The effect of normobaric hypoxia on the secretion of insulin and growth hormone

2019 ◽  
Vol 44 (2) ◽  
pp. 7-9
Author(s):  
N. T. Starkova ◽  
A. L. Davydov ◽  
A. V. Koroleva
Keyword(s):  
Growth Hormone ◽  
Body Weight ◽  
Normal Subjects ◽  
Normobaric Hypoxia ◽  
Hypoxic Exposure ◽  
Control Group ◽  
Somatotropic Hormone ◽  
Weight Index ◽  
Glycemia Level ◽  
Body Weight Index

Effect of normobaric hypoxia on insulin (IRI) and somatotropic hormone (STH) secretion was studied in 24 normal subjects aged 35-55 years. Control group consisted of 18 subjects administered placebo. Adaptation to normobaric hypoxia was attended by changes in IRI and STH but not in the glycemia level. Hypoxic exposure was associated with an increase of the plasma STH concentration and a tendency to normalization of IRI in all examinees. These parameters correlated with body weight index.

scholarly journals PROPHYLACTIC EFFECT OF COENZYME Q10 ON GROSS PARAMETERS OF RAT TESTIS EXPOSED TO MOSQUITO COIL SMOKE INHALATION

2021 ◽  
Vol 71 (2) ◽  
pp. 427-32
Author(s):  
Muhammad Fahad Atta ◽  
Khadija Qamar ◽  
Maria Iram ◽  
Saba Saleem Safdar ◽  
Tayyaba Faisal ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Coenzyme Q10 ◽  
Smoke Inhalation ◽  
Control Group ◽  
Mosquito Coil ◽  
Rat Testis ◽  
Weight Index ◽  
Testicular Weight ◽  
Body Weight Index

Objective: To determine the toxic effect of mosquito coil smoke inhalation on gross parameters of rat testis and explore the protective effect of Coenzyme Q10on testicular toxicity profile. Study Design: Laboratory-based experimental study. Place and Duration of Study: Department of Anatomy Army Medical College, Rawalpindi in collaboration with National Institute of Health, Islamabad, from Jan 2020 to Dec 2020. Methodology: This study was carried out among 30 male Sprague Dawley rats, distributed into three groups as 10 rats/group; group A served as control group, rats in group B were exposed to allethrin-based mosquito coil smoke 4hours/day for 12 weeks. Rats in group C were administered Coenzyme Q10 (10 mg/kg/day) via oral gavage for 12 weeks along with mosquito coil smoke exposure. At the end of study, gross parameters of body weight gain, testicular weight and volume, and relative tissue body weight index of testis were compared among groups. Results: Rats exposed to mosquito coil smoke alone showed significantly less weight gain (p<0.001)), testicular weight (p<0.001), volume (p<0.001), and relative tissue body weight index (p<0.001) as compared to control group. Rats administered Coenzyme Q10 along with mosquito coil smoke exposure exhibited significantly higher weight gain (p<0.001), testicular weight (p<0.001), volume (p<0.001) and relative tissue body weight index (p<0.001) as compared to rats exposed to mosquito coil smoke alone. Conclusion: Long-term inhalation of allethrin-based mosquito coil smoke caused testicular atrophy among rats, as evident by reduced testicular weight, volume and relative tissue body weight index. Whereas, prophylactic oral administration of Coenzyme......................

scholarly journals ANALYSIS OF THE BASIC ANTHROPOMETRIC MEASUREMENT PARAMETERS OF DENTAL PATIENTS WITH CONNECTIVE TISSUE DYSPLASIA

2018 ◽  
Vol 22 (1) ◽  
pp. 45-49
Author(s):  
Elena E. Statovskaia
Keyword(s):  
Body Weight ◽  
Connective Tissue ◽  
Anthropometric Measurement ◽  
Control Group ◽  
Basic Group ◽  
Weight Index ◽  
Dental Patients ◽  
Connective Tissue Dysplasia ◽  
And Gender ◽  
Body Weight Index

The purpose of this study was to determine the bodybuild, the basic anthropometric measurement parameters (body-weight index - BMI, Varga Index - VI, height, weight), the nature of variation thereof in relation to sex, age and possible correlation with dental health status, in adult patients with connective tissue dysplasia (CTD). A group of 360 dental patients of white race, aged 16-56, residents of St. Petersburg, including: control group of patients (n=84) not having the connective tissue dysplasia (CTD) and the basic group of patients (n=276) having the CTD, has been examined. Patients underwent complex clinical and instrumental examination of their dental, somatic status, CTD check. We have found that BMI, in comparison with VI, identifies the differences between the studied groups more accurately, and seems more preferable for diagnosis of the nutritional status and differential diagnosis of patients whether having or not having CTD. In the basic group, BMI is affected by the course of CTD and by age. In the control group, BMI is affected by age and gender. In the basic group, the course of CTD and gender affect VI. In the control group, gender and age affect VI. Correlations of the anthropometric parameters (n=320; p=0,0001) with CTD and dental parameters, have been identified. Varga Index has positive correlations with body-weight index, BMI (r=0.951), weight (r=0,837), periodontal biotype (r=0,289), and negative correlations with CTD (r = -0.290). BMI positively correlates with VI (r= 0,951), weight (r=0,856), and age (r=0.392), gingiva biotype (r=0,305), presence of dentition defects (r=0,301). BWI negatively correlates with the diagnostic bone criteria of CTD (r=-0,308; n=249) and the CTD phenotype (r=-0,323). In the examined patients, age correlates with the CFE index (index of caries-decayed, filled, extracted teeth) (r=508) positively, and correlates with the weight (r=-0.300) of the patient negatively (p=0,0001; n=320). Implementing the study of dental patients, it is necessary to take into account the values and correlations of the anthropometric measurement parameters (BMI, VI of weight, height), which correlate with age, gender and dental status characteristics (periodontal biotypes, CFE, dentition defects), as well as bone diagnostic criteria of CTD, feature of the CTD course and phenotype.

scholarly journals MODIFIED LOW-DENSITY LIPOPROT EINS IN DI ABETES MELLITUS TYPE 2

The Clinician ◽  
2018 ◽  
Vol 12 (1) ◽  
pp. 29-35
Author(s):  
O. M. Drapkina ◽  
В. B. Gegenava
Keyword(s):  
Body Weight ◽  
Blood Glucose Concentration ◽  
Control Group ◽  
Low Density ◽  
Factors Affecting ◽  
Weight Index ◽  
Patients With Diabetes ◽  
Group 2 ◽  
Body Weight Index

 Objective:to compare the level of modified low-density lipoproteins (mLDL) in patients with diabetes mellitus type 2 (DM2) and without DM2; to identify the factors affecting mLDL сontent.Materials and methods.The study involved 64 patients; they were divided into 2 groups. The main group included 32 patients with DM2 (15 men and 17 women, median age – 65 years), the control group 2 included 32 patients without DM2 (15 men and 17 women, median age – 60.5 years). All patients (100 %) had arterial hypertension. Both groups were generally comparable in the main clinical and laboratory characteristics. Mann–Whitney test, Spearman correlation coefficient were used for statistical data processing.Results. In patients with DM2 mLDL level was significantly higher (р <0.001) and correlated with blood glucose concentration (p = 0.021), glycated hemoglobin values (p <0.001) and body-weight index (p = 0.007). In patients without DM2 mLDL level correlated with bodyweight index (p <0.001). No correlation between mLDL level and standard LDL content was found in patients with DM2 and in patients without DM2 (p = 0.714 and p = 0.758 respectively).Conclusion.DM2 is significantly associated with an increased mLDL level that is affected by parameters of carbohydrate metabolism and body-weight index. In persons without hyperlipidemia mLDL level increases in case of hyperglycemia.

scholarly journals Стимуляція продукції гормону росту у ягнят і поросят під дією Гамавіту

2017 ◽  
Vol 19 (77) ◽  
pp. 63-66
Author(s):  
A.V. Sanin ◽  
A.V. Deyeva ◽  
A.N. Narovlyansky ◽  
A.V. Pronin ◽  
V.V. Behalo
Keyword(s):  
Growth Hormone ◽  
Body Weight ◽  
Veterinary Medicine ◽  
Body Weight Gain ◽  
The United States ◽  
Control Group ◽  
The European Union ◽  
Feed Conversion ◽  
Suckling Piglets ◽  
Experimental Group

Among the most important issues of food safety, which conducted an extensive international discussion, is the use in livestock of drugs, such as recombinant bovine growth hormone, or somatotropin, and, in particular, ractopamine, stimulating the growth of cattle, pigs and poultry. Ractopamine is used in veterinary medicine to increase the meatiness of the carcass. Ractopamine improves feed conversion, reduces body fat through lipolysis and an intense muscle-building. In the United States, Australia, Argentina, Brazil, Canada and many other countries, ractopamine is allowed for usage as growth stimulator in livestock. However, in most countries of the European Union the use of ractopamine is forbidden. In this regard, it seems very important to develop effective and safe drugs that can stimulate the production of endogenous somatotropic hormone (STH). We propose to use for this purpose Gamavit – well-studied veterinary medicine stimulating metabolism and widely used by veterinary specialists in the Russian Federation, Ukraine, Belarus and some other countries. The aim of this work was to study the effect of Gamavit on STH production in suckling piglets and lambs. Previously it was shown elsewhere that Gamavit induced 2-fold increase in the STH blood level in calves. The experiment was done using 30 suckling piglets of Landrace breed at the age of 0 to 7 days and 10 newborn lambs of the Stavropol breed. All animals were kept in identical conditions, they were fed the same balanced diet. The study was conducted according to the following protocol: The piglets of the 1st group (control) received 0.9% NaCl solution at a dose of 0.5 ml/kg intramuscularly on the 1st, 2nd, 3rd and 5th days of the experiment. Piglets of group 2 (experimental) were inoculated with Gamavit at a dose of 0.5 ml/kg intramuscularly on the 1st, 2nd, 3rd and 5th days of the experiment. Lambs were inoculated with Gamavit at a dose of 0.5 ml/kg of body weight on 7th, 14th and 21st days after birth. Using method of enzyme immunoassay we shown that during the study level of STH in the experimental group of piglets inoculated with Gamavit gradually increased from 8.5 mIU/l before the experiment to 14.3 mIU/l on the 5th day. In the control group it ranged from 7.5 mIU/l to 10.2 mIU\l. At the end of the experiment greatest body weight gain was observed in the experimental group and amounted 45.450 g compared with 26,700 g in the control group piglets. In the experimental group of newborn lambs Gamavit induced raise in the STH serum level 2 from 6.5 mIU/l at day 0 to 13.1 mIU/l at day 21. Thus, Gamavit, unlike synthetic growth hormone, ractopamine and other beta-agonists used in livestock, induces the production of endogenous STH, which stimulates growth of the animal, while being safe and rapidly metabolizing on its own metabolic pathway.

Correlation of Allograft Weight to Recipient Body Weight Index on Renal Function in Kidney Transplantation

2016 ◽  
Vol 48 (2) ◽  
pp. 578-582 ◽  
Author(s):  
L. García-Covarrubias ◽  
C. Pliego ◽  
L. Bermudez ◽  
A. Cicero ◽  
J. Cancino ◽  
...  
Keyword(s):  
Renal Function ◽  
Body Weight ◽  
Kidney Transplantation ◽  
Weight Index ◽  
Body Weight Index

Using r-K Selection Theory to Predict Natural Mortality

1980 ◽  
Vol 37 (12) ◽  
pp. 2266-2271 ◽  
Author(s):  
Donald R. Gunderson
Keyword(s):  
Body Weight ◽  
Life History ◽  
Growth Parameters ◽  
Stepwise Multiple Regression ◽  
Natural Mortality ◽  
Instantaneous Rate ◽  
Life History Parameters ◽  
Selection Theory ◽  
Weight Index ◽  
Body Weight Index

Theory on r-K selection is used as a basis for examining correlations between instantaneous rate of natural mortality (M), gonad-body weight index, age at maturity, longevity, and Bertalanffy growth parameters (k, L∞) for 10 species of marine fish. All correlations were consistent with r-K selection theory. The gonad-body weight index was found to be more highly correlated with M than any of the other life history parameters examined (r2 = 0.62), and stepwise multiple regression showed that additional variables added little to the predictive ability of the model. The gonad-body weight index appears to be quite useful in predicting M, and development of an analogous index on an energetics basis might enhance its utility in this regard.Key words: natural mortality, r-K selection, life history parameters

Investigation of the influence of body weight index to the result of therapeutic erythrocytapheresis in patients with polycythemia vera

2012 ◽  
Vol 47 (3) ◽  
pp. 295-299 ◽  
Author(s):  
Jie Bai ◽  
Lei Zhang ◽  
Xiao Hu ◽  
Yangping Xue ◽  
Fenglei Long ◽  
...  
Keyword(s):  
Body Weight ◽  
Polycythemia Vera ◽  
Weight Index ◽  
Body Weight Index
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