scholarly journals Staphylococcal Scalded Skin Syndrome in Child. A Case Report and a Review from Literature

2016 ◽  
Vol 2 (4) ◽  
pp. 192-197 ◽  
Author(s):  
Alina Grama ◽  
Oana Cristina Mărginean ◽  
Lorena Elena Meliț ◽  
Anca Meda Georgescu

Abstract Staphylococcal scalded skin syndrome (SSSS) is the medical term used to define a skin condition induced by the exfoliative toxins produced by Staphylococcus aureus. The disorder is also known as Ritter disease, bullous impetigo, neonatal pemphigus, or staphylococcal scarlet fever. The disease especially affects infants and small children, but has also been described in adults. Prompt therapy with proper antibiotics and supportive treatment has led to a decrease in the mortality rate. The current case report describes the clinical progress of a patient with generalized erythema and fever, followed by the appearance of bullous lesions with tendency to rupture under the smallest pressure, and with extended areas of denudation. The patient aged four years and six months was admitted to our clinic to establish the aetiology and treatment of a generalized bullous exanthema, followed by a skin denudation associated with fever and impaired general status. Based on clinical and paraclinical examinations a diagnosis of Staphylococcal scalded skin syndrome was established which responded favourably to antibiotic treatment, hydro-electrolytic re-equilibration, and adequate local hygiene. Staphylococcal infection can represent a problem of significant pathological importance sometimes requiring a multidisciplinary approach involving paediatricians, dermatologists, infectious diseases specialists, and plastic surgeons.

2019 ◽  
Vol 1 (1) ◽  
pp. 4-6
Author(s):  
Elharrouni A ◽  
Elimam M ◽  
Dassouly R ◽  
Hnach KH ◽  
Elloudi S ◽  
...  

Staphylococcus aureus can cause exfoliative skin conditions, ranging from localized bullous impetigo (BI) to staphylococcal scalded skin syndrome (SSSS). The latter is a potentially life-threatening disorder, which leads to blistering of the upper layer of the skin, by the release of a circulating exotoxin. The disease especially affects infants and small children but has also been described in adults. SSSS usually presents with a prodrome of sore throat or conjunctivitis. The infection is often peri-facial impetigo, here is usually no bacteremia. Bullous impetigo, the toxin produces blisters locally at the site of infection, whereas in cases of the scalded-skin syndrome, it circulates throughout the body, causing blisters at sites distant from the infection.


PEDIATRICS ◽  
1980 ◽  
Vol 66 (2) ◽  
pp. 285-290
Author(s):  
John P. Curran ◽  
Farouk L. Al-Salihi

A massive outbreak of the staphylococcal scalded skin syndrome due to an organism with an unusual phage pattern, occurred during a 115-day period and involved 68 newborns. Generalized exfoliative dermatitis was seen in 24 babies, and Staphylococcus aureus was isolated from 23. Fourteen isolates were phage typed, with 13 reported as the epidemic strain 29/79/80/3A/3C/54/75. Eight babies had generalized scarlatiniform eruption without exfoliation (staphylococcal scarlet fever). Cultural data were available from six, all positive for S aureus. Four organisms were typed and reported as the epidemic strain. Of 34 infants with bullous impetigo 20 had cultures that were positive for S aureus, and four were phage typed, revealing the epidemic strain. Illness was mild in all patients; there were no deaths and no invasive forms of staphylococcal infection. The male to female ratio of generalized exfoliative disease was 5:1. The concept of a neonatal staphylococcal scalded skin syndrome, comprised of a triad of skin disorders induced by an exotoxin elaborated by certain strains of coagulase positive S aureus, is confirmed.


2016 ◽  
Vol 65 (3) ◽  
pp. 253-259 ◽  
Author(s):  
Jacek Międzobrodzki

Staphylococcus aureus colonizes the mucous membrane of the nasal vestibule of a significant number of healthy people. These microorganisms are opportunistic pathogens, that in favorable conditions, may cause infections of various course, location or manifestation. Secondary infections emerge in cases when other risk factors contribute to such a change. One of the diseases during which S. aureus changes its saprophytic character to a pathogenic one is atopic dermatitis (AD), an allergic skin condition of a chronic and recurrent nature. Patients with AD are highly predisposed to secondary staphylococcal infections due to active S. aureus colonization of the stratum corneum, damage of the skin barrier or a defective immune response. Microorganisms present in skin lesions destroy the tissue by secreting enzymes and toxins, and additionally stimulate secondary allergic reactions. The toxins secreted by strains of S. aureus also act as superantigens and penetrate the skin barrier contributing to a chronic inflammation of the atopic skin lesions. The S. aureus species also releases proinflammatory proteins, including enzymes that cause tissue damage. When initiating treatment it is particularly important to properly assess that the onset of the secondary bacterial infection is caused by S. aureus and thus justifying the inclusion of antibiotic therapy. Depending on the severity and extent of the staphylococcal infection, topical antibiotics are used, usually mupirocin or fusidic acid, or general antibiotic treatment is introduced. Another therapeutic strategy without antibiotics has given a positive effect in patients.


2015 ◽  
Vol 133 (5) ◽  
pp. 450-453 ◽  
Author(s):  
Andreas Hörner ◽  
Rosmari Hörner ◽  
Adenilde Salla ◽  
Melise Silveira Nunes ◽  
Litiérri Razia Garzon ◽  
...  

CONTEXT: Staphylococcal scalded skin syndrome is an exfoliative skin disease. Reports of this syndrome in newborns caused by methicillin-resistant Staphylococcus aureus are rare but, when present, rapid diagnosis and treatment is required in order to decrease morbidity and mortality. CASE REPORT: A premature newly born girl weighing 1,520 g, born with a gestational age of 29 weeks and 4 days, developed staphylococcal scalded skin syndrome on the fifth day of life. Cultures on blood samples collected on the first and fourth days were negative, but Pseudomonas aeruginosa and Enterococcus sp. (vancomycin-sensitive) developed in blood cultures performed on the day of death (seventh day), and Pseudomonas aeruginosa and Serratia marcescens were identified in cultures on nasopharyngeal, buttock and abdominal secretions. In addition to these two Gram-negative bacilli, methicillin-resistant Staphylococcus aureus was isolated in a culture on the umbilical stump (seventh day). The diagnosis of staphylococcal scalded skin syndrome was based on clinical criteria.


Author(s):  
Mayuri Gogoi ◽  
Nilakshi Borah ◽  
Ajanta Sharma

Staphylococcal scalded skin syndrome (SSSS) or acute staphylococcal epidermolysis is an exfoliative skin disease and a toxin mediated staphylococcal infection affecting mostly neonates and adolescents. We describe here a case of 10-day old full term, vaginally delivered baby weighing 1530gms presenting with erythematous lesions first developing on the face and later spreading to the entire body for the last 6 days. The mucosal areas were spared. Blood culture of the patient revealed growth of Methicllin Resistant Staphylococcus aureus (MRSA). Culture from the skin lesions also revealed growth of MRSA with similar antibiotic sensitivity pattern. Fungal culture from the skin lesions revealed growth of Candida tropicalis. The diagnosis of SSSS was based on clinical criteria and microbiological findings. 


ORL ro ◽  
2018 ◽  
Vol 3 (40) ◽  
pp. 26
Author(s):  
Daniela Vrînceanu ◽  
Bogdan Bănică ◽  
Matei Dumitru ◽  
Bogdan Dorobăț ◽  
Cristina Tudor ◽  
...  

2017 ◽  
Vol 13 (2) ◽  
pp. 293-295
Author(s):  
Deepika Kapoor ◽  
Deepanshu Garg

Orofacial clefts (OFC) are one of the most common congenital problems seen with a very high incidence. It imparts a negative effect on the overall health of the child by hindering in his feeding practices, normal facial growth, development of dentition and hence speech. Infants born with orofacial clefts have oronasal communication which creates a problem with the creation of negative pressure inside the oral cavity required for suckling.The treatment for such patients is with the multidisciplinary approach but the preliminary  concern for the neonate is to help with the feeding for which a feeding appliance is given. This case report presents a case of a 3-day old infant to whom a feeding appliance was given to aid in suckling. 


2002 ◽  
Vol 8 (3) ◽  
pp. 256-261 ◽  
Author(s):  
Yoichiro Ito ◽  
Katsuhisa Toda ◽  
Makoto Shimazaki ◽  
Toshiyuki Nakamura ◽  
Miyuki Funabashi Yoh ◽  
...  

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