scholarly journals Automated Robust Interpretation of Intraoperative Electrophysiological Signals – A Bayesian Deep Learning Approach

2021 ◽  
Vol 7 (2) ◽  
pp. 69-72
Author(s):  
Tobias Kortus ◽  
Thilo Krüger ◽  
Gabriele Gühring ◽  
Kornelius Lente

Abstract Intraoperative neurophysiological monitoring (IONM) is an essential tool during numerous surgical interventions to assess and monitor the functional integrity of neural structures at risk. A reliable signal interpretation is of importance to support medical staff by reducing manual evaluation. Deep learning (DL) techniques proved to be a robust tool for the analysis of neurophysiological data. The large amount of required manually labeled data as well as the lack of interpretability of the results however often limit the use of DL in medical scenarios. A possible way to tackle these obstacles is the utilization of Bayesian deep learning (BDL) methods. The modelling of uncertainties in the network parameters and the thereby possible quantification of predictive uncertainties allows both the identification of potential erroneous predictions as well as the targeted selection of informative signals in the context of active learning. To evaluate the applicability of BDL for the analysis of electrophysiological data as well as to increase the training efficiency by active learning, we implemented a multi-task Bayesian Convolutional Neural Network (BCNN) for the simultaneous classification of action potentials and the assessment of relevant signal characteristics (latency, maximum, minimum). We compare the results for electromyographical signals (EMG), containing in total approximately twelve thousand signals from 34 patients, with both a traditional non-Bayesian single-task and multi-task CNN. For all models, including the BCNN, we could achieve similar performances with detection rates over 97% accuracy. Further, we could improve training efficiency of the BCNN using pool-based active learning and therefore significantly reduce the required amount of manual labeling. The evaluated predictive uncertainties of the BCNN prove useful both for the efficient selection of informative signals in the context of active learning as well as the interpretation of the predictive posterior distribution and therefore trustworthiness of the classifications.

2020 ◽  
Vol 15 ◽  
Author(s):  
Deeksha Saxena ◽  
Mohammed Haris Siddiqui ◽  
Rajnish Kumar

Background: Deep learning (DL) is an Artificial neural network-driven framework with multiple levels of representation for which non-linear modules combined in such a way that the levels of representation can be enhanced from lower to a much abstract level. Though DL is used widely in almost every field, it has largely brought a breakthrough in biological sciences as it is used in disease diagnosis and clinical trials. DL can be clubbed with machine learning, but at times both are used individually as well. DL seems to be a better platform than machine learning as the former does not require an intermediate feature extraction and works well with larger datasets. DL is one of the most discussed fields among the scientists and researchers these days for diagnosing and solving various biological problems. However, deep learning models need some improvisation and experimental validations to be more productive. Objective: To review the available DL models and datasets that are used in disease diagnosis. Methods: Available DL models and their applications in disease diagnosis were reviewed discussed and tabulated. Types of datasets and some of the popular disease related data sources for DL were highlighted. Results: We have analyzed the frequently used DL methods, data types and discussed some of the recent deep learning models used for solving different biological problems. Conclusion: The review presents useful insights about DL methods, data types, selection of DL models for the disease diagnosis.


2021 ◽  
Vol 7 (3) ◽  
pp. 59
Author(s):  
Yohanna Rodriguez-Ortega ◽  
Dora M. Ballesteros ◽  
Diego Renza

With the exponential growth of high-quality fake images in social networks and media, it is necessary to develop recognition algorithms for this type of content. One of the most common types of image and video editing consists of duplicating areas of the image, known as the copy-move technique. Traditional image processing approaches manually look for patterns related to the duplicated content, limiting their use in mass data classification. In contrast, approaches based on deep learning have shown better performance and promising results, but they present generalization problems with a high dependence on training data and the need for appropriate selection of hyperparameters. To overcome this, we propose two approaches that use deep learning, a model by a custom architecture and a model by transfer learning. In each case, the impact of the depth of the network is analyzed in terms of precision (P), recall (R) and F1 score. Additionally, the problem of generalization is addressed with images from eight different open access datasets. Finally, the models are compared in terms of evaluation metrics, and training and inference times. The model by transfer learning of VGG-16 achieves metrics about 10% higher than the model by a custom architecture, however, it requires approximately twice as much inference time as the latter.


Energies ◽  
2021 ◽  
Vol 14 (15) ◽  
pp. 4674
Author(s):  
Qingsheng Zhao ◽  
Juwen Mu ◽  
Xiaoqing Han ◽  
Dingkang Liang ◽  
Xuping Wang

The operation state detection of numerous smart meters is a significant problem caused by manual on-site testing. This paper addresses the problem of improving the malfunction detection efficiency of smart meters using deep learning and proposes a novel evaluation model of operation state for smart meter. This evaluation model adopts recurrent neural networks (RNN) to predict power consumption. According to the prediction residual between predicted power consumption and the observed power consumption, the malfunctioning smart meter is detected. The training efficiency for the prediction model is improved by using transfer learning (TL). This evaluation uses an accumulator algorithm and threshold setting with flexibility for abnormal detection. In the simulation experiment, the detection principle is demonstrated to improve efficient replacement and extend the average using time of smart meters. The effectiveness of the evaluation model was verified on the actual station dataset. It has accurately detected the operation state of smart meters.


2021 ◽  
Vol 69 (4) ◽  
pp. 297-306
Author(s):  
Julius Krause ◽  
Maurice Günder ◽  
Daniel Schulz ◽  
Robin Gruna

Abstract The selection of training data determines the quality of a chemometric calibration model. In order to cover the entire parameter space of known influencing parameters, an experimental design is usually created. Nevertheless, even with a carefully prepared Design of Experiment (DoE), redundant reference analyses are often performed during the analysis of agricultural products. Because the number of possible reference analyses is usually very limited, the presented active learning approaches are intended to provide a tool for better selection of training samples.


Author(s):  
Hao Zheng ◽  
Lin Yang ◽  
Jianxu Chen ◽  
Jun Han ◽  
Yizhe Zhang ◽  
...  

Deep learning has been applied successfully to many biomedical image segmentation tasks. However, due to the diversity and complexity of biomedical image data, manual annotation for training common deep learning models is very timeconsuming and labor-intensive, especially because normally only biomedical experts can annotate image data well. Human experts are often involved in a long and iterative process of annotation, as in active learning type annotation schemes. In this paper, we propose representative annotation (RA), a new deep learning framework for reducing annotation effort in biomedical image segmentation. RA uses unsupervised networks for feature extraction and selects representative image patches for annotation in the latent space of learned feature descriptors, which implicitly characterizes the underlying data while minimizing redundancy. A fully convolutional network (FCN) is then trained using the annotated selected image patches for image segmentation. Our RA scheme offers three compelling advantages: (1) It leverages the ability of deep neural networks to learn better representations of image data; (2) it performs one-shot selection for manual annotation and frees annotators from the iterative process of common active learning based annotation schemes; (3) it can be deployed to 3D images with simple extensions. We evaluate our RA approach using three datasets (two 2D and one 3D) and show our framework yields competitive segmentation results comparing with state-of-the-art methods.


Complexity ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Minyu Shi ◽  
Yongting Zhang ◽  
Huanhuan Wang ◽  
Junfeng Hu ◽  
Xiang Wu

The innovation of the deep learning modeling scheme plays an important role in promoting the research of complex problems handled with artificial intelligence in smart cities and the development of the next generation of information technology. With the widespread use of smart interactive devices and systems, the exponential growth of data volume and the complex modeling requirements increase the difficulty of deep learning modeling, and the classical centralized deep learning modeling scheme has encountered bottlenecks in the improvement of model performance and the diversification of smart application scenarios. The parallel processing system in deep learning links the virtual information space with the physical world, although the distributed deep learning research has become a crucial concern with its unique advantages in training efficiency, and improving the availability of trained models and preventing privacy disclosure are still the main challenges faced by related research. To address these above issues in distributed deep learning, this research developed a clonal selective optimization system based on the federated learning framework for the model training process involving large-scale data. This system adopts the heuristic clonal selective strategy in local model optimization and optimizes the effect of federated training. First of all, this process enhances the adaptability and robustness of the federated learning scheme and improves the modeling performance and training efficiency. Furthermore, this research attempts to improve the privacy security defense capability of the federated learning scheme for big data through differential privacy preprocessing. The simulation results show that the proposed clonal selection optimization system based on federated learning has significant optimization ability on model basic performance, stability, and privacy.


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