scholarly journals The EMBnet International Conference 2020: Bioinformatics Approaches to Precision Research

2021 ◽  
Vol 26 (A) ◽  
pp. e1006
Author(s):  
Domenica D'Elia ◽  
Cesar Bonavides-Martinez ◽  
Erik Bongcam-Rudloff ◽  
Emiliano Barreto-Hernandez ◽  
Aspasia Efthimiadou ◽  
...  

In this paper, we first summarise the 2020 International Conference of EMBnet (The Global Bioinformatics Network) on “Bioinformatics Approaches to Precision  Research”, held on 23th-24th September 2020,  and then briefly introduce the main topics and contributions presented at the Conference and published in this supplement issue. The Conference’s main aim was to share the knowledge and scientific achievements of EMBnet members to prompt the cross-fertilisation of ideas and collaborations.  The title reflects the type of contributions presented (20 in total), covering a wide range of cutting-edge research topics for which advanced bioinformatics methods and precision approaches are essential, and training in Bioinformatics. As for many other organisations, 2020 was the first year that the EMBnet Annual General Meeting was not in presence but ran on a virtual meeting platform because of the pandemic’s travel restrictions to moves. If this situation represented a limitation to our social activities, it allowed us to offer the possibility to attend the Conference to a larger number of researchers (i.e., 190 from 38 different countries). Among all registered people,  148 were following the conference presentations on both days. Under the authors’ permission, presentations were recorded and are available at the EMBnet Conference 2020 playlist on YouTube (https://youtube.com/playlist?list=PLVP2771lOozCHAOgVXBdqPW3oclEmzNIA), whereas the programme is available at the EMBnet Conference 2020 Google Drive folder (https://drive.google.com/file/d/1wWqp_I5vf-1GUlKmbCUq45EDQ9LfbrpC/view)

2020 ◽  
Vol 13 (S11) ◽  
Author(s):  
Xinghua Shi ◽  
Zhongming Zhao ◽  
Kai Wang ◽  
Li Shen

AbstractThis editorial summarizes eight research articles included in this supplement issue for the 2020 International Conference on Intelligent Biology and Medicine (ICIBM 2020) conference, that was held on August 9-10, 2020 (virtual conference), with a topic on data-driven analytics in biomedical genomics. These articles cover a wide range of topics in medical genomics that focus on integrative analysis of genomics data together with other types of data toward understanding complex human diseases, including cancer. With the growing importance of data analytics in biomedical science, we expect this collection of research articles provides scientific discussions in this direction.


Author(s):  
Alan Kelly

What is scientific research? It is the process by which we learn about the world. For this research to have an impact, and positively contribute to society, it needs to be communicated to those who need to understand its outcomes and significance for them. Any piece of research is not complete until it has been recorded and passed on to those who need to know about it. So, good communication skills are a key attribute for researchers, and scientists today need to be able to communicate through a wide range of media, from formal scientific papers to presentations and social media, and to a range of audiences, from expert peers to stakeholders to the general public. In this book, the goals and nature of scientific communication are explored, from the history of scientific publication; through the stages of how papers are written, evaluated, and published; to what happens after publication, using examples from landmark historical papers. In addition, ethical issues relating to publication, and the damage caused by cases of fabrication and falsification, are explored. Other forms of scientific communication such as conference presentations are also considered, with a particular focus on presenting and writing for nonspecialist audiences, the media, and other stakeholders. Overall, this book provides a broad overview of the whole range of scientific communication and should be of interest to researchers and also those more broadly interested in the process how what scientists do every day translates into outcomes that contribute to society.


Proceedings ◽  
2021 ◽  
Vol 77 (1) ◽  
pp. 8
Author(s):  
Garth Davies ◽  
Madison Reid

Many existing programs for countering violent extremism focus on either end of the radicalization spectrum. On one hand are prevention programs aimed at deterring individuals from starting down the path to violent extremism. On the other hand are disengagement/de-radicalization programs designed for assisting individuals who have been fully radicalized. Conspicuously absent are programs for those who fall in-between, into what might be referred to as the pre-criminal space: individuals who have begun to exhibit signs of radicalization, but for whom radicalization is not yet complete. The British Columbia Shift (BC Shift) initiative was created to assist individuals determined to be in this pre-criminal space; that is, those deemed to be in danger of radicalizing. The goal of BC Shift is to stop individuals from traveling further down the path of radicalization, and, ideally, to turn individuals away from the path. BC Shift operates as a navigational model, connecting at-risk individuals with services and supports in the community. BC Shift is a government initiative supported by the Canada Centre for Community Engagement and Prevention of Violence. It is a civilian organization that partners very closely with, but is separate from, law enforcement. In addition to its primary CRVE mandate, BC Shift has rapidly evolved and expanded into several other responsibilities, including coordination on national CVE standards; liaising with other CVE programs across Canada; maintaining stakeholder relationships; and helping create capacity through dialog and training. Although the program only began accepting referrals in 2019, its operation has already revealed many important lessons for CRVE programs. First, it is critically important to have the right people in the room. There has to be buy-in from the highest levels of partner agencies and stakeholders, particularly early on. Second, programs of this sort should leverage existing resources wherever possible. BC Shift has been lucky enough to coordinate with situation tables, such as the CHART program in Surrey. There are already many organizations doing excellent work in their respective communities; it is very helpful to plug into those resources. Third, even though BC Shift operates as a navigational hub, it has benefitted greatly from having a social worker as part of the team. This skill set is important in helping referred individuals feel comfortable with the process of accessing services and supports. Finally, marketing matters! CRVE programs such as BC Shift have to navigate a complex reality. The very concept of violent extremism is disconcerting to a lot of people in the community; these fears have to be addressed, and difficulties related to differences in perspective and language have to be overcome. BC Shift’s first year-and-a-half of operation has also highlighted several issues that have not yet been satisfactorily resolved. There is, for example, the “low hanging fruit” problem; agencies are typically referring less severe cases. Trying to get agencies to refer more serious cases has proved challenging. We hope that, by outlining these lessons and issues, this presentation proves to be useful to other CRVE initiatives.


Author(s):  
R. Vinodh Kumar ◽  
M. Vakkil

The study was conducted to identify the most difficult topic in elementary teacher education first-year social science curriculum as perceived by the student-teachers by using survey research design. The study also investigated the underlying reasons responsible for the student-teachers' difficulties in learning different topics. 218 student-teachers were selected using convenience sampling technique from five District Institutes of Education and Training (DIET), in Tamil Nadu State (India) for the study. The instrument used for data collection was a checklist designed by the researchers to elicit information from the student-teachers. The data collected were analysed using frequencies and percentages. The results showed that the topic namely, 'Reading the Globe, Maps and Atlas' was perceived as the most difficult topic in social science curriculum. The results also showed that teaching the topic without using the maps, lack of previous knowledge about the maps, the existence of vague concepts, heavy content load, and lack of interest and motivation to learn map concepts were the main reasons responsible for the student-teachers' difficulties in learning the topic.


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Bart M Demaerschalk ◽  
Robert D Brown ◽  
Virginia J Howard ◽  
MeeLee Tom ◽  
Mary E Longbottom ◽  
...  

Introduction: Careful selection and timely activation of clinical sites in multicenter clinical trials is critical for successful enrollment, subject safety, and generalizability of results. Methods: In the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2), a multidisciplinary Site Selection Committee evaluated applicants referred via participation in CREST, CREST principal investigators (PIs) and other investigators, StrokeNet and industry partners. Data for consideration included performance metrics in CREST and other carotid trials and a site selection questionnaire containing information on the investigators as well as quantitative data on carotid procedures performed. Any FDA warning letters were reviewed. Results: The Committee met bi-weekly for 36 months (n=64 meetings). Applications from 176 sites between March 2014 and July 2016 were evaluated: 153 were approved, 7 are under Committee review, 5 were approved but withdrew, 5 were placed on a waiting list, and 6 were rejected. One-hundred-four sites have completed the regulatory and training requirements to randomize: 51 (49%) academic medical centers, 31 (30%) private hospital-based centers, 16 (15%) private office-based practices, and 6 (6%) Veterans Administration medical centers. The mean times from application-to- approval was 5.2 weeks (interquartile range, 1.9, 6.2), and from approval-to-randomization status was 46.7 weeks (interquartile range, 35.4, 51.7). Specialties of the 104 site PIs are vascular surgery for 35 (33.7%), cardiology for 30 (28.8%), neurology for 25 (24%), neurosurgery for 8 (7.7%), interventional radiology for 4 (3.8%), and interventional neuroradiology for 2 (1.9%). Conclusions: Careful site selection is time-consuming for prospective sites and for trial leadership. Times from application-to-site-approval were modest (mean = 5.2 weeks), in contrast to the times for completing regulatory and training requirements (mean = 46.7 weeks). However, subject enrollment by teams from a wide range of medical centers led by a multi-disciplinary cohort of PIs will promote the generalizability of trial results.


2008 ◽  
Vol 5 (2) ◽  
pp. 535-547 ◽  
Author(s):  
A. Olsen ◽  
K. R. Brown ◽  
M. Chierici ◽  
T. Johannessen ◽  
C. Neill

Abstract. We present the first year-long subpolar trans-Atlantic set of surface seawater CO2 fugacity (fCO2sw) data. The data were obtained aboard the MV Nuka Arctica in 2005 and provide a quasi-continuous picture of the fCO2sw variability between Denmark and Greenland. Complementary real-time high-resolution data of surface chlorophyll-a (chl-a) concentrations and mixed layer depth (MLD) estimates have been collocated with the fCO2sw data. Off-shelf fCO2sw data exhibit a pronounced seasonal cycle. In winter, surface waters are saturated to slightly supersaturated over a wide range of temperatures. Through spring and summer, fCO2sw decreases by approximately 60 μatm, due to biological carbon consumption, which is not fully counteracted by the fCO2sw increase due to summer warming. The changes are synchronous with changes in chl-a concentrations and MLD, both of which are exponentially correlated with fCO2sw in off-shelf regions.


Author(s):  
Michael Gessler ◽  
Sandra Bohlinger ◽  
Olga Zlatkin-Troitschanskaia

The seven articles in this special issue represent a wide range of international comparative and review studies by international research teams from China, Germany, India, Russia, Switzerland and Mexico. The presented projects are part of the national program "Research on the Internationalisation of Vocational Education and Training", funded by the German Federal Ministry of Education and Research (BMBF).  An adapted version of Urie Bronfenbrenner’s ecological systems theory forms the conceptual framework of the special issue. The four system levels (micro, meso, exo and macro) are addressed by one article each. The article on the microsystem level focuses on the intended and implemented curricula in a cross-country comparison of China and Russia. The article on the mesosystem level aims at the development of a quality management model for vocational education and training (VET) institutions in India. At the exolevel, the regional structures of the education and employment systems in Mexico, particularly the cooperation between schools and companies in the hotel industry, are investigated. At the macrosystem level, the social representation of non-academic labour in Mexico is examined in terms of cultural artefacts. Furthermore, three overarching review studies systematise relevant research developments and approaches. The topics of the three review studies are European VET policy, transfer of VET and VET research. The scope ranges from the development of a comparative research tool to a summary analysis of over 5,000 individual publications. Given the broad scope and heterogeneity of the findings, a summative conclusion would hardly be appropriate. Nevertheless, with regard to the model of the ‘triadic conception of purposes in comparative VET research’ that represents a heuristic for describing the purposes of international VET research, we conclude with an emphasis on a need of more criticality. In this context, one finding can be pointed out as an example: One review study found that most studies (here, with reference to VET transfer) refer to the recipient country without a comparative perspective. Thus, there is a clear demand for more comparative research following a critical-reflective approach. 


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