scholarly journals Dual-Energy X - Rayabsorptiometry (Dxa) Assessment of Body Composition and Body Fat Distribution in Cushing’s Women

2015 ◽  
Vol 69 (2) ◽  
pp. 86-93
Author(s):  
Slavica Shubeska-Stratrova ◽  
Snezana Markovik-Temelkova ◽  
Goran Petrovski
Keyword(s):  
Body Composition ◽  
Body Mass ◽  
Body Fat ◽  
Fat Distribution ◽  
Dual Energy ◽  
Body Fat Distribution ◽  
Mineral Density ◽  
Tissue Mass ◽  
Healthy Control ◽  
Show Difference

AbstractIntroduction. Body composition and body fat distribution show difference in women with Cushing's syndrome (CS) compared to healthy control women (C) with almost equal body mass index (BMI) (28.89±3.53kg/m2vs. 29.39±4.04kg/m2) and they were compared with DXA.Methods. Total and regional fat mass (FM), FM%, tissue mass (TM), TM%, android FM (A), gynoid FM (G), lean body mass (LBM), bone mineral density (BMD) and content (BMC) were determined as well as their relationships in 10 CS and 10 C women.Results. Regional FM, FM%, TM and TM% values were not different between CS and C except for arm TM % (45.06±3.1% vs. 40.23±6.29%) (p<0.043). Arms+legs/trunk TM and FM ratio were significantly lower in CS compared to C (p<0.0001). Arms/A (1.1±0.12), legs/A (3±0.41) and legs/trunk TM ratios (0.52±0.07) were significantly lower in CS compared to C (1.3±0.13) (p<0.002), (4.29 ±0.67) (p<0.0001) and (0.69±0.09) (p<0.0001). Legs/A (2.57±0.73), legs/trunk (0.48±0.13) and arms+legs/trunk FM ratio (0.66±0.14) in CS were significantly lower compared to C [(4.2±1.16; 0.71±0.12 (p<0.001) and 0.89±0.14 (p<0.002)]. A/GTM (0.67±0.1) and A/G FM ratio (0.72± 0.2) in CS were significantly higher compared to C (0.48±0.05) (p<0.0001) and (0.46±0.09) (p<0.001). Legs LBM in CS 10.8±1.95kg was lower compared to C 12.7±2.1 kg (p<0.046). Only spine BMD value in CS (0.89±0.09 kg/cm2) was lower compared to C (0.94±0.12 kg/cm2) (p<0.017).Conclusion. Central to peripheral regional TM, FM and LBM ratios differentiated significantly and precisely patients with CS and C and confirmed extreme central obesity in CS.

Body Fat Distribution and Body Composition During GnRH Agonist Therapy

2001 ◽  
Vol 97 (3) ◽  
pp. 338-342 ◽  
Author(s):  
HIDEKI YAMASAKI ◽  
TSUTOMU DOUCHI ◽  
SHINAKO YAMAMOTO ◽  
TOSHIMICHI OKI ◽  
RIKI KUWAHATA ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
Gnrh Agonist ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Agonist Therapy

scholarly journals Association of prenatal exposure to gestational diabetes with offspring body composition and regional body fat distribution

2017 ◽  
Vol 8 (2) ◽  
pp. 81-87 ◽  
Author(s):  
M. Kearney ◽  
J. Perron ◽  
I. Marc ◽  
S. J. Weisnagel ◽  
A. Tchernof ◽  
...  
Keyword(s):  
Body Composition ◽  
Gestational Diabetes ◽  
Body Fat ◽  
Prenatal Exposure ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Regional Body Fat

scholarly journals Lean Body Mass and Body Fat Distribution in Participants With Chronic Low Back Pain

2000 ◽  
Vol 160 (21) ◽  
pp. 3265 ◽  
Author(s):  
Yoshitaka Toda ◽  
Neil Segal ◽  
Tamami Toda ◽  
Tadanobu Morimoto ◽  
Ryokei Ogawa
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Chronic Low Back Pain ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Low Back

scholarly journals Changes in Body Fat Distribution in Antiretroviral-Naive HIV-Positive Individuals Initiating Current ART Regimens

2018 ◽  
Vol 104 (3) ◽  
pp. 900-905 ◽  
Author(s):  
Juan Tiraboschi ◽  
Antonio Navarro-Alcaraz ◽  
Dolors Giralt ◽  
Carmen Gomez-Vaquero ◽  
Maria Saumoy ◽  
...  
Keyword(s):  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
The Body ◽  
Strand Transfer ◽  
Mass Ratio ◽  
Total Fat ◽  
Fat Mass Ratio

Abstract Objectives To describe the changes in body fat distribution (BFD) occurring over 60 months in a group of antiretroviral therapy (ART)-naive individuals starting different antiretroviral regimens. Methods A prospective ongoing fat change assessment including clinical evaluation and dual X-ray absorptiometry scan is being conducted in all consecutive patients initiating ART from January 2008. Arm, leg, trunk, and total fat as well as fat mass ratio were determined. Results A total of 146 patients were included (80% male, 40% MSM). Mean age was 44 years, HIV-1 RNA was 4.98 log10 copies/mL, and CD4 count was 254 cells/μL. The most common initial antiretroviral combination included non-nucleoside reverse transcription inhibitor (NNRTI) drugs followed by protease inhibitor (PI) and integrase strand transfer inhibitor (INSTI)-based regimens. At month 36, an increase was seen in the body mass index (BMI), total fat, trunk fat, and limb fat. The fat mass ratio (FMR) also showed a significant increase in both men and women (P = 0.001). In patients receiving NNRTI- or INSTI-based regimens (but not PIs), there was a marginal but statistically significant increase in the FMR (0.10 and 0.07, respectively; P = 0.01). Sixty-two subjects completed 60 months of follow-up. FMR showed a significant increase even in the PI group at this time point (P &lt; 0.03). Conclusions We observed a significant increase in the fat and lean body mass in all compartments and treatment groups over 36 and 60 months. Clinically irrelevant differences were found in fat distribution regardless of the treatment group and baseline characteristics. The data suggest that current antiretroviral regimens have little impact on BFD during the first years of treatment.

Relationship of upper body fat distribution to higher regional lean mass and bone mineral density

2003 ◽  
Vol 21 (3) ◽  
pp. 179-183 ◽  
Author(s):  
Takashi Matsuo ◽  
Tsutomu Douchi ◽  
Mitsuhiro Nakae ◽  
Hirofumi Uto ◽  
Toshimichi Oki ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Fat ◽  
Bone Mineral ◽  
Lean Mass ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Upper Body ◽  
Mineral Density ◽  
Relationship Of

scholarly journals Response of the Hypothalamic-Pituitary-Adrenocortical Axis to High-Protein/Fat and High-Carbohydrate Meals in Women with Different Obesity Phenotypes

2002 ◽  
Vol 87 (8) ◽  
pp. 3984-3988 ◽  
Author(s):  
Valentina Vicennati ◽  
Luana Ceroni ◽  
Lorenza Gagliardi ◽  
Alessandra Gambineri ◽  
Renato Pasquali
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Body Fat ◽  
Hpa Axis ◽  
Abdominal Obesity ◽  
Area Under The Curve ◽  
Fat Distribution ◽  
Normal Weight ◽  
Body Fat Distribution ◽  
High Carbohydrate

Subjects with abdominal obesity are characterized by hyperactivation of the hypothalamic-pituitary-adrenal (HPA) axis. Food intake, particularly at noon, is a well-known inducer of HPA axis activation. Whether obese subjects present an abnormal response to meals containing different macronutrient proportions is at present unknown. Therefore, this study was carried out to investigate the effect of a high-lipid/protein meal (HLP-meal) and a high-carbohydrate meal (HCHO-meal) on the HPA axis activity in women with different obesity phenotypes. Nondepressed, noncomplicated obese (body mass index greater than 28 kg/m2) women with abdominal (A-BFD) (n = 10) and peripheral body fat distribution (P-BFD) (n = 9) and a group of 11 normal-weight controls were investigated in the follicular phase of the menstrual cycle. They were randomly given an 800-kcal HCHO-meal (containing 89% carbohydrates, 11% proteins, 0% lipids), and an 800-kcal HLP-meal (containing 53% lipids, 43% proteins, 4% carbohydrates), which were eaten within 15 min at noon, with an interval of 2 d between each meal. Blood samples for ACTH, cortisol, glucose, and insulin were obtained at 15-min intervals before and after each meal. Baseline hormone and glucose concentrations in the three groups were similar. After the HLP-meal, ACTH tended to similarly but insignificantly increase in all groups, whereas cortisol increased significantly (P &lt; 0.05) in the P-BFD group and insignificantly in the other groups. Conversely, both ACTH and cortisol significantly (P &lt; 0.05) increased only in the A-BFD group, without any significant changes in both controls and P-BFD women. The analysis of the interaction between meals and groups clearly indicated that the cortisol response to the HLP-meal and the HCHO-meal was significantly different (P &lt; 0.025) between the two obese groups, the A-BFD group being characterized by a significantly lower response to the HLP-meal and a significantly higher response to the HCHO-meal, compared with the P-BFD group. Considering all groups together and after adjusting for body mass index, a highly significant relationship was found between cortisol-area under the curve and ACTH-area under the curve after each meal test. However, no relationships were found between changes in ACTH and cortisol and those of glucose, insulin, and the glucose:insulin ratio after each meal. Therefore, our data demonstrate that the response of the HPA axis to meals containing different macronutrient proportions may depend on the pattern of body fat distribution. We also suggest that the activation of the HPA axis following the ingestion of large amounts of carbohydrates may have some pathophysiological relevance, specifically in women with the abdominal obesity phenotype.

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