 2 diabetes mellitus and pulmonary adenocarcinoma of the right upper lobe with brain and bone metastases who, subjected to innovative and integrated treatments agreed between specialists of different disciplines, is still alive and free of cancer symptoms 23 months after diagnosis (Diabetology)

scholarly journals Alteration of salivary microbiome in periodontitis with or without type-2 diabetes mellitus and metformin treatment

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Xiaoyu Sun ◽  
Meihui Li ◽  
Li Xia ◽  
Zhaohui Fang ◽  
Shenjun Yu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Rrna Gene ◽  
Ralstonia Pickettii ◽  
Health Group ◽  
Significant Difference ◽  
Rrna Gene Sequencing ◽  
Hypoglycemic Therapy

Abstract We aimed to explore the effects of type-2 diabetes mellitus (T2DM) and hypoglycemic therapy on the salivary microbiome in periodontitis patients and identify the potential salivary micro-biomarker for the early warning of T2DM. Saliva samples were collected from healthy individuals (Health), periodontitis patients (P), T2DM patients, periodontitis patients with T2DM (DAP), and DAP patients treated with Metformin (Met). Samples were determined by16S rRNA gene sequencing. 29 phyla, 322 genera, and 333 species of salivary microbiome were annotated. Compared to the Health group, the P and DAP group showed a significantly higher diversity of saliva microbiota, while the T2DM and Met group had no significant difference in microbial abundance but showed a trend of increasing diversity. Other than well-known periodontitis-inducing pathogens, the proportion of Prevotella copri, Alloprevotella rava, and Ralstonia pickettii, etc. were also significantly increased in periodontitis patients with or without T2DM. After effective glycemic control, the abundance of Prevotella copri, Alloprevotella rava, Ralstonia pickettii, etc. decreased in periodontitis patients with companion T2DM. The accuracies of the classification models in differentiating Health-vs.-P, DAP-vs.-P, and T2DM-vs.-P were 100%, 96.3%, and 98.1%, respectively. Hypoglycemic therapy could reconstruct the saliva microbiota and hence improve the localized conditions of diabetes patients with periodontitis.

scholarly journals Influence of Glycated Haemoglobin Levels on Intraocular Pressure in patients with Type –II Diabetes Mellitus

2019 ◽  
Vol 11 (1) ◽  
pp. 19-23
Author(s):  
Ajai Agrawal ◽  
Shubham Ahuja ◽  
Anupam Singh ◽  
Ramanuj Samanta ◽  
Sanjeev Kumar Mittal
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Intraocular Pressure ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Group I ◽  
Hba1c Levels

Introduction: Patients with diabetes mellitus are at a higher risk of developing primary open angle glaucoma (POAG) as compared to non-diabetic patients. Objectives: To determine whether there is a correlation between hyperglycemic levels and intraocular pressure (IOP) and to identify patients of Type II diabetes mellitus who are at a higher risk of developing glaucoma. Materials and Methods: This was a hospital based, cross sectional study performed on patients with type II diabetes mellitus, at a tertiary health care center in Uttarakhand, India between July, 2018 and September, 2018. 318 eyes of 159 patients with Type2 diabetes mellitus were included in the study. IOP was measured by Goldmannappla nation to no meter and central corneal thickness was measured with specula microscope in all patients, in addition to glycated hemoglobin levels (HbA1c) and fasting and post-prandial blood glucose levels. The data was analysed using SPSS 22 software. Results: Mean IOP was found to be 15.75 ± 3.18 mm Hg in patients with HbA1c levels between 6.5%-12% (Group I) and 17.42 ± 2.67 mm Hg in patients with HbA1c levels more than 12 % (Group II). The difference between the two groups was statistically significant (P =0.013). Out of 159 patients with Type 2 Diabetes mellitus, a total of 11 patients had IOP more than 21mm Hg in one or both the eyes. Conclusion: Hyperglycaemic levels as determined by raised HbA1c levels are associated with higher intraocular pressures in patients with type 2 diabetes mellitus.

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