Single-Center Retrospective Study of Risk Factors and Predictive Value of Framingham Risk Score of Patients with ST Elevation Myocardial Infarction

2018 ◽  
Vol 111 (4) ◽  
pp. 226-229
Author(s):  
Sohail Ikram ◽  
Ajay Pachika ◽  
Henrike Schuster ◽  
Aman Ghotra ◽  
Laura Dotson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Retrospective Study ◽  
Risk Score ◽  
Predictive Value ◽  
Framingham Risk Score ◽  
St Elevation Myocardial Infarction ◽  
Single Center ◽  
Framingham Risk ◽  
St Elevation

scholarly journals Gambaran kelainan katup jantung pada pasien infark miokard di RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari 2015-31 Desember 2015

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Mawarni I.S. Tumbel ◽  
Agnes L. Panda ◽  
Janry Pangemanan
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Retrospective Study ◽  
Heart Valve ◽  
St Elevation Myocardial Infarction ◽  
Papillary Muscles ◽  
Age Group ◽  
Cross Sectional ◽  
St Elevation ◽  
Cross Sectional Design

Abstract: Myocardial infarction is divided into STEMI (ST elevation myocardial infarction) and NSTEMI (Non ST elevation myocardial Infarction). According to location, infarction consists of inferior, lateral, and aortal. Inferior infarction often causes mitral valve and aortal abnormality due to papillary muscles rupture. This study was aimed to obtain the description of heart valve abnormality in myocardial infarction patients at Prof. Dr. R. D Kandou Hospital Manado from January 2015 to December 2015. This was a retrospective study with a cross sectional design. The results showed that there were 20 cases (90.9%) of NSTEMI and 2 cases (9.1%) of STEMI. The most location of infarction was inferior accounted for 10 cases (45.5%). The most heart valve abnormalities were combination abnormality accounted for 16 cases (72.7%); most were mild MR (5 cases; 55.6%), mild PR (5 cases; 55.6%), and mild TR (3 cases; 33.3%) in NSTEMI cases dominated by male cases (54.5%) and age group 56-66 years (40.9%), and combination of 4 major risk factors (59.1%).Keywords: description, heart valve abnormality, myocardial infarction Abstrak: Infark miokard terbagi menjadi STEMI (ST elevation myocardial infarction) dan NSTEMI (Non ST elevation myocardial infarction). Infark berdasarkan lokasi terdiri atas inferior, lateral, anterior dan aorta. Infark inferior sering menyebabkan kelainan katup mitral dan aorta akibat ruptur muskulus papilaris. Penelitian ini bertujuan untuk mengetahui gambaran kelainan katup jantung pada pasien infark miokard di RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari 2015 - 31 Desember 2015. Jenis penelitian ialah retrospektif dengan desain potong lintang. Hasil penelitian mendapatkan 20 kasus (90,9%) NSTEMI dan 2 kasus (9,1%) STEMI. Lokasi infark terbanyak yaitu inferior sebanyak 10 kasus (45,5%), didapati kelainan katup terbanyak yaitu kombinasi sebanyak 16 kasus (72,7%), dengan derajat terbanyak yaitu MR mild 5 kasus (55,6%), PR mild 5 kasus (55,6%) dan TR mild sebanyak 3 kasus (33,3%) pada pasien NSTEMI, yang didominasi oleh pasien laki-laki (54,5%), usia 56 – 66 tahun (40,9%), yang memiliki 4 faktor resiko mayor (59,1%). Kata kunci: gambaran, kelainan katup, infark miokard.

Risk factors of coronary microvascular obstruction (Preprint)

2020 ◽  
Author(s):  
Yong Li ◽  
Shuzheng Lyu
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Logistic Regression ◽  
Microvascular Obstruction ◽  
Coronary Intervention ◽  
St Elevation Myocardial Infarction ◽  
Neutrophil Percentage ◽  
Percutaneous Coronary ◽  
St Elevation

BACKGROUND Coronary microvascular obstruction /no-reflow(CMVO/NR) is a predictor of long-term mortality in survivors of ST elevation myocardial infarction (STEMI) underwent primary percutaneous coronary intervention (PPCI). OBJECTIVE To identify risk factors of CMVO/NR. METHODS Totally 2384 STEMI patients treated with PPCI were divided into two groups according to thrombolysis in myocardial infarction(TIMI) flow grade:CMVO/NR group(246cases,TIMI 0-2 grade) and control group(2138 cases,TIMI 3 grade). We used univariable and multivariable logistic regression to identify risk factors of CMVO/NR. RESULTS A frequency of CMVO/NR was 10.3%(246/2384). Logistic regression analysis showed that the differences between the two groups in age(unadjusted odds ratios [OR] 1.032; 95% CI, 1.02 to 1.045; adjusted OR 1.032; 95% CI, 1.02 to 1.046 ; P <0.001), periprocedural bradycardia (unadjusted OR 2.357 ; 95% CI, 1.752 to 3.171; adjusted OR1.818; 95% CI, 1.338 to 2.471 ; P <0.001),using thrombus aspirationdevices during operation (unadjusted OR 2.489 ; 95% CI, 1.815 to 3.414; adjusted OR1.835; 95% CI, 1.291 to 2.606 ; P =0.001),neutrophil percentage (unadjusted OR 1.028 ; 95% CI, 1.014 to 1.042; adjusted OR1.022; 95% CI, 1.008 to 1.036 ; P =0.002) , and completely block of culprit vessel (unadjusted OR 2.626; 95% CI, 1.85 to 3.728; adjusted-OR 1.656;95% CI, 1.119 to 2.45; P =0.012) were statistically significant ( P <0. 05). The area under the receiver operating characteristic curve was 0.6896 . CONCLUSIONS Age , periprocedural bradycardia, using thrombus aspirationdevices during operation, neutrophil percentage ,and completely block of culprit vessel may be independent risk factors for predicting CMVO/NR. We registered this study with WHO International Clinical Trials Registry Platform (ICTRP) (registration number: ChiCTR1900023213; registered date: 16 May 2019).http://www.chictr.org.cn/edit.aspx?pid=39057&htm=4. Key Words: Coronary disease ST elevation myocardial infarction No-reflow phenomenon Percutaneous coronary intervention

The utility of coronary artery calcium in non-gated high resolution CT thorax scans in predicting cardiac events as compared to the Framingham risk score: a retrospective study

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
S Saluja ◽  
H Contractor ◽  
M Daniells ◽  
J Sobolewska ◽  
K Khan ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Retrospective Study ◽  
Coronary Artery ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Cardiac Events ◽  
End Point ◽  
Framingham Risk ◽  
Good Concordance

Abstract Background There is existing evidence to suggest a correlation between coronary artery calcification (CAC) measured using ECG-triggered chest computed tomography and cardiovascular disease. Further evidence has emerged to suggest a correlation between CAC measured using non-gated CT scans and cardiovascular disease. Herein, we sought to ascertain the utility of incidental findings of CAC on non-triggered high resolution CT (HRCT) thorax used for patients undergoing lung cancer screening or follow-up for interstitial lung disease and Framingham risk score (FRS) in predicting cardiovascular events. Methods The Computerised Radiology Information Service (CRIS) database was manually searched to determine all HRCT scans performed in a single trust from 05/2015 to 05/2016. The reports issued by Radiologists and images of selected studies were reviewed. For patients with CAC, we calculated the calcium score for patients using the Agatston method. Clinical events were determined from the electronic medical record without knowledge of patients' CAC findings. For these patients, the Framingham Risk Score (FRS) was also calculated. The primary end point of the study was composite of all-cause mortality and cardiac events (non-fatal myocardial infarction, coronary revascularization, new atrial fibrillation or heart failure episode requiring hospitalization). Results We selected 300 scans from a total of approximately 2000 scans performed over this time. Data at follow up was available for 100% of the patients, with a median duration of follow up of 1.6 years. Moderate to severe CAC was found in 35% of people. Multivariable analysis showed good concordance between CAC and FRS in predicting composite clinical end point. The Odds Ratio for cardiac events in patients with moderate to severe CAC was 5.3 (p&lt;0.01) and for composite clinical end point was 3.4 (p&lt;0.01). This is similar to the OR predicted by the FRS: 4.8; p&lt;0.01 and 3.1; p&lt;0.01 respectively. Only 6.2% of patients with moderate to severe CAC were currently statin treated. Conclusion In this retrospective study of patients with respiratory disease attending for HRCT scanning, co-incidentally detected CAC predicts cardiac events, with good concordance with the FRS. The incidental finding of CAC on non-gated CT scanning should be reported with Agatston score calculation allowing consideration of intervention to mitigate cardiovascular risk and optimize. Further multi-centre prospective studies of this strategy, with a larger patient cohort should be conducted to clarify the utility of CAC as a prediction tool to modify cardiac risk. Funding Acknowledgement Type of funding source: None

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