scholarly journals An actuated larynx phantom for pre-clinical evaluation of droplet-based reflex-stimulating laryngoscopes

2019 ◽  
Vol 5 (1) ◽  
pp. 137-140
Author(s):  
Jacob Friedemann Fast ◽  
Jiazhen He ◽  
Tobias Ortmaier ◽  
Michael Jungheim ◽  
Martin Ptok ◽  
...  

AbstractThe laryngeal adductor reflex (LAR) is an important protective function of the larynx to prevent aspiration and potentially fatal aspiration pneumonia by rapidly closing the glottis. Recently, a novel method for targeted stimulation and evaluation of the LAR has been proposed to enable non-invasive and reproducible LAR performance grading and to extend the understanding of this reflexive mechanism. The method relies on the laryngoscopically controlled application of accelerated water droplets in association with a high-speed camera system for LAR stimulation site and reflex onset latency identification. Prototype laryngoscopes destined for this method require validation prior to extensive clinical trials. Furthermore, demonstrations using a realistic phantom could increase patient compliance in future clinical settings. For these purposes, a model of the human larynx including vocal fold actuation for LAR simulation was developed in this work. The combination of image processing based on a custom algorithm and individual motorization of each vocal fold enables spatio-temporal droplet impact detection and controlled vocal fold adduction. To simulate different LAR pathologies, the current implementation allows to individually adjust the reflex onset latency of the ipsi- and contralateral vocal fold with respect to the automatically detected impact location of the droplet as well as the maximum adduction angle of each vocal fold. An experimental study of the temporal offset between desired and observed LAR onset latency due to image processing was performed for three average droplet masses based on highspeed recordings of the phantom. Median offsets of 100, 120 and 128 ms were found (n=16). This offset most likely has a multifactorial cause (image processing delay, inertia of the mechanical components, droplet motion). The observed offset increased with increasing droplet mass, as fluid oscillations after impact may have been detected as motion. In future work, alternative methods for droplet impact detection could be explored and the observed offset could be used for compensation of this undesirable delay.

2014 ◽  
Vol 28 (6) ◽  
pp. 681-687 ◽  
Author(s):  
Stellan Hertegård ◽  
Hans Larsson

1995 ◽  
Vol 2 (2) ◽  
pp. 161-172 ◽  
Author(s):  
Kohtaro Ohba ◽  
Hitoshi Soyama ◽  
Sho Takeda ◽  
Hikaru Inooka ◽  
Risaburo Oba
Keyword(s):  

2019 ◽  
Vol 13 (2) ◽  
pp. 174-180
Author(s):  
Poonam Sharma ◽  
Ashwani Kumar Dubey ◽  
Ayush Goyal

Background: With the growing demand of image processing and the use of Digital Signal Processors (DSP), the efficiency of the Multipliers and Accumulators has become a bottleneck to get through. We revised a few patents on an Application Specific Instruction Set Processor (ASIP), where the design considerations are proposed for application-specific computing in an efficient way to enhance the throughput. Objective: The study aims to develop and analyze a computationally efficient method to optimize the speed performance of MAC. Methods: The work presented here proposes the design of an Application Specific Instruction Set Processor, exploiting a Multiplier Accumulator integrated as the dedicated hardware. This MAC is optimized for high-speed performance and is the application-specific part of the processor; here it can be the DSP block of an image processor while a 16-bit Reduced Instruction Set Computer (RISC) processor core gives the flexibility to the design for any computing. The design was emulated on a Xilinx Field Programmable Gate Array (FPGA) and tested for various real-time computing. Results: The synthesis of the hardware logic on FPGA tools gave the operating frequencies of the legacy methods and the proposed method, the simulation of the logic verified the functionality. Conclusion: With the proposed method, a significant improvement of 16% increase in throughput has been observed for 256 steps iterations of multiplier and accumulators on an 8-bit sample data. Such an improvement can help in reducing the computation time in many digital signal processing applications where multiplication and addition are done iteratively.


2021 ◽  
Vol 11 (4) ◽  
pp. 1817
Author(s):  
Zheng Li ◽  
Azure Wilson ◽  
Lea Sayce ◽  
Amit Avhad ◽  
Bernard Rousseau ◽  
...  

We have developed a novel surgical/computational model for the investigation of unilat-eral vocal fold paralysis (UVFP) which will be used to inform future in silico approaches to improve surgical outcomes in type I thyroplasty. Healthy phonation (HP) was achieved using cricothyroid suture approximation on both sides of the larynx to generate symmetrical vocal fold closure. Following high-speed videoendoscopy (HSV) capture, sutures on the right side of the larynx were removed, partially releasing tension unilaterally and generating asymmetric vocal fold closure characteristic of UVFP (sUVFP condition). HSV revealed symmetric vibration in HP, while in sUVFP the sutured side demonstrated a higher frequency (10–11%). For the computational model, ex vivo magnetic resonance imaging (MRI) scans were captured at three configurations: non-approximated (NA), HP, and sUVFP. A finite-element method (FEM) model was built, in which cartilage displacements from the MRI images were used to prescribe the adduction, and the vocal fold deformation was simulated before the eigenmode calculation. The results showed that the frequency comparison between the two sides was consistent with observations from HSV. This alignment between the surgical and computational models supports the future application of these methods for the investigation of treatment for UVFP.


2014 ◽  
Vol 1048 ◽  
pp. 173-177 ◽  
Author(s):  
Ying Mei Wang ◽  
Yan Mei Li ◽  
Wan Yue Hu

Fabric shape style is one of the most important conditions in textile appearance evaluation, and also the main factor influences customer purchasing psychology. At first, the previous fabric shape style evaluation methods are classified and summarized, measurement and evaluation method discussed from tactic and dynamic aspects. Then, companied with computer vision principle, a non-contact method for measuring fabric shape style was put forward. In this method, two high-speed CCD cameras were used to capture fabric movement dynamically, fabric sequences image were obtained in this process. Used the image processing technology include pretreatment and feature point matching to get 3D motion parameters, it can provide data supports for shape style evaluation.


2017 ◽  
Vol 09 (05) ◽  
pp. 1750064 ◽  
Author(s):  
A. Van Hirtum ◽  
X. Pelorson

Experiments on mechanical deformable vocal folds replicas are important in physical studies of human voice production to understand the underlying fluid–structure interaction. At current date, most experiments are performed for constant initial conditions with respect to structural as well as geometrical features. Varying those conditions requires manual intervention, which might affect reproducibility and hence the quality of experimental results. In this work, a setup is described which allows setting elastic and geometrical initial conditions in an automated way for a deformable vocal fold replica. High-speed imaging is integrated in the setup in order to decorrelate elastic and geometrical features. This way, reproducible, accurate and systematic measurements can be performed for prescribed initial conditions of glottal area, mean upstream pressure and vocal fold elasticity. Moreover, quantification of geometrical features during auto-oscillation is shown to contribute to the experimental characterization and understanding.


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