scholarly journals Vitamin D, adipose tissue, and obesity

2013 ◽  
Vol 15 (3) ◽  
Author(s):  
Julie Marcotorchino ◽  
Franck Tourniaire ◽  
Jean-François Landrier
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Adipose Tissue ◽  
Cardiovascular Diseases ◽  
Vitamin D Deficiency ◽  
Epidemiological Studies ◽  
The Relationship ◽  
Diabetes And Obesity

AbstractEpidemiological studies have shown a link between vitamin D deficiency and numerous pathologies such as cancers, immunity diseases, cardiovascular diseases, hypertension, type 2 diabetes, and obesity. Recent studies in vitro and in animal models demonstrated an impact of vitamin D on adipose tissue and adipocyte biology. Such observations are of particular interest and provide mechanistic explanations on the relationship between vitamin D deficiency and obesity.

scholarly journals The relationship between microvascular complications and vitamin D deficiency in type 2 diabetes mellitus

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Celil Alper Usluogullari ◽  
Fevzi Balkan ◽  
Sedat Caner ◽  
Rifki Ucler ◽  
Cafer Kaya ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Vitamin D Deficiency ◽  
Microvascular Complications ◽  
The Relationship

scholarly journals The Relationship of Vitamin D Deficiency in Type 2 Diabetes Patients: Dhaka, Bangladesh

2021 ◽  
Vol 7 (3) ◽  
pp. 79-84
Author(s):  
  Dr. Amal Krishna Paul ◽  
Dr. Arifa Sultana ◽  
Dr. Ismat Ara Begum
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Relationship Of ◽  
The Relationship ◽  
Diabetes Patients

The Relationship between Vitamin D and Type 2 Diabetes Is Intriguing: Glimpses from the Spect-China Study

2017 ◽  
Vol 71 (3-4) ◽  
pp. 195-202 ◽  
Author(s):  
You Lu ◽  
Yanjun Zheng ◽  
Ningjian Wang ◽  
Yingchao Chen ◽  
Qin Li ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Multinomial Logistic Regression ◽  
East China ◽  
Model Assessment ◽  
Body Type ◽  
The People ◽  
The Relationship

Objective: Vitamin D is a multifunctional vitamin for our body. Type 2 diabetes mellitus (T2DM) is a common metabolic disease. Whether T2DM affects the serum 25(OH)D level has not been reported. The objective of this study was to reveal the extent to which vitamin D is present in the population in East China and to explore the relationship between serum 25(OH)D and T2DM. Methods: The cohort was selected based on a large investigation named Survey on Prevalence in East China including 12,702 participants aged 21-92 years old. All the participants completed the questionnaire and went through a physical examination. Fasting blood samples were collected to test serum 25(OH)D and other metabolism-related indicators. AVONA was used to test the significance of differences among groups. Multinomial logistic regression was used to assess the association of T2DM with serum 25(OH)D level. Results: The overall percentage of vitamin D deficiency was 80.55% (male 74.1%, female 85.0%). Men with lower serum 25(OH)D level had high value in homeostasis model assessment of insulin resistance and HbA1c. The serum 25(OH)D level of those who were diagnosed with T2DM was higher than that in non-diabetics. The serum 25(OH)D level of pre-diabetes was the highest. T2DM patients trended to have higher serum 25(OH)D levels. Conclusion: Vitamin D deficiency is common among the people in East-China. T2DM patients had higher levels of serum 25(OH)D. The relationship between vitamin D and T2DM is intriguing. It seemed that vitamin D was either irrelevant directly to T2DM or resisted in T2DM patients.

RELATIONSHIP BETWEEN VITAMIN D DEFICIENCY AND CARDIOVASCULAR DISEASES (REVIEW)

Vestnik ◽  
2021 ◽  
pp. 40-43
Author(s):  
А.М. Барат ◽  
Г.Д. Жаманбай ◽  
Б.Б. Тельман ◽  
А.Б. Кенесхан ◽  
Д.К. Досиханова ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Cardiovascular Diseases ◽  
Vitamin D Deficiency ◽  
The World ◽  
Associated Risk Factors

Дефицит витамина D, а также сердечно-сосудистые заболевания (ССЗ) и связанные с ними факторы риска широко распространены во всем мире и часто возникают одновременно. Давно известно, что витамин D является неотъемлемой частью метаболизма костей, хотя недавние данные свидетельствуют о том, что витамин D играет ключевую роль в патофизиологии других заболеваний, включая сердечно-сосудистые заболевания. В этом обзоре мы стремимся обобщить самые последние данные об участии дефицита витамина D в развитии основных факторов риска сердечно-сосудистых заболеваний: артериальной гипертензии, ожирения и дислипидемии, диабета 2 типа, хронического заболевания почек и эндотелиальной дисфункции. Кроме того, мы приводим самые последние данные наблюдений, а также интервенционные данные о влиянии витамина D на сердечно-сосудистые заболевания. Vitamin D deficiency, as well as cardiovascular disease (CVD) and associated risk factors, are widespread throughout the world and often occur concurrently. Vitamin D has long been known to be an essential part of bone metabolism, although recent evidence suggests that vitamin D plays a key role in the pathophysiology of other diseases, including cardiovascular disease. In this review, we seek to summarize the most recent evidence on the involvement of vitamin D deficiency in the major risk factors for cardiovascular disease: hypertension, obesity and dyslipidemia, type 2 diabetes, chronic kidney disease, and endothelial dysfunction. In addition, we provide the most recent observational data as well as interventional evidence on the effects of vitamin D on cardiovascular disease.

High Prevalence of Vitamin D Deficiency and Correlation with Cystatin-C and Other Cardiovascular and Renal Risk Biomarkers in Patients with Type 2 Diabetes Mellitus Complicated with Hypertension

2020 ◽  
Vol 17 (1) ◽  
pp. 81-90
Author(s):  
Mohammad J. Alkhatatbeh ◽  
Sajedah A. Smadi ◽  
Khalid K. Abdul-Razzak ◽  
Nesreen A. Saadeh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Vitamin D Deficiency ◽  
Cystatin C ◽  
P Values ◽  
Renal Biomarkers ◽  
Risk Biomarkers

Background: Vitamin D is increasingly investigated as having a role in Type 2 Diabetes Mellitus (T2DM) and its cardiovascular and renal complications. Objective: This study aimed to investigate the association between 25-hydroxyvitamin D (25-OHD) and biomarkers of cardiovascular and renal complications, including cystatin-C. Methods: This cross-sectional study involved 117 participants with T2DM that was not complicated with cardiovascular or renal diseases except hypertension. 25-OHD was measured by electrochemiluminescence immunoassay, while cystatin-C was measured by enzyme-linked-immunosorbent-assay. Other biomarkers, including lipids, creatinine, urea and glycemic measures, were determined by the routine biochemistry assays. Results: The prevalence of vitamin D deficiency was 74.36%. There was no significant difference in cardiovascular and renal biomarkers, including glucose, HbA1c, lipids, urea, creatinine and cystatin-C between participants with adequate and deficient vitamin D (p-values>0.05). Participants with adequate vitamin D were older in age, more obese and having lower eGFR (p-values<0.05). 25-OHD was weakly correlated with age, duration of DM, urea, creatinine and inversely correlated with eGFR (rvalues< 0.32, p-values<0.05). Although creatinine and cystatin-C were directly correlated (r=0.42, pvalue< 0.001), cystatin-C and 25-OHD were not correlated (p-value>0.05). Hypertensive participants were more obese, having a longer duration of DM and higher urea and cystatin-C compared to nonhypertensive participants (p-values<0.05). Binary logistic regression analysis revealed that hypertension could be predicted from increased BMI. Conclusion: 25-OHD was not found to be correlated with cardiovascular risk biomarkers, but it was correlated with renal biomarkers, including urea, creatinine and eGFR. Cystatin-C and 25-OHD were not observed to be correlated to each other, but both were correlated to renal function. Obesity was a significant predictor of hypertension.

Sign in / Sign up

Export Citation Format

Share Document