scholarly journals Anticipatory extended cholecystectomy

2021 ◽  
Vol 25 (1) ◽  
pp. S316-S316
Author(s):  
Mukteshwar DASARI ◽  
Vinay Kumar KAPOOR
Keyword(s):  
Extended Cholecystectomy

scholarly journals Prognostic Significance of Tumor Location in T2 Gallbladder Cancer: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 10 (15) ◽  
pp. 3317
Author(s):  
Hyun Kang ◽  
Yoo Shin Choi ◽  
Suk-Won Suh ◽  
Geunjoo Choi ◽  
Jae Hyuk Do ◽  
...  
Keyword(s):  
Gallbladder Cancer ◽  
Large Scale ◽  
Treatment Guidelines ◽  
Prognostic Significance ◽  
Tumor Location ◽  
Cochrane Library ◽  
Poor Prognostic Factor ◽  
Simple Cholecystectomy ◽  
Survival Difference ◽  
Extended Cholecystectomy

(1) Background: The AJCC Cancer Staging Manual, Eighth Edition, subdivided T2 GBC into T2a and T2b. However, there still exist a lack of evidence on the prognostic significance of tumor location. The aim of the present study was to examine the existing evidence to determine the prognostic significance of tumor location of T2 gallbladder cancer (GBC) and to evaluate the optimal surgical extent according to tumor location. (2) Methods: We searched for relevant literature published in the electronic databases PubMed, MEDLINE, Web of Science, Cochrane Library, and Embase before September 2020 using search terms related to gallbladder, cancer, and stage. Data were weighted and pooled using random-effects modeling. (3) Results: Seven studies were deemed eligible for inclusion, representing a cohort of 1789 cases of resected T2 GBC. The overall survival for T2b tumor was significantly worse than that for T2a tumor (HR, 2.141; 95% confidence interval (CI), 1.140 to 4.023; I2 = 71.4%; Pchi2 = 0.007). The rate of lymph node metastasis was lower in the T2a group (26.6%) than in the T2b group (36.6%) (OR, 2.164; 95% CI, 1.309 to 3.575). There was no evidence of a survival difference between the patients who underwent extended cholecystectomy and simple cholecystectomy in T2a GBC (OR, 0.802; 95% CI, 0.618 to 1.042) and T2b GBC (OR, 0.820; 95% CI, 0.620 to 1.083). (4) Conclusions: Hepatic side tumor was a significant poor prognostic factor in T2 GBC. Extended cholecystectomy and simple cholecystectomy showed comparable survival outcomes in T2 GBC, and additional large-scale prospective studies are warranted to establish evidence-based treatment guidelines for T2 GBC.

Early Gallbladder Carcinoma: A Single-Center Experience

2006 ◽  
Vol 92 (6) ◽  
pp. 487-490 ◽  
Author(s):  
Vincenzo Cangemi ◽  
Enrico Fiori ◽  
Cristina Picchi ◽  
Alessandro De Cesare ◽  
Roberto Cangemi ◽  
...  
Keyword(s):  
Gallbladder Carcinoma ◽  
Tnm Classification ◽  
Muscularis Propria ◽  
Surgical Approaches ◽  
Term Survival ◽  
Simple Cholecystectomy ◽  
Single Center Experience ◽  
Appropriate Treatment ◽  
Extended Cholecystectomy

Aims and background Controversy continues regarding the best surgical treatment for early gallbladder carcinoma defined as a tumor confined to the mucosa (pT1a) or to the muscularis propria (pT1 b) according to the TNM classification. This study evaluates the effectiveness of different surgical approaches in patients with early gallbladder carcinoma in terms of long-term survival. Materials and methods From 1980 to 2001, 175 patients with gallbladder carcinoma were admitted to our department. Fifteen of them underwent resections for early gallbladder carcinoma: 4 patients for pT1a tumors and 11 patients for pT1b tumors. All patients with pT1a tumors and 8 patients with pT1b tumors underwent simple cholecystectomy. The remaining 3 patients with pT1 b tumors underwent extended cholecystectomy. Results The 5-10 year cumulative survival rate was 100% for patients with pT1a tumors, 37.5% for patients with pT1b tumors who underwent simple cholecystectomy, and 100% for patients with pT1b tumors who underwent extended cholecystectomy. Conclusions Simple cholecystectomy is the appropriate treatment for patients with pT1a tumors, whereas patients with pT1b tumors require an extended cholecystectomy.

Laparoscopic extended cholecystectomy for T3 gallbladder cancer

2017 ◽  
Vol 32 (6) ◽  
pp. 2984-2985 ◽  
Author(s):  
Sungho Kim ◽  
Yoo-Seok Yoon ◽  
Ho-Seong Han ◽  
Jai Young Cho ◽  
YoungRok Choi
Keyword(s):  
Gallbladder Cancer ◽  
Extended Cholecystectomy

scholarly journals Cavernous Hemangioma of the Gallbladder Masquerading as a Carcinoma

2019 ◽  
Vol 13 (1) ◽  
pp. 219-224
Author(s):  
Naotake Funamizu ◽  
Yukio Nakabayashi
Keyword(s):  
Computed Tomography ◽  
Cavernous Hemangioma ◽  
Benign Tumors ◽  
Low Density ◽  
Vascular Endothelial ◽  
Postoperative Course ◽  
Follow Up Study ◽  
Abdominal Computed Tomography ◽  
Extended Cholecystectomy

Cavernous hemangioma arising from the gallbladder is extremely rare. Here, we report a cavernous hemangioma of the gallbladder masquerading as a carcinoma. A 75-year-old man was referred to our institution for a follow-up study after gastrectomy. Abdominal computed tomography revealed that the gallbladder was filled with a low-density mass with calcification of the wall. The patient underwent extended cholecystectomy. Histologically, the tumor consisted of vascular endothelial cellular elements and hematomas. The postoperative course was uneventful without complications. Presently, only 7 cases of cavernous hemangioma of the gallbladder have been previously reported. This case serves as an important reminder to consider benign tumors including cavernous hemangioma when investigating all possible causes of a gallbladder tumor.

scholarly journals Presentation of gallbladder carcinoma and its surgical management

2016 ◽  
Vol 12 (2) ◽  
Author(s):  
Tariq Waqar ◽  
Rasheed Ahmed
Keyword(s):  
Gallbladder Carcinoma ◽  
Economic Status ◽  
Gall Stone ◽  
Stage Iv ◽  
Palliative Surgery ◽  
Etiological Factor ◽  
Female Ratio ◽  
Extended Cholecystectomy ◽  
Surgical Methods ◽  
Operative Findings

Objective:- To study the mode of presentation, age and sex distribution, socio-economic status and evaluation of various surgical methods adopted for treatment of localized and advanced gallbladder carcinoma. Design:- It was a prospective type of study. Place and duration of study: This study was conducted in the Department of Surgery Nishtar Hospital, Multan from January 2004 to June 2005. Patients and methods: Twenty five patients of all ages and both sex were taken from all surgical units. On the basis of history, examination and laboratory investigations they were suspected of having gallbladder cancer. All the patients were operated and were divided into three groups on the basis of operative findings and stage of disease. Results:- There were 4 males and 21 female with a male to female ratio of 1:5. Presenting feature in decreasing order of frequency were; pain in right hypochondrium in 88%, nausea and vomiting in 60%, weight loss in 40%, jaundice in 28%, anorexia in 28%, mass in right hypochondriu m in 24%, pruritis in 20%, fever in 12% and ascites in 4% patients. Preoperative diagnosis of carcinoma of gallbladder was possible in 12 (48%) patients with the help of ultrasound and CT scan but all were of advanced age of disease. Gall stone were the most important etiological factor in 20 (80%) patients, obesity was found in 7 (28%) and chronic typhoid infection in 2 (8%) patients. All patients were operated. Simple cholecystecytomy was done in 4 patients of stage I and II. Extended cholecystectomy done in 6 patients of stage III. Laparotomy and biopsy of the mass and/or palliative surgery for drainage of bile was done in 15 cases of stage IV and V disease. Adenocarcinoma was the most common histological type found in 22 (88%) cases. Conclusion:- Gallstone are the most important etiological factor in gall bladder carcinoma.

scholarly journals Leptomeningeal carcinomatosis from gallbladder cancer after curative resection: A case report and review of literature

2021 ◽  
Author(s):  
MASASHI OKAWA ◽  
JUN KADONO ◽  
IWAO KITAZONO ◽  
SHUNSUKE MOTOI ◽  
KENTARO GEJIMA ◽  
...  
Keyword(s):  
Risk Factors ◽  
Curative Resection ◽  
Fluid Pressure ◽  
Leptomeningeal Carcinomatosis ◽  
Japanese Woman ◽  
Cancer Case ◽  
Extended Cholecystectomy ◽  
Old Japanese ◽  
Impaired Awareness ◽  
The Right

Introduction Only 12 cases of gallbladder (GB) cancer associated with leptomeningeal carcinomatosis (LMC) have been reported so far. Herein, we report the first known case of LMC originating from GB cancer after curative resection and discuss the risk factors of LMC associated with GB cancer. Case Presentation An 85-year-old Japanese woman presented with vomiting and impaired awareness 2 years after curative extended cholecystectomy for GB cancer . Computed tomography showed hydronephrosis of the right kidney and ureteral thickening. Magnetic resonance imaging revealed areas of hyperintense reflecting lesions along the cerebral sulci, suggesting meningitis. A spinal tap showed an elevated cerebrospinal fluid pressure of > 270 mmH 2 O, and cytological examination of the spinal fluid revealed the presence of adenocarcinoma cells. The patient was diagnosed with retroperitoneal metastasis and LMC originating from GB cancer. The patient was given palliative care and died 4 weeks after the onset of symptoms. Conclusion The findings of this study show that LMC could occur even after curative resection of GB cancer and should be considered when patients present with neurological symptoms. Retroperitoneal metastases and poorly differentiated tumors are possible risk factors of LMC originating from GB cancer.

scholarly journals Survival Benefits of Simple Versus Extended Cholecystectomy and Lymphadenectomy for Patients With T2 Gallbladder Cancer: A Propensity-Matched Population-Based Study (2010 to 2015)

2021 ◽  
Vol 11 ◽  
Author(s):  
Wei Zhang ◽  
Zhangkan Huang ◽  
Wen-er Wang ◽  
Xu Che
Keyword(s):  
Overall Survival ◽  
Propensity Score ◽  
Gallbladder Cancer ◽  
Propensity Score Matching ◽  
Survival Benefit ◽  
Confounding Factors ◽  
Simple Cholecystectomy ◽  
Regional Lymphadenectomy ◽  
Extended Cholecystectomy ◽  
Significant Survival

ObjectiveThis article aims to evaluate the survival benefits of simple cholecystectomy, extended cholecystectomy, as well as scope regional lymphadenectomy for T2 gallbladder cancer (GBC) patients.MethodsWe identified eligible patients from the Surveillance, Epidemiology, and End Results database. The confounding factors were controlled via propensity score matching. The log-rank test was utilized to compare overall survival. The multivariate Cox regression was then used to determine risk factors.ResultsOverall, data from 1,009 patients were obtained. The median overall survival (OS) of 915 patients that underwent simple cholecystectomy was 15 months; the median OS of 94 patients that underwent extended cholecystectomy was 17 months. There were no significant differences before and after propensity score matching (p = 0.542 and p = 0.258). The patients who received regional lymphadenectomy did show significant survival benefit, compared to those who did not receive regional lymphadenectomy. Furthermore, this benefit is observed in the N0 stage, but not observed in the N1 stage. In addition, the OS of patients who received lymphadenectomy for four or more regions was significantly better than those who received one to three regions lymphadenectomy. Age, the scope of regional lymphadenectomy, N stage, and tumor size were identified as prognostic factors.ConclusionsExtended cholecystectomy was not observed to significantly improve postoperative prognosis of patients with T2 GBC. However, there was a significant survival benefit shown for those with regional lymphadenectomy, particularly for patients with negative lymph nodes. Future studies on the control of potential confounding factors and longer follow-ups are still needed.

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