scholarly journals Hubungan Kadar Timbal Dalam Darah Dengan Tekanan Darah Pada Tenaga Kerja Di Karoseri Semarang

2016 ◽  
Vol 15 (1) ◽  
pp. 14
Author(s):  
Mutasir Mutasir ◽  
Onny Setiani ◽  
Sulistiyani Sulistiyani
Keyword(s):  
Blood Pressure ◽  
Lead Exposure ◽  
Toxic Metal ◽  
Blood Lead ◽  
Threshold Value ◽  
Blood Lead Levels ◽  
Cross Sectional ◽  
Lead Levels ◽  
Preliminary Study ◽  
Ppm Level

Background: Lead is a toxic metal that can be contained in paint as a source of lead exposure in the air so significantly associated with blood lead levels (BLL). Statistically there is a significant association between BLL and blood pressure (BP). Preliminary study found that 10 workers of Carroseri Semarang found that 8 people (80%) had BLL above the threshold value, 7 people (70%) had a systolic blood pressure (SBP) above the limit normal and 8 people (80%) had diastolic blood pressure (DBP) at the upper limit of normal.Objective: This study aimed to determine the association between BLL and BP workers of Carroseri Semarang.Methods: It was an observational study with cross sectional approach. The population of this research was workers of Carroseri Semarang with a sample size of 34 people. Data collected by examining the levels of lead in paint, inspection level of lead in the air, checking blood lead levels and blood pressure checks.Results: This study showed the average level of lead in the paint measured was 59.39 ppm, level of lead in the air 0.002 ppm, BLL 28.97 mg/dL, SBP 122.76 mmHg and DBP 79.06 mmHg.Conclusion: All types of paint used in Carroseri Semarang contain lead under TLVs 600 ppm, the ambient workspace containing air lead levels below TLVs 0.05 ppm, the entire workforce part painting has undergone blood lead exposure >5μg/dL, there is no association between BLL and SBP (p=0.465) and there a association between BLL and DBP (p =0.030).

scholarly journals Blood lead level and risk of hypertension in the United States National Health and Nutrition Examination Survey 1999–2016

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Man Fung Tsoi ◽  
Chris Wai Hang Lo ◽  
Tommy Tsang Cheung ◽  
Bernard Man Yung Cheung
Keyword(s):  
Blood Pressure ◽  
Lead Exposure ◽  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
The United States ◽  
Study Data ◽  
Blood Lead Levels ◽  
Environmental Lead ◽  
Lead Levels

AbstractLead is a heavy metal without a biological role. High level of lead exposure is known to be associated with hypertension, but the risk at low levels of exposure is uncertain. In this study, data from US NHANES 1999–2016 were analyzed. Adults with blood lead and blood pressure measurements, or self-reported hypertension diagnosis, were included. If not already diagnosed, hypertension was defined according to the AHA/ACC 2017 hypertension guideline. Results were analyzed using R statistics version 3.5.1 with sample weight adjustment. Logistic regression was used to study the association between blood lead level and hypertension. Odds ratio (OR) and 95% confidence interval (95% CI) were estimated. Altogether, 39,477 participants were included. Every doubling in blood lead level was associated with hypertension (OR [95%CI] 1.45 [1.40–1.50]), which remained significant after adjusting for demographics. Using quartile 1 as reference, higher blood lead levels were associated with increased adjusted odds of hypertension (Quartile 4 vs. Quartile 1: 1.22 [1.09–1.36]; Quartile 3 vs. Quartile 1: 1.15 [1.04–1.28]; Quartile 2 vs. Quartile 1: 1.14 [1.05–1.25]). In conclusion, blood lead level is associated with hypertension in the general population with blood lead levels below 5 µg/dL. Our findings suggest that reducing present levels of environmental lead exposure may bring cardiovascular benefits by reducing blood pressure.

Low-Level Lead Exposure and Blood Lead Levels in Children: A Cross-Sectional Survey

2001 ◽  
Vol 56 (6) ◽  
pp. 501-505 ◽  
Author(s):  
Aysha Habib Khan ◽  
Amanullah Khan ◽  
Farooq Ghani ◽  
Muhammad Khurshid
Keyword(s):  
Lead Exposure ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Low Level ◽  
Lead Levels

scholarly journals Assessment of a Screening Questionnaire to Identify Exposure to Lead in Pregnant Women

2020 ◽  
Vol 17 (24) ◽  
pp. 9220
Author(s):  
Eléna Coiplet ◽  
Marine Freuchet ◽  
Claire Sunyach ◽  
Julien Mancini ◽  
Jeanne Perrin ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Lead Exposure ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Cross Sectional ◽  
Lead Levels ◽  
Risk Of Exposure ◽  
Exposure During Pregnancy ◽  
Systematic Identification

Lead readily crosses the placenta and displays adverse effects on birth outcomes and neurodevelopment. Systematic identification of the risk of exposure during pregnancy is essential but rarely performed, probably due to hospital staff’s workload and their lack of awareness. We aimed to evaluate the relevance of a questionnaire to screen pregnant women for lead exposure. A cross-sectional, multicentre study was carried out on a population of 792 pregnant women from February 2018 to May 2020. A total of 596 women had a blood lead test: 68.5% had blood lead levels below 10 μg/L. The estimated prevalence above 25 µg/L was 4% (95% confidence interval (CI) [2.6–5.9]) and 1.3% had levels above 50 µg/L (95% CI [0.6–2.6]). Multivariate analysis showed that three risk factors significantly increased the probability of blood lead levels above 25 µg/L: the use of traditional cosmetics (adjusted odds ratio [aOR]: 3.90; 95% CI [1.65–9.21]; p = 0.002), degraded old housing (aOR: 2.67; 95% CI [1.19–6.038]; p = 0.018), and (marginally) eating bread more than twice a day (aOR: 2.40; 95% CI [0.96–6.11]; p = 0.060). Our study reveals that a three-question tool can be used to quickly screen for the risk of lead exposure in our population and to trigger lead blood tests and special vigilance during pregnancy follow-up.

scholarly journals Blood Lead Levels in Pregnant Women and the Source of Exposure in Northern Coastal Area of Brebes Regency

2018 ◽  
Vol 1 (1) ◽  
pp. 6-12
Author(s):  
Nova Amalia Sakina ◽  
Suhartono Suhartono ◽  
Nikie Astorina Yunita Dewanti
Keyword(s):  
Pregnant Women ◽  
Lead Exposure ◽  
Passive Smoking ◽  
Blood Lead ◽  
Quality Standard ◽  
Cross Sectional Study ◽  
Blood Lead Levels ◽  
Agricultural Activity ◽  
Cross Sectional ◽  
Lead Levels

Background: Lead has no advantage for health, pregnant women are vulnerable to lead exposure. Blood Lead Levels (BLLs) in pregnant women that exceed the quality standard in accordance with Center for Disease Control (CDC) (>5 μg/dL) can encounter spontaneous miscarriage and fatigue easily during pregnancy, BLLs in pregnant women < 10 μg/dL can induce health problem during pregnancy such as hypertension, preeclampsia, and eclampsia which is the cause of mortality in pregnant women and high maternal mortality. The aim of study to measure BBLs and the source of exposure.Methods: Pregnant women in 2nd and 3rd trimester were recruited in 4 Subdistricts. Cross sectional study is used with 86 pregnant women located in Wanasari Subdistrict, Bulakamba Subdistrict, Losari Subdistrict and Tanjung Subdistrict with purposive sampling method. BLLs during pregnancy were determined by Atomic Adsorpiton Spectrometer.Results: The results shows that mean of BLLs in pregnant women in this study were 42.437 + 19.758 μg/dL. The source of lead exposure are the habit of consuming seafood (44.2%), wrapping food using newspaper (80.2%), being involve in agricultural activity (37.2%), and passive smoking (70.9%).Conclusions: To recapitulate, BBLs in pregnant women in the northern area of Brebes Regency have exceeded the standard set by the CDC of 5 μg/dL. The dominant source of lead exposure are the habit of wrapping food using newspaper and passive smoking.

scholarly journals Missile-related Lead Exposure and Blood Pressure in Patients with Retained Pellets in the Craniomaxillofacial Region

2018 ◽  
Vol 12 (6) ◽  
pp. 7-12
Author(s):  
Ekaniyere Benlance Edetanlen ◽  
◽  
Ozoemene Ndubuisi Obuekwe ◽  
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Lead Exposure ◽  
Predictor Variable ◽  
Positive Association ◽  
Blood Lead ◽  
Outcome Variable ◽  
Blood Lead Levels ◽  
P Value ◽  
Lead Levels

Background: Environmental and occupational lead exposures are known to cause an elevated blood pressure but can this concept be applied to missile-related lead exposure? Methods: We implemented a controlled, cohort study design to examine study samples with long-standing missiles in craniomaxillofacial region using atomic absorption spectrophotometry and standard sphygmomanometry to measure the blood lead levels and blood pressure respectively. The predictor variable was blood lead levels and the outcome variable were blood pressure. Other variables were age, number of pellets, and duration of retention. Descriptive, bivariate and multivariate statistics were computed and the P-value was set at 0.05. Results: There was a significant, strong and positive association seen between diastolic blood pressure (r = 0.34;P< 0.001) unlike systolic blood pressure that showed an insignificant, weak and negative associations with blood lead levels(r = - 0.01, P = 0.82). Binary logistic regression showed that blood lead levels, though less significant, (OR= 1.24, P = 0.01, 95%CI = 1.04-1.42) had a higher likelihood to cause hypertension than the age of the patients (OR = 1.03, 95%CI=1.01-1.04, 0.003). Conclusion: The results of this study suggest an association between missiles-related lead exposure and the diastolic blood pressure.

scholarly journals Blood Pressure and Oxidative Stress among U.S. Adults Exposed to Lead in Military Environments—A Preliminary Study

Diseases ◽  
2018 ◽  
Vol 6 (4) ◽  
pp. 97 ◽  
Author(s):  
Emmanuel Obeng-Gyasi ◽  
Barnabas Obeng-Gyasi
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Lead Exposure ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Gamma Glutamyl Transferase ◽  
Clinical Markers ◽  
Cross Sectional ◽  
Lead Levels ◽  
Glutamyl Transferase

In this cross-sectional study, lead exposure among those with a history in military environments was examined. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) are clinical markers of blood pressure, while gamma-glutamyl transferase (GGT) is a marker of oxidative stress. These markers and their effects on those exposed to military environments were explored using National Health and Nutrition Examination Survey (NHANES) data from 2009 to 2016. Mean SBP and GGT were significantly elevated in those exposed to military environments, with a moderately significant association existing between blood lead levels (BLLs) and SBP. More attention must be given to lead exposure in military environments to mitigate the risk of exposure.

scholarly journals PENINGKATAN KADAR TIMBAL DARAH DAN MUNCULNYA PERILAKU ANTISOSIAL PENGRAJIN KUNINGAN

2015 ◽  
Vol 11 (1) ◽  
pp. 144
Author(s):  
Aditya Marianti ◽  
Anies Anies ◽  
Henna Rya Sunoko Abdurachim
Keyword(s):  
Antisocial Behavior ◽  
Blood Lead ◽  
Threshold Value ◽  
Cross Sectional Study ◽  
Lead Contamination ◽  
School Level ◽  
Blood Lead Levels ◽  
Cross Sectional ◽  
Lead Levels ◽  
Chronic Lead Exposure

<p>Penelitian ini bertujuan mengkaji pengaruh peningkatan kadar timbal (Pb) darah terhadap munculnya perilaku antisosial pada pengrajin kuningan. Disain penelitian  observasional analitik dengan studi cross sectional. Sampel terdiri dari 55 orang pengrajin kuni ngan, dengan kriteria inklusi pria atau wanita, minimal 17 tahun, telah bekerja di industri kuningan minimal 2 tahun, pendidikan minimal pernah SD. Hasil penelitian menunjukkan telah terjadi kontaminasi Pb di lingkungan kerja industri kuningan. Kadar Pb darah pengrajin yang melebihi  nilai ambang batas40µg/dl mencapai 80%. Perilaku antisosial terukur masuk kategori sedang dan rendah. Terdapat hubungan linier antara kadar Pb darah dan perilaku antisosial dengan R2 0,353. Simpulan pajanan kronik Pb di lingku- ngan kerja industri kuningan menyebabkan peningkatan kadar Pb darah pengrajin dan berkontribusi memicu  munculnya perilaku antisosial.</p><p> </p><p><em>This study aimed to examine the effect of increased Blood Lead Levels (BLL) results of the emergence of antisocial behavior in brass craftsmen. The research designs used the analytic observational with cross sectional study. The sample consisted of 55 brass craftsmen, male or female a minimum of 17 years old, has worked in the brass industry at least for 2 years, and at least has a degree in the elementary school level. The results showed that there has been a lead contamination in the environment of brass industry. BLL that exceed the threshold value (40 μg/dl) reached 80%. The antisocial behavior measured was in the category of medium and low. There was a linear relationship between BLL and antisocial behavior with R2 0.353. In conclusion, chronic lead exposure to the brass industry environment led to an increase to blood lead levels BLL  in craftsmen contributed in the appearance of antisocial behavior.</em></p>

scholarly journals The correlation between uremic pruritus and blood lead levels in prevalent hemodialysis patients and its relation to the severity of pruritus using visual analog score

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Sahar Mahmoud Shawky ◽  
Reeham Abdel Aziz Abdel Hamid ◽  
Lina Essam Khedr
Keyword(s):  
Blood Lead ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Visual Analog Score ◽  
Blood Lead Levels ◽  
Cross Sectional ◽  
Uremic Pruritus ◽  
Significant Difference ◽  
Lead Levels ◽  
Group 2

Abstract Background Pruritus is a common and often distressing symptom in patients with chronic kidney disease. Though the pathogenesis of uremic pruritus remains poorly understood, systemic inflammation has presented itself as one of the possible explanations. High blood lead levels (BLLs) have been noted to be associated with inflammation and poor nutritional status in hemodialysis patients. Our aim is to study the relation between blood lead levels and uremic pruritus. This is a cross-sectional study that enrolled 50 patients; all were on regular hemodialysis 3 times per week for at least 6 months. Patients were divided into 2 groups, group 1 (n =10) with no pruritus and group 2 (n=40) with varying degrees of pruritus. Group 2 was further divided according to intensity of pruritus by visual analog score (VAS) into mild (n=10), moderate (n=20), and severe pruritus (n=10). Results There was a significant difference in serum lead levels and ferritin levels between groups 1 and 2 (p value < 0.01 and < 0.05, respectively). There was a statistically significant difference in serum lead levels in the groups with varying intensity of pruritus, having higher serum lead levels in patients who exhibited severe pruritus (p value < 0.005) Moreover, a statistically significant relation between elevated blood lead levels and the duration of dialysis was observed in this study. Conclusion Uremic pruritus is a multi-factorial phenomenon, and our study showed that blood lead levels in hemodialysis patients might be associated with increased intensity of pruritus.

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